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A Personalized Medicine Approach to the Diagnosis and Management of Autism Spectrum Disorder
| A Personalized Medicine Approach to the Diagnosis and Management of Autism Spectrum Disorder |
| Autore | Frye Richard E |
| Pubbl/distr/stampa | Basel, : MDPI Books, 2022 |
| Descrizione fisica | 1 electronic resource (416 p.) |
| Soggetto topico |
Medicine
Neurosciences |
| Soggetto non controllato |
fecal metabolites
ASD microbiome gastrointestinal symptoms Fisher Discriminant Analysis digital biomarkers wearables time series analysis autism social dyads socio-motor parameters network connectivity non-linear complex dynamics stochastic analysis autism spectrum disorders copy number variants females Array-Comparative Genomic Hybridization (Array-CGH) autism spectrum disorder Ehlers-Danlos syndrome hypermobility spectrum disorders autonomic disorder mast cell activation syndrome genetic testing chromosomal microarray analysis whole exome sequencing whole genome sequencing clinical utility polygenic risk scores Temple Grandin biomarker omics precision medicine proteomics transcriptomics epigenetics metabolomics patient stratification mitochondria oxidative stress prenatal environment immune dysfunction immunoglobulin G intravenous immunoglobulin energy metabolism fatty acid oxidation acyl-carnitines resveratrol integrative model concomitant condition disorder autism spectrum disorder (ASD) genomics personalized treatment strategy single nucleotide polymorphisms clinical decision support tool ADHD PANDAS OCD anxiety folate receptor alpha folates pregnancy brain development fetal development cobalamin glutathione methylation methylcobalamin redox metabolism locked-in network syndrome resting-state functional magnetic resonance imaging temporal lobe epilepsy amygdala brain COVID-19 children cytokines flavonoids inflammation luteolin mast cells microglia SARS-CoV-2 stress nutraceuticals survey vitamins minerals B12 folinic acid quality of life parents intervention systematic review medical claims logistic regression analysis retrospective analysis associated risk monoamine neurotransmitters neurotransmitter deficiency cerebral folate deficiency folate receptor alpha autoantibodies leucovorin α-amylase cortisol heart rate variability neuromodulation sleep anxiety transdermal electrical neuromodulation neurostimulation |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910595075503321 |
Frye Richard E
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| Basel, : MDPI Books, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Antioxidant Activity of Polyphenolic Plant Extracts
| Antioxidant Activity of Polyphenolic Plant Extracts |
| Autore | Stagos Dimitrios |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 electronic resource (388 p.) |
| Soggetto topico |
Research & information: general
Biology, life sciences |
| Soggetto non controllato |
green leafy vegetables
effect of cooking polyphenols antioxidant activity Averrhoa bilimbi Oxalidaceae DPPH xanthine oxidase LC-QTOF-MS/MS molecular docking tentative bioactive constituents Dialium indum exocarp seed antioxidant phenolic acids amino acids GC-MS analysis AGN FIR phenolic flavonoid antioxidant capacity antimicrobial activity polyphenol compounds bixin rosemary extracts method validation HPLC food matrices fruit vinegar phenolics organic acid Ladastacho characterisation properties HPLC/ESI-MS HS-SPME/GC-MS beneficial use antimicrobial hydroxytyrosol rosemary pomegranate fish volatile compounds Rosa canina Rosa sempervivens Pyrocantha coccinea antioxidants endothelial cells glutathione almond skins bioavailability waste by-products flavonoids oxidative stress human reactive oxygen species proinflammatory cytokines Alzheimer's disease cornelian cherry anthocyanins gastrointestinal digestion Opuntia ficus-indica cladode antibiofilm activity olive Olea europaea anthocyanin cyanidin 3-glucoside cyanidin 3-rutinoside oxygen radical absorbance capacity (ORAC) high performance liquid chromatography mass spectrometry (HPLC-MS) tea Camellia sinensis polyphenol catechin caffeine theaflavine insulin resistance diabetes olive oil phenols antidiabetic myrtle ultrasound-assisted extraction phenolic compounds liquid chromatography analysis mass spectrometry mulberry (Morus nigra Morus alba) simple sugars organic acids phenol compounds high performance liquid chromatography/diode array detector/mass spectrometry anthocyanins anti-inflammatory activity extraction central composite design optimization P. officinalis phytochemicals cytotoxicity α-amylase inhibition red-osier dogwood antioxidative effect H2O2 transepithelial resistance (TEER) Caco-2 cells Rubus idaeus L. HPLC-ESI-HR-qTOF-MS/MS antioxidant activities digestive enzymes inhibitors molecular docking analysis olive mill wastewater encapsulation maltodextrin whey protein gelatin spray drying diabetes mellitus Lamiaceae alpha-glucosidase alpha-amylase Salvia africana-lutea terpenoids cape floristic region |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557728403321 |
