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Aging and Age-related Disorders: From Molecular Mechanisms to Therapies
| Aging and Age-related Disorders: From Molecular Mechanisms to Therapies |
| Autore | Titorenko Vladimir |
| Pubbl/distr/stampa | MDPI - Multidisciplinary Digital Publishing Institute, 2019 |
| Descrizione fisica | 1 electronic resource (322 p.) |
| Soggetto non controllato |
advanced glycated end products
microRNAs differentiation transcription skin absorption cellular quiescence lifespan longevity genes protein kinases self-renewal circadian blood-brain barrier aging-related disorders sirtuin-1 inflammation arterial aging reactive oxygen species electron microscopy reconstructed human skin rejuvenation low-dose fluvastatin and valsartan combination inflammaging hematopoietic stem cell aging cell cycle mitochondria ribose the nervous system nanomedicine proteostasis adult stem cells immunosenescence cell signaling mechanisms of quiescence maintenance metabolism aging melatonin diabetes mechanisms of quiescence entry and exit Drosophila melanogaster GSK3 (glycogen synthase kinase 3) |
| ISBN | 3-03921-356-3 |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | Aging and Age-related Disorders |
| Record Nr. | UNINA-9910367567903321 |
Titorenko Vladimir
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| MDPI - Multidisciplinary Digital Publishing Institute, 2019 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Cellular Oxidative Stress
| Cellular Oxidative Stress |
| Autore | Marino Angela |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 electronic resource (529 p.) |
| Soggetto topico | Medicine |
| Soggetto non controllato |
neuroinflammation
clinical palmitoylethanolamide luteolin co-ultramicronization CNS pathology adaptive immune response cell homeostasis legumes liver hepatic steatosis lipid dyshomeostasis ROS traumatic brain injury palmitoylethanolamide (PEA) therapeutic strategies oxidative stress RNA-Seq RPE Retinitis pigmentosa A2E diabetes glucose exposure Band 3 protein erythrocytes SO42− 4-hydroxy-2-nonenal 3-glutathionyl-4-hydroxynonanal astrocytoma cells soy soybeans soy foods antioxidants reactive oxygen species cardiovascular diseases cancer paw edema cashew nuts antioxidant inflammation polyphenols analgesic d-Galactose glycation SO42− uptake anion exchange diseases immune system NF-κB cigarette smoke extract nasal fibroblasts tissue inhibitor of metalloproteinases matrix metalloproteinase steroids Plasmodium falciparum syk kinase inhibitors artemisinin derivatives hemichromes cellular redox state mitochondrial function cisplatin nephrotoxicity acute pancreatitis obesity nitrosative stress PGC-1α microparticles vesiculation band 3 tert-Bytyl hydroperoxide t-BOOH nitric oxide donor calcium ionophore A23187 age-related macular degeneration (AMD) diet Substance-P adipose-derived stem cells paracrine factors epilepsy status epilepticus Trolox HeLa prooxidant AVD apoptosis neurodegeneration ncRNA miRNA tRNA fragments lncRNA circRNA preeclampsia hemostasis platelets coagulation fish mucosal immunity nasal immunity peroxide vitamin C NAC immunosenescence T cells vaccination aging microvascular permeability bradykinin interleukin 1β NADPH oxidase simvastatin molecular hydrogen autophagy matrix metalloproteinases reactive oxygen species (ROS) phytochemicals dietary chemicals natural compounds programmed cell death anoikis ferroptosis pyroptosis |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557338703321 |
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Marino Angela
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Centenarians-A Model to Study the Molecular Basis of Lifespan and Healthspan
| Centenarians-A Model to Study the Molecular Basis of Lifespan and Healthspan |
| Autore | Puca Annibale |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 electronic resource (204 p.) |
| Soggetto topico |
Research & information: general
Biology, life sciences |
| Soggetto non controllato |
aging
