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Anticancer Drugs 2021
| Anticancer Drugs 2021 |
| Autore | Meegan Mary J |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 electronic resource (594 p.) |
| Soggetto topico |
Research & information: general
Chemistry |
| Soggetto non controllato |
thymidylate synthase
cytotoxicity 1,2,3-triazole 1,3,4-oxadiazole 5-fluoruracil pemetrexed docking 3,4'-bis-guanidino 3-amino-4'-guanidino diphenyl ether phenyl pyridyl ether intramolecular hydrogen bond cancer cell viability HL-60 BRAF apoptosis thieno[2,3-d][1,2,3]triazine acetamide H1299 HER2 EGFR Bcl-2 inhibitors Indole-based analogues benzimidazole MTT cytotoxic assay cell cycle analysis DNA fragmentation ELISA solid/lipid nanoparticles phenstatin letrozole tubulin polymerisation inhibitor aromatase inhibitor breast cancer hybrid molecule dual-targeting molecule designed multiple ligand NaMSA cyclophosphamide histopathology testis urinary bladder anticancer agents enantioselective synthesis gastric adenocarcinoma tryptophanol concentration-guided dosing model informed dosing physiologically based pharmacokinetics sorafenib tyrosil-DNA-phosphodiesterase 1 adamantane resin acid TDP1 cytotoxic agents apoptosis induction HT-29 cells MDA-MB-231 cells mechanism prediction STAT inhibitors miR-21 hydrazide derivatives nitrogen scaffolds mitoxantrone cardiotoxicity inflammation oxidative stress age cumulative dose Trk NTRK tissue-agnostic larotrectinib entrectinib Trk fusion protein kinase inhibitors USFDA cancer patent review generic product doxazosin MD simulations combretastatin A-4 cytotoxic activity hybrid compounds indazole mucin MUC1 MUC16 immunotherapy cancer vaccine CAR (chimeric antigen receptor) ADC (antibody-drug conjugate) thiourea interleukin-6 trypan blue assay chalcones exportin-1 covalent binding CovDock anticancer activity xanthone in vitro in vivo isolation synthesis heterocyclic compound benzenesulfonamides imidazoles alkylated colony formation tumor spheroids HDAC inhibitors chalcone dual inhibitors carvedilol kidney toxicity 7-deaza-4'-thioadenosine derivatives multi-kinase inhibitor anticancer nucleoside Imiquimod drug efflux multidrug resistance Toll-Like Receptor |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910576874303321 |
Meegan Mary J
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Biological and Pharmacological Activity of Plant Natural Compounds
| Biological and Pharmacological Activity of Plant Natural Compounds |
| Autore | Pezzani Raffaele |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 electronic resource (296 p.) |
| Soggetto topico | Medicine |
| Soggetto non controllato |
natural products
phenylpropanoids phenolic acids plants depression behavioral disorders forced swim test tail suspension test anti-cancer activities multifloroside 10-oxyderivatives of oleoside secoiridoids structure-activity relationship flow cytometry epigallocatechin-3-gallate EGCG catechin green tea cancer preventive pharmacological activities Amelanchier alnifolia Nutt carriers powders bioactive compounds functional food Ageratina havanensis flavonoids UPLC-ESI-MS/MS P-glycoprotein antioxidant potential nootkatone anti-inflammatory acute inflammation granuloma Pharbitis nil colorectal cancer KRAS muscle function juglone NLRP3 inflammasome caspase-1 IL-1β IL-18 plant secondary metabolites natural compounds biological activity phytochemistry pharmacological activity plant side effects Talisia esculenta Brosimum gaudichaudii Genipa americana Bromelia antiacantha RA-3 nephrotoxicity triterpene antioxidant hyperuricemia Hibiscus acetosella phenolic compound antibacterial UPLC Tabebuia impetiginosa Taheebo traditional uses immunopharmacology immunological disorders hesperidin new-clean process extraction nanocrystals anti-ageing zingerone lipopolysaccharide inflammation anti-oxidant cytokine storm procalcitonin histopathology doxorubicin Mahonia aquifolium matrix metalloproteinases cytotoxicity human lung adenocarcinoma |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557471303321 |
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Pezzani Raffaele
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Biological and Pharmacological Activity of Plant Natural Compounds II
| Biological and Pharmacological Activity of Plant Natural Compounds II |
| Autore | Pezzani Raffaele |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 electronic resource (338 p.) |
| Soggetto topico |
