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Anticancer Drugs 2021
| Anticancer Drugs 2021 |
| Autore | Meegan Mary J |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 online resource (594 p.) |
| Soggetto topico |
Chemistry
Research & information: general |
| Soggetto non controllato |
1,2,3-triazole
1,3,4-oxadiazole 3-amino-4'-guanidino 3,4'-bis-guanidino 5-fluoruracil 7-deaza-4'-thioadenosine derivatives acetamide adamantane ADC (antibody-drug conjugate) age alkylated anticancer anticancer activity anticancer agents apoptosis apoptosis induction aromatase inhibitor Bcl-2 inhibitors benzenesulfonamides benzimidazole BRAF breast cancer cancer cancer cell viability cancer vaccine CAR (chimeric antigen receptor) cardiotoxicity carvedilol cell cycle analysis chalcone chalcones colony formation combretastatin A-4 concentration-guided dosing covalent binding CovDock cumulative dose cyclophosphamide cytotoxic activity cytotoxic agents cytotoxicity designed multiple ligand diphenyl ether DNA fragmentation docking doxazosin drug efflux dual inhibitors dual-targeting molecule EGFR ELISA enantioselective synthesis entrectinib exportin-1 gastric adenocarcinoma generic product H1299 HDAC inhibitors HER2 heterocyclic compound histopathology HL-60 HT-29 cells hybrid compounds hybrid molecule hydrazide derivatives imidazoles Imiquimod immunotherapy in vitro in vivo indazole Indole-based analogues inflammation interleukin-6 intramolecular hydrogen bond isolation kidney larotrectinib letrozole MD simulations MDA-MB-231 cells mechanism prediction miR-21 mitoxantrone model informed dosing MTT cytotoxic assay MUC1 MUC16 mucin multi-kinase inhibitor multidrug resistance n/a NaMSA nitrogen scaffolds NTRK nucleoside oxidative stress patent review pemetrexed phenstatin phenyl pyridyl ether physiologically based pharmacokinetics protein kinase inhibitors resin acid solid/lipid nanoparticles sorafenib STAT inhibitors synthesis TDP1 testis thieno[2,3-d][1,2,3]triazine thiourea thymidylate synthase tissue-agnostic Toll-Like Receptor toxicity Trk Trk fusion trypan blue assay tryptophanol tubulin polymerisation inhibitor tumor spheroids tyrosil-DNA-phosphodiesterase 1 urinary bladder USFDA xanthone |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910576874303321 |
Meegan Mary J
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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The origin and Early Evolution of Life : : Prebiotic Chemistry of Biomolecules / / Michele Fiore
| The origin and Early Evolution of Life : : Prebiotic Chemistry of Biomolecules / / Michele Fiore |
| Autore | Fiore Michele |
| Pubbl/distr/stampa | MDPI - Multidisciplinary Digital Publishing Institute, 2019 |
| Descrizione fisica | 1 electronic resource (288 p.) |
| Soggetto topico | Chemistry |
| Soggetto non controllato |
minerals
inosine carbamic acid prebiotic chemistry pentopyranose nucleic acid catalysis MVC architecture pattern and biological information carbon dioxide-ammonia ices stability as a selection pressure ribozyme and tRNA translation and the genetic code AnyLogic software for computer simulation of translation machine Darwinian evolution prebiotic information system genetic code origin electrochemistry coevolution of translation machine and the genetic code digit multiplicity thermodynamic bottleneck abasic oligomers selection nucleotide stability AICAR tRNA-synthetase hypercycle nucleotide oligomerization origin of life thioester dry-wet cycles Chemomimesis population growth tRNA and mRNA diversity early peptides Molecular Darwinism tRNA accretion model replication aldol reaction hydrothermal vents base pairing numerical codons abiogenesis purine precursor peptide/RNA world information ab initio molecular dynamics RNA cysteine nucleotide and nucleoside synthesis thiol-rich peptides novel metalloproteins transmission function energy currency anharmonicity arabinopyranose nucleic acid bridge peptide and aaRS aminonitriles mechanochemistry prebiotic polymerization origins of life encoding carbon fixation infrared spectra phosphoryl transfer metabolism growth order layered double hydroxide (LDH) clay molecular clocks Monte Carlo binary patterned amino acid sequences network expansion simulation prebiotic soup nucleotidyltransferases mixed anhydride phosphates translation ribosome pentose diphosphate monosaccharides systems chemistry reduction imidazoles protein design |
| ISBN |
9783039216079
3039216074 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910367749403321 |
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Fiore Michele
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| MDPI - Multidisciplinary Digital Publishing Institute, 2019 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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