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Advance in the Treatment of Pediatric Leukemia
| Advance in the Treatment of Pediatric Leukemia |
| Autore | Handgretinger Rupert |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 electronic resource (300 p.) |
| Soggetto topico |
Research & information: general
Chemistry |
| Soggetto non controllato |
acute lymphoblastic leukemia
pediatric advances diagnosis treatment immunotherapy bispecific T-cell engager (BiTE) BCP-ALL leukemia TRAIL antibody Fc-engineering xenograft CD19 juvenile myelomonocytic leukemia RAS signaling hematopoietic stem cell transplantation 5-azacitidine myelodysplastic/myeloproliferative disorders targeted therapy ADC antibody-drug conjugate pediatric leukemia ALL AML allogeneic stem cell transplantation acute myeloid leukemia minimal residual disease conditioning regimen alternative donors B-ALL DUX4 IKZF1 PAX5 Ph-like ZNF384 NUTM1 T-ALL NOTCH1 BCL11B transcriptome genome chronic myeloid leukemia CML tyrosine kinase inhibitor immunizations COVID-19 childhood acute lymphoblastic leukemia low-risk ALL risk-stratified treatment treatment related toxicity L-asparaginase acute pancreatitis polymorphism SNV ABCC4 CFTR other extramedullary relapse lymphoblastic leukemia children prognosis evolution of CAR T cells FDA-approved CAR products TcR versus CAR limitations and complications of CAR T cell therapy future directions of CAR T cell therapy |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910576878903321 |
Handgretinger Rupert
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Chagas Disease
| Chagas Disease |
| Autore | Heukelbach Jorg |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 electronic resource (150 p.) |
| Soggetto topico | Medicine |
| Soggetto non controllato |
Chagas disease
neglected tropical diseases migration healthcare rights mucosal leishmaniasis co-infection antimoniate therapy cardiomyopathy myocardial fibrosis myocardial sympathetic denervation inflammation sudden death cardiac magnetic resonance radionuclide imaging SPECT-CT PET-CT heart disease electrocardiogram disease progression stroke risk assessment Trypanosoma cruzi Triatoma infestans parasite prevalence coprophagy human illness neglected tropical disease global financing annual funding investments disease notification public policy neglected topical diseases healthcare access chagasic cardiomyopathy heart transplantation Chagas disease reactivation cardiac allograft rejection treatment of reactivation genome parasite neglected diseases heart transplant chagas disease reactivation Cohort studies Neglected diseases Dynamic programming cost of illness premature efficiency organizational life expectancy American trypanosomiasis Trypanosoma cruzi infection public health epidemiology prevention and control surveillance clinical research One Health |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557598203321 |
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Heukelbach Jorg
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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DNA [[electronic resource] ] : promise and peril / / Linda L. McCabe and Edward R.B. McCabe ; with a foreword by Victor A. McKusick
| DNA [[electronic resource] ] : promise and peril / / Linda L. McCabe and Edward R.B. McCabe ; with a foreword by Victor A. McKusick |
| Autore | McCabe Linda L. <1947-> |
| Pubbl/distr/stampa | Berkeley, : University of California Press, c2008 |
| Descrizione fisica | 1 online resource (357 p.) |
| Disciplina | 616/.042 |
| Altri autori (Persone) | McCabeEdward R. B |
| Soggetto topico |
Medical genetics - Moral and ethical aspects
Genetic engineering - Moral and ethical aspects |
| Soggetto non controllato |
abuse
abusive academic biology business civil rights cloning commodity cultural history cultural studies culture discovery discrimination dna ethics ethnicity evolution genetic revolution genetics genome genomics human centered biology judgement legal issues medical science medicine reproduction scholarly science scientific social history social issues social studies |
| ISBN |
1-281-38549-2
