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Anticancer Drugs 2021
| Anticancer Drugs 2021 |
| Autore | Meegan Mary J |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 electronic resource (594 p.) |
| Soggetto topico |
Research & information: general
Chemistry |
| Soggetto non controllato |
thymidylate synthase
cytotoxicity 1,2,3-triazole 1,3,4-oxadiazole 5-fluoruracil pemetrexed docking 3,4'-bis-guanidino 3-amino-4'-guanidino diphenyl ether phenyl pyridyl ether intramolecular hydrogen bond cancer cell viability HL-60 BRAF apoptosis thieno[2,3-d][1,2,3]triazine acetamide H1299 HER2 EGFR Bcl-2 inhibitors Indole-based analogues benzimidazole MTT cytotoxic assay cell cycle analysis DNA fragmentation ELISA solid/lipid nanoparticles phenstatin letrozole tubulin polymerisation inhibitor aromatase inhibitor breast cancer hybrid molecule dual-targeting molecule designed multiple ligand NaMSA cyclophosphamide histopathology testis urinary bladder anticancer agents enantioselective synthesis gastric adenocarcinoma tryptophanol concentration-guided dosing model informed dosing physiologically based pharmacokinetics sorafenib tyrosil-DNA-phosphodiesterase 1 adamantane resin acid TDP1 cytotoxic agents apoptosis induction HT-29 cells MDA-MB-231 cells mechanism prediction STAT inhibitors miR-21 hydrazide derivatives nitrogen scaffolds mitoxantrone cardiotoxicity inflammation oxidative stress age cumulative dose Trk NTRK tissue-agnostic larotrectinib entrectinib Trk fusion protein kinase inhibitors USFDA cancer patent review generic product doxazosin MD simulations combretastatin A-4 cytotoxic activity hybrid compounds indazole mucin MUC1 MUC16 immunotherapy cancer vaccine CAR (chimeric antigen receptor) ADC (antibody-drug conjugate) thiourea interleukin-6 trypan blue assay chalcones exportin-1 covalent binding CovDock anticancer activity xanthone in vitro in vivo isolation synthesis heterocyclic compound benzenesulfonamides imidazoles alkylated colony formation tumor spheroids HDAC inhibitors chalcone dual inhibitors carvedilol kidney toxicity 7-deaza-4'-thioadenosine derivatives multi-kinase inhibitor anticancer nucleoside Imiquimod drug efflux multidrug resistance Toll-Like Receptor |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910576874303321 |
Meegan Mary J
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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The Origin and Early Evolution of Life: Prebiotic Chemistry of Biomolecules
| The Origin and Early Evolution of Life: Prebiotic Chemistry of Biomolecules |
| Autore | Fiore Michele |
| Pubbl/distr/stampa | MDPI - Multidisciplinary Digital Publishing Institute, 2019 |
| Descrizione fisica | 1 electronic resource (288 p.) |
| Soggetto non controllato |
minerals
inosine carbamic acid prebiotic chemistry pentopyranose nucleic acid catalysis MVC architecture pattern and biological information carbon dioxide-ammonia ices stability as a selection pressure ribozyme and tRNA translation and the genetic code AnyLogic software for computer simulation of translation machine Darwinian evolution prebiotic information system genetic code origin electrochemistry coevolution of translation machine and the genetic code digit multiplicity thermodynamic bottleneck abasic oligomers selection nucleotide stability AICAR tRNA-synthetase hypercycle nucleotide oligomerization origin of life thioester dry-wet cycles Chemomimesis population growth tRNA and mRNA diversity early peptides Molecular Darwinism tRNA accretion model replication aldol reaction hydrothermal vents base pairing numerical codons abiogenesis purine precursor peptide/RNA world information ab initio molecular dynamics RNA cysteine nucleotide and nucleoside synthesis thiol-rich peptides novel metalloproteins transmission function energy currency anharmonicity arabinopyranose nucleic acid bridge peptide and aaRS aminonitriles mechanochemistry prebiotic polymerization origins of life encoding carbon fixation infrared spectra phosphoryl transfer metabolism growth order layered double hydroxide (LDH) clay molecular clocks Monte Carlo binary patterned amino acid sequences network expansion simulation prebiotic soup nucleotidyltransferases mixed anhydride phosphates translation ribosome pentose diphosphate monosaccharides systems chemistry reduction imidazoles protein design |
| ISBN | 3-03921-607-4 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | Origin and Early Evolution of Life |
| Record Nr. | UNINA-9910367749403321 |
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Fiore Michele
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| MDPI - Multidisciplinary Digital Publishing Institute, 2019 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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