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Advance in the Treatment of Pediatric Leukemia
| Advance in the Treatment of Pediatric Leukemia |
| Autore | Handgretinger Rupert |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 electronic resource (300 p.) |
| Soggetto topico |
Research & information: general
Chemistry |
| Soggetto non controllato |
acute lymphoblastic leukemia
pediatric advances diagnosis treatment immunotherapy bispecific T-cell engager (BiTE) BCP-ALL leukemia TRAIL antibody Fc-engineering xenograft CD19 juvenile myelomonocytic leukemia RAS signaling hematopoietic stem cell transplantation 5-azacitidine myelodysplastic/myeloproliferative disorders targeted therapy ADC antibody-drug conjugate pediatric leukemia ALL AML allogeneic stem cell transplantation acute myeloid leukemia minimal residual disease conditioning regimen alternative donors B-ALL DUX4 IKZF1 PAX5 Ph-like ZNF384 NUTM1 T-ALL NOTCH1 BCL11B transcriptome genome chronic myeloid leukemia CML tyrosine kinase inhibitor immunizations COVID-19 childhood acute lymphoblastic leukemia low-risk ALL risk-stratified treatment treatment related toxicity L-asparaginase acute pancreatitis polymorphism SNV ABCC4 CFTR other extramedullary relapse lymphoblastic leukemia children prognosis evolution of CAR T cells FDA-approved CAR products TcR versus CAR limitations and complications of CAR T cell therapy future directions of CAR T cell therapy |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910576878903321 |
Handgretinger Rupert
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Advanced Computational Methods for Oncological Image Analysis
| Advanced Computational Methods for Oncological Image Analysis |
| Autore | Rundo Leonardo |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 electronic resource (262 p.) |
| Soggetto topico | Medicine |
| Soggetto non controllato |
melanoma detection
deep learning transfer learning ensemble classification 3D-CNN immunotherapy radiomics self-attention breast imaging microwave imaging image reconstruction segmentation unsupervised machine learning k-means clustering Kolmogorov-Smirnov hypothesis test statistical inference performance metrics contrast source inversion brain tumor segmentation magnetic resonance imaging survey brain MRI image tumor region skull stripping region growing U-Net BRATS dataset incoherent imaging clutter rejection breast cancer detection MRgFUS proton resonance frequency shift temperature variations referenceless thermometry RBF neural networks interferometric optical fibers breast cancer risk assessment machine learning texture mammography medical imaging imaging biomarkers bone scintigraphy prostate cancer semisupervised classification false positives reduction computer-aided detection breast mass mass detection mass segmentation Mask R-CNN dataset partition brain tumor classification shallow machine learning breast cancer diagnosis Wisconsin Breast Cancer Dataset feature selection dimensionality reduction principal component analysis ensemble method |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557353503321 |
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Rundo Leonardo
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Advances and Novel Treatment Options in Metastatic Melanoma
| Advances and Novel Treatment Options in Metastatic Melanoma |
| Autore | Facchiano Antonio |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 electronic resource (528 p.) |
| Soggetto topico | Medicine |
| Soggetto non controllato |
melanoma
invasion WNT5A MARCKS phosphorylation MANS peptide nanoparticles cell therapy tumor microenvironment sex/gender sex-hormones immunity microRNAs immunotherapy BRAF-mutant melanoma BRAF inhibitor mechanism of action targeted therapy tumour microenvironment plasmacytoid dendritic cells lactate dehydrogenase TLR interferon CXCL10 TPC2 HIPPO SOCE metastasis essential oils angiogenesis apoptosis uveal melanoma (UM) metastatic uveal melanoma (mUM) prognostication adjuvant therapy metastatic therapy metastatic dormancy liver-directed-therapies targeted-therapy combined therapy protein tyrosine phosphatase PTPs inhibitors melanoma immune infiltrate BRAF inhibitors microenvironment resistance therapy therapeutic resistance exosomes extracellular vesicles diagnosis prognosis ctDNA liquid biopsy prediction patient stratification BRAF arthralgia rheumatoid arthritis carbonic anhydrase hedgehog cyclopamine small molecules acetazolamide motility metalloproteinases FAK cancer mucosal melanoma nivolumab pembrolizumab ipilimumab radiotherapy cholinergic system acetylcholine muscarinic receptors nicotinic receptors melanoma metastasis ShcD adaptor protein amoeboid motility Rac1 DOCK4 melanoma PDX target therapy cancer stem cells slow cycling phenotype drug resistance OXPHOS lipid metabolism cancer associated fibroblast melanomagenesis biomarkers checkpoint inhibitor PD-1 melanoma markers cytokines machine learning Support Vector Machine principal component analysis BCL2L10 STAT3 cytotoxicity survival ABT-737 Bcl-2 family ML258 HuR MITF metastases siRNA |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557612103321 |
