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Intrinsically Disordered Proteins and Chronic Diseases
| Intrinsically Disordered Proteins and Chronic Diseases |
| Autore | Kulkarni Prakash |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 online resource (224 p.) |
| Soggetto topico | Research & information: general |
| Soggetto non controllato |
binding mechanism
coactivators conformational ensemble conformational plasticity COR15A depletion interaction diffusion disease-related proteins drug design dynamic configuration electrostatics entropic force extremely fuzzy complex free energy landscape functional segments fuzzy interactions gene regulation glucocorticoid receptor IDP intrinsic disordered protein intrinsically disordered intrinsically disordered protein intrinsically disordered proteins intrinsically disordered regions Kinase-inducible domain interacting domain kinetics Late embryogenesis abundant liquid-liquid phase separation low-complexity sequences membraneless organelles microtubule associated protein microtubules molecular dynamics molecular modelling mouse double minute 2 mouse double minute 4 n/a nuclear magnetic resonance Nuclear magnetic resonance optical tweezer order-disorder transition PAGE4 phosphomimetics phosphorylation protein complementation assays protein diffusion protein interaction protein structure prediction protein-protein interaction replica exchange molecular dynamics split-GFP reassembly subcellular location tau tau-microtubule association transactivation activity transient secondary structure Trifluoroethanol tumor protein p53 |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557746903321 |
Kulkarni Prakash
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Marine Compounds and Cancer 2020
| Marine Compounds and Cancer 2020 |
| Autore | Honecker Friedemann |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 online resource (480 p.) |
| Soggetto topico | Medicine and Nursing |
| Soggetto non controllato |
12-deacetyl-12-epi-scalaradial
3-alkylpyridinium polymers A375 and HeLa cell lines A549 cells ABC transporter actinomycin AD0157 adriamycin resistance Aeroplysinin Akt angiogenesis angiogenesis inhibitor ansamycins anthranilic acid anti-angiogenesis anti-angiogenic anti-cancer anti-metastatic activity anti-proliferation anti-proliferative antiangiogenesis antiangiogenic antibacterial Antibody Drug Conjugates (ADCs) anticancer anticancer activity anticancer agent anticancer immunity anticarcinogenic anticoagulant anticoagulation antifouling Antimicrobial peptide (AMP) antioxidant antiproliferative antiproliferative activity antitumor antitumor activities antitumoral antitumour AP-1 apoptosis apoptosis-inducing activity approved antitumor agents araguspongine C arrest of cell cycle Aspergillus autophagy autophagy inducers autophagy inhibitors azoxymethane BCRP/ABCG2 BEL-7402 cell benzo[a]pyrene bioactive natural product bioanalysis bis (2,3-dibromo-4,5-dihydroxy-phenyl)-methane (BDDPM) bonnethead shark breast cancer breast cancer cells Brevianamide brominated indoles bromophenol buccal gland c-JUN c-Met C15 acetogenins camptothecin cancer Cancer cancer genes cancer preventive cancer progression Cantabrian Sea-derived actinobacteria carbocyclic analogue carcinoembryonic antigen Caribbean sponge carotenoid carotenoids caspase cascade cell adhesion cell adhesion molecules cell cycle cell cycle arrest cell migration cembranoids chemical conjugation chemoprevention chemopreventive chemosensitization chemotherapy chimera CHOP chromatography circulating tumor cells cisplatin clinical trials colorectal cancer cooperative binding cyclin D1 cyclin-dependent kinase CYP1A1 cystatin F cystatin superfamily cytokine release cytoskeleton cytotoxic activity cytotoxicity deep-sea depolymerisation dibromotyrosine dieckol divergolides DNA minor groove binder drug discovery Ecklonia cava elisidepsin EMT endoperoxide endophytic fungus endothelial cells energy stress epigonal organ epithelial-mesenchymal transition ER-stress ET-743 evolution FAK fascaplysin fatty acid 2-hydroxylase fatty acids FAU FBDD fucoidan