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Access to Medicines and Vaccines : Implementing Flexibilities under Intellectual Property Law
| Access to Medicines and Vaccines : Implementing Flexibilities under Intellectual Property Law |
| Autore | Correa Carlos M |
| Pubbl/distr/stampa | Cham, : Springer International Publishing AG, 2021 |
| Descrizione fisica | 1 online resource (x, 369 pages) : color illustrations |
| Altri autori (Persone) | HiltyReto M |
| Soggetto topico |
Patent medicines
Patent medicines - Law and legislation |
| Soggetto non controllato |
access to medicines
TRIPS Intellectual Property Exhaustion Compulsory license Pharmaceutical Patents genome editing Open Access |
| ISBN | 3-030-83114-0 |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | Interpreting the Flexibilities Under the TRIPS Agreement / Carlos M. Correa -- Intellectual Property Exhaustion and Parallel Imports of Pharmaceuticals : a Comparative and Critical Review / Irene Calboli -- Compulsory Licenses and Government Use : Challenges and Opportunities / Yousuf A. Vawda -- Access to CRISPR Genome Editing Technologies : Patents, Human Rights and the Public Interest / Duncan Matthews -- Bolar Exception / Viviana Munoz Tellez -- Patent Oppositions in India / Sandeep Kanak Rathod -- Protection of Clinical Test Data and Public Health : A Proposal to End the Stronghold of Data Exclusivity / Ellen 't Hoen -- Courts and Pharmaceutical Patents : From Formalist Positivism to the Emergence of a Global Law / Calixto Salomao Filho, Vitor Henrique Pinto Ido -- Robust Patent Examination or Deep Harmonization? Cooperation and Work Sharing Between Patent Offices / Nirmalya Syam -- Intellectual Property Rights (IPRs), Competition Law and Excessive Pricing of Medicines / Mor Bakhoum -- The Impact of 'TRIPS-Plus' Rules on the Use of TRIPS Flexibilities : Dealing with the Implementation Challenges / Mohammed El Said -- Patent Linkages and Its Impact on Access to Medicines : Challenges, Opportunities for Developing Countries / K.D. Raju. |
| Record Nr. | UNINA-9910504284403321 |
Correa Carlos M
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| Cham, : Springer International Publishing AG, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Advances in Cereal Crops Breeding
| Advances in Cereal Crops Breeding |
| Autore | Loskutov Igor G |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 electronic resource (196 p.) |
| Soggetto topico | Research & information: general |
| Soggetto non controllato |
maize
density tolerance combining ability gene effects genetic diversity rice salinity submergence tolerance blast SSR markers PCR analysis long non-coding RNAs seed development Nanopore sequencing retrotransposons triticale prediction accuracy mixed linear and Bayesian models machine learning algorithms training set size and composition parametric and nonparametric models drought stress dendrogram barley breeding marker-assisted selection genes genetic resources genome editing health benefits metabolomics oat QTL wheat Triticum aestivum L. QMrl-7B root traits grain yield nitrogen use efficiency GWAS salinity tolerance Vietnamese landraces abiotic stress root auxin YUCCA PIN proteomics mass spectrometry |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557363803321 |
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Loskutov Igor G
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Advances in Molecular Breeding of Vegetable Crops
| Advances in Molecular Breeding of Vegetable Crops |
| Autore | Zhang Yuyang |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 electronic resource (242 p.) |
| Soggetto topico |
Research & information: general
Biology, life sciences Technology, engineering, agriculture |
| Soggetto non controllato |
pepper
Capsicum annuum Phytophthora capsici high-density genetic map QTL Capcicum annuum L. RNA-Seq nitrogen-use efficiency low-nitrogen tolerance CaHSP18.1a gene silencing transgenic Arabidopsis heat stress gene expression pumpkin simple sequence repeat (SSR) syntenic relationship cross-species markers population structure eggplant heat shock factor (Hsf) heat shock protein (Hsp) thermotolerance C. frutescens SSR germplasm genetic diversity CRISPR/Cas gene knockout genome editing germplasm resource precision editing regulatory framework trait improvement Brassica oleracea broccoli candidate gene anthocyanin allelochemicals VOCs properties VOCs action VOCs detection green agriculture progress genetic researches molecular breeding transcriptomics transcription factor heritability genetic advance multi-trait selection principal component analysis HRM molecular marker phylogenetic analysis RNA sequencing SCAR SNP |
| ISBN | 3-0365-5790-3 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910637793303321 |
