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AMP-Activated Protein Kinase Signalling
| AMP-Activated Protein Kinase Signalling |
| Autore | Neumann Dietbert |
| Pubbl/distr/stampa | MDPI - Multidisciplinary Digital Publishing Institute, 2019 |
| Descrizione fisica | 1 electronic resource (452 p.) |
| Soggetto non controllato |
HDACs
transcription epigenetics spermatozoa par complex A769662 MDCK skeletal muscle AID phosphorylation energy metabolism monocytes autophagy CML liver hindlimb suspension pregnancy preeclampsia gestational diabetes mellitus CaMKK2 assisted reproduction techniques nutrient-sensing signals sonic hedgehog protein acetylation glycogen storage disease AMPK adenosine monophosphate-activated protein kinase AICAR indirect calorimetry IL-1? MyHC I(?) HDAC4/5 endothelial cells infection hepatocyte p70S6K lipid metabolism host defense exercise kidney disease heat shock protein ?RIM mycobacteria activation loop developmental origins of health and disease (DOHaD) CREB TAK1 metabolic-inflammation phenylephrine AMP-activated protein kinase (AMPK) KATs 2-methoxyestradiol DNA methylation NLRP3 pump ?-linker steatosis AMPK kinase stress endothelial nitric-oxide synthase vasodilation adherent junctions epithelial cells glycogen Akt synaptic activation cellular energy sensing glucose uptake transporter co-expression atrophy nutrigenomics motility vasoconstriction fatty acid oxidation oxidative stress AS160 membrane histone modification sirtuin 1 (SIRT1) chromatin remodeling insulin signalling dietary fatty acids ULK CMML adaptive thermogenesis mTOR MDS mechanical unloading AML endothelial function medulloblastoma PKA adipose tissue NAD+ membranes nutrition ZO-1 TBC1D4 adipocyte soluble Adenylyl cyclase metabolism renin-angiotensin system energy utilization proteasome differentiation signaling peroxisome proliferator-activated receptor gamma coactivator 1-? (PGC1?) hypertrophy AMP-activated protein kinase metabolic disease LKB1 soleus muscle macrophages Immediate early genes CBS benign motor endplate remodeling ionomycin nectin-afadin tight junctions resveratrol protein kinase B regrowth mitochondria protein synthesis energy deficiency catechol-O-methyltransferase fiber-type microarrays carrier acetyl-CoA hypertension 3T3-L1 hypothalamus food intake |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910346858503321 |
Neumann Dietbert
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| MDPI - Multidisciplinary Digital Publishing Institute, 2019 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Antitumoral Properties of Natural Products
| Antitumoral Properties of Natural Products |
| Autore | Fabiani Roberto |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 |
| Descrizione fisica | 1 electronic resource (344 p.) |
| Soggetto topico |
Research & information: general
Biology, life sciences |
| Soggetto non controllato |
cytotoxic activity
NCI-60 cancer cell line pristimerin Salacia crassifolia Celastraceae Brazilian Cerrado biome Salacia elliptica Cheiloclinium cognatum Plenckia populnea Aspergillus fumigatus Cordyceps sinensis isochromanes chiral resolution ECD calculation cytotoxicity coronarin D JNK osteosarcoma Zeylenone gastric cancer invasion migration apoptosis anti-cancer agents anthraquinones glycosyltransferase Dendrobium officinale structure elucidation anti-tumor activity plantation mode AR Ganoderma tsugae lipogenesis prostate cancer SREBP-1 ursolic acid betulinic acid triterpenoids necrotic quercetin quercetagetin patuletin lichen secondary metabolites tumidulin stemness potential colorectal cancer cells oncogene transcriptional regulation neferine FAK/S6K1 autophagy human neuroblastoma cells natural yellow Monascus pigments water-soluble antioxidation MCF-7 cells phloretin cell proliferation inflammation glucose uptake Catalpa speciosa Taxus cuspidata Magnolia acuminata phenols antioxidants anticancer Colocasia esculenta food bioactive tarin stable nanocapsules entrapment efficiency no-toxicity preclinical tests antitumoral activity chemotherapeutic adjuvant grape leaves ASE TP Antioxidant activities Antiproliferative pro-apoptotic effects Gene expression Nutraceuticals Cucurbitacin B gefitinib-resistant NSCLC EGFR lysosomal degradation CIP2A zerumbone cancer NF-κB IL-6/JAK2/STAT3 Akt FOXO1 multiple myeloma quality control naringenin flavonoids traditional preparation cancer stem cells phytochemicals plant-derived foods fruit vegetable cell signaling Artemisia