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Looking Forward To The Future of Heparin : : New Sources, Developments and Applications / / Giangiacomo Torri, Jawed Fareed
| Looking Forward To The Future of Heparin : : New Sources, Developments and Applications / / Giangiacomo Torri, Jawed Fareed |
| Autore | Torri Giangiacomo |
| Pubbl/distr/stampa | MDPI - Multidisciplinary Digital Publishing Institute, 2018 |
| Descrizione fisica | 1 electronic resource (282 p.) |
| Soggetto topico | Chemistry |
| Soggetto non controllato |
alginate
edema Heparin Red solid lipid nanoparticles Fe3O4·DA-BSA/HA dermatan sulfate sulfated alginate porcine heparin theranostics low-molecular-weight heparin Arixtra® biomaterials hepcidin ovarian cancer iron oxide nanoparticles heparin-induced thrombocytopenia bone morphogenetic protein (BMP) hyaluronic acid (HA) crude heparin platelets resistance sclerostin LMWH gremlin low molecular weight heparin (LMWH) low molecular weight glycosaminoglycans human plasma single crystal X-ray structure iron homeostasis noggin super paramagnetic iron oxide nanoparticles (SPION) manufacturing methods paclitaxel (PTX) brain injury bovine heparin inflammation qNMR antithrombin reference standard quantitative NMR enoxaparin danaparoid sodium NMR GDNF orthogonal multi-analytical methods ternary complex heparan sulphate serglycin bovine serum albumin (BSA) HSQC recombinant expression heparin heparin oligosaccharides functional assay BMP antagonists intestinal lymphatic absorption size exclusion chromatography heparin coating diagnosis bioreactor anemia proteoglycan heparin process PCA chemometric fluorescent probe pharmacopeia affinity chromatography component quantitative analysis Fondaparinux sodium perylene diimide dyes thrombin inhibition extended physicochemical characterization cisplatin glycosaminoglycans TGF-? chondroitin sulfate dalteparin sequence and compositional investigations molecular weight magnetic resonance imaging (MRI) industrial LC-MS iduronic acid conformation heparan sulfate growth and differentiation factor (GDF) assay subarachnoid hemorrhage |
| ISBN |
9783038429500
3038429503 |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910346841803321 |
Torri Giangiacomo
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| MDPI - Multidisciplinary Digital Publishing Institute, 2018 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Molecular Basis and Gene Therapies of Cystic Fibrosis
| Molecular Basis and Gene Therapies of Cystic Fibrosis |
| Autore | Engelhardt John |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 |
| Descrizione fisica | 1 online resource (210 p.) |
| Soggetto topico | Medicine |
| Soggetto non controllato |
airway basal cell
baculovirus biomarker CFTR CFTR gene CFTR modulators CFTR variants CFTR-related disorders common and new pathogenic variants cyclophosphamide cystic fibrosis Cystic fibrosis disease liability drug development enterotoxin gene cluster ethnic Russian population exosomes functional assay gene therapy genotype-guided therapy genotype-phenotype correlations gut-lung axis health policies health policy human nasal epithelial cells incidence insect cells interpretation lentivirus lung lung microbiome metagenomics microvesicles miRNA molecular diagnosis MRSA newborn screening next generation sequencing Next Generation Sequencing (NGS) organoids penetrance pre-clinical in vitro models primary cells proteostasis rAAV2/HBoV1 small molecules Staphylococcus aureus superantigen survival transcriptomics transient immunosuppression trypsinogen |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557392203321 |
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Engelhardt John
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Opioids and Their Receptors : Present and Emerging Concepts in Opioid Drug Discovery II
| Opioids and Their Receptors : Present and Emerging Concepts in Opioid Drug Discovery II |
| Autore | Spetea Mariana |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 online resource (260 p.) |
| Soggetto topico |
Chemistry
Research & information: general |
| Soggetto non controllato |
acetic acid-induced writhing test
allosteric modulation analgesia analgesic angiotensin receptors behavior beta-arrestin binding buprenorphine chemotype chloroquine cholestasis chronic pain colitis DAMGO delta opioid receptor deoxycholic acid epigenetics fluorescence cross-correlation spectroscopy (FCCS) free fatty acid receptors functional assay G protein-coupled receptor (GPCR) G-protein-biased agonist GPCR high-throughput screen hot-plate HS-731 human brain inverse agonist irreversible antagonist kappa opioid receptor agonist ligands lipids locomotor activity mice molecular docking molecular dynamics molecular dynamics simulations molecular pharmacology morphine dosing n/a N/OFQ nalbuphine neuropathic pain nociceptin nociceptin/orphanin FQ receptor non-competitive antagonist NOP receptor opioid opioid peptide opioid receptor opioid receptors peptide synthesis peripheral opioid agonist piperazine prodynorphin pruritis receptor binding studies rubiscolins scratching selectivity serotonin SR-17018 tail-clip TAT-HIV thiazole tolerance transcription β-amino acids δ opioid receptor µ-opioid analgesics µ-opioid receptor |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | Opioids and Their Receptors |
| Record Nr. | UNINA-9910576875203321 |
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Spetea Mariana
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Opioids and Their Receptors : Present and Emerging Concepts in Opioid Drug Discovery
| Opioids and Their Receptors : Present and Emerging Concepts in Opioid Drug Discovery |
| Autore | Spetea Mariana |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 |
| Descrizione fisica | 1 online resource (358 p.) |
| Soggetto topico | Medicine |
| Soggetto non controllato |
(−)-N-phenethylnorhydromorphone analogs
[35S]GTPgammaS assay [Dmt1]DALDA 14-methoxycodeine-6-O-sulfate 1H-NMR experiments 6β-naltrexol abuse agonist allodynia analgesia analgesics antagonist arrestin recruitment beta-arrestin bias factor biased agonism biased agonist biased agonists biased ligands biased signaling bifunctional ligands binding binding affinity BNTX buprenorphine chronic constriction injury (CCI) codeine codeine-6-O-sulfate DADLE DALDA DAMGO delta opioid receptor dependence design and synthesis dihydrocodeine diphenethylamines docking dysbiosis fentanyl forskolin-induced cAMP accumulation assays functional assay G-protein bias heteromer hyperalgesia interaction fingerprints internalization inverse agonist ischemia kappa opioid receptor KGOP01 Leu-enkephalin loperamide lysosomes macrocyclic tetrapeptide mechanism elucidation misuse mitragynine molecular docking molecular dynamics molecular modeling & MOR and DOR agonists morphinan morphine mu opioid receptor mu receptor multifunctional ligands n/a naltrexone neonatal opioid withdrawal syndrome neurokinin-1 receptor neutral antagonist NTI derivative opioid opioid drugs opioid liabilities opioid peptide opioid peptides opioid peptides and peptidomimetics opioid receptors opioid side effects opioids over-the-counter drugs pain therapy partial agonism partial agonist peptide synthesis peripheral analgesic tolerance peripheral antinociception peripheral µ-opioid receptors pharmacology plasma stability potassium channels primary hippocampal culture PZM21 racemic synthesis of β2-amino acids receptor binding studies receptor model respiration respiratory depression selectivity simulation SR-17018 structure-activity relationships sulfonamide TAPP tolerance writhing test zerumbone β-arrestin recruitment assays β2-amino acids β2-Homo-amino acids δ opioid receptor δ opioid receptor antagonist μ opioid receptor µ opioid receptor µ-opioid receptor |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | Opioids and Their Receptors |
| Record Nr. | UNINA-9910557108003321 |
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Spetea Mariana
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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