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Antitumoral Properties of Natural Products
| Antitumoral Properties of Natural Products |
| Autore | Fabiani Roberto |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 |
| Descrizione fisica | 1 electronic resource (344 p.) |
| Soggetto topico |
Research & information: general
Biology, life sciences |
| Soggetto non controllato |
cytotoxic activity
NCI-60 cancer cell line pristimerin Salacia crassifolia Celastraceae Brazilian Cerrado biome Salacia elliptica Cheiloclinium cognatum Plenckia populnea Aspergillus fumigatus Cordyceps sinensis isochromanes chiral resolution ECD calculation cytotoxicity coronarin D JNK osteosarcoma Zeylenone gastric cancer invasion migration apoptosis anti-cancer agents anthraquinones glycosyltransferase Dendrobium officinale structure elucidation anti-tumor activity plantation mode AR Ganoderma tsugae lipogenesis prostate cancer SREBP-1 ursolic acid betulinic acid triterpenoids necrotic quercetin quercetagetin patuletin lichen secondary metabolites tumidulin stemness potential colorectal cancer cells oncogene transcriptional regulation neferine FAK/S6K1 autophagy human neuroblastoma cells natural yellow Monascus pigments water-soluble antioxidation MCF-7 cells phloretin cell proliferation inflammation glucose uptake Catalpa speciosa Taxus cuspidata Magnolia acuminata phenols antioxidants anticancer Colocasia esculenta food bioactive tarin stable nanocapsules entrapment efficiency no-toxicity preclinical tests antitumoral activity chemotherapeutic adjuvant grape leaves ASE TP Antioxidant activities Antiproliferative pro-apoptotic effects Gene expression Nutraceuticals Cucurbitacin B gefitinib-resistant NSCLC EGFR lysosomal degradation CIP2A zerumbone cancer NF-κB IL-6/JAK2/STAT3 Akt FOXO1 multiple myeloma quality control naringenin flavonoids traditional preparation cancer stem cells phytochemicals plant-derived foods fruit vegetable cell signaling Artemisia absinthium endoplasmic reticulum stress mitochondrial-dependent pathway melanoma bee venom melittin temozolomide AKT MAPK antrodin C mTOR metabolic stability capsazepine inflammatory diseases ROS TRPV1 PI3K/AKT/mTOR CLE-10 LC3 MDA-MB-231 lactoferrin hydrolysate copper manganese gastric cancer cells anti-cancer activity molecular mechanism natural product alkaloids cephalotaxine protein synthesis inhibition antiproliferation agents folk medicine DLD-1 cells doxorubicin chemotherapy drug resistance CrataBL glioblastoma mesenchymal stem cells microenvironment plant lectin protease inhibitor cryptolepine neocryptolepine isocryptolepine antiproliferative activity structure activity relationships Licochalcone A ATM-Chk2 13-ethylberberine mitochondrial ROS RT-R breast cancer cells diallyl disulfide PI3K/Akt/mTOR pathway Pulsatilla saponin D SB365 glioblastoma multiforme autophagic flux inhibition lysosomal membrane permeabilization mitochondrial membrane potential CLEFMA p38 proanthocyanins TNF-α lung adenocarcinoma natural compounds cervical cancer cell cycle arrest dicentrine metastasis glioma semi-synthetic derivative ingenol Euphorbia tirucalli protein kinase C seaweed porphyran carrageenan anti-cancer natural products |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557419703321 |
Fabiani Roberto
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Antitumoral Properties of Natural Products : Volume 2
| Antitumoral Properties of Natural Products : Volume 2 |
| Autore | Fabiani Roberto |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 |
| Descrizione fisica | 1 electronic resource (300 p.) |
| Soggetto topico |
Research & information: general
Biology, life sciences |
| Soggetto non controllato |
cytotoxic activity
NCI-60 cancer cell line pristimerin Salacia crassifolia Celastraceae Brazilian Cerrado biome Salacia elliptica Cheiloclinium cognatum Plenckia populnea Aspergillus fumigatus Cordyceps sinensis isochromanes chiral resolution ECD calculation cytotoxicity coronarin D JNK osteosarcoma Zeylenone gastric cancer invasion migration apoptosis anti-cancer agents anthraquinones glycosyltransferase Dendrobium officinale structure elucidation anti-tumor activity plantation mode AR Ganoderma tsugae lipogenesis prostate cancer SREBP-1 ursolic acid betulinic acid triterpenoids necrotic quercetin quercetagetin patuletin lichen secondary metabolites tumidulin stemness potential colorectal cancer cells oncogene transcriptional regulation neferine FAK/S6K1 autophagy human neuroblastoma cells natural yellow Monascus pigments water-soluble antioxidation MCF-7 cells phloretin cell proliferation inflammation glucose uptake Catalpa speciosa Taxus cuspidata Magnolia acuminata phenols antioxidants anticancer Colocasia esculenta food bioactive tarin stable nanocapsules entrapment efficiency no-toxicity preclinical tests antitumoral activity chemotherapeutic adjuvant grape leaves ASE TP Antioxidant activities Antiproliferative pro-apoptotic effects Gene expression Nutraceuticals Cucurbitacin