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ABC Transporters in Human Diseases
| ABC Transporters in Human Diseases |
| Autore | Falguières Thomas |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 online resource (494 p.) |
| Soggetto topico |
Biology, life sciences
Research & information: general |
| Soggetto non controllato |
5' untranslated region
AAV ABC ABC (ATP-binding cassette) transporters ABC transporter ABC transporters ABCA subfamily ABCA7 ABCB1 ABCB11 ABCB4 ABCC2 ABCC6 ABCG2 ABCG2 genotype ABCG5 ABCG5/G8 ABCG8 adrenoleukodystrophy Alzheimer's disease amyloid-beta anticancer antifungal resistance atherosclerosis ATP-binding cassette transporter ATP-binding cassette transporter A1 (ABCA1) Aβ peptides BCRP beta-amyloid bile salts bile secretion bioinformatics blood-brain barrier breast cancer BRIC BSEP calcification cAMP cancer cellular ATP efflux chaperones cholesterol cholesterol homeostasis cis-acting elements clinico-genetic analysis competitive allele-specific PCR disease-free survival drug action drug transport dyslipidemia early-onset gout erlotinib ethnic specificity fatty acids functional divergence gall stone gene therapy generalized arterial calcification of infancy genetic variations gout HDL-C homology modeling hyperuricemia intracellular traffic intrahepatic cholestasis invasion MDR3 mechanism mechanism of action membrane protein microparticles migration molecular partners MRP1 MRP4 multidrug resistance multidrug transporter mutagenesis mutations n/a neuron next-generation sequencing NT5E P-glycoprotein peroxisome PET PFIC PFIC2 phagocytosis phosphatidylcholine phytosterol polar relay polymorphisms precision medicine proliferation pseudoxanthoma elasticum Pseudoxanthoma elasticum (PXE) pyrophosphate RAB GTPase rare variant regulatory extension regulatory insertion reverse cholesterol transport Roma serum uric acid single nucleotide polymorphism sitosterolemia SK-N-SH SNP SUA-lowering therapy substrate-binding site tariquidar taxol therapies therapy response TNAP trafficking transport transporter type 2 diabetes urate urate transporter uric acid xenosterol yeast |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910674029103321 |
Falguières Thomas
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Advances in Ginsenosides
| Advances in Ginsenosides |
| Autore | Chen Jen-Tsung |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 online resource (264 p.) |
| Soggetto topico | Medicine |
| Soggetto non controllato |
(20S)G-Rh2
allergy American ginseng anti-cancer anti-diabetic anti-inflammation Anxa2 Asian ginseng bioconversion bioreactor biotechnology biotransformation cell proliferation cell suspension cerebral ischemia and reperfusion injury clinical trials complete genome sequence compound M1 dammarane-type triterpene saponin EAE epithelial-mesenchymal transition ginseng Ginseng berries ginsenoside ginsenoside CK ginsenoside MT1 ginsenoside Rg3(S) ginsenosides gram unit production hairy root hepatoprotective HMGB1 homology modeling HR-MAS NMR spectroscopy immune system inflammation Lactobacillus ginsenosidimutans M2 polarization macrophage MAPK molecular docking analysis molecular interaction n/a neurogenesis neuroprotection NF-κB notoginseng leaf triterpenes novel glycoside hydrolases ocotillol type ginsenoside epimers Panax ginseng Panax quinquefolium L. Panax sp pharmacopuncture polyploidy polysaccharides primary metabolite pro-resolving protoplast recombinant enzyme Rg3 RORγt safety stereoselective ADME characteristics Th17 transglycosylation UPLC-QTOF/MS wild ginseng |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557766503321 |
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Chen Jen-Tsung
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Computational Approaches: Drug Discovery and Design in Medicinal Chemistry and Bioinformatics
| Computational Approaches: Drug Discovery and Design in Medicinal Chemistry and Bioinformatics |
| Autore | Tutone Marco |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 online resource (387 p.) |
| Soggetto topico |
Chemistry
Research & information: general |
| Soggetto non controllato |
3CL-Pro
