Info
- Utilizzare la checkbox di selezione a fianco di ciascun documento per attivare le funzionalità di stampa, invio email, download nei formati disponibili del (i) record.
Intrinsically Disordered Proteins and Chronic Diseases
| Intrinsically Disordered Proteins and Chronic Diseases |
| Autore | Kulkarni Prakash |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 electronic resource (224 p.) |
| Soggetto topico | Research & information: general |
| Soggetto non controllato |
IDP
fuzzy interactions protein complementation assays split-GFP reassembly kinetics membraneless organelles optical tweezer liquid-liquid phase separation protein diffusion depletion interaction entropic force low-complexity sequences intrinsically disordered proteins PAGE4 conformational plasticity order-disorder transition phosphorylation intrinsic disordered protein extremely fuzzy complex protein interaction binding mechanism tumor protein p53 mouse double minute 2 mouse double minute 4 Kinase-inducible domain interacting domain phosphomimetics nuclear magnetic resonance transient secondary structure COR15A Late embryogenesis abundant Trifluoroethanol Nuclear magnetic resonance intrinsically disordered regions functional segments disease-related proteins protein-protein interaction subcellular location glucocorticoid receptor intrinsically disordered transactivation activity gene regulation coactivators microtubule associated protein tau intrinsically disordered protein dynamic configuration free energy landscape microtubules electrostatics diffusion protein structure prediction molecular modelling molecular dynamics tau-microtubule association conformational ensemble replica exchange molecular dynamics drug design |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557746903321 |
Kulkarni Prakash
|
||
| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Marine Compounds and Cancer 2020
| Marine Compounds and Cancer 2020 |
| Autore | Honecker Friedemann |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 electronic resource (480 p.) |
| Soggetto topico | Medicine |
| Soggetto non controllato |
apoptosis
fucoidan hepatocellular carcinoma reactive oxygen species 3-alkylpyridinium polymers nicotine nicotinic acetylcholine receptor non-small cell lung carcinoma melanoma sinulariolide proteomic mitochondria caspase cascade marine fungus sediment anthranilic acid Penicillium paneum cytotoxicity dibromotyrosine mitochondrial dysfunction oxidative stress topoisomerase epigonal organ bonnethead shark Jurkat tumor cell line hippuristanol PEL AP-1 STAT3 Akt colorectal cancer marine mollusc brominated indoles shrimp chemoprevention fatty acids carotenoids cancer nanoparticle osteosarcoma lung metastasis elisidepsin lipid rafts hydroxylated lipids fatty acid 2-hydroxylase cooperative binding membrane permeabilization marine organisms polysaccharides anticancer anticarcinogenic mechanisms of action fumigaclavine C anti-proliferation mitochondrial pathway anti-cancer anti-proliferative carotenoid cell cycle arrest fucoxanthin azoxymethane bioactive natural product isatin in vivo model Marthasterias glacialis L. palmitic acid ER-stress CHOP Antibody Drug Conjugates (ADCs) marine antitumor agents clinical trials approved antitumor agents AD0157 angiogenesis marine drug pyrrolidinedione secondary metabolites cancer preventive chemopreventive trabectedin plitidepsin tumor-associated macrophages tumor microenvironment preclinical anticancer immunity antiangiogenesis fascaplysin cyclin-dependent kinase small cell lung cancer camptothecin poly(ADP-ribose)-polymerase inhibitor breast cancer seaweed therapeutic compounds autophagy marine drugs autophagy inhibitors autophagy inducers macrolide programmed cell death energy stress araguspongine C c-Met HER2 gemcitabine pazopanib phase I safety soft tissue sarcoma pachastrissamine jaspine B carbocyclic analogue sphingosine kinase inhibitor molecular modeling ET-743 DNA minor groove binder soft tissue sarcoma chemotherapy bis (2,3-dibromo-4,5-dihydroxy-phenyl)-methane (BDDPM) anti-metastatic activity