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Approaches to Advance Cancer Vaccines to Clinical Utility
| Approaches to Advance Cancer Vaccines to Clinical Utility |
| Autore | Van Nuffel An M. T |
| Pubbl/distr/stampa | Frontiers Media SA, 2019 |
| Descrizione fisica | 1 electronic resource (196 p.) |
| Soggetto topico |
Medicine
Immunology |
| Soggetto non controllato |
cancer vaccines
personalized adjuvant antigen-presenting cell in situ vaccination immunosuppression biomarkers |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557547503321 |
Van Nuffel An M. T
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| Frontiers Media SA, 2019 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Biomarkers of Renal Diseases
| Biomarkers of Renal Diseases |
| Autore | García-Estañ Joaquín |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 electronic resource (276 p.) |
| Soggetto topico | Medicine |
| Soggetto non controllato |
poststreptococcal acute glomerulonephritis
infection-related glomerulonephritis nephritis-associated plasmin receptor plasmin acute kidney injury renal biomarkers furosemide stress test functional assessment urine diabetic kidney disease kidney function proteomics mass spectrometry statistical clinical model machine learning acute tubulointerstitial nephritis immunology biomarkers chronic kidney disease differential diagnosis label-free quantification renal transplant extracellular vesicles acute rejection chronic rejection chronic allograft dysfunction calcineurin-inhibitor nephrotoxicity Polyomavirus associated nephropathy immunosuppression upper urinary tract obstruction kidney injury neutrophil gelatinase-associated lipocalin monocyte chemotactic protein-1 kidney injury molecule 1 cystatin C vanin-1 microRNA uromodulin kidney graft function biomarker kidney transplantation long noncoding RNA rejection microvascular injury urinary aminopeptidases arterial hypertension renal function urinary biomarkers markers of AKI cystatin-C NGAL KIM-1 exercise end-stage kidney disease (ESKD) cardiovascular disease epidemiology CKD macrophage subpopulation renal fibrosis trichostatin A kidney graft T-cell-mediated rejection antibody-mediated rejection diagnostic test accuracy gentamicin sepsis miRNA nephrotoxicity vancomycin |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557493003321 |
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García-Estañ Joaquín
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Bovine Viral Diarrhea Virus and Related Pestiviruses
| Bovine Viral Diarrhea Virus and Related Pestiviruses |
| Autore | Bielefeldt-Ohmann Helle |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 |
| Descrizione fisica | 1 electronic resource (290 p.) |
| Soggetto topico |
Research & information: general
Biology, life sciences |
| Soggetto non controllato |
Linda virus
serological profile virus neutralization assay virus pathogenicity humoral immune response pestivirus pig APPV phylogenetic analysis Italy bvdv epidemiology reindeer border disease virus Norway Pestivirus BVDV CD46 life cell imaging attachment surface transport experimental infection natural infection pigs bovine viral diarrhoea virus persistent testicular infection prolonged testicular infection bovine testes semen wild boar ML tree Clade Bungowannah virus pestivirus F ruminant infection foetus porcine real-time PCR serology virology bovine viral diarrhea virus cytopathic BVDV immunosuppression lymphocyte apoptosis monocyte-derived macrophages non-cytopathic BVDV Australia deer prevalence ruminants serosurveillance wildlife disease diarrhea bovine respiratory disease milk production somatic cells count (SCC) reproductive performance BVDV persistent infection fetus thymus immune response flavivirus reverse genetics single round infectious particle bovine viral diarrhea virus (BVDV) escape mutant ERNS adaptation CRISPR knockout MDBK cell entry pestiviruses congenital tremor type A-II persistent infection rangeland beef herds northern Australia atypical porcine pestivirus (APPV) viral persistence congenital tremor swine asymptomatic genomic sequence purifying selection bovine pestiviruses bovine viral diarrhoea vaccination control diagnosis antigenic cross-reactivity |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557301103321 |
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Bielefeldt-Ohmann Helle
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Cancer Immunology
| Cancer Immunology |
| Autore | Subramanian Subree |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 electronic resource (316 p.) |
| Soggetto topico | Medicine |
| Soggetto non controllato |
NKG2D
