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Computational and Experimental Approaches in Multi-Target Pharmacology
| Computational and Experimental Approaches in Multi-Target Pharmacology |
| Autore | Anastasio Thomas J |
| Pubbl/distr/stampa | Frontiers Media SA, 2017 |
| Descrizione fisica | 1 online resource (122 p.) |
| Collana | Frontiers Research Topics |
| Soggetto topico | Pharmacology |
| Soggetto non controllato |
computer modeling
drug combination drug discovery drug repurposing high throughput screening multidrug therapeutics multifactorial process polypharmacy synergy systems biology |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910261143503321 |
Anastasio Thomas J
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| Frontiers Media SA, 2017 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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From Basic Research to New Tools and Challenges for the Genotoxicity Testing of Nanomaterials
| From Basic Research to New Tools and Challenges for the Genotoxicity Testing of Nanomaterials |
| Autore | FESSARD Valérie |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 online resource (188 p.) |
| Soggetto topico |
Humanities
Social interaction |
| Soggetto non controllato |
3D culture
advanced in vitro model AgNP Allium cepa aluminum antioxidant activity apoptosis BEAS-2B cells CeO2NP comet assay cytotoxic cytotoxicity DNA damage DNA methylation epigenetics FPG enzyme genotoxic genotoxicity graphene oxide gut hepatotoxicity HepG2 high throughput screening Hprt Hs27 human fibroblasts human amniotic cells in vitro genotoxicity in vitro testing lincomycin liver liver spheroids metal oxides metal/coating agent ratio micronuclei formation micronucleus micronucleus assay multi-walled carbon nanotubes (MWCNT) n/a nanomaterial nanoparticles nanoplastics nanotoxicology nongenotoxic silver nanoparticles oral route oxidative stress polystyrene nanoparticles reduced graphene oxide safer-by-design silver ions SiO2NP TiO2NP titanium dioxide nanoparticles tritiated particles tungsten V79 cells ZnONP |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557414003321 |
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FESSARD Valérie
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Mechanisms of ER Protein Import
| Mechanisms of ER Protein Import |
| Autore | Zimmermann Richard |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 online resource (258 p.) |
| Soggetto topico |
Biology, life sciences
Research and information: general |
| Soggetto non controllato |
bimolecular luminescence complementation
chaperones co-translational translocation competition contact sites cyclotriazadisulfonamide differential protein abundance analysis DNAJC3 EMC endoplasmic reticulum ER protein translocase ER quality control ER translocon ER-SURF fidelity folding GET high throughput screening hydrophobicity inhibitor insertion label-free quantitative mass spectrometry lipid droplets membrane extraction membrane insertion membrane protein membrane protein insertion membrane proteins mitochondria molecular docking molecular dynamics simulations molecular modelling n/a NAC nascent peptide chain nascent polypeptide-associated complex peroxisomes PEX3 positive-inside rule preprotein protein targeting protein translocation protein transport protein-protein interactions ribosome ribosome stalling Sec61 Sec61 complex Sec61 dependent translocation Sec61 translocase Sec61 translocon Sec62 Sec63 signal peptidase signal peptide signal recognition particle signal recognition particle dependent protein targeting signal sequence SND split luciferase SRP synthetic peptide complementation translocon transmembrane helix transmembrane segment TRAP complex Zellweger syndrome |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910576886203321 |
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Zimmermann Richard
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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