B gefitinib-resistant NSCLC EGFR lysosomal degradation CIP2A zerumbone cancer NF-κB IL-6/JAK2/STAT3 Akt FOXO1 multiple myeloma quality control naringenin flavonoids traditional preparation cancer stem cells phytochemicals plant-derived foods fruit vegetable cell signaling Artemisia absinthium endoplasmic reticulum stress mitochondrial-dependent pathway melanoma bee venom melittin temozolomide AKT MAPK antrodin C mTOR metabolic stability capsazepine inflammatory diseases ROS TRPV1 PI3K/AKT/mTOR CLE-10 LC3 MDA-MB-231 lactoferrin hydrolysate copper manganese gastric cancer cells anti-cancer activity molecular mechanism natural product alkaloids cephalotaxine protein synthesis inhibition antiproliferation agents folk medicine DLD-1 cells doxorubicin chemotherapy drug resistance CrataBL glioblastoma mesenchymal stem cells microenvironment plant lectin protease inhibitor cryptolepine neocryptolepine isocryptolepine antiproliferative activity structure activity relationships Licochalcone A ATM-Chk2 13-ethylberberine mitochondrial ROS RT-R breast cancer cells diallyl disulfide PI3K/Akt/mTOR pathway Pulsatilla saponin D SB365 glioblastoma multiforme autophagic flux inhibition lysosomal membrane permeabilization mitochondrial membrane potential CLEFMA p38 proanthocyanins TNF-α lung adenocarcinoma natural compounds cervical cancer cell cycle arrest dicentrine metastasis glioma semi-synthetic derivative ingenol Euphorbia tirucalli protein kinase C seaweed porphyran carrageenan anti-cancer natural products |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | Antitumoral Properties of Natural Products |
| Record Nr. | UNINA-9910557531303321 |
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Fabiani Roberto
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Biomarkers in Neurodegenerative Diseases
| Biomarkers in Neurodegenerative Diseases |
| Autore | Ghosh Arnab |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 electronic resource (190 p.) |
| Soggetto topico | Medicine |
| Soggetto non controllato |
Alzheimer's disease
amyloid beta hippocampus Kir channels K+ channels glioblastoma multiforme low-grade glioma astrocytoma recurrence multifocal growth mRNA expression MPS1 TTK therapy EDTA chelation therapy neurodegenerative diseases metal detoxification reactive oxygen species (ROS) neuroinflammation neurodegeneration cognitive dysfunction neurofibrillary tangles diagnosis methods biomarkers perinatal stress NURR1 inflammation late-onset diseases early life artificial neural network deep learning Parkinson's disease atypical parkinsonian syndrome dopamine transporter SPECT β-Amyloid calpain Collapsin Response Mediator Protein-2 human-neuroblastoma SH-SY5Y cells Somatostatin-14 somatostatin receptor brain injury quinpirole dopamine D2 receptors glial cell autophagy mitophagy multiple sclerosis biomarker neurons astrocytes Alzheimer's and Parkinson's diseases fluid and imaging biomarkers amyloid-β and tau miRNA extracellular vesicles exosomes and ectosomes PET radiotracers radiolabeled molecules |
| ISBN | 3-0365-5730-X |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910640000503321 |
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Ghosh Arnab
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Brain-Targeted Drug Delivery
| Brain-Targeted Drug Delivery |
| Autore | Sousa Flávia |
| Pubbl/distr/stampa | MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 electronic resource (260 p.) |
| Soggetto topico | Technology: general issues |
| Soggetto non controllato |
drug delivery into the brain
transendothelium based on receptor-mediated transcytosis immunotherapy Alzheimer's disease anti-tau and anti-receptor bispecific monoclonal antibodies Alzheimer's disease-relevant tau species temporal-spatial pathological Aβ and tau distribution interactions between Aβ and tau tau clearance in microglia tau clearance in neurons liposome nanoparticle seizure laser ultrasound naringenin nanostructured lipid carrier intranasal delivery central composite rotatable design depression pomegranate seed oil nasal delivery system memory impairment movement impairment delivery to brain improved memory phospholipid oily gel high-grade glioma diffuse midline glioma glioblastoma IL-13Rα2 IL-13 immunotoxin targeted therapy GB-13 IL13.E13K-PE4E receptor expression acetaminophen blood-brain barrier claudin-5 CNS drug delivery opioids tight junction microdialysis cerebral open flow microperfusion electrochemical biosensors macromolecules tolcapone microparticles nanoparticles PLGA Parkinson's disease nose to brain delivery gene therapy polyplexes hyaluronidase glycol chitosan brain cancer chemoattractant CXCL CXCR glioblastoma multiforme 3D cell culture systems non-human primate convection-enhanced delivery neurosurgery optogenetics brain targeted therapy drug delivery cerebrospinal fluid microcirculation brain biodistribution |
| ISBN | 3-0365-5281-2 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910619467203321 |