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Facchiano Antonio
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Advances in Lipidomics: Biomedicine, Nutrients and Methodology
| Advances in Lipidomics: Biomedicine, Nutrients and Methodology |
| Autore | Montero Olimpio |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 electronic resource (248 p.) |
| Soggetto topico | Research & information: general |
| Soggetto non controllato |
chronic kidney disease
leptin fatty acids adipose tissue adipocytes adipogenesis differential mobility spectrometry (DMS) lipidomics lipidyzer mass spectrometry metabolomics phenotyping Simpson-Golabi-Behmel syndrome (SGBS) COX CYP450 LOX oxylipins PUFAs UPLC-MS/MS copper Wilson’s disease lipidomic liquid chromatography tandem mass spectrometry molecular network dry eye disease hyperosmolarity cardiovascular disease heart failure myocardial infarction obesity diabetic cardiomyopathy dilated cardiomyopathy lipids odd chain lipids lipid profiling Folch protein precipitation sample preparation relative lipid composition (Mol%) atopic dermatitis SHARPIN-deficient mice flow-injection mass-spectrometry predictive elastic net immunotherapy cancer biomarkers metabolism cancer cell membranes fatty acid biosynthesis essential fatty acids desaturase enzymes fatty acid signaling fatty acid biomarker sapienic acid sebaleic acid molecular nutrition inflammation drug-induced liver injury biomarker plasma lipid profiles ssRNA+ virus membrane fusion lipid metabolism cholesterol sphingolipids phosphatidylinositol SARS-CoV glycolipidomics GIPC glycosyl inositol phospho ceramides Lipid Data Analyzer ultra-high pressure liquid chromatography high-resolution mass spectrometry LC-MS automated annotation |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | Advances in Lipidomics |
| Record Nr. | UNINA-9910557497303321 |
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Montero Olimpio
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Advances in Multiple Sclerosis Research-Series I
| Advances in Multiple Sclerosis Research-Series I |
| Autore | Matsoukas John |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 electronic resource (334 p.) |
| Soggetto topico | Medicine |
| Soggetto non controllato |
multiple sclerosis
inflammation oxidative biomarker sample size autoimmune encephalitis plasma exchange autoimmunity immunotherapeutics clinical outcomes major depression bupropion S-adenosylmethionine vitamin D3 yoga craniopharyngioma fractionated stereotactic radiation treatments sphenoid sinusitis cranial nerve-VI palsy autoimmune diseases immune thrombocytopenic purpura alemtuzumab antibodies against GluR3 peptide cognitive impairment diagnosis neuropsychological assessment short intracortical inhibition intracortical facilitation fampridine walking disability TSPAN32 tetraspanins cellular immunity memory T cells tDCS neuroimaging positron emission tomography cerebral blood flow probiotics Streptococcus thermophilus ST285 MBP83–99 peptide mannan immune modulation agonist peptide gut microbiome gut–brain axis metagenomics disease-modifying treatments MS vaccine immunomodulation carriers B cell receptor delivery methods immunotherapy monoclonal antibodies T cell receptor tolerance diagnostic markers immunoglobulins kappa free light chains antigen-specific immunotherapies tolerogenic vaccines tolerance induction central nervous system myelin peptides myelin basic protei proteolipid protein myelin oligodendrocyte glycoprotein nanotechnology drug delivery nanosystems lipids polymers vaccines nanoparticles antigen-specific immunotherapy experimental autoimmune encephalomyelitis neurodegeneration chloroquine EAE dendritic cells microglia astrocytes oligodendrocytes conformational analysis peptides altered peptide ligands NMR spectroscopy NOE-constraints molecular dynamic trimolecular complex Multiple Sclerosis early-onset adult-onset Human Leucocyte Antigens immunogenetics clinical phenotype clinical outcome therapeutics antibody detection ELISA multivalency N-glucosylated peptide epitopes peptide conjugation MOG35-55 Graphite/SiO2 electrode voltammetry HPLC MS drugs |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557385403321 |