CAR T IL-7 prostate cancer cell therapy CD19-CAR-T B cell aplasia KIR PD-1 inhibitory CAR tumor-infiltrating lymphocytes tumor microenvironment immunotherapy NK cells cancer stem cells (CSCs) antibody-dependent cellular cytotoxicity (ADCC) differentiation cytotoxicity IFN-γ osteoclasts MICA/B mAb DNA methylation RNA methylation S-adenosylmethionine (SAM) cancer innate immunity adaptive immunity T cells m6A PD-L1 resistance immune checkpoints cancer vaccine combination immunotherapy TCR diversity organ transplantation carcinoma epidemiologic studies immunosuppression CTLA-4 Treg cells immune checkpoint inhibitors CD28 antigen-presenting cells IL15 colon cancer melanoma uveal BAP1 anti-PD-1 anti-CTLA-4 TIL classical and endemic Kaposi Sarcoma systemic treatment multi-state modelling treatment free interval chemotherapy interferon triple negative breast cancer immunomodulation bispecific antibody sortase A chemo-enzymatic approach anti-CD20 antibody Fab BiFab colorectal cancer dendritic cells Atypical Chemokine Receptor 4 (ACKR4) T-cell priming immune checkpoint blockade primary liver cancer kynurenine pathway immune evasion indoleamine 2,3 dioxygenase 1 tryptophan 2,3 dioxygenase 2 IDO inhibitor antigen presenting cells |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557349203321 |
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Subramanian Subree
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Cancer Nanomedicine
| Cancer Nanomedicine |
| Autore | Hoskins Clare |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 |
| Descrizione fisica | 1 electronic resource (510 p.) |
| Soggetto topico | Technology: general issues |
| Soggetto non controllato |
antibody drug conjugate (ADC)
PD-L1 tumor spheroid disruption immune modulation doxorubicin graphene oxide adsorption cathepsin D cathepsin L anti-metastatic enzyme cancer therapy nanoparticles targeted delivery system siRNA osteopontin mammary carcinoma mesenchymal stem cells (MSCs) TAT peptide PLGA paclitaxel nano-engineered MSCs orthotopic lung tumor model intracranial glioma immunotherapy CPMV viral nanoparticles in situ vaccine albumin nanoparticles microbubble ultrasound theranostics hepatocellular carcinoma VX2 tumor intra-arterial chemotherapy lung cancer nanomedicine clinical status cancer therapy breast cancer cell signaling active targeting passive targeting EPR effect oncogenes nanoparticle drug delivery ligand tumor targeting biodistribution Mesoporous silica nanoparticle drug delivery system target treatment lanthanide metal hyaluronic acid hyaluronidase drug combination everolimus dual-targeting magnetic nanoparticles monoclonal antibodies nanostructured lipid carrier platelet membrane biomimicry plasmonic photothermal therapy gold nanorods surgery bleeding dogs cats stimuli-responsive DOX SN38 CSCs single-walled carbon nanotubes chirality separation NASH drug-gene delivery near IR hyperspectral imaging plasmonics copper VEGF glioblastoma differentiated neuroblastoma peptidomimetics real-time quantitative polymerase chain reaction (qPCR) actin combinatorial therapy anticancer and antibacterial activity temoporfin drug-in-cyclodextrin-in-liposome hybrid nanoparticles multicellular tumor spheroids cyclodextrins photodynamic therapy article yet reasonably common within the subject discipline antitumor strategy biomimetic core–shell nanoparticles NK cell-derived exosomes folate receptor albumin nanoparticle microfluidic cabazitaxel polydopamine nanoparticles size cytotoxicity iron affinity FA-DABA-SMA self-assembly oncogenic proteins intracellular disruption folic receptor alpha pancreatic cancer parvifloron D albumin erlotinib photodynamic therapy lipid nanoparticles tumor vectorization verteporfin ovarian carcinomatosis spheroids integrin RGD peptide cancer diagnosis radiotherapy hyperthermia therapy biomimetic nanocarrier membrane-wrapped cancer targeted delivery photothermal therapy imaging cancer nanomedicine tumor microenvironment nano–bio interactions clinical translation magnetic nanowires magnetic hyperthermia magnetic actuation magnetic drug targeting titanate nanotubes gold nanoparticles vectorization colloidal stability docetaxel prostate cancer mangiferin anti-topoisomerase activity extracellular vesicles exosomes chemico-physical functionalization loading translational medicine nanotechnology: bioengineering anacardic acid mitoxantrone targeted drug delivery liposomes melanoma apoptosis ascorbic acid angiogenesis epithelial-to-mesenchymal transition hypoxia immunosuppression metabolism nanotherapeutics tumour microenvironment DNA origami liposome remote loading acute toxicity organoids magnetic silica-coated iron oxide nanochains photothermal treatment hyperthermia collagen cellular microenvironment lymphadenectomy magnetometer sentinel lymph node dissection SPION superparamagnetic iron oxide nanoparticles Vδ2 T cells zoledronic acid polymeric nanoconstruct anti-tumor immunity colorectal carcinoma β-cyclodextrin nanosponges BALB-neuT mice brain tumours glioma blood brain barrier polymeric nanoparticles PEGylation dioleoylphosphatidylethanolamine poly(hydroxyethyl acrylate-co-allyl methyl sulfide) copolymer folate oxidation-sensitive release cellular interaction in vitro anti-cancer activity triple negative breast cancer organotin mesoporous silica nanoparticles MDA-MB-231 theranostic nanomaterials nanobiotechnology molecular imaging nanosystems nanomicelles ovarian cancer tumour targeting chemotherapeutics riboflavin vitamin B2 nanomedicines secondary structure mixed micelle pH responsive targeted therapy anti-cancer shear stress flow in vitro therapeutics diagnostics Immunotherapy |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557114703321 |