Medicine
Pharmacology |
| Soggetto non controllato |
Bergenia species
botanical description traditional uses phytochemistry pharmacology anti-urolithiatic activity bergenin Flaxseed oil linusorb B3 anti-cancer apoptosis actin polymerization Src glioblastoma chlorogenic acid coffee cyclooxygenase espresso instant coffee platelet aggregation Rubia tinctorum L. antioxidants polyphenols ethylene glycol urolithiasis histophatology Saccharomyces cerevisiae β-glucan antimicrobial and anticancer activities detoxification ability immunomodulatory effect Aquilaria sinensis pheophorbide A MMP-2 MMP-9 HT-1080 advanced glycation end product (AGE) oxidative stress epithelial to mesenchymal transition AGE-inhibitor swertiamarin diabetic nephropathy astragaloside IV Astragalus membranaceus huang qi Astragali Radix liver liver regeneration 70% partial hepatectomy proliferation rat memory object recognition Ginkgo biloba dorsal hippocampus formation brain-derived neurotrophic factor Diclofenac γ-lactone nano-emulsion methylcellulose Ostrich oil Struthio camelus Caenorhabditis elegans leaf extract neuroprotection antioxidant activity DAF-16 Clerodendrum infortunatum terpenoids phenylpropanoids antidiabetic breast cancer Combretum indicum L. antidiabetic activity histopathology UPLC-QTOF/ESI-MS network pharmacology Biebersteinia heterostemon galegine hypotensive toxicity Sage Salvia officinalis cytotoxicity hepatoprotection MDA TAOxC MCF-7 HeLA cells HepG-2 cells Peganum harmala anti-inflammatory activity antioxidant LC-ESI-MS/MS traditional medicine rheumatoid arthritis rosmanol carnosol Callicarpa longissima TLR4/NF-κB/MAPK synergistic effect diabetes mellitus anti-diabetic drugs monoterpenes |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910566486603321 |
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Pezzani Raffaele
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Cellular and Molecular Mechanisms of Nephropathic Cystinosis
| Cellular and Molecular Mechanisms of Nephropathic Cystinosis |
| Autore | Levtchenko Elena N |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 electronic resource (230 p.) |
| Soggetto topico |
Medicine
Pharmacology |
| Soggetto non controllato |
cystinosis
cysteamine bone osteoclast genotype CD34+ hematopoietic stem and progenitor cells gene therapy pre-clinical studies investigational new drug application clinical trial disulfiram mice zebrafish fertility azoospermia hypogonadism histopathology mouse model lysosomal storage disease cell and animal models infantile nephropathic cystinosis bone-muscle wasting fibroblast growth factor 23 osteoclasts sclerostin leptin fractures nephropathic cystinosis hollow fiber membrane 3-dimensional models autophagy macrophages inflammasome proximal tubular cells endocytosis apoptosis chitotriosidase interleukins galectin-3 novel therapies endolysosome epithelial cell differentiation homeostasis lysosomal storage diseases mitochondrial distress kidney proximal tubule programmed cell death central nervous system cortical atrophy arterial spin labelling cystine blood level lysosomal storage disorder history treatment strategies for cystinosis newborn screening clinical course CTNS-pathogenic variants newborn screening for cystinosis kidney progenitors cell model biomarkers cystine kidney therapeutic monitoring |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910585941103321 |
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Levtchenko Elena N
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Diagnostic or Therapeutic Strategies for Pregnancy Complications
| Diagnostic or Therapeutic Strategies for Pregnancy Complications |
| Autore | Heazell Alexander |
| Pubbl/distr/stampa | Basel, : MDPI Books, 2022 |
| Descrizione fisica | 1 electronic resource (238 p.) |
| Soggetto topico | Medicine |
| Soggetto non controllato |
ultrasonography
elastography uterine cervix term pregnancy parturition genotyping preeclampsia MMP-9 MMP-2 SNPs tocolytic preterm birth preterm labor neonate prematurity pregnancy therapeutic progesterone fetus sex as a biological variable sex differences pregnancy complications placenta prenatal diagnosis fetal growth restriction miscarriage chorio-deciduitis grade amnionitis acute histologic chorioamnionitis intra-amniotic inflammatory response beta-blocker endothelial dysfunction cardiovascular disease pregnancy loss immunology vascular endothelial growth factor galectin-9 interleukin-4 proteomics urine biomarkers IBP4 SHBG RPL NK cells sildenafil PDE5A VEGF-A angiotensin infant newborn female abruptio placentae Apgar score pregnant women gestational age IL-1 blockade anakinra canakinumab human inflammation fetal growth restriction (FGR) intra-uterine growth restriction (IUGR) SPINT1 HAI-1 stillbirth placental insufficiency histopathology cardiovascular risk postpartum screening |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910595070803321 |
