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Monoclonal Antibodies and Their Functional Fragments in Research, Diagnosis and Therapy
| Monoclonal Antibodies and Their Functional Fragments in Research, Diagnosis and Therapy |
| Autore | Ruvo Menotti |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 electronic resource (278 p.) |
| Soggetto topico | Technology: general issues |
| Soggetto non controllato |
porcine deltacoronavirus
nucleocapsid monoclonal antibodies neurodegenerative disorders affibody molecules blood–brain barrier receptor-mediated transcytosis transferrin receptor AL amyloidosis CD38 anti-CD38 MoAb Daratumumab Isatuximab myeloma BCMA bispecific T-cell engager antibody-drug conjugates chimeric antigen receptor T-cells belantamab mafodotin idecabtagene vicleucel JNJ-68284528 Mabs Antibody-Drug Conjugate cancer therapy drug targeting payload cross-linking antibody fragment Fab scFv E. coli YKL-40 CHI3L1 monoclonal antibody phage display lung metastasis prostate-specific membrane antigen in vivo imaging prostate cancer glutamate carboxypeptidase II NAALADase immunization antibody protocol guinea pig cDNA chimeric antigen receptor (CAR T) universal CAR T modular CAR T universal immune receptor CAR adaptor adoptive immunotherapy split CAR bispecific polyspecificity pharmacokinetics solubility aggregation viscosity developability stability affinity specificity protein engineering self-association non-specific binding immunogenicity antibody fragments single chain amyloid oligomer neurotoxicity NUsc1 |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557613003321 |
Ruvo Menotti
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Refinements to Animal Models for Biomedical Research
| Refinements to Animal Models for Biomedical Research |
| Autore | Musk Gabrielle |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 electronic resource (234 p.) |
| Soggetto topico |
Research & information: general
Biology, life sciences |
| Soggetto non controllato |
mouse
blood sample well-being retrobulbar submandibular sublingual functional MRI rat anaesthesia refinement calves disbudding gene transcription cytokines pain meloxicam nCounter guinea pig Cavia porcellus captive bolt humane euthanasia laboratory animal humane killing piglet castration behaviour peri-operative vocalisation nociception neonate anaesthesia analgesia sheep survey preclinical research health nociceptive threshold horse cat dog camel 3R principles transdermal fentanyl patch grimace scores laboratory animals pain assessment rabbit postoperative analgesia facial expressions grimace scales mice rat animal research animal testing biomedical research history of science |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557128603321 |
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Musk Gabrielle
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Zika Virus and Host Interactions
| Zika Virus and Host Interactions |
| Autore | Hobman Tom |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 electronic resource (256 p.) |
| Soggetto topico |
Research & information: general
Biology, life sciences |
| Soggetto non controllato |
Zika virus
peroxisomes innate immune response interferon astrocytes fetal brain zika virus flaviviruses T cells host-pathogen interactions flavivirus tight junctions claudins ZO-1 blood-placental barrier placenta apoptosis viral replication Bcl-2 protein family ZIKV virus host interactions pathogenesis MR766 guinea pig subcutaneous vaginal sexual transmission virus transmission envelope protein glycosylation fusion loop viral fusion cell entry NS5 protein nuclear localization inflammation innate immunity extracellular vesicles cellular communication C6/36 cells human monocytes endothelial vascular cells protein–protein interaction non-structural viral proteins network JAK/STAT cytokine West Nile virus HSP90 NS5 virus–host interactions anti-viral signaling immune response inflammatory mediator Sertoli cells Leydig cells ZIKA virus arboviruses infertility IFN RIG-I MDA5 IFNAR1 zika host cell death peroxisome mosquito tight junction |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557297503321 |
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Hobman Tom
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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