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Cell Biology of Viral Infections
| Cell Biology of Viral Infections |
| Autore | Lozach Pierre-Yves |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 electronic resource (418 p.) |
| Soggetto topico |
Research & information: general
Biology, life sciences |
| Soggetto non controllato |
ectoderm
mesoderm human development embryogenesis interferon response interferon-induced genes self-organizing map (SOM) data portrayal epigenetic signature embryoid body TGF-β and Wnt/β-catenin pathway interferon tumor necrosis factor STAT interferon regulatory factor antiviral autoimmunity inflammation hepatitis C virus HCV erlin-1 erlin-2 host factor endoplasmic reticulum RNA replication protein production virus production lipid droplet TAP-GFP fluorescent TAP platform antigen presentation MHC I immune evasion BoHV-1 UL49.5 virus calcium channels calcium pumps virus–host interaction Ebola virus filovirus inclusion bodies NXF1 liquid organelles mRNA export cancer immunotherapy oncolytic virus herpes simplex virus immune checkpoint inhibitor angiogenesis inhibitor rabies uDISCO 3D imaging rabies pathogenicity astrocyte infection metabolism apoptosis autophagy HIV-1 spread cell-free infection cell–cell transmission 3D cultures mathematical modeling environmental restriction CAD pyrimidine synthesis HEV particle production viral replication virus entry hantavirus Tula virus replication factory RNA synthesis Golgi stress granules actin cytoskeleton nucleocapsid transport Arp2/3 complex ERAP2 ERAP2/Iso3 microbial infections alternative splicing SARS-CoV-2 host cell response coronavirus MERS-CoV SARS-CoV sialic acid Siglec antiviral peptide enveloped viruses membrane phosphatidylserine envelope disruption membrane damage antiviral autophagy galectin bacterial invasion adenovirus lysophagy ESCRT machinery cedar virus henipavirus fusion protein endocytosis biological activity feline coronavirus feline enteric coronavirus FECV feline infectious peritonitis virus FIPV feline intestinal organoids alphaviruses cell death mosquito tolerance |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557135903321 |
Lozach Pierre-Yves
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Dendritic Cell-based Immunotherapy in Solid and Haematologic Tumors
| Dendritic Cell-based Immunotherapy in Solid and Haematologic Tumors |
| Autore | Dal Col Jessica |
| Pubbl/distr/stampa | Frontiers Media SA, 2020 |
| Descrizione fisica | 1 electronic resource (125 p.) |
| Soggetto topico |
Medicine
Immunology |
| Soggetto non controllato |
dendritic cell vaccination
dendritic cell tolerization anticancer immunotherapeutic combination immune checkpoint inhibitor immunogenic cell death |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557253803321 |
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Dal Col Jessica
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| Frontiers Media SA, 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Immunotherapy, Tumor Microenvironment and Survival Signaling
| Immunotherapy, Tumor Microenvironment and Survival Signaling |
| Autore | Golubovskaya Vita |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 electronic resource (376 p.) |
| Soggetto topico |
Medicine
Clinical & internal medicine |
| Soggetto non controllato |
Autophagy
colorectal cancer immunotherapy tumor stroma tumor microenvironment immune checkpoint inhibitors chemotherapy tyrosine kinase inhibitors angiogenesis check point inhibitors programmed cell death protein 1 programmed cell death 1 ligand 1 cardiotoxicity lung metastasis CAR-T hypoxia tumor microenvironment CD19 BCMA cancer melanoma immune escape antigen loss chimeric antigen receptor electroporation lentivirus lentiviral transduction macrophages leukemia cells lytic peptides targeted therapy dendritic cells pathogenesis risk factors breast cancer resistance checkpoint targeted treatment personalized medicine pediatric solid tumors chimeric antigen receptors cancer vaccines oncolytic viral therapy immunomodulation DCLK1 tumor stem cells clonogenicity mitochondria mitochondrial transfer tunneling nanotubes triple-negative breast cancer immune checkpoint inhibitor combination therapy cancer nanomedicine tumor antigens cancer metabolism cancer immunotherapy nanoparticles immunotherapeutic agent immunomodulators tuft cells cancer stem cells immunotherapies myeloid-derived suppressor cells regulatory T cells crosstalk tumor immune evasion cell-cell contact β2 integrins CD18 CD11 CAR-T cells CD37 cell therapy tumor antigen lymphoma CAR macrophage CAR T cell solid tumors immunometabolism miRNA immunogenic cell death |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910580205403321 |
