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An Evolutionary and Environmental Perspective of the Interaction of Nanomaterials with the Immune System-The Outcomes of the EU Project PANDORA
| An Evolutionary and Environmental Perspective of the Interaction of Nanomaterials with the Immune System-The Outcomes of the EU Project PANDORA |
| Autore | Boraschi Diana |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 electronic resource (218 p.) |
| Soggetto topico |
Medicine
Pharmacology |
| Soggetto non controllato |
innate immunity
infection microbiome survival nanomaterials nanoparticles copper earthworms Eisenia fetida cosmetic formulation cosmetic lifecycle hydrophobic compound nano-TiO2 nano safety marine invertebrate metabolomics avian pathogenic Escherichia coli nanovaccine outer membrane vesicles immune response broiler earthworm coelomocyte TiO2 nanoparticles reactive oxygen species lipid peroxidation alkaline comet assay phagocytosis apoptosis gene expression hemocytes Mytilus in vitro scanning electron microscopy innate memory Schistosoma mansoni monocytes macrophages vaccination gold nanoparticles cerium nanoparticles woodlice haemocyte environmental models human cells markers NPs testing immune system inflammation tolerance engineered nanomaterial (ENM) nanoparticle (NP) gold nanoparticle (AuNP) plant Arabidopsis thaliana plant growth stress response transcriptomics proteomics |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910576882703321 |
Boraschi Diana
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Anticancer Drugs 2021
| Anticancer Drugs 2021 |
| Autore | Meegan Mary J |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 electronic resource (594 p.) |
| Soggetto topico |
Research & information: general
Chemistry |
| Soggetto non controllato |
thymidylate synthase
cytotoxicity 1,2,3-triazole 1,3,4-oxadiazole 5-fluoruracil pemetrexed docking 3,4'-bis-guanidino 3-amino-4'-guanidino diphenyl ether phenyl pyridyl ether intramolecular hydrogen bond cancer cell viability HL-60 BRAF apoptosis thieno[2,3-d][1,2,3]triazine acetamide H1299 HER2 EGFR Bcl-2 inhibitors Indole-based analogues benzimidazole MTT cytotoxic assay cell cycle analysis DNA fragmentation ELISA solid/lipid nanoparticles phenstatin letrozole tubulin polymerisation inhibitor aromatase inhibitor breast cancer hybrid molecule dual-targeting molecule designed multiple ligand NaMSA cyclophosphamide histopathology testis urinary bladder anticancer agents enantioselective synthesis gastric adenocarcinoma tryptophanol concentration-guided dosing model informed dosing physiologically based pharmacokinetics sorafenib tyrosil-DNA-phosphodiesterase 1 adamantane resin acid TDP1 cytotoxic agents apoptosis induction HT-29 cells MDA-MB-231 cells mechanism prediction STAT inhibitors miR-21 hydrazide derivatives nitrogen scaffolds mitoxantrone cardiotoxicity inflammation oxidative stress age cumulative dose Trk NTRK tissue-agnostic larotrectinib entrectinib Trk fusion protein kinase inhibitors USFDA cancer patent review generic product doxazosin MD simulations combretastatin A-4 cytotoxic activity hybrid compounds indazole mucin MUC1 MUC16 immunotherapy cancer vaccine CAR (chimeric antigen receptor) ADC (antibody-drug conjugate) thiourea interleukin-6 trypan blue assay chalcones exportin-1 covalent binding CovDock anticancer activity xanthone in vitro in vivo isolation synthesis heterocyclic compound benzenesulfonamides imidazoles alkylated colony formation tumor spheroids HDAC inhibitors chalcone dual inhibitors carvedilol kidney toxicity 7-deaza-4'-thioadenosine derivatives multi-kinase inhibitor anticancer nucleoside Imiquimod drug efflux multidrug resistance Toll-Like Receptor |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910576874303321 |
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Meegan Mary J
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Bioactive Compounds from Natural Products: Separation, Characterization and Applications
| Bioactive Compounds from Natural Products: Separation, Characterization and Applications |
| Autore | Vamanu Emanuel |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 electronic resource (204 p.) |
| Soggetto topico |
Technology: general issues
Biotechnology |
| Soggetto non controllato |
in vitro callus
