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Advance in the Treatment of Pediatric Leukemia
| Advance in the Treatment of Pediatric Leukemia |
| Autore | Handgretinger Rupert |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 online resource (300 p.) |
| Soggetto topico |
Chemistry
Research & information: general |
| Soggetto non controllato |
5-azacitidine
ABCC4 acute lymphoblastic leukemia acute myeloid leukemia acute pancreatitis ADC advances ALL allogeneic stem cell transplantation alternative donors AML antibody antibody-drug conjugate B-ALL BCL11B BCP-ALL bispecific T-cell engager (BiTE) CD19 CFTR childhood acute lymphoblastic leukemia children chronic myeloid leukemia CML conditioning regimen COVID-19 diagnosis DUX4 evolution of CAR T cells Fc-engineering FDA-approved CAR products future directions of CAR T cell therapy genome hematopoietic stem cell transplantation IKZF1 immunizations immunotherapy juvenile myelomonocytic leukemia L-asparaginase leukemia limitations and complications of CAR T cell therapy low-risk ALL lymphoblastic leukemia minimal residual disease myelodysplastic/myeloproliferative disorders n/a NOTCH1 NUTM1 other extramedullary relapse PAX5 pediatric pediatric leukemia Ph-like polymorphism prognosis RAS signaling risk-stratified treatment SNV T-ALL targeted therapy TcR versus CAR TRAIL transcriptome treatment treatment related toxicity tyrosine kinase inhibitor xenograft ZNF384 |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910576878903321 |
Handgretinger Rupert
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Advanced Computational Methods for Oncological Image Analysis
| Advanced Computational Methods for Oncological Image Analysis |
| Autore | Rundo Leonardo |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 online resource (262 p.) |
| Soggetto topico | Medicine and Nursing |
| Soggetto non controllato |
3D-CNN
bone scintigraphy brain MRI image brain tumor brain tumor segmentation BRATS dataset breast cancer breast cancer detection breast cancer diagnosis breast imaging breast mass classification clutter rejection computer-aided detection contrast source inversion dataset partition deep learning dimensionality reduction ensemble classification ensemble method false positives reduction feature selection image reconstruction imaging biomarkers immunotherapy incoherent imaging interferometric optical fibers k-means clustering Kolmogorov-Smirnov hypothesis test machine learning magnetic resonance imaging mammography Mask R-CNN mass detection mass segmentation medical imaging melanoma detection microwave imaging MRgFUS n/a performance metrics principal component analysis prostate cancer proton resonance frequency shift radiomics RBF neural networks referenceless thermometry region growing risk assessment segmentation self-attention semisupervised classification shallow machine learning skull stripping statistical inference survey temperature variations texture transfer learning tumor region U-Net unsupervised machine learning Wisconsin Breast Cancer Dataset |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557353503321 |
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Rundo Leonardo
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Advances and Novel Treatment Options in Metastatic Melanoma
| Advances and Novel Treatment Options in Metastatic Melanoma |
| Autore | Facchiano Antonio |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 online resource (528 p.) |
| Soggetto topico | Medicine and Nursing |
| Soggetto non controllato |
ABT-737
acetazolamide acetylcholine adjuvant therapy amoeboid motility angiogenesis apoptosis arthralgia Bcl-2 family BCL2L10 biomarkers BRAF BRAF inhibitor BRAF inhibitors BRAF-mutant melanoma cancer cancer associated fibroblast cancer stem cells carbonic anhydrase cell therapy checkpoint inhibitor cholinergic system combined therapy ctDNA CXCL10 cyclopamine cytokines cytotoxicity diagnosis DOCK4 drug resistance essential oils exosomes extracellular vesicles FAK hedgehog HIPPO HuR immunity immunotherapy interferon invasion ipilimumab lactate dehydrogenase lipid metabolism liquid biopsy liver-directed-therapies machine learning MANS peptide MARCKS mechanism of action melanoma melanoma immune infiltrate melanoma markers melanoma metastasis melanoma PDX melanomagenesis metalloproteinases metastases metastasis metastatic dormancy metastatic therapy metastatic uveal melanoma (mUM) microenvironment microRNAs MITF ML258 motility mucosal melanoma muscarinic receptors n/a nanoparticles nicotinic receptors nivolumab OXPHOS patient stratification PD-1 pembrolizumab phosphorylation plasmacytoid dendritic cells prediction principal component analysis prognosis prognostication protein tyrosine phosphatase PTPs inhibitors Rac1 radiotherapy resistance rheumatoid arthritis sex-hormones sex/gender ShcD adaptor protein siRNA slow cycling phenotype small molecules SOCE STAT3 Support Vector Machine survival target therapy targeted therapy targeted-therapy therapeutic resistance therapy TLR TPC2 tumor microenvironment tumour microenvironment uveal melanoma (UM) WNT5A |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557612103321 |