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Golubovskaya Vita
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Methods in Computational Biology
| Methods in Computational Biology |
| Autore | Carlson Ross |
| Pubbl/distr/stampa | MDPI - Multidisciplinary Digital Publishing Institute, 2019 |
| Descrizione fisica | 1 electronic resource (214 p.) |
| Soggetto non controllato |
inosine
immune checkpoint inhibitor geometric singular perturbation theory simulation BioModels Database ADAR calcium current bifurcation analysis bacterial biofilms nonlinear dynamics explanatory model turning point bifurcation oscillator workflow bioreactor integrated modeling modeling methods elementary flux modes visualization multiscale systems biology evolutionary algorithm metabolic model differential evolution reduced-order model computational model gut microbiota dysbiosis canard-induced EADs computational biology metabolic modelling methods SREBP-2 mechanistic model systems modeling biological networks macromolecular composition provenance flux balance analysis immunotherapy compartmental modeling immuno-oncology metabolic network visualization mechanism bistable switch Clostridium difficile infection bioreactor operation optimization microRNA targeting CFD simulation biomass reaction RNA editing ordinary differential equation metabolic modeling mass-action networks hybrid model multiple time scales quantitative systems pharmacology (QSP) mathematical modeling microRNA cancer parameter optimization Hopf bifurcation breast |
| ISBN | 3-03921-164-1 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910346689103321 |
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Carlson Ross
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| MDPI - Multidisciplinary Digital Publishing Institute, 2019 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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New Prognostic and Predictive Markers in Cancer Progression
| New Prognostic and Predictive Markers in Cancer Progression |
| Autore | Costantini Susan |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 electronic resource (294 p.) |
| Soggetto topico | Medicine |
| Soggetto non controllato |
MSI2
OSCC oral cancer musashi 2 prognosis N-cadherin EMT breast cancer new metastasis eribulin blood biomarker bladder cancer immune checkpoint inhibitor CD8+ T effector cells microRNA biomarkers head and neck cancer laryngeal cancer prediction metastasis lifestyle habit chemo-/radio resistance therapeutic target AKT AR castration-resistant prostate cancer (CRPC) MAPK mTOR PI3K prostate cancer therapeutic resistance WNT miRNA melanoma melanoma resistance to MAPK/MEK inhibitors resistance to immune checkpoint inhibitors TNBC BRCA1/2 HRR PDL1 TILs PI3KCA PTEN CTCs CSC pancreatic cancer K-RAS oncogene oncogene dependency targeted therapies genomic mutations transcriptomics metabolomics selenoproteins cancer HUB nodes major histocompatibility complex (MHC) human leukocyte antigen (HLA) antigen processing machinery (APM) molecules carcinogenesis tumor predisposition cancer immunotherapy pheochromocytoma paraganglioma head and neck neoplasms head and neck tumors genetic syndromes mutations hyperglycemia cardioncology nivolumab cytokines cardiotoxicity acetyltransferase cancer prognosis NAA10 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557794803321 |
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Costantini Susan
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Non-small Cell Lung Cancer: Current Therapies and New Targeted Treatments
| Non-small Cell Lung Cancer: Current Therapies and New Targeted Treatments |
| Autore | Uchino Junji |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 electronic resource (258 p.) |
| Soggetto topico | Medicine |
| Soggetto non controllato |
non-small cell lung cancer