3D-QSAR acetylcholinesterase aging progression mechanism Alzheimer's disease aminophenylbenzamide antibody:antigen interactions antivirals binding free energies binding site binding space carbon nanotubes cholesterol computational biology consensus models COVID-19 COX-2 inhibitors deep learning diabetes docking simulations doxorubicin encapsulation drug delivery system drug discovery drug repositioning drug repositioning approaches drug repurposing drug resistance drug-resistance mutations dual mode of action dual-target lead discovery epitope binning epitope mapping epitope prediction FimH fingerprints gene expression signature genome-wide genetic and epigenetic network (GWGEN) glycoprotein D (gD) haeckelite defects HDACs hERG toxicity herpes simplex virus fusion proteins high-throughput virtual screening HIV-2 protease homology modeling hTSPO human dihydrofolate reductase immunoproteasome in silico induced structural deformations induced-fit docking inhibitors isoform-selective histone deacetylase inhibitors isomeric space ligand-based model machine learning main protease MD binding MD simulation metadynamics methotrexate molecular docking molecular dynamics molecular dynamics (MD) simulation molecular dynamics simulation molecular dynamics simulations molecular modeling MRP4 multi-modal multiple-molecule drug multiprotein inhibiting natural compounds multiscale multitargeting mutants Mycobacterium tuberculosis n/a natural compounds neurodegenerative disorders nicotinic acetylcholine receptor non-covalent inhibitors noncovalent interactions oxidative stress PF-00835231 pharmacophore model pharmacophore modeling PK11195 polypharmacology proteasome protein docking protein threading modeling proteomic signature RNA expression regulation SARS-CoV-2 skin aging SNPs sodium-glucose co-transporters 2 Src inhibitors Stone-Wales defects structural bioinformatics structural characterization systems medicine design tuberculosis urinary tract infections uropathogenic bacteria variants virtual screening |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | Computational Approaches |
| Record Nr. | UNINA-9910557519403321 |
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Tutone Marco
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Marine Enzymes : Sources, Biochemistry and Bioprocesses for Marine Biotechnology
| Marine Enzymes : Sources, Biochemistry and Bioprocesses for Marine Biotechnology |
| Autore | Trincone Antonio |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 |
| Descrizione fisica | 1 online resource (378 p.) |
| Soggetto topico |
Biology, life sciences
Research and information: general |
| Soggetto non controllato |
-omics technologies
2-keto-3-deoxy-6-phosphogluconate (KDPG) aldolase 2-keto-3-deoxy-d-gluconate (KDG) kinase 4-deoxy-l-erythro-5-hexoseulose uronic acid (DEH) metabolism adsorption analysis affinity purification algal cell wall degrading enzymes alginate degradation alginate lyase Alginate lyase alginate oligosaccharides alginate-derived products alkaline and cold-adapted dextranase Alteromonas aminophenylboronic acid Antarctic bacterium antioxidant peptides Ascophyllum nodosum asymmetric reduction Bacillus sp. Alg07 Bacteroidetes bifunctional alginate lyase biocatalysts biofilm bioprocesses biorefinery catalytic ability Catenovulum characterization chiral alcohols chitin deacetylase chitooligosaccharides chitosanases cold-adapted cold-adapted enzyme collagen collagenase deacetylation patterns deep sea deep-sea enzyme degradation pattern dental caries detecting endo-fucoidanase Endo-manner enzyme-assisted extraction enzymes error prone PCR esterase expression fermentation optimization Flavobacterium fucoidan galactofucan GH 36 family growing cells heterologous expression high-throughput screening homologous expression homology model homology modeling ichip device inhibitor isomaltoogligosaccharides Isoptericola halotolerans lactose-free milk leucine dehydrogenase marine agent marine bacteria marine bacterium marine biomarkers marine biotechnology marine enzymes marine fungi metalloprotease microalgae microcystin-degrading bacteria molecular docking molecular stabilisation mutation mycotoxin oligosaccharides pCold vector Pectobacterium carotovorum subsp. carotovorum (Pcc) pH-stability PL7 family polyM-specific polysaccharide lyase of family 6 protease Proteobacteria Pseudoalteromonas Pseudoalteromonas sp. KMM 701 purification quorum quenching enzyme resting cells salt-activated enzyme Sargassum mcclurei sea-ice seafood separating Serratia marcescens site-directed mutagenesis Thermo-tolerant transglycosylation Turbinaria ornata Vibrio sp. SY01 Vibrio weizhoudaoensis α-d-galactosidase β-galactosidase |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | Marine Enzymes |
| Record Nr. | UNINA-9910557671503321 |
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Trincone Antonio
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Molecular Biocatalysis 2.0
| Molecular Biocatalysis 2.0 |
| Autore | Křen Vladimír |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 |
| Descrizione fisica | 1 online resource (166 p.) |
| Soggetto topico | Technology: general issues |
| Soggetto non controllato |
"solid-state biocatalysis"