alternative therapy composition of royal jelly dietary interventions healthspan lifespan longevity royal jelly IGF-1 oxidative stress ageing nematode immunosenescence probiotic bacteria pathogen protection food allergy elderly hypersensitivity gut allergy inflammation redoxomics glutathione meniere's disease neurodegenerative diseases healthy aging DNA methylation epigenetic clocks telomere length centenarians exosomes serum functional enrichment analysis ingenuity pathway analysis miRNA-mRNA networks aging-related disease Di (2-Ethylhexyl) pthalate Hericium erinaceus vitagenes apoptosis mitochondrial respiratory complexes C. elegans polyphenols olive oil Parkinson's disease β-Dystroglycan cellular senescence lamin B1 DNA-damage response defective mitosis |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557783503321 |
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Puca Annibale
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Diet and Immune Function
| Diet and Immune Function |
| Autore | Childs Caroline E |
| Pubbl/distr/stampa | MDPI - Multidisciplinary Digital Publishing Institute, 2020 |
| Descrizione fisica | 1 electronic resource (314 p.) |
| Soggetto non controllato |
immunonutrition
supplementation superoxide dismutase (SOD) fermented milk selenocysteine dendritic cells lipoxygenase (LOX) chronic inflammatory conditions formulation immune system cytokines skeletal muscle zinc non-digestible carbohydrates Toll-like receptor carbohydrates fiber lymphocytes antibody infants liver macrophage inflammatory process probiotic plant older people gut barrier infection amino acids gut T helper 1 (Th1) immunity T cells bioactive peptide inhibitor of kappa kinase (IKK) inflammation adhesion molecules leukocytes human milk oligosaccharides vitamin D food structure vitamin E mitogen-activated protein Kinase (MAPK) gut microbiota weaning homeostasis intestinal immune system extra-cellular signal regulated kinases (ERK) cyclooxygenase (COX) oxidative stress life course polyphenols oligosaccharides micronutrients Th17 obesity tolerance arachidonic acid growth factors anti-inflammation age-related immunity prebiotic biomarker microbiome functional foods immunosenescence nutrition molecular mechanisms metabolism macronutrients toll-like receptor 4 sepsis nutrition guidelines microbiota immunomodulation inflammatory markers elderly Th1/Th17 response adults reactive oxygen species (ROS) anorexia nervosa macrophages autoimmune diseases fatty acids T cell Treg breast milk nitric oxide synthase (NOS) chemokines anti-tumorigenic metabolites deficiency protein hydrolysate nuclear factor kappa-light-chain-enhancer of activated B cells (NF-?B) cancer |
| ISBN | 3-03921-613-9 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910404080503321 |
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Childs Caroline E
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| MDPI - Multidisciplinary Digital Publishing Institute, 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Mitochondrial Dysfunction in Aging and Diseases of Aging
| Mitochondrial Dysfunction in Aging and Diseases of Aging |
| Autore | Haas Richard H |
| Pubbl/distr/stampa | MDPI - Multidisciplinary Digital Publishing Institute, 2019 |
| Descrizione fisica | 1 electronic resource (270 p.) |
| Soggetto non controllato |
age-related diseases
sphingolipids glaucoma ALS neurodegeneration mitochondrial dysfunction adaptive immunity senescence de-emergence innate immunity cell danger response mitochondrial transfer axonal transport cytokines mitochondrial age-related macular degeneration prevention heart failure purinergic signaling autophagy Alzheimer's disease diabetic retinopathy proteostasis 1 immunosenescence Miro1 ROS metabolism optic nerve polypharmacy eIF2? Parkin coenzyme Q10 neurodegenerative disease DNA damage skin exercise nucleotide metabolism pasteur effect stress response inflammation retina drug-induced mitochondrial toxicity neuroinflammation exosomes reactive oxygen species 25(OH)D cardiomyopathy crabtree effect insulin resistance cardiovascular disease ageing genetic mutations metabokines mitochondria multiple sclerosis aerobic healing cycle SOD1 mitophagy PINK1 type 2 diabetes integrated cell stress response morbidity and mortality ultraviolet photoageing cancer aging 25(OH)2D lysosome NAD+ Parkinson's disease |
| ISBN | 3-03921-328-8 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910367756303321 |
