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Clay-Based Pharmaceutical Formulations and Drug Delivery Systems
| Clay-Based Pharmaceutical Formulations and Drug Delivery Systems |
| Autore | Viseras César |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 electronic resource (202 p.) |
| Soggetto topico | Medicine |
| Soggetto non controllato |
hydrochlorothiazide
cyclodextrins sepiolite nanoclay dissolution rate tablet electrospinning chitosan chondroitin sulfate scaffolds montmorillonite halloysite fibroblasts proliferation immune response glycosaminoglycans antimicrobial properties palygorskite spring water hydrogel fibroblast biocompatibility wound healing mesoporous clay Neusilin aeroperl liquisolid technique glyburide dissolution improvement hydrotalcite ketoprofen hybrid photostability hydrogel film bioadhesion heavy metal hazardous element element mobility clay minerals toxicity palygorksite proliferation Franz cell bioactive elements praziquantel drug organic solvents in vitro dissolution tests cytotoxicity targeted drug delivery halloysite nanotube osteosarcoma methotrexate surface modification |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557129803321 |
Viseras César
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Looking Forward to the Future of Heparin: New Sources, Developments and Applications
| Looking Forward to the Future of Heparin: New Sources, Developments and Applications |
| Autore | Fareed Jawed |
| Pubbl/distr/stampa | MDPI - Multidisciplinary Digital Publishing Institute, 2018 |
| Descrizione fisica | 1 electronic resource (282 p.) |
| Soggetto non controllato |
alginate
edema Heparin Red solid lipid nanoparticles Fe3O4·DA-BSA/HA dermatan sulfate sulfated alginate porcine heparin theranostics low-molecular-weight heparin Arixtra® biomaterials hepcidin ovarian cancer iron oxide nanoparticles heparin-induced thrombocytopenia bone morphogenetic protein (BMP) hyaluronic acid (HA) crude heparin platelets resistance sclerostin LMWH gremlin low molecular weight heparin (LMWH) low molecular weight glycosaminoglycans human plasma single crystal X-ray structure iron homeostasis noggin super paramagnetic iron oxide nanoparticles (SPION) manufacturing methods paclitaxel (PTX) brain injury bovine heparin inflammation qNMR antithrombin reference standard quantitative NMR enoxaparin danaparoid sodium NMR GDNF orthogonal multi-analytical methods ternary complex heparan sulphate serglycin bovine serum albumin (BSA) HSQC recombinant expression heparin heparin oligosaccharides functional assay BMP antagonists intestinal lymphatic absorption size exclusion chromatography heparin coating diagnosis bioreactor anemia proteoglycan heparin process PCA chemometric fluorescent probe pharmacopeia affinity chromatography component quantitative analysis Fondaparinux sodium perylene diimide dyes thrombin inhibition extended physicochemical characterization cisplatin glycosaminoglycans TGF-? chondroitin sulfate dalteparin sequence and compositional investigations molecular weight magnetic resonance imaging (MRI) industrial LC-MS iduronic acid conformation heparan sulfate growth and differentiation factor (GDF) assay subarachnoid hemorrhage |
| ISBN | 3-03842-950-3 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | Looking Forward to the Future of Heparin |
| Record Nr. | UNINA-9910346841803321 |
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Fareed Jawed
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| MDPI - Multidisciplinary Digital Publishing Institute, 2018 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Marine Compounds and Cancer 2020
| Marine Compounds and Cancer 2020 |
| Autore | Honecker Friedemann |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 electronic resource (480 p.) |
| Soggetto topico | Medicine |
| Soggetto non controllato |
apoptosis
