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New Insights in the Genetics and Genomics of Adrenocortical Tumors and Pheochromocytomas
| New Insights in the Genetics and Genomics of Adrenocortical Tumors and Pheochromocytomas |
| Autore | Igaz Peter |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 electronic resource (272 p.) |
| Soggetto topico | Medicine |
| Soggetto non controllato |
pheochromocytoma
paraganglioma genetics non-coding RNA malignancy biomarker treatment adaptive metabolism adrenal gland conn adenoma fatty acid metabolism ferroptosis hyperaldosteronism metabolic reprogramming β-oxidation PPARα tumor microenvironment Next Generation Sequencing hereditary cancer endocrine tumor syndrome KCNJ5 somatic mutation pulse wave velocity aldosterone-producing adenoma adrenalectomy propensity score matching arterial stiffness pheochromocytomas paragangliomas mutations susceptibility genes driver mutations hereditary germline somatic environment variants tumor suppressor genes metastatic RNAseq next generation sequencing adrenocortical carcinoma in silico analysis machine learning bioinformatic clustering biomarker prediction aldosterone producing adenoma ATP2B3 K416-F418delinsN mutation primary aldosteronism PPGL telomeres TERT ATRX NOP10 prognostic biomarker ALT phaeochromocytoma cancer mitochondrial complex II zebrafish therapy drug discovery redox balance pathway Vitamin C mitotane H295 strains microRNA aldosterone circulating adrenocortical transcriptomics epigenetics metabolomics epidemiology genetic analysis mortality surveillance TP53 R337H genetic testing adrenocortical tumor neonatal screening screening adenoma adrenal tissue artificial intelligence neural network |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557609003321 |
Igaz Peter
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Pheochromocytoma (PHEO) and Paraganglioma (PGL)
| Pheochromocytoma (PHEO) and Paraganglioma (PGL) |
| Autore | Pacak Karel |
| Pubbl/distr/stampa | MDPI - Multidisciplinary Digital Publishing Institute, 2019 |
| Descrizione fisica | 1 electronic resource (380 p.) |
| Soggetto non controllato |
polycythemia
peptide receptor radiotherapy vasculogenesis catecholamines neuroendocrine GTV adaptive immunity therapy resistance histology transgenic mice cryoablation spheroids energy metabolism somatostatinoma angiogenesis pheochromocytoma SDHD percutaneous ethanol injection metanephrines SDHB global longitudinal strain mutation normetanephrines catecholamine PASS PGL 177Lu-DOTATATE chromosomal alteration speckle-tracking echocardiography lL-6 dog percutaneous ablation stem-like tumor cells EPAS1 neural crest fluorescence imaging neutrophil xenograft inflammation head and neck weighted standard deviation FGF21 calorimetry HIF average real variability next-generation sequencing adrenocortical carcinoma carotid body hypoxia-inducible factor paraganglioma succinate dehydrogenase blood pressure variability arrhythmia mortality NF1 toll-like receptor GAPP NET subclinical systolic dysfunction pheochromocytoma and paraganglioma PET-CT pan-cancer analysis mouse pheochromocytoma cells innate immunity neurogenesis neuroendocrine tumor obesity hypotension hypoxia CNV detection 18F-FDOPA comparative genomics adrenomedullary function PCC pathogen-associated molecular patterns adrenal tumor radiotherapy 11C-hydroxy-ephedrine radiofrequency ablation PPGL minimally invasive procedure sporadic diabetes mellitus adrenal incidentaloma germline mutation immunotherapy VHL immunohistochemistry metastatic OR malignant pheochromocytoma erythropoietin postoperative targeted therapy PRRT metastatic mitochondria T cell TCA cycle meta-analysis pseudohypoxia ectopic secretion radiosensitization chromogranin A hereditary hypertension PET phosphorylation tyrosine hydroxylase |
| ISBN | 3-03921-655-4 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | Pheochromocytoma |
| Record Nr. | UNINA-9910367743903321 |
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Pacak Karel
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| MDPI - Multidisciplinary Digital Publishing Institute, 2019 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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