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Amide Bond Activation
| Amide Bond Activation |
| Autore | Szostak Michal |
| Pubbl/distr/stampa | MDPI - Multidisciplinary Digital Publishing Institute, 2019 |
| Descrizione fisica | 1 electronic resource (466 p.) |
| Soggetto non controllato |
N-heterocyclic carbene
non planar amide ruthenium (Ru) physical organic chemistry gemcitabine prodrug pyramidal amides bridged sultams catalysis dipeptides N-(1-naphthyl)acetamide C-N ? bond cleavage steric effects peptide bond cleavage transition-metal-free palladium N-heterocyclic carbenes (NHCs) addition reaction C–O activation rhodium metal complexes carbanions thioamidation amide bond intramolecular catalysis antiviral activity additivity principle pre-catalysts C–N bond cleavage bridged lactams C–H acidity arynes twisted amides organic synthesis amination Suzuki-Miyaura tert-butyl cyclopentadienyl complexes C-S formation enzymes DFT study sulfonamide bond N HERON reaction primaquine entropy amide activation amidation synthesis amide hydrolysis carbonylicity amide bond activation amide bond resonance aminosulfonylation molecular dynamics model compound in situ amide homogeneous catalysis heterocycles anomeric effect multi-component coupling reaction kinetic excited state C–H bond cleavage palladium catalysis amides thiourea formylation alkynes cis/trans isomerization amide C–N bond activation intein C-H functionalization succindiamide amide bonds crown ether aminoacylation directing groups cytostatic activity reaction thermodynamics acyl transfer transition metals N-dimethylformamide DMAc acylative cross-coupling C-H/C-N activation nickel catalysis antibacterial screening sodium aryl thioamides Winkler-Dunitz parameters catalyst N-dimethylacetamide base-catalyed hydrolysis nitrogen heterocycles cross-coupling insertion amidicity nitro-aci tautomerism activation carbonylation transamidation amine distortion Pd-catalysis rotational barrier energy hypersensitivity N–C activation metabolic stability [2+2+2] annulation twisted amide protease cyanation amide resonance trialkylborane catalysts biofilm eradication pharmacokinetics pancreatic cancer cells DMF aryl esters Michael acceptor fumardiamide water solvation ester bond activation cyclization nuclear magnetic resonance secondary amides reaction mechanism density functional theory density-functional theory amino acid transporters |
| ISBN | 3-03921-204-4 |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910346843703321 |
Szostak Michal
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| MDPI - Multidisciplinary Digital Publishing Institute, 2019 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Bacterial Interactions with Dental and Medical Materials
| Bacterial Interactions with Dental and Medical Materials |
| Autore | Melo Mary Anne |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 electronic resource (248 p.) |
| Soggetto topico | Research & information: general |
| Soggetto non controllato |
polymer
dental antibacterial antifouling hydroxyapatite star-shaped hydrophobicity acrylic acid oral composition antimicrobial effect biofilms cytotoxicity dental resins physicochemical properties mechanical properties quaternary ammonium methacrylates dental materials dentistry adhesives light-curing of dental adhesives composite resins methylmethacrylate oxides cerium polymers dentine bonding agents anti-bacterial agents dental caries biocompatible materials quaternary ammonium compounds antimicrobial ceramic coating silicon carbide fluoride(s) biofilm(s) Streptococcus mutans bioreactor(s) enamel composite materials biomaterials nanostructured materials chronic wounds infection chick embryo CAM ex ovo bioactive desensitizer hypersensitivity SEM nanoparticle nanohydroxyapatite microshear bond strength phosphoric acid self-etch porous bioceramics wollastonite sol-gel technology spark plasma sintering-reactive synthesis bacterial test surface modification coatings implant biofilm silver copper polylysine dental composites protein repellent restorations zwitterionic polymers dental composite antibiofilm dental nanocomposite calcium fluoride nanoparticles remineralization oral biofilm electrospinning nano-hydroxyapatite toxicity bone regeneration white spot lesions orthodontic |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557129203321 |
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Melo Mary Anne
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Biomarkers in Drug Hypersensitivity
| Biomarkers in Drug Hypersensitivity |
| Autore | Emanuela Corsini |
| Pubbl/distr/stampa | Frontiers Media SA, 2017 |
| Descrizione fisica | 1 electronic resource (104 p.) |
| Collana | Frontiers Research Topics |
| Soggetto non controllato |
models
hypersensitivity haptenization biomarkers genotyping drug metabolism phenotyping drug |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910227346103321 |