cell adhesion β1-integrin FAK BEL-7402 cell triterpene glycosides sea cucumbers antitumor activities arrest of cell cycle antibacterial marangucyclines deep-sea Streptomyces sp. SCSIO 11594 LS-1 SNU-C5/5-FU TGF-β signaling carcinoembryonic antigen kalkitoxin Moorea producens mitochondria toxin VEGF angiogenesis inhibitor hypoxia-inducible factor-1 HIF-1 Lyngbya majuscula marine metabolites SZ-685C nonfunctioning pituitary adenomas Ecklonia cava phlorotannins dieckol migration sipholenol A ABC transporter multidrug resistance P-gp/ABCB1 BCRP/ABCG2 MRP1/ABCC1 marine natural products glioblastoma xyloketal B proliferation TRPM7 marine compound ribosomal protein genes snoRNA FAU RPS30 SNORA62 evolution Porifera Penicillium brevicompactum Brevianamide Mycochromenic acid derivative antifouling Caribbean sponge plakortide endoperoxide leukemia multi-drug resistant leukemia Sarcophyton ehrenbergi soft coral terpenes cembranoids cytotoxic activity molecular docking uveal melanoma oxidative stress virtual screening Topo I inhibitor low toxic natural product Ulva fasciata selenium-containing polysaccharide-protein complex pseudopterosin NF-κB p65 inflammation cytokine release IL-6 TNFα MCP-1 glucocorticoid receptor paulomycins Micromonospora antitumor Cantabrian Sea-derived actinobacteria puupehenones sponges antiangiogenic antitumoral porifera/sponge cancer genes molecular oncology bromophenol molecular mechanisms cell cycle PI3K/Akt p38/ERK ROS human lung cancer glycosaminoglycans antiproliferative heparan sulphate gliotoxin NSCLC adriamycin resistance Sepia ink polysaccharides antitumour chemosensitization anticoagulation sea anemone drug discovery endothelial cells RGD motif kunitz type inhibitor prostate cancer antioxidant natural marine compounds marine biotechnology microalgae marine sponges Aeroplysinin Isofistularin pheochromocytoma and paraganglioma metastasis cancer progression cell adhesion molecules integrin β1 hypoxia phycocyanin non-small cell lung cancer NF-κB signaling marine-derived drugs bioanalysis chromatography manzamine A epithelial-mesenchymal transition lung cancer circulating tumor cells signal transduction cisplatin Lampetra morii buccal gland cystatin F anti-angiogenesis cystatin superfamily Antimicrobial peptide (AMP) Tilapia piscidin 4 (TP4) non-small cell lung cancer (NSCLC) itampolin A FBDD p38α novel inhibitor tetracenomycin X cyclin D1 proteasomal degradation p38 c-JUN λ-carrageenan heparanase anticoagulant depolymerisation cell migration Aspergillus naphthopyrones endophytic fungus Leathesia nana mangrove-derived actinomycete ansamycins divergolides apoptosis-inducing activity actinomycin EMT invasion low molecular weight fucoidan extract N-Ras neuroblastoma-rat sarcoma Cancer programmed cell death-ligand 1 programmed cell death-ligand 2 human sarcoma cell line (HT1080 cells) human normal diploid fibroblast (TIG-1 cells) chimera chemical conjugation anticancer agent hybridization α9-nicotinic acetylcholine receptors (nAChRs) breast cancer cells αO-conotoxin GeXIVA targeted therapy gorgonian Leptogorgia humulane sesquiterpenoids anticancer activity 12-deacetyl-12-epi-scalaradial HeLa cells Nur77 MAPK/ERK pathway Mycalin A C15 acetogenins synthetic analogues antiproliferative activity A375 and HeLa cell lines polyoxygenated steroids sponge Haliclona gracilis Thalassia testudinum thalassiolin B polyphenols CYP1A1 benzo[a]pyrene JNK1/2 natural products synergism A549 cells cytoskeleton P2X7 receptor pollution anti-angiogenic gene expression HSP90 inhibitor |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557339303321 |
|
Honecker Friedemann
|
||
| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Protective and Detrimental Role of Heme Oxygenase-1
| Protective and Detrimental Role of Heme Oxygenase-1 |
| Autore | Sorrenti Valeria |
| Pubbl/distr/stampa | MDPI - Multidisciplinary Digital Publishing Institute, 2019 |
| Descrizione fisica | 1 electronic resource (220 p.) |
| Soggetto non controllato |
coronary artery disease