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Stagos Dimitrios
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Antioxidants in Foods
| Antioxidants in Foods |
| Autore | Seiquer Isabel |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 electronic resource (418 p.) |
| Soggetto topico |
Research & information: general
Biology, life sciences Food & society |
| Soggetto non controllato |
green tea extract
food processing tannase ultrasound antioxidant activity liver injury acclimatisation antioxidant defences chlorophyll fluorescence in vitro culture peroxidase stevia plants 7S basic globulins anti-inflammatory protein antioxidant protein cytokines glutathione iNOS nitric oxide oxidative stress sweet lupins group home-cooking extra virgin olive oil UPLC-ESI-QqQ-MS/MS healthy cooking Mediterranean diet phenolic compounds bioactive compounds functional pasta gluten-free pasta bioaccessibility bioavailability whole grain composite flour legumes food by-products avocados (Persea americana Mill.) low temperatures plastochromanol-8 tocotrienols tocopherols tocochromanols kombucha tea fermentation antioxidant flavonoids polyphenols ascorbic acid chlorophyll and carotenoid content biodiversity Capsicum annuum L. β-carotene statistical analysis rye bread microencapsulation phenolics in vitro relative bioaccessibility lipoxygenase cyclooxygenase acetylcholinesterase biological activity lycopene antioxidants cancer diabetes cardiovascular diseases skin disorders free radicals spectrophotometer limitations chemical reactions colorimetry anthraquinone free radical scavenging inflammatory cytokines apoptosis Rumex crispus skins seeds Vitis vinifera cyclic voltammetry anthocyanin metabolites cardioprotection hepatoprotection nephroprotection neuroprotection antioxidant peptides element of pork carcasses spectrometric analysis ascorbate ascorbate-glutathione cycle capsaicin catalase dihydrocapsaicin NADP-dehydrogenases superoxide dismutase red cabbage in vitro gastrointestinal digestion acid-resistant capsule UHPLC-Q-Orbitrap HRMS apples reducing and chelating capacity HPLC-DAD-MS/MS Dillenia indica heme oxygenase 1 (HO-1) nuclear factor erythroid 2-related factor 2 (Nrf2) RAW 264.7 cells apo-carotenals bone osteoclasts NFκB synergy |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557728503321 |
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Seiquer Isabel
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Approaches in Enhancing Antioxidant Defense in Plants
| Approaches in Enhancing Antioxidant Defense in Plants |
| Autore | Fujita Masayuki |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 electronic resource (370 p.) |
| Soggetto topico |
Research & information: general
Biology, life sciences |
| Soggetto non controllato |
melatonin
water stress drought waterlogging abiotic stress antioxidants stress signaling phytohormones antioxidant biomolecules climate change reactive oxygen species halophytes soil salinity signaling molecules molybdenum cadmium stress photosynthetic pigments oxidative damage quality characters fragrant rice brassinosteroids chromium heavy metals rice adaptability heat stress water homeostasis hormone stoma transpiration antioxidant defense systems gene ontology miRNA 3D structures methyl jasmonate photosystem Brassica napus salinity stress antioxidant enzymes osmolytes ROS metabolites antioxidant defence ascorbate glutathione microspore embryogenesis Hordeum vulgare ×Triticosecale Wittm nitric oxide iron-deficiency chlorosis alfalfa chilling legumes pollen stigma acclimatization stress Cr+6 bioremediation improved antioxidant activity plant growth promotion rhizobacteria superoxide dismutase potato AlphaFold salicylic acid Glycine max seed germination photosynthesis secondary metabolites salinity |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910576885003321 |
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Fujita Masayuki
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Biomarkers and Nutrients in Musculoskeletal Disorders
| Biomarkers and Nutrients in Musculoskeletal Disorders |
| Autore | Calvo-Lobo César |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 electronic resource (120 p.) |
| Soggetto topico |
Humanities
Social interaction |
| Soggetto non controllato |
COVID-19