cell suspension and root cultures biologically active substances ecdysteroids HPLC 1H NMR spectra Rhaponticum carthamoides Chaga medicinal fungi biomass yield mathematical modeling response surface methodology bioreactor culture mycelium antioxidant activity gamma irradiation Fomes fomentarius mushroom DPPH flavonoids polyphenols urinary infection in vitro Escherichia coli antimicrobial yellow onion skins extraction multifunctional ingredients Ficus carica L. ultrasonic enzyme co-assisted aqueous two-phase extraction UPLC-QTOF-MS/MS identification lactic acid fermentation betalain carotenoids red pepper beetroot carrot drying heat treatment seaweeds bioactive compounds food safety consumer health Cannabis sativa L. cannabinoids hemp oil UHPLC-PDA validation Cnidoscolus aconitifolius inflammation croton oil HL-60 phenols differentiation apoptosis transcriptome natural products bacteria downstream processing antibiotics isolation secondary metabolites pharmacognosy bioprospecting U. lactuca non-toxic solvents phenolics uropathogenic herbal medicines plant extract bioactive molecules |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | Bioactive Compounds from Natural Products |
| Record Nr. | UNINA-9910576876703321 |
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Vamanu Emanuel
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Biological Efficacy of Natural and Chemically Modified Products against Oral Inflammatory Lesions
| Biological Efficacy of Natural and Chemically Modified Products against Oral Inflammatory Lesions |
| Autore | Sakagami Hiroshi |
| Pubbl/distr/stampa | MDPI - Multidisciplinary Digital Publishing Institute, 2019 |
| Descrizione fisica | 1 electronic resource (212 p.) |
| Soggetto non controllato |
gargle
oral lichen planus angiotensin II blocker quantitative structure-activity relationship metabolomics CCN2 anti-human immunodeficiency virus (HIV) oral cell arachidonic acid cascade Kampo medicine lignin-carbohydrate complex traditional medicine eugenol QSAR analysis constituent plant extract polyphenol benzaldehyde glucosyltransferase infective endocarditis antiviral periodontitis nutritionally variant streptococci Kampo quantitative structure-activity relationship (QSAR) analysis traditional Japanese herbal medicine technical terms allergic rhinitis nasal epithelial cell antimicrobial susceptibilities alkaline extract mastic stomatitis thioredoxin production oral microbiota Jixueteng oral inflammation random forest mice chromone natural products Chinese herbal remedies inflammation quercetin in vivo kampo formula glucocorticoids Hangeshashinto recurrent aphthous stomatitis anti-osteoclast activity cytotoxicity dental application tongue diagnosis natural product alkaloids inflammatory disease pathogenic factors increase machine learning human virus cepharanthin mucositis oral diseases Juzentaihoto in vitro herbal medicine tumour-specificity |
| ISBN | 3-03897-993-7 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910346850803321 |
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Sakagami Hiroshi
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| MDPI - Multidisciplinary Digital Publishing Institute, 2019 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Cancer Metabolomics 2018
| Cancer Metabolomics 2018 |
| Autore | Pinto Joana |
| Pubbl/distr/stampa | MDPI - Multidisciplinary Digital Publishing Institute, 2019 |
| Descrizione fisica | 1 electronic resource (184 p.) |
| Soggetto non controllato |
cell transporters
pharmacodynamics cell growth in vitro study metabolomic signatures endometabolome lung cancer metabolomics chemometric methods bladder cancer mTOR metabolite profiling metabolic pathways hepatocellular carcinoma glutamate senescence MCF7 breath analysis bio actives biomarker gas chromatography–mass spectrometry (GC–MS) GC-MS lung omics nutraceuticals glutaminase metabolism acylcarnitines Erwinaze Kidrolase glutathione targeted metabolomics apoptosis SLC1A5 essential amino acids cancer progression ASCT2 HR MAS alanine analytical platforms volatile organic compound glutaminolysis isotope tracing analysis asparaginase vitamin E breast cancer prognosis early diagnosis tocotrienols NMR prostate cancer in vitro cancer MDA-MB-231 |
| ISBN | 3-03921-346-6 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910367563603321 |
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Pinto Joana
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| MDPI - Multidisciplinary Digital Publishing Institute, 2019 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Cancer Nanomedicine
| Cancer Nanomedicine |
| Autore | Hoskins Clare |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 |
| Descrizione fisica | 1 electronic resource (510 p.) |
| Soggetto topico | Technology: general issues |
| Soggetto non controllato |
antibody drug conjugate (ADC)