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Matsoukas John
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Advances in Nanomaterials in Biomedicine
| Advances in Nanomaterials in Biomedicine |
| Autore | Ryabchikova Elena I |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 electronic resource (472 p.) |
| Soggetto topico | Medicine |
| Soggetto non controllato |
bone marrow-derived mesenchymal stromal cells
rAAV vectors carbon dots SOX9 TGF-β cartilage repair silver nanoparticles Entada spiralis Ceiba pentandra antibacterial assay catalytic dye reduction osteoarthritis human articular cartilage polymeric micelles pro-inflammatory cytokines IL-1β TNF-α nanomaterials nanomedicine immunotherapy oncotherapy immune-checkpoint inhibitors immunogenic cell death nano-vaccines nano-conjugates immune response oxidative stress antioxidants nanoparticles biological nano-antioxidants gold nanoparticles radiation chemotherapy radiosensitizer drug delivery system chemoradiotherapy magnetoliposomes hydrogels magnetolipogels self-assembly fluorescence Förster resonance energy transfer polypropylenimine dendrimers polyethylenimines tyrosine-modified polypropylene-imines tyrosine-modified polyethlyenimines PPI-Y siRNA transfection polymeric nanoparticles carbosilane dendron triazine amphiphile vesicles pH-sensitive doxorubicin methotrexate leukaemia molecular ultrasound nanobubbles active targeting targeted microbubbles angiogenesis inflammation thrombosis clinical translation molecular imaging liver fibrosis diagnosis therapy theranostics targeted drug delivery lipid conjugates amphiphilic oligonucleotides phosphoryl guanidines nucleic acid delivery leukemia iron nanoparticles RNA-Seq cytotoxicity polymers biodegradable drug delivery pharmaceutical SQUID magnetic properties iron content magnetite nanoparticles superoxide aorta heart nano-biomaterials nanotechnology scaffolds hard tissue engineering AuNPs AuPEI-NPs AuBSA-NPs electron microscopy ultrastructure of HepG2 cells and spheroids ultrastructure of HEK293 cells and spheroids penetration of NPs into monolayer and spheroids gold nanostars photothermal therapy photoacoustic imaging computed tomography cancer theranostic agents biocompatible nanomaterials diagnostics nanocarriers tissue engineering |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557724003321 |
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Ryabchikova Elena I
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Advances in the Treatment of Renal Cell Carcinoma
| Advances in the Treatment of Renal Cell Carcinoma |
| Autore | Reynolds Paul |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 electronic resource (221 p.) |
| Soggetto topico | Medicine |
| Soggetto non controllato |
renal cell carcinoma
autophagy hydroxychloroquine chloroquine ROC-325 cysteine cathepsins cysteine cathepsin inhibitors lysosome renal cancer metastatic renal cell carcinoma immune-based combination therapies network meta-analysis PD-L1 predictive biomarker treatment TKIs mRCC biomarkers soluble factors immunotherapy renal cell carcinoma (RCC) sunitib resistance artesunate (ART) Traditional Chinese Medicine (TCM) growth inhibition ferroptosis reactive oxygen species (ROS) clear cell renal cell carcinoma ccRCC RCC kidney cancer evolution evolutionary trajectory metastatic second line therapy renal cell cancer immune checkpoint inhibitors tyrosine kinase inhibitors individualization genomic signature transcriptomic analysis |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557615503321 |
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Reynolds Paul
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Anticancer Drugs 2021
| Anticancer Drugs 2021 |
| Autore | Meegan Mary J |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 electronic resource (594 p.) |
| Soggetto topico |
Research & information: general
Chemistry |
| Soggetto non controllato |
thymidylate synthase