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Zhang Yuyang
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Bacillus thuringiensis Toxins: Functional Characterization and Mechanism of Action
| Bacillus thuringiensis Toxins: Functional Characterization and Mechanism of Action |
| Autore | Bel Yolanda |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 electronic resource (340 p.) |
| Soggetto topico | Research & information: general |
| Soggetto non controllato |
Bacillus thuringiensis
Plutella xylostella Cry1Ac resistance trypsin-like midgut protease protoxin activation Spodoptera spp., Helicoverpa armigera Mamestra brassicae Anticarsia gemmatalis Ostrinia furnacalis Cry2Ab toxin Bombyx mori ATP-binding cassette subfamily a member 2 (ABCA2) genome editing transcription activator-like effector-nucleases (TALENs) HEK293T cell functional receptor Vip3Aa lysosome mitochondria apoptosis Sf9 cells Cry1Ab oligomer formation Sf21 cell line Ostrinia nubilalis Lobesia botrana Leptinotarsa decemlineata bioassay Cyt2Aa2 toxin protein-lipid binding erythrocyte membrane AFM QCM-D Asian corn borer ABCC2 CRISPR/Cas9 Cry1Fa resistance chitin-binding protein adhesion peritrophic matrix Vip3A Spodoptera litura site-directed mutagenesis Cry Cyt parasporins S-layer proteins Vip Sip membrane receptors insecticidal activity anticancer activity Aedes aegypti minor proteins synergy mosquito control Bti Spodoptera frugiperda cadherin mode of action of Cry toxin insecticidal proteins insect resistance tobacco budworm Bacillus thuringiensis proteins coleopteran pests structure mode of action 3D-structure biological control antimicrobial peptide gut microbiota vegetative insecticidal proteins pyramids 3D-Cry toxins in vitro evolution rational design toxin enhancement |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | Bacillus thuringiensis Toxins |
| Record Nr. | UNINA-9910557646103321 |
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Bel Yolanda
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Berry Crop Production and Protection
| Berry Crop Production and Protection |
| Autore | Debnath Samir |
| Pubbl/distr/stampa | MDPI - Multidisciplinary Digital Publishing Institute, 2019 |
| Descrizione fisica | 1 electronic resource (158 p.) |
| Soggetto non controllato |
ascorbic acid
methyl anthranilate crispy fruit work-related musculoskeletal disorders abiotic stress frequency blueberry harvesting inflatable tubemen dB genome editing biomass Fragaria ethephon sound waves ergonomics intervention bird deterrent Michigan quantitative genetics Vaccinium ripening firmness chlormequat chloride cell wall fruit quality parameters molecular markers breeding |
| ISBN | 3-03921-095-5 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910346686203321 |
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Debnath Samir
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| MDPI - Multidisciplinary Digital Publishing Institute, 2019 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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EmbryoGenetics
| EmbryoGenetics |
| Autore | Simón Carlos |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 electronic resource (176 p.) |
| Soggetto topico | Research & information: general |
| Soggetto non controllato |
extracellular vesicles
exosomes microvesicles apoptotic bodies DNA preimplantation embryos murine blastocysts embryo uterus window of implantation PGT-A PGT-SR mosaicism embryo genetics chromosomal abnormality preimplantation genetic testing PGT-P polygenic risk scoring genomic index relative risk reduction combined preimplantation genetic testing Preimplantation genetic testing for monogenic disorders (PGT-M) Preimplantation genetic testing for aneuploidy assessment (PGT-A) Autosomal dominant polycystic kidney disease (ADPKD) male infertility advanced maternal age aneuploidy NGS segmental translocations monogenic disease multiplex PCR SNP array genome editing genetic diseases embryos vitrification ovarian response female age genetic testing reproductive health next-generation sequencing whole exome sequencing perinatal care infertility aneuploidies polygenic disease blastocyst endometrium implantation |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557725303321 |
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Simón Carlos
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Fast-Growing Trees Species-Opportunities and Risks for Sustainable Agricultural and Forest Land Use Systems
| Fast-Growing Trees Species-Opportunities and Risks for Sustainable Agricultural and Forest Land Use Systems |
| Autore | Landgraf Dirk |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 electronic resource (204 p.) |
| Soggetto topico |
Research & information: general
Biology, life sciences Forestry & related industries |
| Soggetto non controllato |