9786611385491 0-520-93393-1 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | DNA sequence does not equal destiny -- What is genomics? -- Genetic determinism -- The evolution and deconstruction of human-centered biology -- Race and ethnicity : your history is written in your genes -- Gender as a spectrum, not a dichotomy -- Genome-based forensics -- When genes belong to groups and not individuals -- Genes as commodities : ownership of genes by business interests -- Protection against genetic discrimination : the new civil right -- Reproductive technologies : on the road to designer babies? -- Reproductive cloning : from farm animals to pets to humans? -- Therapeutic cloning and regenerative medicine -- Gene therapy : can the promise be fulfilled? -- Large population assessments : the foundation for genomic medicine -- Hidden destiny : unbounded by your DNA. |
| Record Nr. | UNINA-9910782013503321 |
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McCabe Linda L. <1947->
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| Berkeley, : University of California Press, c2008 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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DNA [[electronic resource] ] : promise and peril / / Linda L. McCabe and Edward R.B. McCabe ; with a foreword by Victor A. McKusick
| DNA [[electronic resource] ] : promise and peril / / Linda L. McCabe and Edward R.B. McCabe ; with a foreword by Victor A. McKusick |
| Autore | McCabe Linda L. <1947-> |
| Edizione | [1st ed.] |
| Pubbl/distr/stampa | Berkeley, : University of California Press, c2008 |
| Descrizione fisica | 1 online resource (357 p.) |
| Disciplina | 616/.042 |
| Altri autori (Persone) | McCabeEdward R. B |
| Soggetto topico |
Medical genetics - Moral and ethical aspects
Genetic engineering - Moral and ethical aspects |
| Soggetto non controllato |
abuse
abusive academic biology business civil rights cloning commodity cultural history cultural studies culture discovery discrimination dna ethics ethnicity evolution genetic revolution genetics genome genomics human centered biology judgement legal issues medical science medicine reproduction scholarly science scientific social history social issues social studies |
| ISBN |
1-281-38549-2
9786611385491 0-520-93393-1 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | DNA sequence does not equal destiny -- What is genomics? -- Genetic determinism -- The evolution and deconstruction of human-centered biology -- Race and ethnicity : your history is written in your genes -- Gender as a spectrum, not a dichotomy -- Genome-based forensics -- When genes belong to groups and not individuals -- Genes as commodities : ownership of genes by business interests -- Protection against genetic discrimination : the new civil right -- Reproductive technologies : on the road to designer babies? -- Reproductive cloning : from farm animals to pets to humans? -- Therapeutic cloning and regenerative medicine -- Gene therapy : can the promise be fulfilled? -- Large population assessments : the foundation for genomic medicine -- Hidden destiny : unbounded by your DNA. |
| Record Nr. | UNINA-9910816018903321 |
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McCabe Linda L. <1947->
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| Berkeley, : University of California Press, c2008 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Enological Repercussions of Non-Saccharomyces Species
| Enological Repercussions of Non-Saccharomyces Species |
| Autore | Morata Antonio |
| Pubbl/distr/stampa | MDPI - Multidisciplinary Digital Publishing Institute, 2019 |
| Descrizione fisica | 1 electronic resource (218 p.) |
| Soggetto non controllato |
wine acidity
pulcherrimin glycosidases Lactobacillus plantarum Saccharomycodes ludwigii sparkling wine processing foods non-Saccharomyces taxonomy Candida stellate wine quality Candida stellata non-Saccharomyces yeast Brettanomyces bruxellensis flavor complexity Schizosaccharomyces pombe Wickerhamomyces anomalus Stermerella bacillaris mixed cultures fermentation oenological uses winemaking re-fermentation Zygosaccharomyces rouxii Torulaspora delbrueckii genetic improvement Zygotorulaspora florentina maloalcoholic fermentation high-ethanol mixed starters yeast wines non-Saccharomyces yeasts aroma compounds spoilage yeasts' control metabolism acetate esters Pichia anomala wine sequential fermentations spoilage-control enzymes yeast dominance acidification ageing-on-lees Kluyveromyces thermotolerans co-fermentation biotechnological applications stable pigments ecology Pichia kudriavzevii Lachancea thermotolerans Metschnikowia pulcherrima biocontrol S. ludwigii Candida intermedia nitrogen yeast inoculation volatile acidity off-flavors malolactic bacteria wine safety genome Aureobasidium pullulans viticulture anthocyanin aroma antimicrobial peptides |