previously treated patients phase I/II trial chemotherapy docetaxel S-1 immunotherapy rechallenge retrospective analysis pulmonary pleomorphic carcinoma prognostic factor glucose transporter 1 lung cancer multiple cancers metastasis sequencing mutation genomic diagnosis FDG-PET immune checkpoint inhibitor PD-1 prognosis RAD51B methylation PD-L1 expression predictive biomarker PD-1 blockade interstitial lung disease pulmonary fibrosis radiology and other imaging non-small-cell lung cancer epidermal growth factor receptor tyrosine kinase inhibitors TP53 mutations responsiveness targeted therapy network meta-analysis stage IIIA-N2 surgery immune checkpoint inhibitors biomarker nonsmall cell lung cancer HIP1R PD-L1 RUNX1 methylation survival EGFR-TKI T790M osimertinib immune-related adverse events endocrine disorders tumor-bearing patients PD-1 inhibitors PD-L1 inhibitors meta-analysis nivolumab Expanded Access Program real-world data daily practice prognostic factors NSCLC KRAS DNA polymerase beta platinum-based first-line adjuvant chemotherapy β-catenin lung neoplasms nucleotide-diphosphate kinase recurrence unresectable salvage surgery oligometastasis |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | Non-small Cell Lung Cancer |
| Record Nr. | UNINA-9910557489703321 |
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Uchino Junji
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Oncolytic Virus Immunotherapy
| Oncolytic Virus Immunotherapy |
| Autore | Marchini Antonio |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 electronic resource (366 p.) |
| Soggetto topico |
Medicine
Clinical & internal medicine |
| Soggetto non controllato |
oncolytic viruses
melanoma immunotherapy checkpoint inhibitors combinatory therapy reovirus oncolytic virus adenovirus oncolytic virotherapy targeting immunogenic cell death αvβ6 integrin oncolytic adenovirus cancer immunotherapy multi-stage immunostimulatory arming HSV-1 clinical trials newcastle disease virus NDV cancer immune checkpoint inhibitor PD-1 PD-L1 CTLA-4 type I interferon herpes simplex virus retargeted virus tropism retargeting tumor checkpoint inhibitor vaccination antigen-agnostic vaccination HER2 parvovirus tumor microenvironment combination therapy glioblastoma pancreatic cancer colorectal cancer measles virus vector engineering immune checkpoint blockade antitumor immune response delivery genetic modification biomarkers personalized oncolyticvirotherapy class I HLA immunosurveillance immunoediting oncogenic signaling RAS DNA methyltransferase inhibitor (DNMTi) viral mimicry epigenetic silencing adoptive T cell therapy CAR T cell pancreatic ductal adenocarcinoma vesicular stomatitis virus small molecule cancer immune therapy cancer therapy |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910566462203321 |
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Marchini Antonio
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Peptides for Health Benefits 2019 : Volume 2
| Peptides for Health Benefits 2019 : Volume 2 |
| Autore | Hernández-Ledesma Blanca |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 |
| Descrizione fisica | 1 electronic resource (342 p.) |
| Soggetto topico |
Research & information: general
Biology, life sciences |
| Soggetto non controllato |
antihypertensive peptides
functional food food-derived fermentation Chlorella sorokiniana in silico BIOPEP-UWM database proteomics bioactive peptides nano liquid chromatography tandem mass spectrometry (nanoLC-nanoESI MS/MS) apolipoprotein E amyloid fibrils Alzheimer's disease Αβ oligomer amyloid Aβ peptide glioma platelets antiproliferative assay conjugation docetaxel doxorubicin extra domain B fibronectin Fmoc/tBu peptide-drug conjugate prostate cancer solid-phase synthesis targeting acrylamide enteric nervous system galanin pig stomach formyl peptide receptors ligands diseases polymicrobial biofilms intragenic antimicrobial peptide Hs02 Pseudomonas aeruginosa Staphylococcus aureus osteostatin arthritis inflammation immune response cartilage destruction bone erosion collagen hydrolysis enzyme molecular weight sheepskin NF-κB dry-cured pork ham angiotensin I converting enzyme endothelial dysfunction molecular blind docking Lactoferricin B (Lfcin B) Histatin-5 antimicrobial peptides (AMPs) antifungal activity proteome microarray synergy temporin MRSA antimicrobial peptide human keratinocytes pseudin-2 antisepsis, peptide antibiotics neurotensin asthma T cells In situ tetramer staining MHC tetramer antigen-specific confocal microscopy fresh