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Haas Richard H
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| MDPI - Multidisciplinary Digital Publishing Institute, 2019 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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mTOR in Human Diseases
| mTOR in Human Diseases |
| Autore | Dormond Olivier |
| Pubbl/distr/stampa | MDPI - Multidisciplinary Digital Publishing Institute, 2019 |
| Descrizione fisica | 1 electronic resource (480 p.) |
| Soggetto non controllato |
primary cilia
neurodegeneration nutrient sensor PI3K transcriptomics phosphorylation metabolic reprogramming autophagy Alzheimer's disease rapalogs liver angiogenesis mTOR complex MBSCs advanced biliary tract cancers Medulloblastoma epithelial to mesenchymal transition AMPK p70S6K lipid metabolism thyroid cancer sodium iodide symporter (NIS)/SLC5A5 male fertility anesthesia illumina mTOR inhibitor miRNA Hutchinson-Gilford progeria syndrome (HGPS) eIFs Emery-Dreifuss muscular dystrophy (EDMD) glucose AKT oral cavity squamous cell carcinoma (OSCC) glucose and lipid metabolism cellular signaling aging tumor microenvironment rapamycin leukemia chloral hydrate rapalogues schizophrenia T-cell acute lymphoblastic leukemia senescence lamin A/C neurotoxicity neurodevelopment inhibitor methamphetamine pulmonary fibrosis mTOR mTOR inhibitors combination therapy proteolysis fluid shear stress tumour cachexia biomarkers synapse gluconeogenesis mTOR signal pathway Sertoli cells immunosenescence miRNome protein aggregation senolytics metabolism NGS mTORC2 mTORC1 metabolic diseases IonTorrent apoptosis dopamine receptor nocodazole microenvironment everolimus acute myeloid leukemia immunotherapy spermatogenesis bone remodeling signalling targeted therapy ageing therapy NVP-BEZ235 fructose physical activity laminopathies MC3T3-E1 cells cell signaling microRNA cancer lipolysis melatonin Parkinson's disease |
| ISBN | 3-03921-061-0 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910346684303321 |
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Dormond Olivier
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| MDPI - Multidisciplinary Digital Publishing Institute, 2019 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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The Health Benefits of the Bioactive Compounds in Foods
| The Health Benefits of the Bioactive Compounds in Foods |
| Autore | Jaime Laura |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 electronic resource (234 p.) |
| Soggetto topico |
Humanities
Social interaction |
| Soggetto non controllato |
phytochemicals
antioxidant antinausea antiobesity anticancer anti-inflammatory ‘Cara Cara’ juice storage hydrophilic and lipophilic antioxidant carotenoid flavonoid degradation dried distilled spent grain (DDSG) melanoidins content structure antioxidant activity ACE-inhibitory activity beverages brewing method antioxidant potential total polyphenols content mineral composition grape stem phenolic compounds central composite rotatable design sustainable food systems pressurized liquid extraction side streams valorisation curcumin milk proteins nanoparticles antimicrobial activities bioactive peptides hypertension functional food metabolic syndrome microbiota insulin sensitivity polyphenols grape pomace donkey milk (DM) donkey colostrum (DC) mammal’s milk cow’s milk protein allergy (CMPA) biologic activity immunosenescence health benefits cryoconcentration calafate juice storage time physicochemical properties bioactive compounds sensorial analysis apitherapy royal jelly propolis bee pollen sarcopenia dietary interventions muscle skeletal muscle wasting physical performance coronavirus disease 2019 COVID-19 body composition lean body mass insulin resistance mitochondrial dysfunction satellite stem cells polysaccharide purification anti-obesity proliferation PPARγ biological activities isolation analysis mechanism of action bioaccessibility intestinal absorption bioavailability |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557361603321 |
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Jaime Laura
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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