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Application of Bioinformatics in Cancers
| Application of Bioinformatics in Cancers |
| Autore | Brenner J. Chad |
| Pubbl/distr/stampa | MDPI - Multidisciplinary Digital Publishing Institute, 2019 |
| Descrizione fisica | 1 online resource (418 p.) |
| Soggetto topico | Biotechnology |
| Soggetto non controllato |
activation induced deaminase
AID/APOBEC alternative splicing anti-cancer artificial intelligence bioinformatics Bioinformatics tool biomarker discovery biomarker signature biomarkers biostatistics brain brain metastases breast cancer breast cancer detection breast cancer prognosis Bufadienolide-like chemicals cancer cancer biomarker cancer biomarkers cancer CRISPR cancer modeling cancer prognosis cancer treatment cancer-related pathways cell-free DNA chemotherapy circulating tumor DNA (ctDNA) classification clinical/environmental factors colorectal cancer comorbidity score Computational Immunology concatenated deep feature copy number aberration copy number variation curation curative surgery datasets decision support systems deep learning denoising autoencoders differential gene expression analysis diseases genes DNA DNA sequence profile drug resistance epigenetics erlotinib estrogen extreme learning false discovery rate feature extraction and interpretation feature selection firehose functional analysis gefitinib gene expression analysis gene inactivation biomarkers gene loss biomarkers gene signature extraction genomic instability GEO DataSets head and neck cancer health strengthening herb hierarchical clustering analysis high-throughput analysis histopathological imaging histopathological imaging features HNSCC hormone sensitive cancers HP hTERT imaging independent prognostic power interaction intratumor heterogeneity knockoffs KRAS mutation locoregionally advanced machine learning meta-analysis methylation microarray miRNA miRNAs mitochondrial metabolism mixture of normal distributions molecular mechanism molecular subtypes Monte Carlo mortality multiple-biomarkers mutable motif mutation Neoantigen Prediction network analysis Network Analysis network pharmacology network target neurological disorders next generation sequencing observed survival interval omics omics profiles oral cancer ovarian cancer overall survival pancreatic cancer pathophysiology PD-L1 precision medicine predictive model protein R package RNA self-organizing map single-biomarkers single-cell sequencing skin cutaneous melanoma somatic mutation StAR steroidogenic enzymes survival analysis TCGA TCGA mining telomerase telomeres The Cancer Genome Atlas traditional Chinese medicine transcriptional signatures treatment de-escalation tumor tumor infiltrating lymphocytes tumor microenvironment variable selection |
| ISBN | 3-03921-789-5 |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910367743403321 |
Brenner J. Chad
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| MDPI - Multidisciplinary Digital Publishing Institute, 2019 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Functionally Relevant Macromolecular Interactions of Disordered Proteins
| Functionally Relevant Macromolecular Interactions of Disordered Proteins |
| Autore | Simon Istvan |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 |
| Descrizione fisica | 1 online resource (520 p.) |
| Soggetto topico |
Biology, life sciences
Research and information: general |
| Soggetto non controllato |
aggregation
CABS model co-evolution coarse-grained conformational plasticity copper binding correlated mutations decision tree based artificial neural network dehydron differentially regulated genes disorder-to-order regions disordered protein disordered protein platform DNA conformational landscape DNA-protein interactions drug discovery drugs dual threshold eIF4E epiproteome evolution evolutionary couplings extracellular FG-Nups fluorescence anisotropy folding functional analysis gene ontology analysis histone lysine methyltransferase homodimer HOTAIR hydration hydrogen bond immune inter-subunit interaction interaction surface intrinsic disorder intrinsic disorder prediction intrinsically disorder proteins intrinsically disordered intrinsically disordered protein intrinsically disordered proteins intrinsically disordered proteins (IDPs) intrinsically disordered region ion pair leukemia lncRNA MC simulations MEG3 membrane-less organelle meta strategy Microarray MLL proteins MLL4 molecular machines molecular recognition feature molten globule mutual synergistic folding N-terminal prion protein neurodegenerative disease neurodegenerative diseases Nuclear pore complex oligomer p300 HAT acetylation p53 phosphorylation physiological homeostasis plant virus post-translational modification post-translational modifications potyvirus prion disease