glucocorticoid receptor antigen presentation analgesia chemotherapy locus coeruleus Sirtuin 1 thiol groups Heme Oxygenase-1 Betula etnensis Raf heme oxygenase 1 tolerance heme oxygenase atherosclerosis nitric oxide caloric restriction liver carbon monoxide ER stress heme oxygenase-1 mineralocorticoid receptor Type 1 diabetes mellitus (T1D) Gamma-Glutamyl-Cysteine Ligase (GGCL) angiotensin II bilirubin Heme oxygenase-1 (HO-1) inducers Inducible nitric oxide synthase (iNOS) HO-1 activity inhibitor ferroptosis Myristica fragrans kernels glutathione high-pressure gas apoptosis HO-1 diabetes mellitus Caffeic acid phenethyl ester (CAPE) carotid plaque ischemia-reperfusion injury ANTIGEN presenting cell LPS endoplasmic reticulum stress hemoglobin Pancreatic oxidative damage Colon cancer inflammation reactive oxygen species inflammatory pain paracetamol cardiomyopathy heme oxigenase-1 adipocytes sirtuin 1 peripheral artery disease PGC-1? heme Reactive oxygen species (ROS) metformin GR prostate cancer NF-?B hyperbilirubinemia iron Tet-ON system lung preservation oxidative stress Gunn rats Dimethylarginine dimethylaminohydrolase-1 (DDAH-1) |
| ISBN | 3-03921-807-7 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910367746303321 |
|
Sorrenti Valeria
|
||
| MDPI - Multidisciplinary Digital Publishing Institute, 2019 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Stress and Health : Understanding the Effects and Examining Interventions
| Stress and Health : Understanding the Effects and Examining Interventions |
| Autore | Taylor Alyx |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 electronic resource (108 p.) |
| Soggetto topico |
Stress, Psychological - physiopathology
Psychophysiologic Disorders - etiology Psychosocial Intervention Behavioral Research Humanities Social interaction |
| Soggetto non controllato |
commercial smartwatch
mental stress psychophysiological emotion regulation heart rate variability electrodermal activity posttraumatic stress disorder war veterans trauma and stressor related disorders adverse childhood experiences attachment psychotherapy glucocorticoids cortisol glucocorticoid receptor NR3C1 FKBP5 youth mentoring immigrants social inclusion psychosocial well-being youth health acculturative stress North Korean refugees child abuse parenting self-efficacy qualitative case study |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | Stress and Health |
| Record Nr. | UNINA-9910557641303321 |
|
Taylor Alyx
|
||
| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
The Era of Assisted Reproductive Technologies Tailored to the Specific Necessities of Species, Industry and Case Reports
| The Era of Assisted Reproductive Technologies Tailored to the Specific Necessities of Species, Industry and Case Reports |
| Autore | Martín Hidalgo David |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 electronic resource (258 p.) |
| Soggetto topico | Medicine |
| Soggetto non controllato |
IVM
oocytes equine metabolomic embryo transfer reproductive fluids pregnancy vitrification calving selection programme embryo vitrification Gompertz growth curve biobanking reproductive performance stallion sperm capacitation penicillamine thermotaxis selection BMP15 ram semen semen freezing semen extender stallions semen quality fertilizing ability Tris boar spermatozoa perfluorinated compounds PFHxS PFOS spermatozoa toxicology glucocorticoid receptor gene expression RT-qPCR seminal plasma female genital tract rabbit spermatozoa oocyte in vitro fertilization extracellular vesicles assisted reproductive technologies embryo oocyte competence livestock production assisted reproductive technology embryo development micromanipulation in vitro production nanoparticles liposomes exosomes cryopreservation sheep ovary storage transport in vitro embryo production sperm selection chemotaxis IVF IVC porcine cryopreserved sperm sperm–oviduct interaction ARTs equines horse sperm red light irradiation extender straw |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557717303321 |
|
Martín Hidalgo David
|
||
| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||