fucoidan hepatocellular carcinoma reactive oxygen species 3-alkylpyridinium polymers nicotine nicotinic acetylcholine receptor non-small cell lung carcinoma melanoma sinulariolide proteomic mitochondria caspase cascade marine fungus sediment anthranilic acid Penicillium paneum cytotoxicity dibromotyrosine mitochondrial dysfunction oxidative stress topoisomerase epigonal organ bonnethead shark Jurkat tumor cell line hippuristanol PEL AP-1 STAT3 Akt colorectal cancer marine mollusc brominated indoles shrimp chemoprevention fatty acids carotenoids cancer nanoparticle osteosarcoma lung metastasis elisidepsin lipid rafts hydroxylated lipids fatty acid 2-hydroxylase cooperative binding membrane permeabilization marine organisms polysaccharides anticancer anticarcinogenic mechanisms of action fumigaclavine C anti-proliferation mitochondrial pathway anti-cancer anti-proliferative carotenoid cell cycle arrest fucoxanthin azoxymethane bioactive natural product isatin in vivo model Marthasterias glacialis L. palmitic acid ER-stress CHOP Antibody Drug Conjugates (ADCs) marine antitumor agents clinical trials approved antitumor agents AD0157 angiogenesis marine drug pyrrolidinedione secondary metabolites cancer preventive chemopreventive trabectedin plitidepsin tumor-associated macrophages tumor microenvironment preclinical anticancer immunity antiangiogenesis fascaplysin cyclin-dependent kinase small cell lung cancer camptothecin poly(ADP-ribose)-polymerase inhibitor breast cancer seaweed therapeutic compounds autophagy marine drugs autophagy inhibitors autophagy inducers macrolide programmed cell death energy stress araguspongine C c-Met HER2 gemcitabine pazopanib phase I safety soft tissue sarcoma pachastrissamine jaspine B carbocyclic analogue sphingosine kinase inhibitor molecular modeling ET-743 DNA minor groove binder soft tissue sarcoma chemotherapy bis (2,3-dibromo-4,5-dihydroxy-phenyl)-methane (BDDPM) anti-metastatic activity cell adhesion β1-integrin FAK BEL-7402 cell triterpene glycosides sea cucumbers antitumor activities arrest of cell cycle antibacterial marangucyclines deep-sea Streptomyces sp. SCSIO 11594 LS-1 SNU-C5/5-FU TGF-β signaling carcinoembryonic antigen kalkitoxin Moorea producens mitochondria toxin VEGF angiogenesis inhibitor hypoxia-inducible factor-1 HIF-1 Lyngbya majuscula marine metabolites SZ-685C nonfunctioning pituitary adenomas Ecklonia cava phlorotannins dieckol migration sipholenol A ABC transporter multidrug resistance P-gp/ABCB1 BCRP/ABCG2 MRP1/ABCC1 marine natural products glioblastoma xyloketal B proliferation TRPM7 marine compound ribosomal protein genes snoRNA FAU RPS30 SNORA62 evolution Porifera Penicillium brevicompactum Brevianamide Mycochromenic acid derivative antifouling Caribbean sponge plakortide endoperoxide leukemia multi-drug resistant leukemia Sarcophyton ehrenbergi soft coral terpenes cembranoids cytotoxic activity molecular docking uveal melanoma oxidative stress virtual screening Topo I inhibitor low toxic natural product Ulva fasciata selenium-containing polysaccharide-protein complex pseudopterosin NF-κB p65 inflammation cytokine release IL-6 TNFα MCP-1 glucocorticoid receptor paulomycins Micromonospora antitumor Cantabrian Sea-derived actinobacteria puupehenones sponges antiangiogenic antitumoral porifera/sponge cancer genes molecular oncology bromophenol molecular mechanisms cell cycle PI3K/Akt p38/ERK ROS human lung cancer glycosaminoglycans antiproliferative heparan sulphate gliotoxin NSCLC adriamycin resistance Sepia ink polysaccharides antitumour chemosensitization anticoagulation sea anemone drug discovery endothelial cells RGD motif kunitz type inhibitor prostate cancer antioxidant natural marine compounds marine biotechnology microalgae marine sponges Aeroplysinin Isofistularin pheochromocytoma and paraganglioma metastasis cancer progression cell adhesion molecules integrin β1 hypoxia phycocyanin non-small cell lung cancer NF-κB signaling marine-derived drugs bioanalysis chromatography manzamine A epithelial-mesenchymal transition lung cancer circulating tumor cells signal transduction cisplatin Lampetra morii buccal gland cystatin F anti-angiogenesis cystatin superfamily Antimicrobial peptide (AMP) Tilapia piscidin 4 (TP4) non-small cell lung cancer (NSCLC) itampolin A FBDD p38α novel inhibitor tetracenomycin X cyclin D1 proteasomal degradation p38 c-JUN λ-carrageenan heparanase anticoagulant depolymerisation cell migration Aspergillus naphthopyrones endophytic fungus Leathesia nana mangrove-derived actinomycete ansamycins divergolides apoptosis-inducing activity actinomycin EMT invasion low molecular weight fucoidan extract N-Ras neuroblastoma-rat sarcoma Cancer programmed cell death-ligand 