fucoxanthin fumigaclavine C gemcitabine gene expression glioblastoma gliotoxin glucocorticoid receptor glycosaminoglycans gorgonian Haliclona gracilis HeLa cells heparan sulphate heparanase hepatocellular carcinoma HER2 HIF-1 hippuristanol HSP90 human lung cancer human normal diploid fibroblast (TIG-1 cells) human sarcoma cell line (HT1080 cells) humulane sesquiterpenoids hybridization hydroxylated lipids hypoxia hypoxia-inducible factor-1 IL-6 in vivo model inflammation inhibitor integrin β1 invasion isatin Isofistularin itampolin A jaspine B JNK1/2 Jurkat kalkitoxin kunitz type inhibitor Lampetra morii Leathesia nana Leptogorgia leukemia lipid rafts low molecular weight fucoidan extract low toxic LS-1 lung cancer lung metastasis Lyngbya majuscula macrolide mangrove-derived actinomycete manzamine A MAPK/ERK pathway marangucyclines marine antitumor agents marine biotechnology marine compound marine drug marine drugs marine fungus marine metabolites marine mollusc marine natural products marine organisms marine sponges marine-derived drugs Marthasterias glacialis L. MCP-1 mechanisms of action melanoma membrane permeabilization metastasis microalgae Micromonospora migration mitochondria mitochondria toxin mitochondrial pathway mitochondrial dysfunction molecular docking molecular mechanisms molecular modeling molecular oncology Moorea producens MRP1/ABCC1 multi-drug resistant leukemia multidrug resistance Mycalin A Mycochromenic acid derivative N-Ras n/a nanoparticle naphthopyrones natural marine compounds natural product natural products neuroblastoma-rat sarcoma NF-κB NF-κB signaling nicotine nicotinic acetylcholine receptor non-small cell lung cancer non-small cell lung cancer (NSCLC) non-small cell lung carcinoma nonfunctioning pituitary adenomas novel inhibitor NSCLC Nur77 osteosarcoma oxidative stress oxidative stress P-gp/ABCB1 P2X7 receptor p38 p38/ERK p38α p65 pachastrissamine palmitic acid paulomycins pazopanib PEL Penicillium brevicompactum Penicillium paneum phase I pheochromocytoma and paraganglioma phlorotannins phycocyanin PI3K/Akt plakortide plitidepsin pollution poly(ADP-ribose)-polymerase inhibitor polyoxygenated steroids polyphenols polysaccharides Porifera porifera/sponge preclinical programmed cell death programmed cell death-ligand 1 programmed cell death-ligand 2 proliferation prostate cancer proteasomal degradation proteomic pseudopterosin puupehenones pyrrolidinedione reactive oxygen species RGD motif ribosomal protein genes ROS RPS30 safety Sarcophyton ehrenbergi sea anemone sea cucumbers seaweed secondary metabolites sediment selenium-containing polysaccharide-protein complex Sepia ink polysaccharides shrimp signal transduction sinulariolide sipholenol A small cell lung cancer SNORA62 snoRNA SNU-C5/5-FU soft coral soft tissue sarcoma soft tissue sarcoma sphingosine kinase inhibitor sponge sponges STAT3 Streptomyces sp. SCSIO 11594 synergism synthetic analogues SZ-685C targeted therapy terpenes tetracenomycin X TGF-β signaling Thalassia testudinum thalassiolin B therapeutic compounds Tilapia piscidin 4 (TP4) TNFα Topo I inhibitor topoisomerase trabectedin triterpene glycosides TRPM7 tumor cell line tumor microenvironment tumor-associated macrophages Ulva fasciata uveal melanoma VEGF virtual screening xyloketal B α9-nicotinic acetylcholine receptors (nAChRs) αO-conotoxin GeXIVA β1-integrin λ-carrageenan |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557339303321 |
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Honecker Friedemann
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Protective and Detrimental Role of Heme Oxygenase-1
| Protective and Detrimental Role of Heme Oxygenase-1 |
| Autore | Sorrenti Valeria |
| Pubbl/distr/stampa | MDPI - Multidisciplinary Digital Publishing Institute, 2019 |
| Descrizione fisica | 1 online resource (220 p.) |
| Soggetto topico | Medicine and Nursing |
| Soggetto non controllato |
adipocytes