absinthium endoplasmic reticulum stress mitochondrial-dependent pathway melanoma bee venom melittin temozolomide AKT MAPK antrodin C mTOR metabolic stability capsazepine inflammatory diseases ROS TRPV1 PI3K/AKT/mTOR CLE-10 LC3 MDA-MB-231 lactoferrin hydrolysate copper manganese gastric cancer cells anti-cancer activity molecular mechanism natural product alkaloids cephalotaxine protein synthesis inhibition antiproliferation agents folk medicine DLD-1 cells doxorubicin chemotherapy drug resistance CrataBL glioblastoma mesenchymal stem cells microenvironment plant lectin protease inhibitor cryptolepine neocryptolepine isocryptolepine antiproliferative activity structure activity relationships Licochalcone A ATM-Chk2 13-ethylberberine mitochondrial ROS RT-R breast cancer cells diallyl disulfide PI3K/Akt/mTOR pathway Pulsatilla saponin D SB365 glioblastoma multiforme autophagic flux inhibition lysosomal membrane permeabilization mitochondrial membrane potential CLEFMA p38 proanthocyanins TNF-α lung adenocarcinoma natural compounds cervical cancer cell cycle arrest dicentrine metastasis glioma semi-synthetic derivative ingenol Euphorbia tirucalli protein kinase C seaweed porphyran carrageenan anti-cancer natural products |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557419703321 |
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Fabiani Roberto
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Antitumoral Properties of Natural Products : Volume 2
| Antitumoral Properties of Natural Products : Volume 2 |
| Autore | Fabiani Roberto |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 |
| Descrizione fisica | 1 electronic resource (300 p.) |
| Soggetto topico |
Research & information: general
Biology, life sciences |
| Soggetto non controllato |
cytotoxic activity
NCI-60 cancer cell line pristimerin Salacia crassifolia Celastraceae Brazilian Cerrado biome Salacia elliptica Cheiloclinium cognatum Plenckia populnea Aspergillus fumigatus Cordyceps sinensis isochromanes chiral resolution ECD calculation cytotoxicity coronarin D JNK osteosarcoma Zeylenone gastric cancer invasion migration apoptosis anti-cancer agents anthraquinones glycosyltransferase Dendrobium officinale structure elucidation anti-tumor activity plantation mode AR Ganoderma tsugae lipogenesis prostate cancer SREBP-1 ursolic acid betulinic acid triterpenoids necrotic quercetin quercetagetin patuletin lichen secondary metabolites tumidulin stemness potential colorectal cancer cells oncogene transcriptional regulation neferine FAK/S6K1 autophagy human neuroblastoma cells natural yellow Monascus pigments water-soluble antioxidation MCF-7 cells phloretin cell proliferation inflammation glucose uptake Catalpa speciosa Taxus cuspidata Magnolia acuminata phenols antioxidants anticancer Colocasia esculenta food bioactive tarin stable nanocapsules entrapment efficiency no-toxicity preclinical tests antitumoral activity chemotherapeutic adjuvant grape leaves ASE TP Antioxidant activities Antiproliferative pro-apoptotic effects Gene expression Nutraceuticals Cucurbitacin B gefitinib-resistant NSCLC EGFR lysosomal degradation CIP2A zerumbone cancer NF-κB IL-6/JAK2/STAT3 Akt FOXO1 multiple myeloma quality control naringenin flavonoids traditional preparation cancer stem cells phytochemicals plant-derived foods fruit vegetable cell signaling Artemisia absinthium endoplasmic reticulum stress mitochondrial-dependent pathway melanoma bee venom melittin temozolomide AKT MAPK antrodin C mTOR metabolic stability capsazepine inflammatory diseases ROS TRPV1 PI3K/AKT/mTOR CLE-10 LC3 MDA-MB-231 lactoferrin hydrolysate copper manganese gastric cancer cells anti-cancer activity molecular mechanism natural product alkaloids cephalotaxine protein synthesis inhibition antiproliferation agents folk medicine DLD-1 cells doxorubicin chemotherapy drug resistance CrataBL glioblastoma mesenchymal stem cells microenvironment plant lectin protease inhibitor cryptolepine neocryptolepine isocryptolepine antiproliferative activity structure activity relationships Licochalcone A ATM-Chk2 13-ethylberberine mitochondrial ROS RT-R breast cancer cells diallyl disulfide PI3K/Akt/mTOR pathway Pulsatilla saponin D SB365 glioblastoma multiforme autophagic flux inhibition lysosomal membrane permeabilization mitochondrial membrane potential CLEFMA p38 proanthocyanins TNF-α lung adenocarcinoma natural compounds cervical cancer cell cycle arrest dicentrine metastasis glioma semi-synthetic derivative ingenol Euphorbia tirucalli protein kinase C seaweed porphyran carrageenan anti-cancer natural products |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | Antitumoral Properties of Natural Products |