cytotoxicity 1,2,3-triazole 1,3,4-oxadiazole 5-fluoruracil pemetrexed docking 3,4'-bis-guanidino 3-amino-4'-guanidino diphenyl ether phenyl pyridyl ether intramolecular hydrogen bond cancer cell viability HL-60 BRAF apoptosis thieno[2,3-d][1,2,3]triazine acetamide H1299 HER2 EGFR Bcl-2 inhibitors Indole-based analogues benzimidazole MTT cytotoxic assay cell cycle analysis DNA fragmentation ELISA solid/lipid nanoparticles phenstatin letrozole tubulin polymerisation inhibitor aromatase inhibitor breast cancer hybrid molecule dual-targeting molecule designed multiple ligand NaMSA cyclophosphamide histopathology testis urinary bladder anticancer agents enantioselective synthesis gastric adenocarcinoma tryptophanol concentration-guided dosing model informed dosing physiologically based pharmacokinetics sorafenib tyrosil-DNA-phosphodiesterase 1 adamantane resin acid TDP1 cytotoxic agents apoptosis induction HT-29 cells MDA-MB-231 cells mechanism prediction STAT inhibitors miR-21 hydrazide derivatives nitrogen scaffolds mitoxantrone cardiotoxicity inflammation oxidative stress age cumulative dose Trk NTRK tissue-agnostic larotrectinib entrectinib Trk fusion protein kinase inhibitors USFDA cancer patent review generic product doxazosin MD simulations combretastatin A-4 cytotoxic activity hybrid compounds indazole mucin MUC1 MUC16 immunotherapy cancer vaccine CAR (chimeric antigen receptor) ADC (antibody-drug conjugate) thiourea interleukin-6 trypan blue assay chalcones exportin-1 covalent binding CovDock anticancer activity xanthone in vitro in vivo isolation synthesis heterocyclic compound benzenesulfonamides imidazoles alkylated colony formation tumor spheroids HDAC inhibitors chalcone dual inhibitors carvedilol kidney toxicity 7-deaza-4'-thioadenosine derivatives multi-kinase inhibitor anticancer nucleoside Imiquimod drug efflux multidrug resistance Toll-Like Receptor |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910576874303321 |
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Meegan Mary J
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Application of Nanomaterials in Biomedical Imaging and Cancer Therapy
| Application of Nanomaterials in Biomedical Imaging and Cancer Therapy |
| Autore | Chow James C L |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 electronic resource (224 p.) |
| Soggetto topico |
Technology: general issues
History of engineering & technology |
| Soggetto non controllato |
nanoparticles
anisotropy plasmonic photothermal therapy surface plasmon resonance light scattering cancer treatment drug release microgels gold nanorods cancer therapy photothermal therapy photoacoustic imaging lung cancer EGFR-targeting nanoparticle cancer immunotherapy pH-responsive drug delivery application biomedical imaging correlative microscopy 3D CLEM volume imaging NIR-triggered photothermal agent deep tissue upconversion nanoparticles silica-coated UCNPs bio-imaging bio-application gold nanoparticles spiky nanoparticles phototheranostics colon cancer cells NIR triggering gold nanoparticle nanoparticle-enhanced radiotherapy MR-guided radiotherapy DNA damage Monte Carlo simulation dose enhancement magnetic field phototherapy photodynamic therapy Co-Fe ferrite nanoparticles magnetic hyperthermia specific loss power optimization alternative therapy |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910566461403321 |
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Chow James C L
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Bioinformatics and Machine Learning for Cancer Biology
| Bioinformatics and Machine Learning for Cancer Biology |
| Autore | Wan Shibiao |
| Pubbl/distr/stampa | Basel, : MDPI Books, 2022 |
| Descrizione fisica | 1 electronic resource (196 p.) |
| Soggetto topico |
Research & information: general
Biology, life sciences |
| Soggetto non controllato |
tumor mutational burden
DNA damage repair genes immunotherapy biomarker biomedical informatics breast cancer estrogen receptor alpha persistent organic pollutants drug-drug interaction networks molecular docking NGS ctDNA VAF liquid biopsy filtering variant calling DEGs diagnosis ovarian cancer PUS7 RMGs CPA4 bladder urothelial carcinoma immune cells T cell exhaustion checkpoint architectural distortion image processing depth-wise convolutional neural network mammography bladder cancer Annexin family survival analysis prognostic signature therapeutic target R Shiny application RNA-seq proteomics multi-omics analysis T-cell acute lymphoblastic leukemia CCLE sitagliptin thyroid cancer (THCA) papillary thyroid cancer (PTCa) thyroidectomy metastasis drug resistance biomarker identification transcriptomics machine learning prediction variable selection major histocompatibility complex bidirectional long short-term memory neural network deep learning cancer incidence mortality modeling forecasting Google Trends Romania ARIMA TBATS NNAR |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910595077403321 |
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Wan Shibiao
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| Basel, : MDPI Books, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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