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Sousa Flávia
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| MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Curcumin in Health and Disease
| Curcumin in Health and Disease |
| Autore | Bachmeier Beatrice |
| Pubbl/distr/stampa | MDPI - Multidisciplinary Digital Publishing Institute, 2019 |
| Descrizione fisica | 1 electronic resource (274 p.) |
| Soggetto non controllato |
minerals
cancer treatment chitosan neurodegeneration antioxidant activity senescence tumor proliferation nanoparticles antimicrobial agents oxidative metabolites drug discovery Akt/mTOR signaling micronutrients ulcerative colitis transmission electron microscopy metabolic reprogramming curcumin death receptor chaperone-mediated autophagy wound healing brain ischemia autophagy Alzheimer's disease genes transthyretin inflammatory bowel disease cellular pathway centrifugal partition chromatography nutrition amyloid Curcuma longa protein aggregation supportive care IL-17 senolytics complementary medicine macronutrients structure activity relationship gastroprotection Zingiberaceae anti-inflamation TLC bioautography microbiota glioblastoma multiforme amyloidosis SHMT2 antioxidants silica apoptosis reflux esophagitis gastric ulcer TLC-MS anti-cancer anticancer ImageJ anti-tumor delivery system wound Helicobacter pylori direct protein binding protein misfolding tumor growth diet Crohn's disease hydrostatic counter-current chromatography ageing renal cell cancer gastric cancer amino-acids STAT3 mechanism of action inflamm-aging mitophagy necrotizing enterocolitis cell cycling vitamins turmeric tuber cancer tau protein |
| ISBN | 3-03921-450-0 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910367753703321 |
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Bachmeier Beatrice
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| MDPI - Multidisciplinary Digital Publishing Institute, 2019 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Diet in brain health and neurological disorders : risk factors and treatments / / special issue editor, Jason Brandt
| Diet in brain health and neurological disorders : risk factors and treatments / / special issue editor, Jason Brandt |
| Pubbl/distr/stampa | MDPI - Multidisciplinary Digital Publishing Institute, 2019 |
| Descrizione fisica | 1 electronic resource (68 p.) |
| Disciplina | 616.8/04654 |
| Soggetto topico | Brain - Diseases - Diet therapy |
| Soggetto non controllato |
epilepsy
glioblastoma multiforme ADHD prefrontal cortex regainers functional neuroimaging malignant glioma nutrients caffeine children inflammation working memory cytokines modified Atkins diet fish intake insulin resistance transpulmonary administration obesity maintainers electroencephalography Alzheimer's disease omega-3 fatty acids diet-deficient weight loss maintenance neural processing hippocampal neurogenesis |
| ISBN | 3-03921-651-1 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | Diet in Brain Health and Neurological Disorders |
| Record Nr. | UNINA-9910367747803321 |
| MDPI - Multidisciplinary Digital Publishing Institute, 2019 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Modern Developments in Transcranial Magnetic Stimulation (TMS) - Applications and Perspectives in Clinical Neuroscience
| Modern Developments in Transcranial Magnetic Stimulation (TMS) - Applications and Perspectives in Clinical Neuroscience |
| Autore | Sollmann Nico |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 electronic resource (286 p.) |
| Soggetto topico | Medical equipment & techniques |
| Soggetto non controllato |
brain stimulation
fiber tractography glioblastoma multiforme gray matter language mapping navigated transcranial magnetic stimulation Autism spectrum disorder evoked and induced gamma oscillations EEG TMS oddball task reaction time aberrant and repetitive behaviors repetition suppression neuroplasticity transcranial magnetic stimulation paired associative stimulation nTMS intensive care motor mapping ICU neurocritical care neuromonitoring functional mapping motor evoked potentials aging excitability connectivity plasticity brain tumor bilingual language preoperative mapping case report CD73 adenosine A2AR A1R neuroinflammation theta-burst stimulation rTMS purinergic signaling electric field eloquent cortex motor threshold neuronavigation presurgical evaluation chronic pain low back pain repetitive transcranial magnetic stimulation neuromodulation dorsolateral prefrontal cortex primary motor cortex picture naming bihemispheric action naming object naming memory hippocampus brain networks non-invasive brain stimulation mild cognitive impairment Alzheimer's disease stroke aphasia iTBS fMRI rehabilitation alpha oscillations functional connectivity source reconstruction MEG EEG state-dependent TMS |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | Modern Developments in Transcranial Magnetic Stimulation |
| Record Nr. | UNINA-9910580203303321 |