acute sedentary lifestyle step reduction positive energy balance metabolic consequences insulin resistance metabolic syndrome sarcopenia bowel diseases diet osteoporosis bone density nutrients muscle unloading muscle reloading sirtuin-1 muscle progenitor cells activated satellite cells quiescent satellite cells muscle regeneration markers electromyography high-fat diet myofascial pain syndrome obesity spontaneous neurotransmission vitamin D deficiency l-cysteine glutathione myogenic markers dystrophy markers skeletal muscle spinal muscular atrophy metabolomics nutrition therapeutics biomarkers |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557608803321 |
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Calvo-Lobo César
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Cancer Metabolomics 2018
| Cancer Metabolomics 2018 |
| Autore | Pinto Joana |
| Pubbl/distr/stampa | MDPI - Multidisciplinary Digital Publishing Institute, 2019 |
| Descrizione fisica | 1 electronic resource (184 p.) |
| Soggetto non controllato |
cell transporters
pharmacodynamics cell growth in vitro study metabolomic signatures endometabolome lung cancer metabolomics chemometric methods bladder cancer mTOR metabolite profiling metabolic pathways hepatocellular carcinoma glutamate senescence MCF7 breath analysis bio actives biomarker gas chromatography–mass spectrometry (GC–MS) GC-MS lung omics nutraceuticals glutaminase metabolism acylcarnitines Erwinaze Kidrolase glutathione targeted metabolomics apoptosis SLC1A5 essential amino acids cancer progression ASCT2 HR MAS alanine analytical platforms volatile organic compound glutaminolysis isotope tracing analysis asparaginase vitamin E breast cancer prognosis early diagnosis tocotrienols NMR prostate cancer in vitro cancer MDA-MB-231 |
| ISBN | 3-03921-346-6 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910367563603321 |
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Pinto Joana
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| MDPI - Multidisciplinary Digital Publishing Institute, 2019 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Centenarians-A Model to Study the Molecular Basis of Lifespan and Healthspan
| Centenarians-A Model to Study the Molecular Basis of Lifespan and Healthspan |
| Autore | Puca Annibale |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 electronic resource (204 p.) |
| Soggetto topico |
Research & information: general
Biology, life sciences |
| Soggetto non controllato |
aging
alternative therapy composition of royal jelly dietary interventions healthspan lifespan longevity royal jelly IGF-1 oxidative stress ageing nematode immunosenescence probiotic bacteria pathogen protection food allergy elderly hypersensitivity gut allergy inflammation redoxomics glutathione meniere's disease neurodegenerative diseases healthy aging DNA methylation epigenetic clocks telomere length centenarians exosomes serum functional enrichment analysis ingenuity pathway analysis miRNA-mRNA networks aging-related disease Di (2-Ethylhexyl) pthalate Hericium erinaceus vitagenes apoptosis mitochondrial respiratory complexes C. elegans polyphenols olive oil Parkinson's disease β-Dystroglycan cellular senescence lamin B1 DNA-damage response defective mitosis |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557783503321 |
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Puca Annibale
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Coumarin and Its Derivatives
| Coumarin and Its Derivatives |
| Autore | Matos Maria João |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 electronic resource (406 p.) |
| Soggetto topico |
Research & information: general
Biology, life sciences |
| Soggetto non controllato |
coumarin
hydroxyl-modified coumarin photophysical thermal and structural characterization Glycyrrhiza uralensis glycyrol liquiritigenin cholinesterases human monoamine oxidases kinetics docking simulation chalcone neurodegenerative diseases adenosine receptors binding affinity docking 4-hydroxy-7-methoxycoumarin macrophage inflammation NF-κB MAPK calanolides pseudocalanolides calanolide A Calophyllum Calophyllaceae anti-HIV reverse transcriptase non-nucleoside reverse transcriptase inhibitors (NNRTIs) osthole umbelliferone esculin 4-hydroxycoumarin sorafenib apoptosis autophagy Yin Chen Hao constitutive androstane receptor scoparone coumarins quorum sensing QS inhibitors plant-derived molecules Chromobacterium violaceum immunoproteasome psoralen core non-peptidic electrophilic compounds warhead scan inflammatory bowel disease isocoumarin Crohn's disease ulcerative colitis glutathione oxidative stress complementary therapies intestinal inflammation benzopyrones five-membered aromatic heterocycles furan pyrrole