PD-L1 tumor spheroid disruption immune modulation doxorubicin graphene oxide adsorption cathepsin D cathepsin L anti-metastatic enzyme cancer therapy nanoparticles targeted delivery system siRNA osteopontin mammary carcinoma mesenchymal stem cells (MSCs) TAT peptide PLGA paclitaxel nano-engineered MSCs orthotopic lung tumor model intracranial glioma immunotherapy CPMV viral nanoparticles in situ vaccine albumin nanoparticles microbubble ultrasound theranostics hepatocellular carcinoma VX2 tumor intra-arterial chemotherapy lung cancer nanomedicine clinical status cancer therapy breast cancer cell signaling active targeting passive targeting EPR effect oncogenes nanoparticle drug delivery ligand tumor targeting biodistribution Mesoporous silica nanoparticle drug delivery system target treatment lanthanide metal hyaluronic acid hyaluronidase drug combination everolimus dual-targeting magnetic nanoparticles monoclonal antibodies nanostructured lipid carrier platelet membrane biomimicry plasmonic photothermal therapy gold nanorods surgery bleeding dogs cats stimuli-responsive DOX SN38 CSCs single-walled carbon nanotubes chirality separation NASH drug-gene delivery near IR hyperspectral imaging plasmonics copper VEGF glioblastoma differentiated neuroblastoma peptidomimetics real-time quantitative polymerase chain reaction (qPCR) actin combinatorial therapy anticancer and antibacterial activity temoporfin drug-in-cyclodextrin-in-liposome hybrid nanoparticles multicellular tumor spheroids cyclodextrins photodynamic therapy article yet reasonably common within the subject discipline antitumor strategy biomimetic core–shell nanoparticles NK cell-derived exosomes folate receptor albumin nanoparticle microfluidic cabazitaxel polydopamine nanoparticles size cytotoxicity iron affinity FA-DABA-SMA self-assembly oncogenic proteins intracellular disruption folic receptor alpha pancreatic cancer parvifloron D albumin erlotinib photodynamic therapy lipid nanoparticles tumor vectorization verteporfin ovarian carcinomatosis spheroids integrin RGD peptide cancer diagnosis radiotherapy hyperthermia therapy biomimetic nanocarrier membrane-wrapped cancer targeted delivery photothermal therapy imaging cancer nanomedicine tumor microenvironment nano–bio interactions clinical translation magnetic nanowires magnetic hyperthermia magnetic actuation magnetic drug targeting titanate nanotubes gold nanoparticles vectorization colloidal stability docetaxel prostate cancer mangiferin anti-topoisomerase activity extracellular vesicles exosomes chemico-physical functionalization loading translational medicine nanotechnology: bioengineering anacardic acid mitoxantrone targeted drug delivery liposomes melanoma apoptosis ascorbic acid angiogenesis epithelial-to-mesenchymal transition hypoxia immunosuppression metabolism nanotherapeutics tumour microenvironment DNA origami liposome remote loading acute toxicity organoids magnetic silica-coated iron oxide nanochains photothermal treatment hyperthermia collagen cellular microenvironment lymphadenectomy magnetometer sentinel lymph node dissection SPION superparamagnetic iron oxide nanoparticles Vδ2 T cells zoledronic acid polymeric nanoconstruct anti-tumor immunity colorectal carcinoma β-cyclodextrin nanosponges BALB-neuT mice brain tumours glioma blood brain barrier polymeric nanoparticles PEGylation dioleoylphosphatidylethanolamine poly(hydroxyethyl acrylate-co-allyl methyl sulfide) copolymer folate oxidation-sensitive release cellular interaction in vitro anti-cancer activity triple negative breast cancer organotin mesoporous silica nanoparticles MDA-MB-231 theranostic nanomaterials nanobiotechnology molecular imaging nanosystems nanomicelles ovarian cancer tumour targeting chemotherapeutics riboflavin vitamin B2 nanomedicines secondary structure mixed micelle pH responsive targeted therapy anti-cancer shear stress flow in vitro therapeutics diagnostics Immunotherapy |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557114703321 |
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Hoskins Clare
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Cholinesterase Research
| Cholinesterase Research |
| Autore | Korabecny Jan |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 electronic resource (223 p.) |
| Soggetto topico | Medicine |
| Soggetto non controllato |
Amaryllidaceae
Narcissus pseudonarcissus cv. Carlton alkaloids carltonine A-C Alzheimer's disease butyrylcholinesterase docking studies organophosphorus nerve agents oxime cholinesterase reactivation ventilation pharmacodynamics blood-brain barrier crossing acetylcholinesterase inhibitors bone healing osseointegration donepezil hemostasis acetylcholinesterase inhibitor dementia zebrafish behavior Alzheimer disease antioxidants butyrylcholinesterase inhibitors molecular modelling nutraceuticals phytochemicals acetylcholinesterase slow-binding inhibition transition state analog organophosphorus osmotic stress neutron scattering molecular dynamics MD simulations fluorene in vitro in silico multi-target directed ligands N-methyl-d-aspartate receptor molecular modeling reactivators reactivation process organophosphates docking hydrolysis molecular recognition catalysis inhibition |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557764703321 |
