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Advances in DNA Vaccines
| Advances in DNA Vaccines |
| Autore | Isaguliants Maria |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 electronic resource (210 p.) |
| Soggetto topico |
Medicine
Epidemiology & medical statistics |
| Soggetto non controllato |
alphaviruses
layered RNA/DNA vectors DNA vaccines RNA replicons recombinant particles tumor regression protection against tumor challenges and infectious agents ebola virus disease artificial T-cell antigens DNA vaccine constructs computer design gene expression immunogenicity DNA vaccine mRNA vaccine plasmid DNA in vitro transcribed mRNA immune responses formulations Cytolytic T Lymphocytes antibodies innate immunity adjuvants vaccine delivery plasmid cytolytic perforin bicistronic HCV HIV IL-36 adjuvant DNA Zika Epstein-Barr virus latent proteins LMP2 EBNA1 LMP1 HIV-1 enhancer element circovirus influenza immunization intranasal lipid flagellin BCG vaccine rBCG HTI T-cell AIDS clinical trial therapeutic vaccine hepatitis C virus (HCV) mesenchymal stem cells (MSC) modified MSC DNA immunization nonstructural HCV proteins immune response HCV vaccine myeloid derived suppressor cells (MDSCs) |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557354503321 |
Isaguliants Maria
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Chronic HCV Infection: Clinical Advances and Eradication Perspectives
| Chronic HCV Infection: Clinical Advances and Eradication Perspectives |
| Autore | Liberto Maria Carla |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 electronic resource (104 p.) |
| Soggetto topico |
Medicine
Epidemiology & medical statistics |
| Soggetto non controllato |
HCV
rheumatic interferon mortality hepatitis C virus (HCV) phylogeny resistance-associated substitution (RAS) chronic hepatitis C vibration controlled transient elastography fibrosis steatosis hepatocellular carcinoma hepatitis C genotype 3 liver cirrhosis pangenotypic children ledipasvir/sofosbuvir real-life sustained virological response elimination model COVID-19 PWID homeless persons HCV eradication direct-acting antivirals out-of-hospital retention in care |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | Chronic HCV Infection |
| Record Nr. | UNINA-9910557608603321 |
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Liberto Maria Carla
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Targeting STAT3 and STAT5 in Cancer
| Targeting STAT3 and STAT5 in Cancer |
| Autore | Moriggl Richard |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 |
| Descrizione fisica | 1 electronic resource (578 p.) |
| Soggetto topico |
Research & information: general
Biology, life sciences |
| Soggetto non controllato |
multiple myeloma
STAT3 S3I-1757 nanoparticle CD38 siRNA/RNAi polyethylenimine PEI lipopolyplex siRNA delivery glioma glioblastoma STAT5 AKT ERK1/2 prolactin androgens prostate cancer knockout escape mechanisms stem/progenitor cells cell hierarchy cancer CD4+ T cells CD8+ T cells myeloid cells immune check point hepatitis C virus (HCV) cirrhosis hepatocellular carcinoma (HCC) endoplasmic reticulum (ER) stress oxidative stress (OS) unfolded protein response (UPR) microRNA-122 (miR-122) nuclear factor erythroid 2-related factor 2 (NRF2) signal transducer and activator of transcription 3 (STAT3) hepatocyte nuclear factor 4 alpha (HNF4A) solid cancers cell cycle apoptosis inflammation mitochondria stemness tumor suppression melanoma autoimmune disease immunotherapy tumor-immune cell interactions breast cancer PD-L1 M2 macrophages NK cells STAT3 inhibitor XIII hedging transaction costs dynamic programming risk management post-decision state variable cancer progression cancer-stem cell cytokine therapy resistance metastasis immunosuppression tumor microenvironment proliferation tyrosine kinase 2 JAK family of protein tyrosine kinases signal transducer and activator of transcription cytokine receptor signaling gain-of-function mutation tumorigenesis ADAM17 interleukin-6 trans-signaling epidermal growth factor receptor (EGF-R) shedding metalloprotease tumor necrosis factor alpha (TNFα) inflammation associated cancer colon cancer lung cancer SH2 domain mutations autosomal-dominant hyper IgE syndrome inflammatory hepatocellular adenomas T-cell large granular lymphocytic leukemia T-cell prolymphocytic leukemia growth hormone insensitivity syndrome nuclear pore complex nuclear transport receptors nucleocytoplasmic shuttling targeting tumor-associated macrophages adoptive T cell therapy immune suppression STAT transcription factors JAK STAT T-PLL T-cell leukemia meta-analysis STAT5B signaling small-molecule inhibitors cancer models companion animals comparative oncology pharmacological inhibitor STAT5 signaling chemotherapy resistance myeloid leukemia heat shock proteins chaperones stabilization targeted therapy ovarian cancer hematopoietic cancers therapeutic targeting pharmacological inhibitors mTOR Bone Marrow Failure Syndromes lymphocytes lymphoma T-cells RHOA NGS MPN JAK2 V617F neoplastic stem cells |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557623503321 |
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Moriggl Richard
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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