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Application of Bioinformatics in Cancers
| Application of Bioinformatics in Cancers |
| Autore | Brenner J. Chad |
| Pubbl/distr/stampa | MDPI - Multidisciplinary Digital Publishing Institute, 2019 |
| Descrizione fisica | 1 online resource (418 p.) |
| Soggetto topico | Biotechnology |
| Soggetto non controllato |
activation induced deaminase
AID/APOBEC alternative splicing anti-cancer artificial intelligence bioinformatics Bioinformatics tool biomarker discovery biomarker signature biomarkers biostatistics brain brain metastases breast cancer breast cancer detection breast cancer prognosis Bufadienolide-like chemicals cancer cancer biomarker cancer biomarkers cancer CRISPR cancer modeling cancer prognosis cancer treatment cancer-related pathways cell-free DNA chemotherapy circulating tumor DNA (ctDNA) classification clinical/environmental factors colorectal cancer comorbidity score Computational Immunology concatenated deep feature copy number aberration copy number variation curation curative surgery datasets decision support systems deep learning denoising autoencoders differential gene expression analysis diseases genes DNA DNA sequence profile drug resistance epigenetics erlotinib estrogen extreme learning false discovery rate feature extraction and interpretation feature selection firehose functional analysis gefitinib gene expression analysis gene inactivation biomarkers gene loss biomarkers gene signature extraction genomic instability GEO DataSets head and neck cancer health strengthening herb hierarchical clustering analysis high-throughput analysis histopathological imaging histopathological imaging features HNSCC hormone sensitive cancers HP hTERT imaging independent prognostic power interaction intratumor heterogeneity knockoffs KRAS mutation locoregionally advanced machine learning meta-analysis methylation microarray miRNA miRNAs mitochondrial metabolism mixture of normal distributions molecular mechanism molecular subtypes Monte Carlo mortality multiple-biomarkers mutable motif mutation Neoantigen Prediction network analysis Network Analysis network pharmacology network target neurological disorders next generation sequencing observed survival interval omics omics profiles oral cancer ovarian cancer overall survival pancreatic cancer pathophysiology PD-L1 precision medicine predictive model protein R package RNA self-organizing map single-biomarkers single-cell sequencing skin cutaneous melanoma somatic mutation StAR steroidogenic enzymes survival analysis TCGA TCGA mining telomerase telomeres The Cancer Genome Atlas traditional Chinese medicine transcriptional signatures treatment de-escalation tumor tumor infiltrating lymphocytes tumor microenvironment variable selection |
| ISBN | 3-03921-789-5 |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910367743403321 |
Brenner J. Chad
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| MDPI - Multidisciplinary Digital Publishing Institute, 2019 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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DNA Replication Stress / Robert M. Brosh
| DNA Replication Stress / Robert M. Brosh |
| Autore | Brosh Robert M |
| Pubbl/distr/stampa | MDPI - Multidisciplinary Digital Publishing Institute, 2019 |
| Descrizione fisica | 1 electronic resource (368 p.) |
| Soggetto topico | Biology, life sciences |
| Soggetto non controllato |
Werner Syndrome
A549 cells epigenetic neurodegeneration Genome integrity adaptation cellular senescence genome instability Werner Syndrome Protein lipofuscin cell cycle checkpoints exonuclease 1 template-switching energy metabolism mutation frequency DNA replication fork regression motor neuron disease Microsatellites Alzheimer's disease chromatin remodeler repair of DNA damage AP site analogue mutagens replication timing Thermococcus eurythermalis nucleolar stress gene expression mutations spectra origin firing Fanconi Anemia superfamily 2 ATPase DNA translocation DNA repair SSB signaling homologous recombination common fragile sites 8-chloro-adenosine replication genome stability mutagenicity fork reversal multiple sclerosis non-B DNA protein stability heterogeneity ubiquitin SenTraGorTM (GL13) replication restart EdU ?-arrestin NER aging SSB end resection oxidative stress ATR dormant origins R loops DNA damage response Difficult-to-Replicate Sequences DNA double-strand repair endonuclease IV ALS double strand break repair premature aging replication stress EXO1 POL? translesion synthesis strand displacements G2-arrest DNA replication pattern SSB repair genome integrity G protein-coupled receptor kinase interacting protein 2 (GIT2) MMR replicative stress senolytics spacer interactome ATR-Chk1 DDR pathway C9orf72 replication fork restart translesion DNA synthesis DNA damage mismatch repair DNA replication stress DNA helicase Polymerase kappa DNA fiber assay H1299 cells TLS APE2 ageing cell death chromosome TopBP1 barley clock proteins post-translational modification 8-oxoG S phase ataxia telangiectasia mutated (ATM) G protein-coupled receptor (GPCR) Polymerase eta cancer G protein-coupled receptor kinase (GRK) helicase genomic instability Parkinson's disease nucleotide excision repair SupF |
| ISBN |
9783039213900
3039213903 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910367564903321 |
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Brosh Robert M
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| MDPI - Multidisciplinary Digital Publishing Institute, 2019 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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