2-ketoglutarate generation abiotic manganese oxides Agaricomycotina amine-reactive phenazine ethosulfate Aspergillus niger Basidiomycota biogenic manganese oxides cell wall anchor cyanide hydratase direct electron transfer E. coli enzyme cascade Fe(II)/2-ketoglutarate-dependent dioxygenase flavin FMO Glide docking glucose oxidase glucose sensor glycemic level monitoring glycosylation sites homology modeling hyaluronic acid hydroxy amino acids in vitro synthesis indigo Lactobacillus plantarum MISO library monooxygenase muramic acid n/a nitrilase nitrile non-reducing carbohydrate one-pot multi-enzyme optimization overproduction periplasm phylogenetic distribution Pseudomonas putida MnB1 quercetin recombinant horseradish peroxidase regio- and stereo-selective synthesis rutin rutinose rutinosidase sequential cascade reaction site-directed mutagenesis substrate docking substrate specificity surface display Talaromyces flavus transglycosylation whole-cell biocatalysis whole-cell biocatalyst α-Hydroxy-β-keto esters β-N-acetylhexosaminidases |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557576703321 |
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Křen Vladimír
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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New Insights into Parvovirus Research
| New Insights into Parvovirus Research |
| Autore | Gallinella Giorgio |
| Pubbl/distr/stampa | MDPI - Multidisciplinary Digital Publishing Institute, 2020 |
| Descrizione fisica | 1 online resource (342 p.) |
| Soggetto topico | Medicine and Nursing |
| Soggetto non controllato |
AAV
AAV2 acute gastroenteritis adeno-associated virus Adeno-associated virus adenoviral vector agricultural pests alpaca anti-cancer antibody interactions antiviral compounds antivirals apoptosis arthropod B19V biocontrol BIRC3 (cIAP-2) bisulfite PCR Bocaparvovirus Bombyx mori bidensovirus brincidofovir canine chapparvovirus canine parvovirus capsid stability Carnivore protoparvovirus 1 caspase-3 cell cycle arrest chapparvovirus children chitin cidofovir circulating angiogenic cells clinical trials combination therapies commercial horse serum coumarin derivatives CpG methylation Cryo-EM densovirus diagnosis dilated cardiomyopathy divalent cations DNA virus endogenous viral elements equine parvovirus-hepatitis erythroid progenitor cells erythrovirus evolution feline panleukopenia virus flavonoids genetics genome genome externalization glycans H-1PV homology modeling horses human airway epithelia human bocavirus human bocavirus 1 hydroxyurea immunomodulation inflammatory cardiomyopathy insect insect parvovirus intravenous immunoglobulin (IVIG) Lepidoptera metagenomics mite myocarditis new viruses next-generation sequencing NS1 NS2 nuclear targeting oncolytic activity oncolytic virus immune therapy oncolytic viruses overlapping promoters Parvoviridae parvovirus parvovirus B19 parvovirus evolution peritrophins phospholipase-A2 phylogeny PLA2 preclinical prognosis protease RACE receptor interactions RNA-seq rodent protoparvoviruses RT-qPCR second generation parvovirus treatments sequence analysis single stranded DNA virus structural biology telbivudine trafficking transcription mapping transcription profile tumor microenvironment uncoating viral communities viral ecology viral metagenomics virus virus diversity virus phylogeny X-ray crystallography |
| ISBN | 3-03928-311-1 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910404088603321 |
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Gallinella Giorgio
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| MDPI - Multidisciplinary Digital Publishing Institute, 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Synthesis of Marine Natural Products and Molecules Inspired by Marine Substances II
| Synthesis of Marine Natural Products and Molecules Inspired by Marine Substances II |
| Autore | Manzo Emiliano |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 online resource (111 p.) |
| Soggetto topico |
Chemistry
Research & information: general |
| Soggetto non controllato |
(−)-majusculoic acid
ADMET animal studies anti-inflammation aureol Avicennia alba biological activity biosynthesis cancer cardiovascular diseases CCK-8 chemical synthesis cyclomarins cyclopeptides divergent total synthesis gag polyprotein homology modeling ilamycins In-silico drug design inflammation LPS malaria marine alkaloids marine natural products molecular dynamics simulation n/a natural products rufomycins tetracyclic meroterpenoids total synthesis tuberculosis virtual screening |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557724503321 |
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Manzo Emiliano
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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