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Facchiano Antonio
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Advances in Lipidomics: Biomedicine, Nutrients and Methodology
| Advances in Lipidomics: Biomedicine, Nutrients and Methodology |
| Autore | Montero Olimpio |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 online resource (248 p.) |
| Soggetto topico | Research & information: general |
| Soggetto non controllato |
adipocytes
adipogenesis adipose tissue atopic dermatitis automated annotation biomarker biomarkers cancer cancer cell membranes cardiovascular disease cholesterol chronic kidney disease copper COX CYP450 desaturase enzymes diabetic cardiomyopathy differential mobility spectrometry (DMS) dilated cardiomyopathy drug-induced liver injury dry eye disease essential fatty acids fatty acid biomarker fatty acid biosynthesis fatty acid signaling fatty acids flow-injection mass-spectrometry Folch GIPC glycolipidomics glycosyl inositol phospho ceramides heart failure high-resolution mass spectrometry hyperosmolarity immunotherapy inflammation LC-MS leptin Lipid Data Analyzer lipid metabolism lipid profiling lipidomic lipidomics lipids lipidyzer liquid chromatography LOX mass spectrometry membrane fusion metabolism metabolomics molecular network molecular nutrition myocardial infarction obesity odd chain lipids oxylipins phenotyping phosphatidylinositol plasma lipid profiles predictive elastic net protein precipitation PUFAs relative lipid composition (Mol%) sample preparation sapienic acid SARS-CoV sebaleic acid SHARPIN-deficient mice Simpson-Golabi-Behmel syndrome (SGBS) sphingolipids ssRNA+ virus tandem mass spectrometry ultra-high pressure liquid chromatography UPLC-MS/MS Wilson's disease |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | Advances in Lipidomics |
| Record Nr. | UNINA-9910557497303321 |
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Montero Olimpio
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Advances in Multiple Sclerosis Research-Series I
| Advances in Multiple Sclerosis Research-Series I |
| Autore | Matsoukas John |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 online resource (334 p.) |
| Soggetto topico | Medicine |
| Soggetto non controllato |
adult-onset
agonist peptide alemtuzumab altered peptide ligands antibodies against GluR3 peptide antibody detection antigen-specific immunotherapies antigen-specific immunotherapy astrocytes autoimmune diseases autoimmune encephalitis autoimmunity B cell receptor biomarker bupropion carriers cellular immunity central nervous system cerebral blood flow chloroquine clinical outcome clinical outcomes clinical phenotype cognitive impairment conformational analysis conjugation cranial nerve-VI palsy craniopharyngioma delivery methods dendritic cells diagnosis diagnostic markers disease-modifying treatments drug delivery nanosystems EAE early-onset ELISA experimental autoimmune encephalomyelitis fampridine fractionated stereotactic radiation treatments free light chains Graphite/SiO2 electrode gut microbiome gut-brain axis HPLC Human Leucocyte Antigens immune modulation immune thrombocytopenic purpura immunogenetics immunoglobulins immunomodulation immunotherapeutics immunotherapy inflammation intracortical facilitation kappa lipids major depression mannan MBP83-99 peptide memory T cells metagenomics microglia MOG35-55 molecular dynamic monoclonal antibodies MS MS drugs multiple sclerosis Multiple Sclerosis multivalency myelin basic protei myelin oligodendrocyte glycoprotein myelin peptides N-glucosylated peptide epitopes nanoparticles nanotechnology neurodegeneration neuroimaging neuropsychological assessment NMR spectroscopy NOE-constraints oligodendrocytes oxidative peptide peptides plasma exchange polymers positron emission tomography probiotics proteolipid protein S-adenosylmethionine sample size short intracortical inhibition sphenoid sinusitis ST285 Streptococcus thermophilus T cell receptor tDCS tetraspanins therapeutics tolerance tolerance induction tolerogenic vaccines trimolecular complex TSPAN32 vaccine vaccines vitamin D3 voltammetry walking disability yoga |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557385403321 |