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Korabecny Jan
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Criticality as a signature of healthy neural systems [[electronic resource] ] : multi-scale experimental and computational studies / / topic editors Paolo Massobrio, Lucilla de Arcangelis, Valentina Pasquale, Henrik J. Jensen and Dietmar Plenz
| Criticality as a signature of healthy neural systems [[electronic resource] ] : multi-scale experimental and computational studies / / topic editors Paolo Massobrio, Lucilla de Arcangelis, Valentina Pasquale, Henrik J. Jensen and Dietmar Plenz |
| Autore | Dietmar Plenz |
| Pubbl/distr/stampa | Frontiers Media SA, 2015 |
| Descrizione fisica | 1 online resource (139 pages) : illustrations; digital, PDF file(s) |
| Collana |
Frontiers Research Topics
Frontiers in Systems Neuroscience |
| Soggetto topico |
Neurosciences
Nervous system Neuroscience Human Anatomy & Physiology Health & Biological Sciences |
| Soggetto non controllato |
Computational models
in vitro in vivo network dynamics self-organized criticality neuronal avalanches power law |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910137218803321 |
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Dietmar Plenz
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| Frontiers Media SA, 2015 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Cyanobacteria and Cyanotoxins: New Advances and Future Challenges
| Cyanobacteria and Cyanotoxins: New Advances and Future Challenges |
| Autore | Cameán Ana M |
| Pubbl/distr/stampa | MDPI - Multidisciplinary Digital Publishing Institute, 2020 |
| Descrizione fisica | 1 electronic resource (246 p.) |
| Soggetto non controllato |
method validation
sirtuin 1 (SIRT1) arctic Cylindrospermopsin Microcystin-LR 16S rRNA gene astaxanthin secondary metabolites shotgun metagenomic sequencing time-resolved fluoroimmunoassay Histopathological evaluation cyanobacterial thresholds akinetes nutrient enrichment benthic mats cylindrospermopsin drinking water treatment plant blue-green algae supplements lettuce genotoxicity exposure bacterial community PCR microcystin-LR marine natural compounds ELISA [d-Leu1]Microcystin-LR Paracentrotus lividus tadpoles apoptosis 16S rRNA gene sequencing PSP toxins marine cyanobacteria hemolytic essay energy budget bioassays anatoxin-a Lithobates catesbeianus mixture reproductive toxicity cyanobacteria taste-and-odor compounds Procambarus clarkii drinking water saxitoxin resveratrol harmful algal blooms cytotoxicity phylogenetic analyses Yangtze estuary microcystin mutagenicity detection Artemia salina water source cyanotoxins microcystins in vitro marine sponges microcystin-LR (MC-LR) UPLC-MS/MS reservoir microbial metabolisms Aphanizomenon flos-aquae monoclonal antibody oxidative stress Nostocales |
| ISBN | 3-03921-839-5 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | Cyanobacteria and Cyanotoxins |
| Record Nr. | UNINA-9910404089003321 |
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Cameán Ana M
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| MDPI - Multidisciplinary Digital Publishing Institute, 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Cytobiology of Human Prostate Cancer Cells and Its Clinical Applications
| Cytobiology of Human Prostate Cancer Cells and Its Clinical Applications |
| Autore | Ishii Kenichiro |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 |
| Descrizione fisica | 1 electronic resource (184 p.) |
| Soggetto topico | Medicine |
| Soggetto non controllato |
androgen receptor
docetaxel cabazitaxel castration-resistant prostate cancer chemotherapy P-glycoprotein EPI-002 splice variant prostate-specific antigen androgen deprivation therapy time to PSA nadir fibroblasts prostate cancer androgen sensitivity pirfenidone TGFβ1 G1 cell cycle arrest fibroblast growth factor fibroblast growth factor receptor obesity inflammation immune cells cytokine high-fat diet KIFC1 docetaxel resistance apoptosis CW069 Caveolin-1 TP53-regulated inhibitor of apoptosis 1 tumour stroma tumour microenvironment fibroblast CAF resistance radiotherapy CCL2 CCL22 CCL5 migration LSD1 epigenetics autophagy abiraterone enzalutamide testosterone castration resistant prostate cancer animal model diet fat in vitro in vivo mouse AKR1C3 hormone-naïve prostate cancer immunohistochemistry tissue microarray androgen receptor dependency fibroblast-dependent androgen receptor activation |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557116703321 |
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Ishii Kenichiro
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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