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Clinical Studies, Big Data, and Artificial Intelligence in Nephrology and Transplantation
| Clinical Studies, Big Data, and Artificial Intelligence in Nephrology and Transplantation |
| Autore | Cheungpasitporn Wisit |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 electronic resource (374 p.) |
| Soggetto topico | Medicine |
| Soggetto non controllato |
tacrolimus
C/D ratio tacrolimus metabolism everolimus conversion kidney transplantation gut microbiome renal transplant recipient diarrhea immunosuppressive medication gut microbiota 16S rRNA sequencing butyrate-producing bacteria Proteobacteria torquetenovirus immunosuppression transplantation immunosuppressed host outcome renal transplantation Goodpasture syndrome anti-GBM disease epidemiology hospitalization outcomes acute kidney injury risk prediction artificial intelligence patent ductus arteriosus conservative management blood pressure eradication interferon-free regimen hepatitis C infection kidney transplant allograft steatosis lipopeliosis transplant numbers live donors public awareness Google TrendsTM machine learning big data nephrology chronic kidney disease NLR PLR RPGN predictive value hemodialysis withdrawal cellular crescent global sclerosis procurement kidney biopsy glomerulosclerosis minimally-invasive donor nephrectomy robot-assisted surgery laparoscopic surgery organ donation living kidney donation MeltDose® LCPT renal function liver transplantation metabolism erythropoietin fibroblast growth factor 23 death weekend effect in-hospital mortality comorbidity dialysis elderly klotho α-Klotho FGF-23 kidney donor Nephrology CKD-MBD CKD-Mineral and Bone Disorder deceased donor Eurotransplant Senior Program risk stratification intensive care kidney transplant recipients long-term outcomes graft failure cardiovascular mortality lifestyle inflammation vascular calcification bone mineral density dual-energy X-ray absorptiometry living donation repeated kidney transplantation graft survival prolonged ischaemic time patient survival pre-emptive transplantation metabolomics urine acute rejection allograft cystatin C hyperfiltration kidney injury molecule (KIM)-1 tubular damage genetic polymorphisms (cardiac) surgery inflammatory cytokines clinical studies chronic kidney disease (CKD) no known kidney disease (NKD) ICD-10 billing codes phenotyping electronic health record (EHR) estimated glomerular filtration rate (eGFR) machine learning (ML) generalized linear model network (GLMnet) random forest (RF) artificial neural network (ANN), clinical natural language processing (clinical NLP) discharge summaries laboratory values area under the receiver operating characteristic (AUROC) area under the precision-recall curve (AUCPR) fibrosis extracellular matrix collagen type VI living-donor kidney transplantation ethnic disparity |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557367503321 |
Cheungpasitporn Wisit
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Cytochromes P450: Drug Metabolism, Bioactivation and Biodiversity 2.0
| Cytochromes P450: Drug Metabolism, Bioactivation and Biodiversity 2.0 |
| Autore | Dansette Patrick M |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 electronic resource (286 p.) |
| Soggetto topico | Research & information: general |
| Soggetto non controllato |
Antibiotics
Bacillus biosynthetic gene clusters comparative analysis cytochrome P450 monooxygenase Mycobacterium P450 diversity percentage P450 profiling secondary metabolites NADPH-cytochrome P450 reductase (CPR) microsomal cytochrome P450 (CYP) Cytochrome b5 (CYB5) protein dynamics electron-transfer (ET) protein–protein interaction cytochromes P450 CYP3A4 active site access channels cavities boundaries minimal cost paths CYP139A1 genome data mining host metabolism Mycobacterium tuberculosis polyketides tuberculosis cryptococcus cryptococcus neoformans CYP51 fungal pathogens genome data-mining human pathogens CYP diversity analysis tremellomycetes trichosporon mechanism-based inhibitor crystal structure CYP4 genes genetic polymorphisms 20-HETE fatty acid arachidonic acid SNPs molecular functionality metabolism lamellar ichthyosis Bietti’s crystalline dystrophy cytochrome P450 isoform membrane protein protein-membrane interactions enzyme substrate specificity mutagenesis molecular dynamics simulation Sogatella furcifera sulfoxaflor transcriptome RNA interference CYP2C8 polymorphisms reactive oxygen species paclitaxel cytochrome P450 reductase electron transfer extracellular vesicles exosomes extrahepatic tissues plasma circulatory CYPs CYP450 drug metabolism precision Cardio-Oncology precision medicine systems medicine cytochromes P450 monooxygenases Cyanobacteria gene-cluster diversity percentage mathematical formula phylogenetic analysis Streptomyces cytochrome P450 monooxygenases terpenes P450 blooming non-ribosomal peptides cytochrome P450 monooxygenenases CYP128A1 Mycobacterium tuberculosis H37Rv molecular dynamic simulations azole drugs menaquinone |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | Cytochromes P450 |
| Record Nr. | UNINA-9910557761103321 |
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Dansette Patrick M
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Neurotransmitter-Related Molecular Modeling Studies
| Neurotransmitter-Related Molecular Modeling Studies |
| Autore | Nowaczyk Alicja |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 electronic resource (188 p.) |