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Matsoukas John
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Advances in Nanomaterials in Biomedicine
| Advances in Nanomaterials in Biomedicine |
| Autore | Ryabchikova Elena I |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 online resource (472 p.) |
| Soggetto topico | Medicine |
| Soggetto non controllato |
active targeting
amphiphile amphiphilic oligonucleotides angiogenesis antibacterial assay antioxidants aorta AuBSA-NPs AuNPs AuPEI-NPs biocompatible nanomaterials biodegradable biological nano-antioxidants bone marrow-derived mesenchymal stromal cells cancer carbon dots carbosilane cartilage repair catalytic dye reduction Ceiba pentandra chemoradiotherapy chemotherapy clinical translation computed tomography cytotoxicity dendron diagnosis diagnostics doxorubicin drug delivery drug delivery system electron microscopy Entada spiralis fluorescence Förster resonance energy transfer gold nanoparticles gold nanostars hard tissue engineering heart human articular cartilage hydrogels IL-1β immune response immune-checkpoint inhibitors immunogenic cell death immunotherapy inflammation iron content iron nanoparticles leukaemia leukemia lipid conjugates liver fibrosis magnetic properties magnetite nanoparticles magnetolipogels magnetoliposomes methotrexate molecular imaging molecular ultrasound nano-biomaterials nano-conjugates nano-vaccines nanobubbles nanocarriers nanomaterials nanomedicine nanoparticles nanotechnology nucleic acid delivery oncotherapy osteoarthritis oxidative stress penetration of NPs into monolayer and spheroids pH-sensitive pharmaceutical phosphoryl guanidines photoacoustic imaging photothermal therapy polyethylenimines polymeric micelles polymeric nanoparticles polymers polypropylenimine dendrimers PPI-Y pro-inflammatory cytokines rAAV vectors radiation radiosensitizer RNA-Seq scaffolds self-assembly silver nanoparticles siRNA transfection SOX9 SQUID superoxide targeted drug delivery targeted microbubbles TGF-β theranostic agents theranostics therapy thrombosis tissue engineering TNF-α triazine tyrosine-modified polyethlyenimines tyrosine-modified polypropylene-imines ultrastructure of HEK293 cells and spheroids ultrastructure of HepG2 cells and spheroids vesicles |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557724003321 |
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Ryabchikova Elena I
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Advances in the Treatment of Renal Cell Carcinoma
| Advances in the Treatment of Renal Cell Carcinoma |
| Autore | Reynolds Paul |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 online resource (221 p.) |
| Soggetto topico | Medicine |
| Soggetto non controllato |
artesunate (ART)
autophagy biomarker biomarkers ccRCC chloroquine clear cell renal cell carcinoma cysteine cathepsin inhibitors cysteine cathepsins evolution evolutionary trajectory ferroptosis genomic signature growth inhibition hydroxychloroquine immune checkpoint inhibitors immune-based combination therapies immunotherapy individualization kidney cancer lysosome metastatic metastatic renal cell carcinoma mRCC network meta-analysis PD-L1 predictive RCC reactive oxygen species (ROS) renal cancer renal cell cancer renal cell carcinoma renal cell carcinoma (RCC) ROC-325 second line therapy soluble factors sunitib resistance TKIs Traditional Chinese Medicine (TCM) transcriptomic analysis treatment tyrosine kinase inhibitors |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557615503321 |
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Reynolds Paul
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Anticancer Drugs 2021
| Anticancer Drugs 2021 |
| Autore | Meegan Mary J |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 online resource (594 p.) |
| Soggetto topico |
Chemistry
Research & information: general |
| Soggetto non controllato |
1,2,3-triazole