analgesia angiotensin II antigen presentation ANTIGEN presenting cell apoptosis atherosclerosis Betula etnensis Raf bilirubin Caffeic acid phenethyl ester (CAPE) caloric restriction carbon monoxide cardiomyopathy carotid plaque chemotherapy Colon cancer coronary artery disease diabetes mellitus Dimethylarginine dimethylaminohydrolase-1 (DDAH-1) endoplasmic reticulum stress ER stress ferroptosis Gamma-Glutamyl-Cysteine Ligase (GGCL) glucocorticoid receptor glutathione GR Gunn rats heme heme oxigenase-1 heme oxygenase heme oxygenase 1 heme oxygenase-1 Heme Oxygenase-1 Heme oxygenase-1 (HO-1) inducers hemoglobin high-pressure gas HO-1 HO-1 activity inhibitor hyperbilirubinemia Inducible nitric oxide synthase (iNOS) inflammation inflammatory pain iron ischemia-reperfusion injury liver locus coeruleus LPS lung preservation metformin mineralocorticoid receptor Myristica fragrans kernels n/a NF-?B nitric oxide oxidative stress Pancreatic oxidative damage paracetamol peripheral artery disease PGC-1? prostate cancer reactive oxygen species Reactive oxygen species (ROS) sirtuin 1 Sirtuin 1 Tet-ON system thiol groups tolerance Type 1 diabetes mellitus (T1D) |
| ISBN | 3-03921-807-7 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910367746303321 |
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Sorrenti Valeria
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| MDPI - Multidisciplinary Digital Publishing Institute, 2019 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Stress and Health : Understanding the Effects and Examining Interventions
| Stress and Health : Understanding the Effects and Examining Interventions |
| Autore | Taylor Alyx |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 online resource (108 p.) |
| Soggetto topico |
Humanities
Social interaction |
| Soggetto non controllato |
acculturative stress
adverse childhood experiences attachment child abuse commercial smartwatch cortisol electrodermal activity emotion regulation FKBP5 glucocorticoid receptor glucocorticoids heart rate variability immigrants mental stress North Korean refugees NR3C1 parenting self-efficacy posttraumatic stress disorder psychophysiological psychosocial well-being psychotherapy qualitative case study social inclusion trauma and stressor related disorders war veterans youth health youth mentoring |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | Stress and Health |
| Record Nr. | UNINA-9910557641303321 |
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Taylor Alyx
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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The Era of Assisted Reproductive Technologies Tailored to the Specific Necessities of Species, Industry and Case Reports
| The Era of Assisted Reproductive Technologies Tailored to the Specific Necessities of Species, Industry and Case Reports |
| Autore | Martín Hidalgo David |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 online resource (258 p.) |
| Soggetto topico | Medicine |
| Soggetto non controllato |
ARTs
assisted reproductive technologies assisted reproductive technology biobanking BMP15 boar spermatozoa calving capacitation chemotaxis cryopreservation cryopreserved sperm embryo embryo development embryo transfer embryo vitrification equine equines exosomes extender extracellular vesicles female genital tract fertilizing ability gene expression glucocorticoid receptor Gompertz growth curve horse in vitro embryo production in vitro fertilization in vitro production IVC IVF IVM liposomes livestock production metabolomic micromanipulation nanoparticles oocyte oocyte competence oocytes ovary storage penicillamine perfluorinated compounds PFHxS PFOS porcine pregnancy rabbit ram red light irradiation reproductive fluids reproductive performance RT-qPCR selection selection programme semen semen extender semen freezing semen quality seminal plasma sheep sperm sperm selection sperm-oviduct interaction spermatozoa spermatozoa toxicology stallion sperm stallions straw thermotaxis transport Tris vitrification |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557717303321 |
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Martín Hidalgo David
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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