Autore	Brosh Robert M
Pubbl/distr/stampa	MDPI - Multidisciplinary Digital Publishing Institute, 2019
Descrizione fisica	1 electronic resource (368 p.)
Soggetto topico	Biology, life sciences
Soggetto non controllato	Werner Syndrome A549 cells epigenetic neurodegeneration Genome integrity adaptation cellular senescence genome instability Werner Syndrome Protein lipofuscin cell cycle checkpoints exonuclease 1 template-switching energy metabolism mutation frequency DNA replication fork regression motor neuron disease Microsatellites Alzheimer's disease chromatin remodeler repair of DNA damage AP site analogue mutagens replication timing Thermococcus eurythermalis nucleolar stress gene expression mutations spectra origin firing Fanconi Anemia superfamily 2 ATPase DNA translocation DNA repair SSB signaling homologous recombination common fragile sites 8-chloro-adenosine replication genome stability mutagenicity fork reversal multiple sclerosis non-B DNA protein stability heterogeneity ubiquitin SenTraGorTM (GL13) replication restart EdU ?-arrestin NER aging SSB end resection oxidative stress ATR dormant origins R loops DNA damage response Difficult-to-Replicate Sequences DNA double-strand repair endonuclease IV ALS double strand break repair premature aging replication stress EXO1 POL? translesion synthesis strand displacements G2-arrest DNA replication pattern SSB repair genome integrity G protein-coupled receptor kinase interacting protein 2 (GIT2) MMR replicative stress senolytics spacer interactome ATR-Chk1 DDR pathway C9orf72 replication fork restart translesion DNA synthesis DNA damage mismatch repair DNA replication stress DNA helicase Polymerase kappa DNA fiber assay H1299 cells TLS APE2 ageing cell death chromosome TopBP1 barley clock proteins post-translational modification 8-oxoG S phase ataxia telangiectasia mutated (ATM) G protein-coupled receptor (GPCR) Polymerase eta cancer G protein-coupled receptor kinase (GRK) helicase genomic instability Parkinson's disease nucleotide excision repair SupF
ISBN	9783039213900 3039213903
Formato	Materiale a stampa
Livello bibliografico	Monografia
Lingua di pubblicazione	eng
Record Nr.	UNINA-9910367564903321

Autore	Martins Cesar
Pubbl/distr/stampa	MDPI - Multidisciplinary Digital Publishing Institute, 2019
Descrizione fisica	1 online resource (254 p.)
Soggetto topico	Biology, life sciences
Soggetto non controllato	?s additional chromosomes Apodemus peninsulae B chromosome B chromosomes B morphotypes centromere chromosome evolution chromosome polymorphism controlling element coverage ratio analysis cytogenetics de novo centromere formation DNA composition DNA copy number variation dot-like (micro) Bs drive Drosophila epigenetics euchromatin degradation evolution extra chromosomes FISH (fluorescence in situ hybridisation) fluorescent in situ hybridization genes genome evolution genome instability genomics GISH (genomic in situ hybridisation) grasshoppers heterochromatin host/parasite interaction inactivation interphase nucleus karyotype evolution karyotypes karyotypic characteristics maize B chromosome mammals maternal X chromosome microdissected DNA probes mobile element n/a next-generation sequencing organelle DNA origin Orthoptera parent-of-origin effects paternal X chromosome population analysis Prospero autumnale complex reactivation repeat clusters RepeatExplorer repetitive DNA repetitive elements ribosomal DNA RNA-Seq satellite DNA sSMC supernumerary supernumerary chromosomal segments (SCS) evolution supernumerary chromosome supernumerary chromosomes supernumerary elements tandem repeats teleost transcription of heterochromatin transmission whole genome resequencing
ISBN	3-03897-787-X
Formato	Materiale a stampa
Livello bibliografico	Monografia
Lingua di pubblicazione	eng
Record Nr.	UNINA-9910346673503321

Autore	Antonio Porro
Pubbl/distr/stampa	Frontiers Media SA, 2017
Descrizione fisica	1 online resource (306 p.)
Collana	Frontiers Research Topics
Soggetto topico	Genetics (non-medical)
Soggetto non controllato	DNA Damage DNA damage response DNA Repair genome instability Genome integrity
Formato	Materiale a stampa
Livello bibliografico	Monografia
Lingua di pubblicazione	eng
Record Nr.	UNINA-9910220034503321