1,3,4-oxadiazole 3-amino-4'-guanidino 3,4'-bis-guanidino 5-fluoruracil 7-deaza-4'-thioadenosine derivatives acetamide adamantane ADC (antibody-drug conjugate) age alkylated anticancer anticancer activity anticancer agents apoptosis apoptosis induction aromatase inhibitor Bcl-2 inhibitors benzenesulfonamides benzimidazole BRAF breast cancer cancer cancer cell viability cancer vaccine CAR (chimeric antigen receptor) cardiotoxicity carvedilol cell cycle analysis chalcone chalcones colony formation combretastatin A-4 concentration-guided dosing covalent binding CovDock cumulative dose cyclophosphamide cytotoxic activity cytotoxic agents cytotoxicity designed multiple ligand diphenyl ether DNA fragmentation docking doxazosin drug efflux dual inhibitors dual-targeting molecule EGFR ELISA enantioselective synthesis entrectinib exportin-1 gastric adenocarcinoma generic product H1299 HDAC inhibitors HER2 heterocyclic compound histopathology HL-60 HT-29 cells hybrid compounds hybrid molecule hydrazide derivatives imidazoles Imiquimod immunotherapy in vitro in vivo indazole Indole-based analogues inflammation interleukin-6 intramolecular hydrogen bond isolation kidney larotrectinib letrozole MD simulations MDA-MB-231 cells mechanism prediction miR-21 mitoxantrone model informed dosing MTT cytotoxic assay MUC1 MUC16 mucin multi-kinase inhibitor multidrug resistance n/a NaMSA nitrogen scaffolds NTRK nucleoside oxidative stress patent review pemetrexed phenstatin phenyl pyridyl ether physiologically based pharmacokinetics protein kinase inhibitors resin acid solid/lipid nanoparticles sorafenib STAT inhibitors synthesis TDP1 testis thieno[2,3-d][1,2,3]triazine thiourea thymidylate synthase tissue-agnostic Toll-Like Receptor toxicity Trk Trk fusion trypan blue assay tryptophanol tubulin polymerisation inhibitor tumor spheroids tyrosil-DNA-phosphodiesterase 1 urinary bladder USFDA xanthone |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910576874303321 |
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Meegan Mary J
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Application of Nanomaterials in Biomedical Imaging and Cancer Therapy
| Application of Nanomaterials in Biomedical Imaging and Cancer Therapy |
| Autore | Chow James C L |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 online resource (224 p.) |
| Soggetto topico |
History of engineering & technology
Technology: general issues |
| Soggetto non controllato |
3D CLEM
alternative therapy anisotropy application bio-application bio-imaging biomedical imaging cancer cancer therapy cancer treatment Co-Fe ferrite nanoparticles colon cancer cells correlative microscopy deep tissue DNA damage dose enhancement drug delivery drug release EGFR-targeting gold nanoparticle gold nanoparticles gold nanorods immunotherapy light scattering lung cancer magnetic field magnetic hyperthermia microgels Monte Carlo simulation MR-guided radiotherapy n/a nanoparticle nanoparticle-enhanced radiotherapy nanoparticles NIR triggering NIR-triggered optimization pH-responsive photoacoustic imaging photodynamic therapy phototheranostics phototherapy photothermal agent photothermal therapy plasmonic photothermal therapy silica-coated UCNPs specific loss power spiky nanoparticles surface plasmon resonance upconversion nanoparticles volume imaging |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910566461403321 |
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Chow James C L
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Bioinformatics and Machine Learning for Cancer Biology
| Bioinformatics and Machine Learning for Cancer Biology |
| Autore | Wan Shibiao |
| Pubbl/distr/stampa | Basel, : MDPI Books, 2022 |
| Descrizione fisica | 1 electronic resource (196 p.) |
| Soggetto topico |
Research & information: general
Biology, life sciences |
| Soggetto non controllato |
tumor mutational burden
DNA damage repair genes immunotherapy biomarker biomedical informatics breast cancer estrogen receptor alpha persistent organic pollutants drug-drug interaction networks molecular docking NGS ctDNA VAF liquid biopsy filtering variant calling DEGs diagnosis ovarian cancer PUS7 RMGs CPA4 bladder urothelial carcinoma immune cells T cell exhaustion checkpoint architectural distortion image processing depth-wise convolutional neural network mammography bladder cancer Annexin family survival analysis prognostic signature therapeutic target R Shiny application RNA-seq proteomics multi-omics analysis T-cell acute lymphoblastic leukemia CCLE sitagliptin thyroid cancer (THCA) papillary thyroid cancer (PTCa) thyroidectomy metastasis drug resistance biomarker identification transcriptomics machine learning prediction variable selection major histocompatibility complex bidirectional long short-term memory neural network deep learning cancer incidence mortality modeling forecasting Google Trends Romania ARIMA TBATS NNAR |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910595077403321 |
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Wan Shibiao
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| Basel, : MDPI Books, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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