1 programmed cell death-ligand 2 human sarcoma cell line (HT1080 cells) human normal diploid fibroblast (TIG-1 cells) chimera chemical conjugation anticancer agent hybridization α9-nicotinic acetylcholine receptors (nAChRs) breast cancer cells αO-conotoxin GeXIVA targeted therapy gorgonian Leptogorgia humulane sesquiterpenoids anticancer activity 12-deacetyl-12-epi-scalaradial HeLa cells Nur77 MAPK/ERK pathway Mycalin A C15 acetogenins synthetic analogues antiproliferative activity A375 and HeLa cell lines polyoxygenated steroids sponge Haliclona gracilis Thalassia testudinum thalassiolin B polyphenols CYP1A1 benzo[a]pyrene JNK1/2 natural products synergism A549 cells cytoskeleton P2X7 receptor pollution anti-angiogenic gene expression HSP90 inhibitor |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557339303321 |
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Honecker Friedemann
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Matrix Metalloproteinase
| Matrix Metalloproteinase |
| Autore | Ågren Magnus S |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 |
| Descrizione fisica | 1 electronic resource (262 p.) |
| Soggetto topico |
Research & information: general
Biology, life sciences |
| Soggetto non controllato |
hemagglutinin-B
transwell co-cultures matrix metalloproteinases TNF-α matrix metalloproteinase peritoneal mesothelial cell gastric cancer metastatic dissemination MT4-MMP cancer diseases aggrecan aggrecanase ADAMTS cartilage arthritis MMP-2 MMP-9 inhibitor allodynia caspase-3 neuropathic pain dorsal root ganglion spinal nerve ligation tuberculosis tuberculous meningitis HIV-TB-associated IRIS extracellular matrix breakdown adult pediatric lung central nervous system matrix-metalloproteinase monocytes inflammation phagocytosis apoptosis blood sampling anticoagulants high-molecular-weight heparin IL-16 sICAM-1 IL-8 T cells a disintegrin and metalloproteinase EMMPRIN CD147 ectodomain shedding MMPs PTMs glycosylation phosphorylation glycosaminoglycans interleukin IL-6 IL-11 trans-signaling metalloproteases ADAM MMP meprin matrix metalloproteinases (MMPs) protease signaling invasion chemokine cytokine proteomics interferon Agkistrodon venom metalloproteinase fibrinogen antithrombotic metabolomics extracellular matrix cytokines proteinases interstitial collagens wound healing |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557717203321 |
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Ågren Magnus S
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Natural and Synthetic Bioactives for Skin Health, Disease and Management
| Natural and Synthetic Bioactives for Skin Health, Disease and Management |
| Autore | Chamcheu Jean Christopher |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 electronic resource (314 p.) |
| Soggetto topico |
Research & information: general
Biology, life sciences |
| Soggetto non controllato |
keratinocytes
rutin ascorbic acid UV radiation proteomics 3D cell culture borage oil triacylglycerol metabolism acyl-ceramide corneocyte lipid envelope epidermis anti-melanogenesis B16/F10 melanoma cell hydroxyoctadecadienoic acid Sorghum bicolor 3-isobutyl-1-methylxanthine mycosis fungoides atopic dermatitis cutaneous lymphomas cornified envelope proteins FLG microalgae Planktochlorella nurekis skin cells proliferation senescence holothuroids glycosaminoglycans inflammation ear-inflammation whey Lactobacillus helveticus melanin α-melanocyte-stimulating hormone tyrosinase tyrosinase-related protein 1 dopachrome tautomerase microphthalmia-associated transcription factor cosmetics black cumin Nigella sativa Thymocid® skin aging glycation collagen collagenase elastase melanogenesis cosmeceutical konjac glucomannan ultraviolet B human epidermal primary melanocytes human embryonic fibroblasts anti-inflammatory activity antioxidant activity Cornus officinalis molecular docking human high-affinity IgE receptors α-MSH UVB irradiation lotus seedpod extract epigallocatechin propolis skin matrix metalloproteinase-1 UV phosphoinositide 3-kinase skin care skin health bioactive substances phytonutrients antioxidants nutraceuticals Perilla frutescens cell proliferation ultraviolet radiation DNA repair Lactobacillus plantarum CJLP55 acne vulgaris sebum hydration urine bacterial extracellular vesicles fungal infections nanohydrogel polysaccharide essential oils eggshell membrane keratinocyte differentiation TRPV skin thickness Lithospermum erythrorhizon NC/Nga Th1 Th2 Th17 Th22 immune balance skin barrier function |
