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PPARs as Key Mediators of Metabolic and Inflammatory Regulation
| PPARs as Key Mediators of Metabolic and Inflammatory Regulation |
| Autore | Vázquez-Carrera Manuel |
| Pubbl/distr/stampa | MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 online resource (456 p.) |
| Soggetto topico |
Biochemistry
Biology, life sciences Research and information: general |
| Soggetto non controllato |
adipose tissue
AMPK amygdala atopic dermatitis bezafibrate brain browning cancer common carotid artery occlusion coregulator corticotropin releasing hormone coumarin crystal structure cytomegalovirus dairy animals depression diabetes DNA methylation docking doping control dual/pan agonist electroretinography ELISA energy homeostasis exercise fatty acid oxidation fatty acids fenofibrate fenofibric acid fibroblast growth factor 21 fluorescent ligand GDF15 gene transcription glucose GSK3787 GW0742 hepatic damage hepatic sex-biased gene expression histone modification HIV immunity immunohistochemistry infection inflammation insulin resistance kidney fibrosis ligand lipid droplets lipid metabolism lipidomics lipopolysaccharide (LPS) liver damage lung M. leprae M. tuberculosis metabolic alterations metabolic reprograming metabolic syndrome microglia micronutrients miRNA molecular docking mycobacteria n/a neural stem cells neurogenesis neuroinflammation neuropathology nitric oxide synthase non-alcoholic fatty liver disease (NAFLD) non-alcoholic steatohepatitis (NASH) nonalcoholic fatty liver disease (NAFLD) norepinephrine nuclear factors nuclear receptor nuclear receptors nucleus accumbens nutrigenomics obesity oleoylethanolamide P2Y2 receptor palmitoylethanolamide pattern-recognition receptors pemafibrate peroxisome peroxisome proliferator-activated receptor peroxisome proliferator-activated receptor alpha peroxisome proliferator-activated receptor gamma (PPARγ) peroxisome proliferator-activated receptors (PPAR) peroxisome-proliferator-activated receptor phagocytosis pharmacological targets PPAR PPAR gamma PPARg PPARs PPARα PPARα knockout PPARβ/δ PPARγ PPARγ ligand PPRE proliferation psoriasis pulmonary arterial hypertension pulmonary artery quercetin real-time PCR regulatory T cells resveratrol retinal ischemia screening sex dimorphism signaling pathway skeletal muscle subgenual prefrontal cortex substrate metabolism TGFβ toll-like receptor 4 type 2 diabetes mellitus vascular injury X-ray crystallography Zika β-oxidation |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910576873703321 |
Vázquez-Carrera Manuel
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| MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Refinements to Animal Models for Biomedical Research
| Refinements to Animal Models for Biomedical Research |
| Autore | Musk Gabrielle |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 online resource (234 p.) |
| Soggetto topico |
Biology, life sciences
Research and information: general |
| Soggetto non controllato |
3R principles
anaesthesia analgesia animal research animal testing behaviour biomedical research blood sample calves camel captive bolt castration cat Cavia porcellus cytokines disbudding dog facial expressions functional MRI gene transcription grimace scales grimace scores guinea pig health history of science horse humane euthanasia humane killing laboratory animal laboratory animals meloxicam mice mouse n/a nCounter neonate nociception nociceptive threshold pain pain assessment peri-operative piglet postoperative analgesia preclinical research rabbit rat rat anaesthesia refinement retrobulbar sheep sublingual submandibular survey transdermal fentanyl patch vocalisation well-being |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557128603321 |
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Musk Gabrielle
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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The Tight Junction and Its Proteins : More Than Just a Barrier
| The Tight Junction and Its Proteins : More Than Just a Barrier |
| Autore | Fromm Michael |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 |
| Descrizione fisica | 1 online resource (432 p.) |
| Soggetto topico | Medicine |
| Soggetto non controllato |
actomyosin
adherens junction adherens junctions aging AMP-activated protein kinase (AMPK) angubindin-1 angulin anhidrosis antibiotic-associated hemorrhagic colitis antibody antidiuretic hormone apical junctional complex apoptosis aquaporin arachnoid barrier atopic dermatitis atypical aPKCζ barrier formation barrier function biliary epithelial cells blood-biliary barrier blood-brain barrier blood-cerebrospinal fluid barrier brain barriers calcium permeability Campylobacter jejuni cancer caspase CaSR celiac disease cell growth cell polarity cell-cell contact cerebral cavernous malformation chemoresistance cholangiocellular carcinoma cholestasis chronic liver disease claudin Claudin claudin 1 claudin targeting claudin-1 claudin-12 Claudin-14 claudin-2 claudin-5 Claudin-7 claudins ClC-2 CLDN14 Clostridium perfringens enterotoxin Clostridium perfringens iota-toxin co-culture cochlear implantation collecting duct curcumin cytokines disease dorsal root ganglion drinking rate drug development drug discovery endometrial cancer endothelia endothelial barrier enterocyte enteropathogenic E. coli (EPEC) environmental sensors epidermal barrier epithelia epithelial barrier epithelial barrier dysfunction epithelial fluid transport epithelial sodium channel (ENaC), collecting duct cells epithelial to mesenchymal transition epithelium EspF fibrosis gene transcription gland dysfunction glia limitans hearing loss HELIX syndrome Hepatitis C Virus