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Heazell Alexander
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| Basel, : MDPI Books, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Family Iridoviridae Molecular and Ecological Studies of a Family Infecting Invertebrates and Ectothermic Vertebrates
| Family Iridoviridae Molecular and Ecological Studies of a Family Infecting Invertebrates and Ectothermic Vertebrates |
| Autore | Chinchar Gregory |
| Pubbl/distr/stampa | MDPI - Multidisciplinary Digital Publishing Institute, 2019 |
| Descrizione fisica | 1 electronic resource (234 p.) |
| Soggetto non controllato |
risk assessment
CQIV mathematical models amphibian iridovirus ISDL Exopalaemon carinicauda viral load virus isolation European chub outbreak Unconventional T cell early detection susceptible species viral immune evasion DNA virus Rana grylio virus antibody intracellular localization Rana grylio virus (RGV) British Columbia Iridoviridae Andrias davidianus ranavirus viral infection susceptible-infected (SI) models yeast two-hybrid (Y2H) prevalence host-pathogen interactions Pacific herring Procambarus clarkii Bayesian inference eDNA amphibians Artemia spp ranavirosis cross-species transmission FV3 SHIV Gryllus bimaculatus Pacific salmon NF-?B cricket IIV-6 virus binding erythrocytic necrosis virus (ENV) envelope protein iridovirus core proteins emerging infection host Ranavirus white head Rana temporaria Imd biosecurity antiviral immunity Decapodiridovirus endemic disease Macrobrachium rosenbergii co-immunoprecipitation (Co-IP) Common frog aquatic animals virus surveillance immunomodulators frog virus 3 ELISA DIV1 megalocytivirus Lymphocystis disease virus bearded dragon susceptibility protein interaction Pogona vitticeps viral erythrocytic necrosis (VEN) histopathology epidemiology native-fish conservation viral transmission Sparus aurata immunohistochemistry lizard disease dynamics immunofluorescence transmission modelling Macrobrachium nipponense interferon nonclassical MHC heparan sulfate ranavirus Mexico |
| ISBN | 3-03921-517-5 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910367754803321 |
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Chinchar Gregory
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| MDPI - Multidisciplinary Digital Publishing Institute, 2019 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Histopathology of Aquatic Animals
| Histopathology of Aquatic Animals |
| Autore | Berillis Panagiotis |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 electronic resource (166 p.) |
| Soggetto topico |
Research & information: general
Biology, life sciences Fisheries & related industries |
| Soggetto non controllato |
micro-nano plastics
fish organism model histopathology blood biomarkers microlipoma liver Barbus balcanicus 3D reconstruction nutrition aquaculture fishmeal replacement land animal proteins histology intestinal microbiota Sparus aurata toxicity effect invertebrate mussels Aeromonas spp rainbow trout bacteria infection antinutritional factors soybean gut health environmental monitoring histopathological biomarkers histopathological alterations fish gills atrazine Purkinje cerebellum myocytes toxicology IP3Rs Vistonis Lake physico-chemical parameters gills HSPs MARKs Na+-K+ ATPase hepatorenal pathology toxicosis biomarkers adult Xenopus laevis |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910576876403321 |
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Berillis Panagiotis
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Honey Bee Health
| Honey Bee Health |
| Autore | Cilia Giovanni |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 electronic resource (311 p.) |
| Soggetto topico | Research & information: general |
| Soggetto non controllato |
text-mining