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Sollmann Nico
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Novel Treatment Strategies for Glioblastoma
| Novel Treatment Strategies for Glioblastoma |
| Autore | Stylli Stanley |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 electronic resource (268 p.) |
| Soggetto topico | Medicine |
| Soggetto non controllato |
glioblastoma
glioma temozolomide radiotherapy immunotherapy novel therapy personalized treatment drug repurposing invasion invadopodia ion channels gene therapy viral vectors brain tumor nanomedicine cancer stem cell targeted therapy brain cancer cell cycle differentiation proliferation RAS SRGAP2 stem cell TP53 glioblastoma multiforme GBM nerve/glial antigen 2 NG2 CK2 CX-4945 migration CRISPR/Cas9 anticancer anti-angiogenesis thyrointegrin αvβ3 PEG triazole tetrac P-bi-TAT P-m-TAT tetrac one-carbon metabolism de novo purine synthesis metabolic reprogramming metabolic treatment vaccine immune checkpoint inhibitors chimeric antigen receptor (CAR) T cells glioblastoma (GB) prolyl-oligopeptidase (POP) vascular endothelial growth factor (VEGF) transforming growth factor-β (TGF-β) angiopoietin (Ang) endothelial nitric oxide synthase (eNOS) newly diagnosed glioblastoma recurrent glioblastoma new trial design drug-inducible gene expression Mardepodect Regorafenib drug targets tumor antigens renin-angiotensin system pluripotent stem cells organoids cancer stem cells cancer stem cell niche tumor microenvironment |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557363703321 |
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Stylli Stanley
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Nucleic Acid Architectures for Therapeutics, Diagnostics, Devices and Materials
| Nucleic Acid Architectures for Therapeutics, Diagnostics, Devices and Materials |
| Autore | Afonin Kirill |
| Pubbl/distr/stampa | MDPI - Multidisciplinary Digital Publishing Institute, 2019 |
| Descrizione fisica | 1 electronic resource (186 p.) |
| Soggetto non controllato |
cotranscriptional folding
RNA conditionally activated i-motif DNA spinal cord tumor fluorescence dynamic stability functional RNA ribozyme biological media RNA aptamers gene therapy biosensors viral vector ganciclovir RNA self-assembly RNA nanoparticle gene delivery riboswitch non-viral gene delivery NANPs silver nanoclusters small-angle neutron scattering contrast variation aptamers RNA logic fluorogenic RNA glioblastoma multiforme RNA interference nucleic acid nanoparticles immunostimulation aggregation small-angle X-ray scattering non-viral vector light-up aptamer nucleic acid therapeutic live-cell imaging DNA nanotechnology nucleic acid computing nanopores structural characterization siRNA suicide gene therapy nucleic acid nanoparticle cytosine rich sequences RNA nanotechnology logic gates serum conditional activation |
| ISBN | 3-03921-260-5 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910367569503321 |
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Afonin Kirill
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| MDPI - Multidisciplinary Digital Publishing Institute, 2019 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Numerical Simulation in Biomechanics and Biomedical Engineering
| Numerical Simulation in Biomechanics and Biomedical Engineering |
| Autore | Malvè Mauro |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 electronic resource (300 p.) |
| Soggetto topico | Technology: general issues |
| Soggetto non controllato |
finite element analysis
shoulder implant stability implant design reverse shoulder arthroplasty micromotion in-silico 3D model cardiac cell cardiac muscle tissue cardiomyocyte electrical stimulation copulas design of experiments glioblastoma multiforme mathematical modelling Morse theory topological data analysis machine learning time series smart driving fixed points manifolds divergence hemodynamics computational fluid dynamics overlap malapposition stent stenosis thrombosis radioembolization liver cancer hepatic artery computational cost analysis personalized medicine patient specific finite element method implicit FEM explicit FEM skeletal muscle biomechanics mathematical model cell dynamics bone physiology bone disorders aortic dissection delamination tests cohesive zone model porcine aorta vascular mechanics foot finite element method foot and ankle model shared nodes separated mesh plantar pressure finite element modelling bone tissue engineering 3D scaffold additive manufacturing potential swirling flow Navier–Stokes equations unsteady swirling flow tornado-like jets haemorheology blood flow modelling particle transport numerical fluid mechanics tracheobronchial stent parametric model 3D printing customized prosthesis |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557314603321 |
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Malvè Mauro
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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