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Hoskins Clare
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Clinical Studies, Big Data, and Artificial Intelligence in Nephrology and Transplantation
| Clinical Studies, Big Data, and Artificial Intelligence in Nephrology and Transplantation |
| Autore | Cheungpasitporn Wisit |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 electronic resource (374 p.) |
| Soggetto topico | Medicine |
| Soggetto non controllato |
tacrolimus
C/D ratio tacrolimus metabolism everolimus conversion kidney transplantation gut microbiome renal transplant recipient diarrhea immunosuppressive medication gut microbiota 16S rRNA sequencing butyrate-producing bacteria Proteobacteria torquetenovirus immunosuppression transplantation immunosuppressed host outcome renal transplantation Goodpasture syndrome anti-GBM disease epidemiology hospitalization outcomes acute kidney injury risk prediction artificial intelligence patent ductus arteriosus conservative management blood pressure eradication interferon-free regimen hepatitis C infection kidney transplant allograft steatosis lipopeliosis transplant numbers live donors public awareness Google TrendsTM machine learning big data nephrology chronic kidney disease NLR PLR RPGN predictive value hemodialysis withdrawal cellular crescent global sclerosis procurement kidney biopsy glomerulosclerosis minimally-invasive donor nephrectomy robot-assisted surgery laparoscopic surgery organ donation living kidney donation MeltDose® LCPT renal function liver transplantation metabolism erythropoietin fibroblast growth factor 23 death weekend effect in-hospital mortality comorbidity dialysis elderly klotho α-Klotho FGF-23 kidney donor Nephrology CKD-MBD CKD-Mineral and Bone Disorder deceased donor Eurotransplant Senior Program risk stratification intensive care kidney transplant recipients long-term outcomes graft failure cardiovascular mortality lifestyle inflammation vascular calcification bone mineral density dual-energy X-ray absorptiometry living donation repeated kidney transplantation graft survival prolonged ischaemic time patient survival pre-emptive transplantation metabolomics urine acute rejection allograft cystatin C hyperfiltration kidney injury molecule (KIM)-1 tubular damage genetic polymorphisms (cardiac) surgery inflammatory cytokines clinical studies chronic kidney disease (CKD) no known kidney disease (NKD) ICD-10 billing codes phenotyping electronic health record (EHR) estimated glomerular filtration rate (eGFR) machine learning (ML) generalized linear model network (GLMnet) random forest (RF) artificial neural network (ANN), clinical natural language processing (clinical NLP) discharge summaries laboratory values area under the receiver operating characteristic (AUROC) area under the precision-recall curve (AUCPR) fibrosis extracellular matrix collagen type VI living-donor kidney transplantation ethnic disparity |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557367503321 |
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Cheungpasitporn Wisit
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Enhancing Mesenchymal Stem Cells (MSCs) for Therapeutic Purposes
| Enhancing Mesenchymal Stem Cells (MSCs) for Therapeutic Purposes |
| Autore | Ylostalo Joni H |
| Pubbl/distr/stampa | Basel, : MDPI Books, 2022 |
| Descrizione fisica | 1 electronic resource (204 p.) |
| Soggetto topico | Medicine |
| Soggetto non controllato |
cell therapy
immunomodulation polyunsaturated fatty acid CD206 phagocytosis mesenchymal stem cells Vadadustat AKB-6548 preconditioning priming secretome chemotaxis Wharton’s jelly mesenchymal stem cells umbilical cord oxygen conditions secretory profile neuroprotection mesenchymal stromal cells 3D culture neurospheres spheroids pluripotency neural quiescence mesothelioma malignant pleural mesothelioma (MPM) liver cirrhosis placenta-derived mesenchymal stem cells WKYMVm combination therapy iPSC-derived MSCs iMSC secretome pre-conditioning angiogenesis IFN-γ hypoxia potentiation of iMSC efficacy nanofiber-hydrogel composite spinal cord injury inflammation macrophages secondary injury astrocytes axon growth adipose tissue-derived stem cells (ASCs) autophagy rapamycin 3-methyladenine immunosuppression exosome engineered cardiac patches adipose-derived stem cell paracrine potential osteogenic differentiation hepatocyte growth factor fibroblast growth factor 2 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | Enhancing Mesenchymal Stem Cells |
| Record Nr. | UNINA-9910595079403321 |
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Ylostalo Joni H
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| Basel, : MDPI Books, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Mechanisms and Novel Therapeutic Approaches for Gynecologic Cancer
| Mechanisms and Novel Therapeutic Approaches for Gynecologic Cancer |