tissue velvet antler alcalase hydrolysate antioxidant peptide protection ability oxidative stress Crassostrea angulata pidotimod CXCR3 monocyte migration PI3K/Akt pathway T cell immunomodulant host defense peptides membrane activity copper piscidins Clostridioides difficile prolactin-releasing peptide GPR10 RF-amide peptides food intake regulation energy expenditure neuroprotection signaling gender differences dyslipidemia obesity hyperglycemia pulmonary emphysema endothelial progenitor cells angiogenic precursor cells pegylated glucagon-like peptide 1 and endothelial regeneration miiuy croaker (Miichthys miiuy) swim bladder FPYLRH antioxidant activity cytoprotective effect antimicrobial peptides antimicrobial resistance AMP identification and design biosynthesis mode of action physico-chemical properties therapeutic potential insects Cecropins Cec-analogs MDR infectious diseases airway inflammation non-atopic asthma hybrid peptide pro-inflammatory cytokines sPLA2 MDA database proteolysis SMILES code foods nutrition chronic diseases nutraceuticals peptide vaccine immune checkpoint inhibitor humanized mouse cancer antigen immune suppression vasoactive intestinal peptide VPAC1 receptor VPAC2 receptor rheumatic diseases inflammatory bowel disease central nervous system diseases type 1 diabetes Sjögren's syndrome biomarkers human antimicrobial peptides defensins cathelicidins anti-inflammatory pro-inflammatory peptide combinatorial library library design screening mutagenesis prolyl-hydroxyproline (Pro-Hyp) hydroxyprolyl-glycine (Hyp-Gly) collagen peptide fibroblasts fetal bovine serum (FBS) AMD CNV VEGFR1 multimeric peptides oral delivery colorectal cancer cancer stem cells chemoprevention bioactive peptide lunasin ACE-inhibitory activity whey peptides molecular docking hypertension antibiotic resistance cystic fibrosis cryptides anti-biofilm peptides synergistic effects |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | Peptides for Health Benefits 2019 |
| Record Nr. | UNINA-9910557492903321 |
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Hernández-Ledesma Blanca
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Peptides for Health Benefits 2019 : Volume 1
| Peptides for Health Benefits 2019 : Volume 1 |
| Autore | Hernández-Ledesma Blanca |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 |
| Descrizione fisica | 1 electronic resource (340 p.) |
| Soggetto topico |
Research & information: general
Biology, life sciences |
| Soggetto non controllato |
antihypertensive peptides
functional food food-derived fermentation Chlorella sorokiniana in silico BIOPEP-UWM database proteomics bioactive peptides nano liquid chromatography tandem mass spectrometry (nanoLC-nanoESI MS/MS) apolipoprotein E amyloid fibrils Alzheimer's disease Αβ oligomer amyloid Aβ peptide glioma platelets antiproliferative assay conjugation docetaxel doxorubicin extra domain B fibronectin Fmoc/tBu peptide-drug conjugate prostate cancer solid-phase synthesis targeting acrylamide enteric nervous system galanin pig stomach formyl peptide receptors ligands diseases polymicrobial biofilms intragenic antimicrobial peptide Hs02 Pseudomonas aeruginosa Staphylococcus aureus osteostatin arthritis inflammation immune response cartilage destruction bone erosion collagen hydrolysis enzyme molecular weight sheepskin NF-κB dry-cured pork ham angiotensin I converting enzyme endothelial dysfunction molecular blind docking Lactoferricin B (Lfcin B) Histatin-5 antimicrobial peptides (AMPs) antifungal activity proteome microarray synergy temporin MRSA antimicrobial peptide human keratinocytes pseudin-2 antisepsis, peptide antibiotics neurotensin asthma T cells In situ tetramer staining MHC tetramer antigen-specific confocal microscopy fresh tissue velvet antler alcalase hydrolysate antioxidant peptide protection ability oxidative stress Crassostrea angulata pidotimod CXCR3 monocyte migration PI3K/Akt pathway T cell immunomodulant host defense peptides membrane activity copper piscidins Clostridioides difficile prolactin-releasing peptide GPR10 RF-amide peptides food intake regulation energy expenditure neuroprotection signaling gender differences dyslipidemia obesity hyperglycemia pulmonary emphysema endothelial progenitor cells angiogenic precursor cells pegylated glucagon-like peptide 1 and endothelial regeneration miiuy croaker (Miichthys