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mTOR in Human Diseases / Olivier Dormond
| mTOR in Human Diseases / Olivier Dormond |
| Autore | Dormond Olivier |
| Pubbl/distr/stampa | MDPI - Multidisciplinary Digital Publishing Institute, 2019 |
| Descrizione fisica | 1 electronic resource (480 p.) |
| Soggetto topico | Medicine |
| Soggetto non controllato |
primary cilia
neurodegeneration nutrient sensor PI3K transcriptomics phosphorylation metabolic reprogramming autophagy Alzheimer's disease rapalogs liver angiogenesis mTOR complex MBSCs advanced biliary tract cancers Medulloblastoma epithelial to mesenchymal transition AMPK p70S6K lipid metabolism thyroid cancer sodium iodide symporter (NIS)/SLC5A5 male fertility anesthesia illumina mTOR inhibitor miRNA Hutchinson-Gilford progeria syndrome (HGPS) eIFs Emery-Dreifuss muscular dystrophy (EDMD) glucose AKT oral cavity squamous cell carcinoma (OSCC) glucose and lipid metabolism cellular signaling aging tumor microenvironment rapamycin leukemia chloral hydrate rapalogues schizophrenia T-cell acute lymphoblastic leukemia senescence lamin A/C neurotoxicity neurodevelopment inhibitor methamphetamine pulmonary fibrosis mTOR mTOR inhibitors combination therapy proteolysis fluid shear stress tumour cachexia biomarkers synapse gluconeogenesis mTOR signal pathway Sertoli cells immunosenescence miRNome protein aggregation senolytics metabolism NGS mTORC2 mTORC1 metabolic diseases IonTorrent apoptosis dopamine receptor nocodazole microenvironment everolimus acute myeloid leukemia immunotherapy spermatogenesis bone remodeling signalling targeted therapy ageing therapy NVP-BEZ235 fructose physical activity laminopathies MC3T3-E1 cells cell signaling microRNA cancer lipolysis melatonin Parkinson's disease |
| ISBN |
9783039210619
3039210610 |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910346684303321 |
Dormond Olivier
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| MDPI - Multidisciplinary Digital Publishing Institute, 2019 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Plant Natural Products for Human Health
| Plant Natural Products for Human Health |
| Autore | Zhang Hongjie |
| Pubbl/distr/stampa | MDPI - Multidisciplinary Digital Publishing Institute, 2019 |
| Descrizione fisica | 1 online resource (514 p.) |
| Soggetto topico | Medicine |
| Soggetto non controllato |
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A549 cells acetaminophen acute liver injury AD adjuvant adjuvant-induced arthritis Amadori rearrangement compounds AMPK animals anti-inflammation anti-malaria activity antifungal activity antioxidant enzymes antiproliferation antistaphylococcal activity antitubercular activity APAP apoptosis arthritis aspirin Astragali Radix astragaloside IV automation bergamot bergapten biofilm bioinformatics biological activity bitter orange bleeding time BMP/Smad calorie restriction cannabigerol cannabinoid type 1 receptor Cannabis sativa caspases catechin celastrol cinnamamides computational softwares copaiba curcumin cytoxicity dendritic cells dietary supplements differentiation dihydromyricetin diterpenoids drug design and development drug discovery EGCG endoplasmic reticulum stress essential oil ethnopharmacology flavonoid flavonoids fucoidan garlic genistein ginseng global health glucans gluconeogenesis Glycyrrhiza uralensis gomisin N grapefruit green tea heart heat-process heme oxygenase HepaRG cells hepatic steatosis hepatotoxicity herb-drug interactions hinokitiol hpatoprotection human health human-hair-follicle dermal papilla cells hyperglycemia immune modulation immunomodulator inflammation inflammatory bowel disease innovation insulin resistance iridoids ischemia Keap1 kumquat lemon lime lipogenesis liposomes lychee seed mandarin medicinal plants melanoma cell microbiome migration mitochondrial bioenergetics mitogen-activated protein kinase MMPs molecular targets morin hydrate mouse-hair growth MTT assay myocardial hypertrophy NAFLD nanoparticles natural products neroli neuroinflammation Neuroprotective Nrf2 nuclear factor-kappaB OH· free radical oleoresin omics onion orange petitgrain oxidative stress oxygen consumption rate P. eryngii p53/Bax Panax notoginseng saponins paracetamol PC12 cells Penthorum chinense Pursh PET inhibition pharmacokinetic study PhGs phytocannabinoid phytochemicals plant natural product plants Plasmodium parasites platelet activation precision medicine preclinical studies prenylated flavonoids procyanidin A2 protein kinase reperfusion resveratrol rheumatoid arthritis scoulerine sesquiterpenoids Shh/Gli SIRT1 sirtuin 3 small molecules structure-activity relationship sweet orange targeted delivery TGF-? thromboembolism time-kill assay toxicity traditional medicine Tripterygium wilfordii triptolide triterpenic acids WNT/?-catenin yuzu Ziziphus jujuba |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910346688103321 |
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Zhang Hongjie
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| MDPI - Multidisciplinary Digital Publishing Institute, 2019 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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