topic modeling colony collapse disorder genomics Varroa mite honey bee health Apis mellifera GABA beta-alanine oxalic acid diet effect microbiota bee silicone band hive passive sampler honey bee virus DWV-A hive products honey pollen wax Nosema ceranae Nosema apis epidemiology replacement ecoregions North Asia DNA analysis health Lotmaria passim Melissococcus plutonius pathology Tropilaelaps Varroa destructor honey bees mites viruses behavior social immunity Africanized bees microsatellites Uruguay honeybee One-Health nexus landscape beekeeper pathogens histopathology testes microsporidia Hsp70 gene 16S rRNA gene garlic viability prevalence infection intensity seasonality bee longevity bee population honey stores CCD mite reproductive rate worker brood infestation level longevity distribution model honey bee model grooming drones chronic bee paralysis virus Varroa infestation control nosemosis hairless black syndrome honeybee veterinary medicine acute bee paralysis chronic bee paralysis deformed wing virus varroa infestation honey bee losses viral diseases nosematosis negative pressures bee hive monitoring real-time monitoring sound measurement swarming detection queen bee detection sound analysis acaricides primer pheromone hydrocarbon profiles survival Nosema disease dark forest bee Apis mellifera mellifera microsatellite loci association gut microbiota gut mycobiota season Apis mellifera L. unicellular |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557317503321 |
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Cilia Giovanni
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Image Processing Using FPGAs
| Image Processing Using FPGAs |
| Autore | Bailey Donald |
| Pubbl/distr/stampa | MDPI - Multidisciplinary Digital Publishing Institute, 2019 |
| Descrizione fisica | 1 electronic resource (204 p.) |
| Soggetto non controllato |
nuclei detection
System-on-Chip FPGA K-Means hardware acceleration image analysis perceptual coding line buffer heterogeneous computing window filters processor architectures hardware accelerators stream processing embedded systems image processing pipeline image processing generalized Laplacian of Gaussian filter background estimation real-time systems FPGA implementation hardware architecture compression image borders memory zig-zag scan histopathology just-noticeable difference (JND) memory management downsampling image segmentation feature extraction design mean Shift clustering high-throughput segmentation streaming architecture power D-SWIM hardware/software co-design high-level synthesis contrast masking texture detection pipeline field programmable gate array (FPGA) JPEG-LS low-latency connected components analysis luminance masking field programmable gate arrays (FPGA) |
| ISBN | 3-03897-919-8 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910346693003321 |
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Bailey Donald
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| MDPI - Multidisciplinary Digital Publishing Institute, 2019 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Mycotoxin Exposure and Related Diseases
| Mycotoxin Exposure and Related Diseases |
| Autore | Viegas Susana |
| Pubbl/distr/stampa | MDPI - Multidisciplinary Digital Publishing Institute, 2020 |
| Descrizione fisica | 1 electronic resource (222 p.) |
| Soggetto non controllato |
metagenomic sequencing
total diet study risk assessment lipids Poultry fumonisin B1 triiodothyronine Transcriptome Kashin-Beck disease phospholipids intestinal microbiome mycotoxin binding pre-pubertal gilts children Fusarium mycotoxins co-contamination food consumption urinary biomarkers mitigation Aflatoxin M1 HPLC analysis absorption liver Cecum limit of detection Cecal Tonsil yeast cell wall extracts modelling swine production Turkey Fab' fumonisins blood serum broilers affinity microbiota asymmetric Mach-Zehnder interferometer biomonitoring zearalenone doses mycotoxins clinical chemistry histopathology HT-2 toxin occupational exposure Vietnam aflatoxin B1 piglet cytotoxicity public health ochratoxin A oxidation T-2 toxin RNAseq intestinal mycobiome optical biosensors modified HSCAS lab-on-chip Lactobacillus casei Shirota mycotoxins mixture feed prevalence and safety Aflatoxin B1 Alloprevotella |
| ISBN | 3-03928-705-2 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910404083903321 |
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Viegas Susana
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| MDPI - Multidisciplinary Digital Publishing Institute, 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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