woody biomass crops
bioenergy biodiversity species richness flora vascular plants short rotation coppices poplars willows feeding simulation defoliation herbivory short rotation coppice phosphatase activity nutrient content growth stages biomass willow Salix capacity European larch fast-growing trees plantations plantation area poplar cultivar "Hybrid 275" sown area biomass production life cycle assessment climate impact soil organic carbon genotypic difference CRISPR/Cas9 genome editing Populus INRA 717-1B4 pyramidal plant habitus leaf petiole angle branch angle nitrogen phosphorus carbon physiology F. mandshurica Robinia pseudoacacia L. photosynthetic vitality chlorophyll and phenol content nutrition supply dry matter yield land reclamation spring pruning year-long pruning branching angle diversion of sprout dry matter losses poplar wood chips laboratory scale cultivable saproxylic microbiota |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910580208203321 |
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Landgraf Dirk
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Genetics of Animal Health and Disease in Livestock
| Genetics of Animal Health and Disease in Livestock |
| Autore | Castiglioni Bianca |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 electronic resource (188 p.) |
| Soggetto topico |
Research & information: general
Technology: general issues |
| Soggetto non controllato |
broiler
thermal manipulation antioxidant heat stress cold stress Bovine Viral Diarrhea Virus RNA-Seq Transcriptome analysis Holstein cattle sheep intersex whole-genome resequencing copy number variation forming mechanism dairy cattle diseases innate immune system metabolic stress microbiome mastitis bovine mammary epithelial cells inflammatory cytokines NF-κB signaling PRRs TLRs Piemontese breed arthrogryposis macroglossia genetic model TLR3 TLR4 TLR7 foals immunostimulation gene expression bovine mastitis JAK-STAT pathway JAK2 STATs SOCS3 immunity milk production DNA methylation high-fat diet rabbits next generation sequencing transcriptomics bioinformatics genome editing disease resistance livestock dairy cattle teat-end hyperkeratosis udder health somatic cell genetic correlation selection response Holstein Friesian cattle mastitis resistance candidate genes SNP selection next-generation sequencing |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557697903321 |
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Castiglioni Bianca
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Genetics of Hearing Impairment
| Genetics of Hearing Impairment |
| Autore | del Castillo Ignacio |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 electronic resource (314 p.) |
| Soggetto topico |
Research & information: general
Biology, life sciences Genetics (non-medical) |
| Soggetto non controllato |
inner ear
hearing impairment gene identification disease-causing mutations genetic epidemiology genotype&ndash phenotype correlations pathophysiological mechanisms omics genome editing gene therapy |
| ISBN | 3-0365-5224-3 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910637793003321 |
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del Castillo Ignacio
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Global Impact of Ergot Alkaloids
| Global Impact of Ergot Alkaloids |
| Autore | Klotz James L |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 electronic resource (252 p.) |
| Soggetto topico |
Medicine
Medical toxicology |
| Soggetto non controllato |
ergot alkaloids
strain improvement UV EMS Penicillium citrinum response surface methodology PBD BBD integrative interactomics integrome metabolomics microbiome tall fescue Epichloë coenophiala fescue toxicosis ergot alkaloid occurrence sclerotia cereals LC-MS/MS correlation survey beef cattle endophyte ergot alkaloid isoflavone metabolites genetic tolerance cytokines cow productivity CRISPR/Cas9 non-transgenic engineered fungi genome editing genome sequencing MinION nanopore secondary metabolites endophyte transmission livestock safety insect testing quality control alkaloid profile single nucleotide polymorphism milk production calf growth acute ergot exposure ergot toxicity sheep vasoconstriction adrenergic receptors ergot ethnopharmacology abortion childbirth ergovaline horse pastures pregnant mares species composition ergot fungi gene divergence gene diversity indole diterpenes phylogeny Claviceps purpurea fungal plant pathogen biosynthetic gene cluster mycotoxins untargeted metabolomics mass spectrometry blood vessel myograph serotonin |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910566483603321 |
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Klotz James L
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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