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Application of Bioinformatics in Cancers
| Application of Bioinformatics in Cancers |
| Autore | Brenner J. Chad |
| Pubbl/distr/stampa | MDPI - Multidisciplinary Digital Publishing Institute, 2019 |
| Descrizione fisica | 1 electronic resource (418 p.) |
| Soggetto non controllato |
cancer treatment
extreme learning independent prognostic power AID/APOBEC HP gene inactivation biomarkers biomarker discovery chemotherapy artificial intelligence epigenetics comorbidity score denoising autoencoders protein single-biomarkers gene signature extraction high-throughput analysis concatenated deep feature feature selection differential gene expression analysis colorectal cancer ovarian cancer multiple-biomarkers gefitinib cancer biomarkers classification cancer biomarker mutation hierarchical clustering analysis HNSCC cell-free DNA network analysis drug resistance hTERT variable selection KRAS mutation single-cell sequencing network target skin cutaneous melanoma telomeres Neoantigen Prediction datasets clinical/environmental factors StAR PD-L1 miRNA circulating tumor DNA (ctDNA) false discovery rate predictive model Computational Immunology brain metastases observed survival interval next generation sequencing brain machine learning cancer prognosis copy number aberration mutable motif steroidogenic enzymes tumor mortality tumor microenvironment somatic mutation transcriptional signatures omics profiles mitochondrial metabolism Bufadienolide-like chemicals cancer-related pathways intratumor heterogeneity estrogen locoregionally advanced RNA feature extraction and interpretation treatment de-escalation activation induced deaminase knockoffs R package copy number variation gene loss biomarkers cancer CRISPR overall survival histopathological imaging self-organizing map Network Analysis oral cancer biostatistics firehose Bioinformatics tool alternative splicing biomarkers diseases genes histopathological imaging features imaging TCGA decision support systems The Cancer Genome Atlas molecular subtypes molecular mechanism omics curative surgery network pharmacology methylation bioinformatics neurological disorders precision medicine cancer modeling miRNAs breast cancer detection functional analysis biomarker signature anti-cancer hormone sensitive cancers deep learning DNA sequence profile pancreatic cancer telomerase Monte Carlo mixture of normal distributions survival analysis tumor infiltrating lymphocytes curation pathophysiology GEO DataSets head and neck cancer gene expression analysis erlotinib meta-analysis traditional Chinese medicine breast cancer TCGA mining breast cancer prognosis microarray DNA interaction health strengthening herb cancer genomic instability |
| ISBN | 3-03921-789-5 |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910367743403321 |
Brenner J. Chad
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| MDPI - Multidisciplinary Digital Publishing Institute, 2019 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Bioactive Compounds from Marine-Derived Aspergillus, Penicillium, Talaromyces and Trichoderma Species
| Bioactive Compounds from Marine-Derived Aspergillus, Penicillium, Talaromyces and Trichoderma Species |
| Autore | Nicoletti Rosario |
| Pubbl/distr/stampa | MDPI - Multidisciplinary Digital Publishing Institute, 2019 |
| Descrizione fisica | 1 electronic resource (134 p.) |
| Soggetto non controllato |
antibacterial activity
Talaromyces purpurogenus lapatinib antibacterial hydroxypyrrolidine bis-indolyl benzenoids penitrem A cytotoxicities sesquiterpenoid secondary metabolites drug discovery sponge-associated fungus candidusin Penicillium sp. TJ403-1 coumarin gefitinib bioactive products Aspergillaceae indole-diterpenoids mangroves diterpenoid Penicillium raistrickii ECD calculations Talaromyces marine-derived fungi BK (Maxi-K) channel polyketides EGFR chromone aspetritone Aspergillus breviane spiroditerpenoid endophytic fungi cytotoxic cytotoxicity breast cancer mangrove endophytic fungus IDH1 inhibitory activity NMR data calculations antifungal activity Aspergillus candidus diastereomers TNF-? sterone Aspergillus clavatus HER2 thermo-change strategy |
| ISBN | 3-03897-981-3 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910346857703321 |
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Nicoletti Rosario
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| MDPI - Multidisciplinary Digital Publishing Institute, 2019 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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The Design, Synthesis, and Biological Evaluation of Compounds with Medicinal Value
| The Design, Synthesis, and Biological Evaluation of Compounds with Medicinal Value |
| Autore | Sinicropi Maria |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 electronic resource (218 p.) |
| Soggetto topico |
Research & information: general
Chemistry |
| Soggetto non controllato |
fluorinated pyrazole aldehydes
tyrosinase inhibition phosphodiesterase inhibition antibacterial activity molecular docking periodontitis SRP LDD gelcide cancer phytocomponents Tiospora cardifolia silica silver oxynitrate stability core-shell antibiofilm antimicrobial sesquiterpene inflammatory pathologies nutraceuticals triclosan surgical site infection suture abdominal surgery cost-analysis budget impact analysis spirooxindole 1,3-dipolar cycloaddition eco-friendly chemistry ROCS shape alignment lipophilicity anticancer activity sol-gel coating medical textiles antioxidant anti-inflammatory PEA derivative drug release imidazole antiproliferative antioxidant activities docking DPPH ABTS acetylcholinesterase xanthine oxidase pyrimidine-trione barbituric thiobarbituric urease inhibitors DFT N-benzylisatin-aryl hydrazones gefitinib A549 cell lines pomegranate Punica granatum L. pomegranate skin extract pomegranate fruit extract nutraceutical properties biological properties cladodes Opuntia antioxidants polyphenols SFE-CO2 rutin iso-quercitrin nicotiflorin narcissin |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557332803321 |
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Sinicropi Maria
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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