| ISBN | 3-0365-6068-8 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910639996003321 |
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Chamcheu Jean Christopher
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Neonatal Nutrition for Inflammatory Disorders and Necrotizing Enterocolitis
| Neonatal Nutrition for Inflammatory Disorders and Necrotizing Enterocolitis |
| Autore | Good Misty |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 |
| Descrizione fisica | 1 electronic resource (232 p.) |
| Soggetto topico |
Research & information: general
Biology, life sciences Food & society |
| Soggetto non controllato |
donor breast milk
human milk milk analysis very low birth weight preterm growth preterm infant donor human milk formula feeding breastfeeding necrotizing enterocolitis breast milk prematurity immunity newborn inflammation colostrum administration premature neonates clinical outcomes intestinal resection short bowel syndrome intestinal adaptation microbiome parenteral nutrition hormones milk fat globule long chain polyunsaturated fatty acids premature infants neonatal intestine glycosaminoglycans intestinal inflammation bioactive donor milk gastroschisis intestinal atresia human milk fortifier patient empowerment neonatal nutrition communication product labeling NICU parent extracellular vesicle exosome immature intestine formula osmolality breastmilk late onset sepsis bloodstream infections enteric pathogens human milk banks NEC meta-analysis breast-feeding spontaneous intestinal perforation feeding nutrition |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557783303321 |
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Good Misty
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Recent Developments on Protein–Ligand Interactions : From Structure, Function to Applications
| Recent Developments on Protein–Ligand Interactions : From Structure, Function to Applications |
| Autore | de Brevern Alexandre G |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 electronic resource (282 p.) |
| Soggetto topico |
Research & information: general
Biology, life sciences Biochemistry |
| Soggetto non controllato |
pimaricin thioesterase
protein-substrate interaction macrocyclization molecular dynamics (MD) simulation pre-reaction state folate folate receptor peptide conjugation click reaction biolayer interferometry acetylcholinesterase resistance organophosphorus pesticides molecular modeling lepidopterous insects conserved patterns similarity 3D-patterns epigenetics protein-RNA interaction RRM domain inhibitor NMR fragment-based screening TDP-43 galectin-1 gulopyranosides fluorescence polarization benzamide selective phospholipase C gamma 1 SLP76 virtual screening pharmacophore mapping molecular docking molecular dynamics caspase inhibition protein-ligand binding free energy Monte Carlo sampling docking and scoring molecular conformational sampling procollagen C-proteinase enhancer-1 glycosaminoglycans computational analysis of protein-glycosaminoglycan interactions calcium ions fragment-based docking protein–ligand analysis drug discovery and design structure–activity relationships bioremediation High Energy Molecules HMX protein design nitroreductase flavoprotein substrate specificity pharmacophore secretoglobin odorant-binding protein chemical communication pheromone N-phenyl-1-naphthylamine in silico docking protein–ligand interactions 2D interaction maps ligand-binding assays protein-ligand complexes dataset clustering structural alignment refinement PD-1/PD-L1 immune checkpoint inhibitors biphenyl-conjugated bromotyrosine amino acid conjugation amino-X in silico simulation IC50 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti |
Recent Developments on Protein–Ligand Interactions
Recent Developments on ProteinâLigand Interactions |
| Record Nr. | UNINA-9910566462703321 |
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de Brevern Alexandre G
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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