| Soggetto topico |
Research & information: general
Chemistry |
| Soggetto non controllato |
white matter hyperintensities
dysautonomia genetic polymorphisms dementia levodopa renin-angiotensin system orthostatic hypotension reserpine-induced fibromyalgia model vortioxetine ropinirole serotonin and dopamine in fibromyalgia mouse dopamine acetylcholine glutamate BDNF serotonin neurotransmitters statins neurodegenerative diseases stroke depression androgenetic alopecia 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitors mixed dyslipidemia risk factors halogenated pyrazolines monoamine oxidase inhibitors kinetics reversibility molecular dynamics guanylate cyclase (GC) chronic heart failure (CHF) pulmonary arterial hypertension (PAH) tiagabine cardiac voltage-gated ion channels molecular modeling ECG study SGLT2i sodium-glucose cotransporter 2 inhibitors neuroprotection atheroprotection mTOR type 2 diabetes mellitus cognitive impairment inflammation oxidative stress antibiotics neurotoxicity adverse drug reaction neurotransmission 5-HT receptors gastrointestinal tract |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910580213903321 |
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Nowaczyk Alicja
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Pharmacogenomics and Personalized Medicine
| Pharmacogenomics and Personalized Medicine |
| Autore | Cecchin Erika |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 |
| Descrizione fisica | 1 electronic resource (208 p.) |
| Soggetto topico | Medicine |
| Soggetto non controllato |
CYP2C9
VKORC1 warfarin warfarin initiation phase of therapy INR pharmacogenetics study pharmacogenomics pharmacogenetics genotype phenotype alleles precision medicine pharmacotranscriptomics high-throughput analysis childhood acute lymphoblastic leukemia clopidogrel acenocoumarol CDSS implementation azathioprine inflammatory bowel disease glutathione-S transferase pharmacokinetics nucleoside analogs microRNAs gene expression drug resistance AML cisplatin nephrotoxicity kidney injury genetic polymorphisms pre-emptive panel breast cancer subtype miRNA pathway crosstalk network precision drugs ovarian cancer platinum resistance focal copy number alterations whole exome sequencing personalized medicine human genetics pharmacology |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557287703321 |
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Cecchin Erika
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Physiology, Biochemistry, and Pharmacology of Transporters for Organic Cations
| Physiology, Biochemistry, and Pharmacology of Transporters for Organic Cations |
| Autore | Ciarimboli Giuliano |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 electronic resource (248 p.) |
| Soggetto topico | Medicine |
| Soggetto non controllato |
transporters
endogenous metabolism functional subgroups SLC22 remote sensing and signaling drug transporters gut microbiome chronic kidney disease solute carrier 22 (SLC22) Remote Sensing and Signaling Theory interorgan communication organic anion transporter organic cation transporter SLC22A15 SLC22A16 SLC22A18 kidney Malpighian tubule TCGA human pathology atlas gene ontology organic cations transport kidneys regulation Nuclear receptor renal excretion bile acids organic cation transporters drug disposition genetic polymorphisms drug-induced kidney injury nephrotoxicity RA Tofacitinib Baricitinib MATE1 solute carrier (SLC) family OCT1 SLC22A1 species differences drugs pesticides cisplatin nephrotoxicity PPAR-alpha organic transporters serotonin transporter plasma membrane monoamine transporter ketamine isoflurane serotonin clearance antidepressant-like activity chronoamperometry tail suspension test forced swim test hepatotoxicity solute carrier pulmonary drug delivery SLC22A1-5 lung epithelium drug uptake β2-agonists chronic lung diseases anticholinergics trospium OCT MATE drug excretion drug transport |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557346203321 |
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Ciarimboli Giuliano
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Role of MicroRNA in Cancer Development and Treatment
| Role of MicroRNA in Cancer Development and Treatment |
| Autore | Pulliero Alessandra |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 electronic resource (280 p.) |
| Soggetto topico |
Medicine
Pharmacology |
| Soggetto non controllato |
breast cancer
miRNAs liquid biopsy angiogenesis biomarkers early diagnosis air pollution biomarker exposure human lung cancer miRNA carcinogenesis microRNA asbestos exposure oral squamous cell carcinoma diagnosis prognosis saliva neuroblastoma MYCN amplification metastases chemoresistance public health genomics genetic polymorphisms epigenetic modulations genetic and microbiome markers health technology assessment early disease prevention nonsmokers lung cancer environmental risk factors oncogenes mutations glioblastoma microRNAs cancer qPCR cancer stem cells plasticizers in vitro study PRISMA no-smokers lung cancer DNA adducts mesothelioma extracellular vesicles miR-625 fluoro-edenite asbestos malignant mesothelioma cancer prevention microbiota epigenetics environmental pollutants cutaneous tissues ozone exposure |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910576878603321 |
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Pulliero Alessandra
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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