| Autore | Nakayama Naomi |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 electronic resource (258 p.) |
| Soggetto topico | Public health & preventive medicine |
| Soggetto non controllato |
nucleus accumbens-associated protein 1 (NAC1)
BEN (BANP, E5R and NAC1) domain sequence-specific DNA-binding protein solution NMR structure isothermal titration calorimetry (ITC) human cytomegalovirus ovarian cancer cancer progression inflammation immunosuppression endometrial carcinoma immune micro-environment immune checkpoints inhibitors microsatellite instability mismatch repair deficiency platelet-activating factor acetylhydrolase (PAF-AH PLA2G7) BRCA1 mutant ovarian cancer Wnt signaling pGSK3β β-catenin prognosis vulvar melanoma vaginal melanoma targeted therapy gynecological cancer melanoma treatment gene ontology epithelial ovarian cancers borderline ovarian tumors differentially expressed genes aryl hydrocarbon receptor epithelial-mesenchymal transition integrative analysis testin p16 protein cervical cancer cervical neoplasia immunohistochemistry chimeric antigen receptor CD44 adoptive immunotherapy NK cells epithelial ovarian cancer DNA damage response somatic mutation clear cell carcinoma endometrioid endometrial cancer DNA mismatch repair (MMR) MMR deficient (dMMR) long-term survival exosome miRNA biomarkers liquid biopsy interventional radiotherapy vaginal-cuff brachytherapy HDR brachytherapy in vivo dosimetry endometrial cancer biological planning drug repurposing non-coding RNAs nanocarriers anti-angiogenic therapy |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910580209103321 |
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Nakayama Naomi
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Personalized Medicine in the Field of Inflammatory Skin Disorders
| Personalized Medicine in the Field of Inflammatory Skin Disorders |
| Autore | Tampa Mircea |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 electronic resource (262 p.) |
| Soggetto topico | Medicine |
| Soggetto non controllato |
sea-buckthorn seed oil
long-chain fatty acids skin dysplastic keratinocytes UVA CD36 SR-B2 atopic dermatitis eczema JAK inhibitors systematic review meta-analysis evidence-based medicine immune-mediated skin diseases target therapy skin conditions and systemic inflammatory diseases systemic sclerosis biomarker calumenin S100A6 cytohesin 2 cannabinoids inflammation gut-lung-skin barrier signaling pathways inflammatory biomarkers psoriasis vulgaris prevalence comorbidities risk factors systemic lupus erythematous lupus nephritis lipid peroxidation DNA oxidation oxidized proteins carbohydrate oxidation antioxidative stress strategies biomarkers IgY psoriatic dermatitis imiquimod C57 BL/6 mice alginate biomaterial dressing fibers hydrogel nanofibers commercially available wound care wound healing cutaneous melanoma epigenetic regulation drug resistance therapeutic targets epigenetic therapy immune response Sutton nevi halo nevi skin tumor psoriasis proteome analysis estrogen menopause cSCC AK sialylation sialyltransferase sialidase COVID-19 pyoderma gangrenosum immunosuppression cyclosporine corticosteroids autoinflammatory disease androgenic alopecia clinical trial hair density platelet-rich plasma |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910566475103321 |
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Tampa Mircea
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Progress and Recent Advances in Solid Organ Transplantation
| Progress and Recent Advances in Solid Organ Transplantation |
| Autore | Thongprayoon Charat |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 electronic resource (188 p.) |
| Soggetto topico |
Medicine
Pharmacology |
| Soggetto non controllato |
living donation
nephrectomy hand-assisted laparoscopic nephrectomy body composition complications simultaneous pancreas-kidney transplantation immunosuppression graft order sequence outcome survival kidney transplantation hydrogen diarrhea small intestinal bacterial overgrowth sickle cell disease sickle cell transplantation outcomes big data tacrolimus metabolism C/D ratio cholesterol dyslipidemia LDL-C liver transplantation hematuria chronic kidney disease tocilizumab clazakizumab desensitization anti-HLA alloantibody post traumatic growth psychiatric morbidity network analysis ESAS MINI CPC DCPR distress demoralization alexithymia anxiety antibody-mediated rejection recurrent primary disease renal transplantation pancreas transplantation cold ischemia time delayed graft function Eurotransplant Senior Program end-stage renal disease intensive care unit bioimpedance analysis drug dosing lean body mass index pharmacokinetics tacrolimus C/D ratio mineral bone disorder parathyroidectomy parathyroid hormone osteoporosis bone fractures Contrast-enhanced ultrasound kidney perfusion kidney function kidney donation |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910576885203321 |
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Thongprayoon Charat
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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