| ISBN | 3-03921-559-0 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910367749903321 |
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Morata Antonio
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| MDPI - Multidisciplinary Digital Publishing Institute, 2019 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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G-quadruplex and Microorganisms
| G-quadruplex and Microorganisms |
| Autore | Richter Sara N |
| Pubbl/distr/stampa | MDPI - Multidisciplinary Digital Publishing Institute, 2019 |
| Descrizione fisica | 1 electronic resource (208 p.) |
| Soggetto non controllato |
bacteria
folding co-translational refolding RecQ helicase regulatory element conformational dynamics G4Hunter NDPK fluorescence pseudorabies virus Epstein-Barr virus (EBV) structure-activity relationship PhenDC3 eukaryotic hosts Herpesvirus translation suppression turn-on ligands co-transcriptional folding Herpesviridae G-quadruplex nucleoside diphosphate kinase nucleic acids nucleic acids conformation bioinformatics protein–DNA interaction aptamers deinococcus Alphaherpesvirinae EBNA1 G4 virus human papillomaviruses S. cerevisiae genome stability G-quadruplexes metastable structure genome evolution pyridostatin alphaherpesviruses structure protozoa genome G-quadruplex ligand NMR microbes DNA protein-mRNA interactions G-quadruplex formation immediate early promoters |
| ISBN | 3-03921-244-3 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910367567503321 |
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Richter Sara N
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| MDPI - Multidisciplinary Digital Publishing Institute, 2019 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Geometries of the Living : Inaugural Lecture delivered on Thursday 4 October 2007 / / Alain Prochiantz
| Geometries of the Living : Inaugural Lecture delivered on Thursday 4 October 2007 / / Alain Prochiantz |
| Autore | Prochiantz Alain |
| Pubbl/distr/stampa | Paris, : Collège de France, 2016 |
| Altri autori (Persone) |
CorvolPierre
ProchiantzAlain |
| Soggetto topico |
History & Philosophy Of Science
biology development genetics morphogenesis genome life science proteins |
| Soggetto non controllato |
genome
development biology genetics morphogenesis proteins life science |
| ISBN | 2-7226-0437-X |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910136385603321 |
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Prochiantz Alain
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| Paris, : Collège de France, 2016 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Kinetoplastid Genomics and Beyond
| Kinetoplastid Genomics and Beyond |
| Autore | Requena Jose M |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 electronic resource (251 p.) |
| Soggetto topico |
Research & information: general
Biology, life sciences |
| Soggetto non controllato |
trypanosomatids
yeasts trypanosomatids genome cell cycle phases S-phase duration DNA replication replication origins neglected tropical diseases Leishmania Trypanosoma cruzi Trypanosoma brucei drug discovery in vitro models in vivo models genomics drug resistance Leishmania infantum proteome post-translational modifications (PTMs) proteogenomics mass spectrometry Retrotransposon Hot Spot (RHS) multigene family chromosome distribution recombination gene mosaic structure evolution nuclear protein Leishmania braziliensis reverse genetics CRISPR–Cas9 gene targeting phenotyping heat shock proteins Trypanosoma cruzi strain sequencing methods genome plasticity gene expression trans-sialidases mucins SENP Ulp2 SUMO CRISPR protease genome repeats 3′UTR multigenic family Leishmania donovani whole-genome sequencing (WGS) transcriptome artemisinin drug resistance Leishmania viruses phylogeny coevolution endosymbiont protozoan viruses transcriptome assembly transcriptional regulation ontology network co-expression network taxonomic analysis database contamination kleptoplastidy |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557679003321 |
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Requena Jose M