hepatocellular carcinoma human hydrogen peroxide hydrostatic pressure hypermagnesemia hypertrophy hypokalemia immune cells in silico inflammation inflammatory bowel disease interleukin 13 intestinal mucosa intestine ion channel ion reabsorption ion transport ischemia junctional adhesion molecule kidney kidney stones Klebsiella oxytoca lipolysis-stimulated lipoprotein receptor (LSR) liver lung MAGUK proteins MDCK C7 cells MEKK3 membrane proteins metastasis mice migration molecular dynamics monocytes mouse colon mucosal immunology mucus mutations Mz-ChA-1 cells nephropathy nerve injury NES neuropathic pain neurovascular unit NFκB NHE2 NISCH syndrome NLS occludin organ preservation osmolality osmoregulation paracellular paracellular barrier paracellular channels and barriers paracellular permeability paracellular sodium transport paracellular transport paracellular water transport pathogens PDZ domain permeability phosphatidylcholine phosphorylation polarity proliferation protein domain protein interactions protein structure proximal tubule quercetin reconstructed human epidermis repair retinal pigment epithelium retinopathy Rho RhoA ROCK sensor single molecule localization microscopy skin sorting nexin 9 (SNX9) STAT3 stem cell stimulated emission depletion structured illumination microscopy super-resolution microscopy thick ascending limb tight epithelium tight junction tight junction assembly tight junctions tight junctions (TJ) tissue barrier TNF transepithelial electrical resistance (TER) transplantation tricellular tight junction tricellular tight junctions tricellulin tumor tumor suppressor UBE2Z ubiquitin vestibular function viral entry WNK4 ZO-1 ZO-2 zonula occludens |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | Tight Junction and Its Proteins |
| Record Nr. | UNINA-9910557404603321 |
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Fromm Michael
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||
| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
The Tight Junction and Its Proteins: More Than Just a Barrier : More Than Just a Barrier
| The Tight Junction and Its Proteins: More Than Just a Barrier : More Than Just a Barrier |
| Autore | Fromm Michael |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 |
| Descrizione fisica | 1 online resource (412 p.) |
| Soggetto topico | Medicine |
| Soggetto non controllato |
actomyosin
adherens junction adherens junctions aging AMP-activated protein kinase (AMPK) angubindin-1 angulin anhidrosis antibiotic-associated hemorrhagic colitis antibody antidiuretic hormone apical junctional complex apoptosis aquaporin arachnoid barrier atopic dermatitis atypical aPKCζ barrier formation barrier function biliary epithelial cells blood-biliary barrier blood-brain barrier blood-cerebrospinal fluid barrier brain barriers calcium permeability Campylobacter jejuni cancer caspase CaSR celiac disease cell growth cell polarity cell-cell contact cerebral cavernous malformation chemoresistance cholangiocellular carcinoma cholestasis chronic liver disease claudin Claudin claudin 1 claudin targeting claudin-1 claudin-12 Claudin-14 claudin-2 claudin-5 Claudin-7 claudins ClC-2 CLDN14 Clostridium perfringens enterotoxin Clostridium perfringens iota-toxin co-culture cochlear implantation collecting duct curcumin cytokines disease dorsal root ganglion drinking rate drug development drug discovery endometrial cancer endothelia endothelial barrier enterocyte enteropathogenic E. coli (EPEC) environmental sensors epidermal barrier epithelia epithelial barrier epithelial barrier dysfunction epithelial fluid transport epithelial sodium channel (ENaC), collecting duct cells epithelial to mesenchymal transition epithelium EspF fibrosis gene transcription gland dysfunction glia limitans hearing loss HELIX syndrome Hepatitis C Virus hepatocellular carcinoma human hydrogen peroxide hydrostatic pressure hypermagnesemia hypertrophy hypokalemia immune cells in silico inflammation inflammatory bowel disease interleukin 13 intestinal mucosa intestine ion channel ion reabsorption ion transport ischemia junctional adhesion molecule kidney kidney stones Klebsiella oxytoca lipolysis-stimulated lipoprotein receptor (LSR) liver lung MAGUK proteins MDCK C7 cells MEKK3 membrane proteins metastasis mice migration molecular dynamics monocytes mouse colon mucosal immunology mucus mutations Mz-ChA-1 cells nephropathy nerve injury NES neuropathic pain neurovascular unit NFκB NHE2 NISCH syndrome NLS occludin organ preservation osmolality osmoregulation paracellular paracellular barrier paracellular channels and barriers paracellular permeability paracellular sodium transport paracellular transport paracellular water transport pathogens PDZ domain permeability phosphatidylcholine phosphorylation polarity proliferation protein domain protein interactions protein structure proximal tubule quercetin reconstructed human epidermis repair retinal pigment epithelium retinopathy Rho RhoA ROCK sensor single molecule localization microscopy skin sorting nexin 9 (SNX9) STAT3 stem cell stimulated emission depletion structured illumination microscopy super-resolution microscopy thick ascending limb tight epithelium tight junction tight junction assembly tight junctions tight junctions (TJ) tissue barrier TNF transepithelial electrical resistance (TER) transplantation tricellular tight junction tricellular tight junctions tricellulin tumor tumor suppressor UBE2Z ubiquitin vestibular function viral entry WNK4 ZO-1 ZO-2 zonula occludens |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | Tight Junction and Its Proteins |
| Record Nr. | UNINA-9910674057303321 |
|
Fromm Michael
|
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||