miiuy) swim bladder FPYLRH antioxidant activity cytoprotective effect antimicrobial peptides antimicrobial resistance AMP identification and design biosynthesis mode of action physico-chemical properties therapeutic potential insects Cecropins Cec-analogs MDR infectious diseases airway inflammation non-atopic asthma hybrid peptide pro-inflammatory cytokines sPLA2 MDA database proteolysis SMILES code foods nutrition chronic diseases nutraceuticals peptide vaccine immune checkpoint inhibitor humanized mouse cancer antigen immune suppression vasoactive intestinal peptide VPAC1 receptor VPAC2 receptor rheumatic diseases inflammatory bowel disease central nervous system diseases type 1 diabetes Sjögren's syndrome biomarkers human antimicrobial peptides defensins cathelicidins anti-inflammatory pro-inflammatory peptide combinatorial library library design screening mutagenesis prolyl-hydroxyproline (Pro-Hyp) hydroxyprolyl-glycine (Hyp-Gly) collagen peptide fibroblasts fetal bovine serum (FBS) AMD CNV VEGFR1 multimeric peptides oral delivery colorectal cancer cancer stem cells chemoprevention bioactive peptide lunasin ACE-inhibitory activity whey peptides molecular docking hypertension antibiotic resistance cystic fibrosis cryptides anti-biofilm peptides synergistic effects |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | Peptides for Health Benefits 2019 |
| Record Nr. | UNINA-9910557631703321 |
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Hernández-Ledesma Blanca
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Strategies to Improve Antineoplastic Activity of Drugs in Cancer Progression
| Strategies to Improve Antineoplastic Activity of Drugs in Cancer Progression |
| Autore | Stefanachi Angela |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 electronic resource (416 p.) |
| Soggetto topico |
Research & information: general
Biology, life sciences |
| Soggetto non controllato |
EGR-1
flavonoid (E)-5-((4-oxo-4H-chromen-3-yl)methyleneamino)-1-phenyl-1H-pyrazole-4-carbonitrile MDA-MB-231 MMP9 TNFα pancreatic ductal adenocarcinoma cyclodextrin inclusion complex phase solubility studies preformulation studies biphenylnicotinamide derivatives dual inhibitor EGFR VEGFR2 ligand-based pharmacophore molecular docking molecular dynamics leukemias doxorubicin inflammation drug delivery tumor targeting elastin-like polypeptide cell penetrating peptide matrix metalloproteinase doxorubicin resistance photosensitizer delivery system PAMAM dendrimer photodynamic therapy cytotoxicity phototoxicity colorectal adenocarcinoma dicarboximides chemical synthesis apoptosis kinases anticancer gene profiling SAR biomarkers colorectal cancer early detection examination liquid biopsy personalized medicine tumor treatment exosomes ctDNA CTC cytotoxic activity pyrazole derivatives MTT assay ADMET analysis single-crystal diffraction FTIR spectroscopy NMR spectroscopy thermogravimetric analysis acute myelogenous leukemia platelets microparticles γδ T cells immunotherapy tumor resistance combination therapy tumor microenvironment immune checkpoint inhibitor neuroblastoma molecular iodine cyclophosphamide xenografts metronomic therapy tamoxifen CYP2D6 MCF-7 Ishikawa cells SERM TNBC uterotrophic α-mangostin poly(amidoamine) dendrimer targeted drug delivery biotin targeting glioblastoma multiforme squamous cell carcinoma antiparasitic therapy diclofenac indomethacin oleanolic acid derivative conjugates NF-κB Nrf2 MAPKs PSN-1 cells reactive oxygen species glioblastoma brain tumor extracellular vesicles pancreatic cancer paclitaxel clathrin endocytosis sulforaphane nicotine metalloproteinase-9 gastric cancer cell invasion Arylquin 1 colon cancer tumor progression azelastine oxidative stress autophagy mitotic catastrophe chronic myeloid leukemia imatinib tyrosine kinase ketoconazole P-glycoprotein drug efflux transporter non-small-cell lung cancer cisplatin resistance aldehyde dehydrogenase isothiocyanates disulfiram epithelial to mesenchymal transition aminopeptidase N acetamidophenones Schiff bases semicarbazones thiosemicarbazones inhibition of proliferation |
| ISBN | 3-0365-5927-2 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910639990003321 |
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Stefanachi Angela
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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