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Molecular Pathways in Cancers
| Molecular Pathways in Cancers |
| Autore | Cristóbal Ion |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 electronic resource (284 p.) |
| Soggetto topico |
Medicine
Oncology |
| Soggetto non controllato |
actin cytoskeletal reorganization
breast cancer CD99 agonist EGFR dimerization endocytosis FAK dephosphorylation PTPN12 Rac1 RhoA tripeptide OMD PRELP tumor suppression gene bladder cancer initiation tight junction partial EMT tousled-like kinase (TLK) NIMA-related kinase 1 (NEK1) yes-associated protein 1 (YAP1) thioridazine (THD) MS-determined phosphopeptides human immunodeficiency virus type 1 epithelial cells carcinogenicity oxidative stress reactive oxygen species gp120 Tat Nef matrix protein p17 reverse transcriptase mitochondria metastasis OXPHOS cancer Warburg effect cancer therapeutics myeloproliferative neoplasms signaling pathways JAK2 CALR MPL TPOR DUSP1 MAPK Snail prostate cancer migration and invasion patient survival biomarkers pBRD4 SET PP2A prognosis triple negative breast cancer resistance anti-receptor therapy trastuzumab PI3K mTOR TAK-228 epigenetic methylation acetylation non-coding RNA small-cell lung cancer triple-negative breast cancer pancreatic ductal adenocarcinoma glioblastoma metastatic melanoma advanced ovarian cancer hepatocellular carcinoma immune evasion immunotherapy immune checkpoint inhibitors oncogenic signaling pathway molecular targeted agents genome epigenome tumor immune microenvironment ovarian cancer adaptive immunity innate immunity complement system cancer immunology tumor microenvironment splicing pathway luminal breast cancer BET inhibitors |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910566473703321 |
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Cristóbal Ion
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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New Insights into Parvovirus Research
| New Insights into Parvovirus Research |
| Autore | Gallinella Giorgio |
| Pubbl/distr/stampa | MDPI - Multidisciplinary Digital Publishing Institute, 2020 |
| Descrizione fisica | 1 electronic resource (342 p.) |
| Soggetto non controllato |
antivirals
Bombyx mori bidensovirus Bocaparvovirus human bocavirus 1 equine parvovirus-hepatitis NS2 NS1 X-ray crystallography BIRC3 (cIAP-2) glycans children antibody interactions new viruses alpaca cidofovir rodent protoparvoviruses clinical trials structural biology DNA virus human bocavirus caspase-3 viral communities uncoating PLA2 phospholipase-A2 oncolytic virus immune therapy Parvoviridae viral ecology Cryo-EM AAV metagenomics phylogeny oncolytic viruses mite parvovirus evolution Carnivore protoparvovirus 1 adeno-associated virus telbivudine capsid stability virus homology modeling human airway epithelia sequence analysis acute gastroenteritis bisulfite PCR next-generation sequencing single stranded DNA virus overlapping promoters virus diversity prognosis oncolytic activity genome hydroxyurea Lepidoptera genome externalization antiviral compounds circulating angiogenic cells tumor microenvironment coumarin derivatives nuclear targeting densovirus receptor interactions cell cycle arrest transcription profile brincidofovir canine parvovirus endogenous viral elements inflammatory cardiomyopathy erythroid progenitor cells RNA-seq insect chapparvovirus RT-qPCR trafficking AAV2 agricultural pests Adeno-associated virus myocarditis diagnosis parvovirus feline panleukopenia virus chitin B19V transcription mapping flavonoids immunomodulation erythrovirus apoptosis adenoviral vector anti-cancer divalent cations protease genetics preclinical arthropod peritrophins biocontrol dilated cardiomyopathy insect parvovirus combination therapies intravenous immunoglobulin (IVIG) virus phylogeny evolution second generation parvovirus treatments commercial horse serum parvovirus B19 canine chapparvovirus CpG methylation RACE H-1PV viral metagenomics horses |
| ISBN | 3-03928-311-1 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910404088603321 |
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Gallinella Giorgio
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| MDPI - Multidisciplinary Digital Publishing Institute, 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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