thiophene selenophen dihydrocoumarin-fused dihydropyranones 3-aroylcoumarines benzyl 2,3-butadienoate 6'-(4-biphenyl)-β-iso-cinchonine biological applications drug discovery fluorescent probes warfarin acenocoumarol mechanical valve time in therapeutic range anticoagulation Ruta chalepensis Rutaceae chalepin chalepensin bioactivity biosynthesis coumarin3-carboxamides pyranocoumarins anticancer activity antibacterial activity free radical polymerization LED photocomposites direct laser write analytical methods model plant natural genetic variation natural products simple coumarins chalcocoumarin MAO-B molecular dynamics in silico studies dye-sensitized solar cells coumarin dyes thieno [3,2-b] thiophene charge transfer ethynylaryl esculetin antiplatelet activity impedance aggregometry COX polyphenols pyrazole imidazole thiazole oxazole triazole thiadiazole curcumin curcumin-coumarin hybrids neuroprotection monoamine oxidase inhibition cholinesterase inhibition scavenging activity Escherichia coli biotransformation ferulenol structural annotation in silico tools |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557577003321 |
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Matos Maria João
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Cyclodextrin Chemistry and Toxicology
| Cyclodextrin Chemistry and Toxicology |
| Autore | Isidori Marina |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 electronic resource (248 p.) |
| Soggetto topico |
Research & information: general
Biology, life sciences |
| Soggetto non controllato |
cyclodextrin
sulfamethazine zwitterion host-guest complex thermodynamics nanosponges β-cyclodextrin glutathione cancer multicellular spheroids inclusion complexes solubilization nanosponge nanocarriers pharmaceutical applications molecular recognition phenomena molecular dynamics simulations drug delivery drug concentration dyeing textile finishing textile wastewater cyclodextrins HPβCD budesonide inflammation ROS Akt HDAC cholesterol medical imaging contrast agents α-cyclodextrin γ-cyclodextrin MRI PET CT SPECT PAI Cinnamomum osmophloeum linalool microencapsulation cyclodextrin inclusion solution-phase solid state antiretroviral 3-hydroxyflavone (3HF) γ-cyclodextrin (γ-CD) excited-state proton transfer (ESPT) molecular dynamics (MD) density functional theory (DFT) cyclodextrin polymers synthesis separation science materials science biomedicine retinal explant cytotoxicity uptake risperidone inclusion complex randomly methylated β-cyclodextrin compatibility studies excipients solubility stability aggregation doxorubicin nanoparticles alveograph wheat dough bread staling |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910585942703321 |
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Isidori Marina
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Delivery of Molecules Using Nanoscale Systems for Cancer Treatment and/or Diagnosis
| Delivery of Molecules Using Nanoscale Systems for Cancer Treatment and/or Diagnosis |
| Autore | Franco Marina Santiago |
| Pubbl/distr/stampa | Basel, : MDPI Books, 2022 |
| Descrizione fisica | 1 electronic resource (302 p.) |
| Soggetto topico |
Medicine
Pharmacology |
| Soggetto non controllato |
nanostructured lipid carriers
doxorubicin mucositis cell internalization albumin BSA CPP gold nanorods gold nanoprisms arginine-rich peptide glutathione nanoparticles oxidative stress breast cancer gastric cancer nanoparticle fucoidan d-alpha-tocopherylpoly (ethylene glycol) succinate combination chemotherapy G-quadruplex nucleolin DNA nanocages intracellular localization cancer targeting molecular dynamics simulations mesoporous silica nanoparticles radiotherapy immunotherapy tumor microenvironment abscopal effect magnetofection in vivo magnetic nanoparticles iron oxide gene delivery gene vectors codelivery nanocarriers photodynamic therapy anticancer therapies combination therapy phthalocyanine uterine cervical neoplasms photochemotherapy in vitro in vivo nanocarrier polyplexes siRNA delivery glioblastoma therapy amphiphilic poly(α)glutamate P-selectin prodrug drug delivery targeted therapy chemotherapy prostate cancer prostate-specific membrane antigen targeted delivery encapsulation cabazitaxel nanocarriers nanosystems radiosensitizer hypoxia synergism cancer photothermal therapy combined antitumor effect oxygenation hydrogel hypoxic tumor |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910595074103321 |
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Franco Marina Santiago
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| Basel, : MDPI Books, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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