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Emanuela Corsini
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| Frontiers Media SA, 2017 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Centenarians-A Model to Study the Molecular Basis of Lifespan and Healthspan
| Centenarians-A Model to Study the Molecular Basis of Lifespan and Healthspan |
| Autore | Puca Annibale |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 electronic resource (204 p.) |
| Soggetto topico |
Research & information: general
Biology, life sciences |
| Soggetto non controllato |
aging
alternative therapy composition of royal jelly dietary interventions healthspan lifespan longevity royal jelly IGF-1 oxidative stress ageing nematode immunosenescence probiotic bacteria pathogen protection food allergy elderly hypersensitivity gut allergy inflammation redoxomics glutathione meniere's disease neurodegenerative diseases healthy aging DNA methylation epigenetic clocks telomere length centenarians exosomes serum functional enrichment analysis ingenuity pathway analysis miRNA-mRNA networks aging-related disease Di (2-Ethylhexyl) pthalate Hericium erinaceus vitagenes apoptosis mitochondrial respiratory complexes C. elegans polyphenols olive oil Parkinson's disease β-Dystroglycan cellular senescence lamin B1 DNA-damage response defective mitosis |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557783503321 |
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Puca Annibale
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Flavonoids and Their Disease Prevention and Treatment Potential
| Flavonoids and Their Disease Prevention and Treatment Potential |
| Autore | Rupasinghe H.P. Vasantha |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 electronic resource (346 p.) |
| Soggetto topico |
Humanities
Social interaction |
| Soggetto non controllato |
luteolin
apigenin bacoside A bacopaside I vasorelaxation isorhamnetin flavonoid bacterial sepsis toll-like receptor 4 inflammation citrus flavonoids neohesperidin anti-aging activity chronological lifespan synergistic effect clinical trials natural products hyperalgesia allodynia analgesia hypersensitivity cytokines NF-kB defatted pitaya seed extraction phenolic content flavonoid content antioxidant activity response surface methodology flavonoids aglycons glycosides IL-1β TNF-α IL-6 IL-8 pro-inflammatory cytokines Acer okamotoanum afzelin isoquercitrin obesity quercitrin aspirin cancer prevention hydroxybenzoic acids cell cycle CDKs colorectal cancer infectious diseases amoebiasis Mexican oregano bioguided isolation antiprotozoal agents flavones cancer microbiome molecular mechanisms gene and protein regulatory networks macrophages NF-κB IKKβ, inflammatory cytokines apoptosis foods for health tangeretin cancer stem cells Stat3 citrus CD44+/CD24− phytochemicals flavonoids and their derivatives phytomedicine COVID-19 SARS-COV-2 smart nanoparticles non-flavonoids membrane PUFAs profile cell morphology human colon cancer cells cranberry urinary tract infections UTIs uropathogenic Escherichia coli UPEC flavan-3-ols A-type proanthocyanidins phenolic metabolites antiadhesive activity probiotics anthocyanin tobacco-specific nitrosamine carcinogenesis cell proliferation cancer chemoprevention lung cancer chalcones DNA damage anticancer activity canine cancer cell lines angiogenesis in-vivo angiogenesis CAM assay SAR cognition passive avoidance test memory extinction mice microglia neuroprotection black rice cyanidin-3-O-glucoside wood sterols dyslipidemia CVD |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557505903321 |
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Rupasinghe H.P. Vasantha
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Food Allergies in Modern Life
| Food Allergies in Modern Life |
| Autore | Manti Sara |
| Pubbl/distr/stampa | MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 electronic resource (202 p.) |
| Soggetto topico |
Research & information: general
Biology, life sciences Food & society |
| Soggetto non controllato |
children
adolescents eosinophilic esophagitis eosinophilic gastrointestinal disorders growth failure to thrive malnutrition undernutrition obesity vitamin non-IgE gastrointestinal food allergy fecal biomarkers IgG and IgG4 allergen-specific lymphocyte stimulation test oral food challenge atopy patch test clinical score endoscopy reflux GER GERD cow’s milk allergy CMA infants hydrolyzed formula alginate thickened formula cross-reaction flour food allergy individualized diagnostics legumes lupine lipid transfer protein peanut profilin hazelnut hypersensitivity component-resolved diagnostics Cor a 1 Cor a 14 Cor a 9 IgE allergy environmental factors primary prevention functional abdominal pain disorders functional dyspepsia irritable bowel syndrome allergen sensitization Gly m 4 Caco-2/Immune cells co-culture cytokine nsLTP plant-food allergy Pru p 3 peach nut Rosaceae fruit ISAC monoclonal antibodies biologics adults almond almond allergens nutrition |