| Record Nr. | UNINA-9910557531303321 |
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Fabiani Roberto
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Echinoderms Metabolites: Structure, Functions and Biomedical Perspectives
| Echinoderms Metabolites: Structure, Functions and Biomedical Perspectives |
| Autore | Kalinin Vladimir I |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 electronic resource (179 p.) |
| Soggetto topico | Medicine |
| Soggetto non controllato |
prostate cancer
thioglucoside conjugates natural products sea urchins glucose uptake polyhydroxysteroidal esters NMR spectra fatty acids starfish Ceramaster patagonicus cytostatic activity soft agar assay wound healing assay Colochirus quadrangularis triterpene glycosides quadrangularisosides sea cucumber cytotoxic activity Holothuria hilla Paracaudina chilensis fucosylated chondroitin sulfate anticoagulant activity echinochrome A echinamine A echinamine B herpes simplex virus type 1 Vero cells glycoprotein gD molecular docking Thyonidium kurilensis kurilosides Thenea muricata Aplysina sp Pseudoanthomastus agaricus Montastraea cavernosa Buccinum sp Pasiphaea tarda Phormosoma placenta Echinometra lucunter sterols gas chromatography mass spectrometry neuroblastoma Neuro-2a cells 5,8-dihydroxy-1,4-naphthoquinone O-glucoside thiomethylglycoside QSAR |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | Echinoderms Metabolites |
| Record Nr. | UNINA-9910557386103321 |
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Kalinin Vladimir I
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Ion and Molecule Transport in Membrane Systems
| Ion and Molecule Transport in Membrane Systems |
| Autore | Nikonenko Victor V |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 electronic resource (368 p.) |
| Soggetto topico | Technology: general issues |
| Soggetto non controllato |
ion exchange membranes
profiled membranes corrugated membranes electrodialysis reverse electrodialysis membrane capacitive deionization hydrodynamic mass transfer thermal pressing 3D printing acid whey pulsed electric field demineralization scaling lactic acid removal ion exchange membrane profiled membrane CFD pressure drop structural mechanics fluid-structure interaction whey pulsed electrodialysis reversal fouling electrodialysis with filtration membrane (EDFM) triple size-selective separation glucose uptake bioassay-guided validation bioactive peptides electro-convective instability overlimiting current concentration polarisation particle tracking biomimetic membrane ion pair amphiphile cholesterol molecular dynamics water permeation air-pollutant nanoparticle coarse-grained model interaction molecular dynamics simulation pulmonary surfactant monolayer PP membrane O2 plasma TiO2 nanoparticles UV treatment hydrophilicity biopolymer electrolyte membranes XRD analysis FTIR study Morphology Impedance study EDLC fabrication LaPO4: Ce Tb ionic liquid supported liquid membrane photoluminescence hyperbranched polymer crosslinking alkaline fuel cells ionic conductivity water swelling ion-exchange membranes ion-exchange particles heterogeneity electrokinetics current-voltage curves ion-exchange membrane Fujifilm Neosepta phosphate transport limiting current density voltammetry zinc-air battery separator hydroxide exchange membrane anion-exchange membrane ionic channel polyphenylene oxide polymer inclusion membrane ionic liquids volatile fatty acids (VFAs) acetic acids hexanoic acids anomalous water diffusion computer simulations ion channel gating nano-size water pore physico-chemical properties of confined water protein-water interactions TRPV1 channel permeability for water water dynamics water H-bonding NETs inner nuclear membrane outer nuclear membrane nuclear envelope polymer blends impedance study dielectric properties electric modulus study loss tangent peaks ion transport parameters Trukhan model salinity gradient power concentration difference electrolyte composition |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557579903321 |
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Nikonenko Victor V
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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