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Celebrating 120 Years of Butantan Institute Contributions for Toxinology
| Celebrating 120 Years of Butantan Institute Contributions for Toxinology |
| Autore | Moura-Da-Silva Ana Maria |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 online resource (408 p.) |
| Soggetto topico |
Biology, life sciences
Research & information: general |
| Soggetto non controllato |
adhesion molecules
analgesic peptide animal toxins antibacterial activity antibody fragment anticoagulants antimicrobial activity antivenom bioisosterism Bitis arietans venom (BaV) blister Bothrops Bothrops atrox Bothrops jararaca Bothrops phospholipases A2 breast cancer cathepsin L cell-signaling centipede chilopoda crotoxin Cryptops iheringi cysteine proteases inhibitor cytokines cytokines and chemokines cytolysins DAMPs drug discovery ELISA envenoming epithelial-mesenchymal transition fish venoms glial cells Haementeria vizottoi hemagglutinating activity HF3 human plasma Hyalomma dromedarii hyperalgesia hypotensins IL-17 individual variability inflammation innovation Kn-Ba lactation leech leukocyte-endothelium interactions lipid mediators local damage Lonomia MALDI-ToF mass spectrometry maternal care metalloproteases microcirculation monoclonal antibody multifunctionality n/a nattectin NEP inhibition neurodegeneration neurodegenerative disease oral tolerance peptides PGE2 pore formation protein kinase C proteolysis proteome recombinant cystatin recombinant protein reverse-phase HPLC salivary glands scorpion accidents seizure threshold serpin signaling pathways skin secretion snake venom snake venom metalloproteinase snakebite snakes spheroid model STEC Stx2 Thalassophryne THP-1 macrophages thrombin inhibitor Tityus serrulatus toxin toxinology toxins transcriptome tumor stroma venom venom components venom heterogeneity venomics venoms β-defensins |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910674030303321 |
Moura-Da-Silva Ana Maria
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Flavonoids and Their Disease Prevention and Treatment Potential
| Flavonoids and Their Disease Prevention and Treatment Potential |
| Autore | Rupasinghe H.P. Vasantha |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 online resource (346 p.) |
| Soggetto topico |
Humanities
Social interaction |
| Soggetto non controllato |
A-type proanthocyanidins
Acer okamotoanum afzelin aglycons allodynia amoebiasis analgesia angiogenesis anthocyanin anti-aging activity antiadhesive activity anticancer activity antioxidant activity antiprotozoal agents apigenin apoptosis aspirin bacopaside I bacoside A bacterial sepsis bioguided isolation black rice cyanidin-3-O-glucoside CAM assay cancer cancer chemoprevention cancer prevention cancer stem cells canine cancer cell lines carcinogenesis CD44+/CD24− CDKs cell cycle cell morphology cell proliferation chalcones chronological lifespan citrus citrus flavonoids clinical trials cognition colorectal cancer COVID-19 cranberry CVD cytokines defatted pitaya seed DNA damage dyslipidemia extraction flavan-3-ols flavones flavonoid flavonoid content flavonoids flavonoids and their derivatives foods for health gene and protein regulatory networks glycosides human colon cancer cells hydroxybenzoic acids hyperalgesia hypersensitivity IKKβ, inflammatory cytokines IL-1β IL-6 IL-8 in-vivo angiogenesis infectious diseases inflammation isoquercitrin isorhamnetin lung cancer luteolin macrophages membrane PUFAs profile memory extinction Mexican oregano mice microbiome microglia molecular mechanisms n/a natural products neohesperidin neuroprotection NF-kB NF-κB non-flavonoids obesity passive avoidance test phenolic content phenolic metabolites phytochemicals phytomedicine pro-inflammatory cytokines probiotics quercitrin response surface methodology SAR SARS-COV-2 smart nanoparticles Stat3 synergistic effect tangeretin TNF-α tobacco-specific nitrosamine toll-like receptor 4 UPEC urinary tract infections uropathogenic Escherichia coli UTIs vasorelaxation wood sterols |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557505903321 |
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Rupasinghe H.P. Vasantha
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Opioids and Their Receptors : Present and Emerging Concepts in Opioid Drug Discovery
| Opioids and Their Receptors : Present and Emerging Concepts in Opioid Drug Discovery |
| Autore | Spetea Mariana |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 |
| Descrizione fisica | 1 online resource (358 p.) |
| Soggetto topico | Medicine |
| Soggetto non controllato |
(−)-N-phenethylnorhydromorphone analogs
[35S]GTPgammaS assay [Dmt1]DALDA 14-methoxycodeine-6-O-sulfate 1H-NMR experiments 6β-naltrexol abuse agonist allodynia analgesia analgesics antagonist arrestin recruitment beta-arrestin bias factor biased agonism biased agonist biased agonists biased ligands biased signaling bifunctional ligands binding binding affinity BNTX buprenorphine chronic constriction injury (CCI) codeine codeine-6-O-sulfate DADLE DALDA DAMGO delta opioid receptor dependence design and synthesis dihydrocodeine diphenethylamines docking dysbiosis fentanyl forskolin-induced cAMP accumulation assays functional assay G-protein bias heteromer hyperalgesia interaction fingerprints internalization inverse agonist ischemia kappa opioid receptor KGOP01 Leu-enkephalin loperamide lysosomes macrocyclic tetrapeptide mechanism elucidation misuse mitragynine molecular docking molecular dynamics molecular modeling & MOR and DOR agonists morphinan morphine mu opioid receptor mu receptor multifunctional ligands n/a naltrexone neonatal opioid withdrawal syndrome neurokinin-1 receptor neutral antagonist NTI derivative opioid opioid drugs opioid liabilities opioid peptide opioid peptides opioid peptides and peptidomimetics opioid receptors opioid side effects opioids over-the-counter drugs pain therapy partial agonism partial agonist peptide synthesis peripheral analgesic tolerance peripheral antinociception peripheral µ-opioid receptors pharmacology plasma stability potassium channels primary hippocampal culture PZM21 racemic synthesis of β2-amino acids receptor binding studies receptor model respiration respiratory depression selectivity simulation SR-17018 structure-activity relationships sulfonamide TAPP tolerance writhing test zerumbone β-arrestin recruitment assays β2-amino acids β2-Homo-amino acids δ opioid receptor δ opioid receptor antagonist μ opioid receptor µ opioid receptor µ-opioid receptor |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | Opioids and Their Receptors |
| Record Nr. | UNINA-9910557108003321 |
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Spetea Mariana
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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