| ISBN | 3-0365-5168-9 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910619468103321 |
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Manti Sara
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| MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Osseointegrated Oral implants : Mechanisms of Implant Anchorage, Threats and Long-Term Survival Rates
| Osseointegrated Oral implants : Mechanisms of Implant Anchorage, Threats and Long-Term Survival Rates |
| Autore | Albrektsson Tomas |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 |
| Descrizione fisica | 1 electronic resource (368 p.) |
| Soggetto topico | Medicine |
| Soggetto non controllato |
osseointegration
dental implant peri-implantitis ligature-induced peri-implantitis aseptic loosening systematic review immune system biomaterials foreign body reaction in vivo study oral implants marginal bone loss immunomodulation mechanotransduction Crestal bone loss osseosufficiency osseoseparation photoacoustic ultrasound brain-bone axis overloading radiography CBCT (cone beam computerized tomography) osteogenesis osteotomy bone healing bone chips drilling tool design fused deposition modeling polyether ether ketone biocomposite orthopedic implant oral implant mechanical properties wettability topography biocompatibility cell adhesion peri-implant endosseous healing dental implantation alveolar bone loss alveolar bone remodeling/regeneration bone biology finite element analysis (FEA) biomechanics cell plasticity dental implants electron microscopy scanning transmission electron microscopy bone-implant interface bone loss overdenture implant survival implant surface soft tissue split-mouth design oral health-related quality of life patient-reported outcome measures biomaterial bone immune implant healing titanium PEEK Cu micro-RNA microarray predictive biomarker epigenomics mucositis diagnosis over-treatment iatrogenic damage abutment height subcrestal implants implant insertion depth vertical mucosal thickness biological width implant installation anchorage technique histology intraosseous temperature finite element model ligature induced peri-implantitis arthroplasty replacement hip hypersensitivity contact allergy and immunology cytokines Interleukin-8 surface properties materials testing implant contamination scanning electron microscopy energy-dispersive X-ray spectrometry convergence clinical study biofilm infection perio-prosthetic joint infection periimplantitis electrolytic cleaning zirconia insertion heat bone damage early loss augmentation air flow re-osseointegration classification of bone defects dog study |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | Osseointegrated Oral implants |
| Record Nr. | UNINA-9910557410103321 |
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Albrektsson Tomas
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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TRP Channels in Health and Disease
| TRP Channels in Health and Disease |
| Autore | Dietrich Alexander |
| Pubbl/distr/stampa | MDPI - Multidisciplinary Digital Publishing Institute, 2019 |
| Descrizione fisica | 1 electronic resource (266 p.) |
| Soggetto non controllato |
transient receptor potential channels
photochromic ligands elementary immunology Purkinje cell EPSC substance P chemicals organ toxicity lymphocytes HSP70 physiology bioavailable inflammatory bowel disease platelets pollutants yeast regulatory T cells kinase Saccharomyces cerevisiae manganese cerebellum TRP channel NHERF inflammation nanoHPLC-ESI MS/MS TRPM7 chemical probes TRPM8 dorsal column nuclei TRPV2 TRPV3 calcitonin gene-related peptide TRPV1 ion channels transient receptor potential 2D gel electrophoresis MALDI-TOF MS(/MS) TRPV4 overproduction sulfur mustard oxidative stress graft versus host disease menthol topical chemosensor AP18 calcium signalling mucosal epithelium cuneate nucleus production platform TRPC channels ulcerative colitis channel structure xerostomia neutrophils cardiovascular system TRPC5 TRPC6 TRPC3 TRPC4 calcium signaling protein purification adipose tissue transient receptor potential (TRP) channels sodium TH17 diacylglycerol hypersensitivity TRPY1 GABAB HEK293 thrombosis ion channel TRPC pathophysiology SMAD toxicology endothelium calcium proteomics TRPA1 salivary glands TRP channels lipid mediators sensors radiation TRPM4 channel human medulla oblongata mGluR1 small molecules TRPC3 pharmacology |
| ISBN | 3-03921-083-1 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910674009603321 |
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Dietrich Alexander
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| MDPI - Multidisciplinary Digital Publishing Institute, 2019 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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