mutations protein protein aggregation protein conformation protein hydrodynamics protein intrinsic disorder protein stability protein structure protein thermostability protein-protein interaction protein-RNA interactions residue co-variation residue contact network ribosomal protein RIN4 RNA binding RNA sequencing salt bridges secretion sequential DNA bending significance voting smFRET solvent-accessible surface area Sox2 sequential DNA loading spectroscopy stabilization center statistical force fields stress response structural disorder structural domain Tau fibrillation temperature response transcription factor dosage transcription factors transcriptome unstructured proteins VPg wide-line 1H NMR |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557509403321 |
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Simon Istvan
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Physiological Responses to Abiotic and Biotic Stress in Forest Trees / Andrea Polle, Heinz Rennenberg
| Physiological Responses to Abiotic and Biotic Stress in Forest Trees / Andrea Polle, Heinz Rennenberg |
| Autore | Polle Andrea |
| Pubbl/distr/stampa | MDPI - Multidisciplinary Digital Publishing Institute, 2019 |
| Descrizione fisica | 1 electronic resource (294 p.) |
| Soggetto topico | History of engineering and technology |
| Soggetto non controllato |
pure stands
ion relation Heterobasidion annosum salicylic acid antioxidant enzymes antioxidant activity Luquasorb intrinsic water-use efficiency Greece Pinus koraiensis Sieb. et Zucc ion homeostasis photosynthesis Pinus massoniana Stockosorb water relations Norway spruce rubber tree hydrophilic polymers drought stress ion relationships Carpinus betulus tree rings N nutrition disturbance Populus simonii Carr. (poplar) infection subcellular localization basal area increment mixed stands photosynthetic responses Aleppo pine water potential elevation gradient living cell physiological response antioxidant enzyme activity ion contents signal network expression soil N GA-signaling pathway differentially expressed genes Ca2+ signal climate ecophysiology Robinia pseudoacacia L. Heterobasidion parviporum mid-term plant tolerance canopy conductance DELLA tapping panel dryness osmotic adjustment substances abiotic stress wood formation malondialdehyde salinity treatments organic osmolytes bamboo forest non-structural carbohydrate Abies alba Mill tree salt stress Populus euphratica proline nutrition Carpinus turczaninowii plasma membrane Ca2+ channels gene regulation pathogen TCP forest type functional analysis Fraxinus mandshurica Rupr long-term drought defense response cold stress silicon fertilization gas exchange Fagus sylvatica L. glutaredoxin water availability 24-epiBL application Konjac glucomannan leaf properties reactive oxygen species sap flow ?13C salinity morphological indices chloroplast ultrastructure Moso Bamboo (Phyllostachys edulis) drought soluble sugar molecular cloning starch growth |
| ISBN |
9783039215157
3039215159 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910367755303321 |
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Polle Andrea
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| MDPI - Multidisciplinary Digital Publishing Institute, 2019 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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The Retina in Health and Disease
| The Retina in Health and Disease |
| Autore | Ptito Maurice |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 online resource (465 p.) |
| Soggetto topico |
Medicine and Nursing
Neurosciences |
| Soggetto non controllato |
3,5-DHBA
Ac2-26 African-American age-related macular degeneration AII amacrine cell altricial bird species Alzheimer's disease AMD amyloid angiogenesis angiography antioxidants apoptosis arterioles astrocytes ATP atypical cannabinoid receptors autophagy axon betulinic acid bioenergetics biomarker black catalase CD4+CD25+ cellular senescence Charles Bonnet syndrome clinical trials cognitive decline complement cascade complication development diabetes diabetes mellitus diabetic retinopathy dLGN Drp1 early detection eccentricity EEG electron microscopy electroretinography endoplasmic reticulum epidermal growth factor exendin-4 experimental models eye eye inflammation fingolimod FPR receptor functional analysis gap junction germ-free mice GFAP glucagon-like peptide-1 GPR81 growth cone GRP78 gut microbiome gut-retina axis HCAR1 HDAC high-fat diet histone deacetylase hyperglycemia hypoxia immunodeficient RCS rat immunohistochemistry inflammation inflammatory mediators iPSC iPSC-RPE ischemia-reperfusion injury kallikrein-kinin system kinin receptors lactate LED screen light damage lipopolysaccharide macroglia mesenchymal stem cells metabolism microglia microglia morphotype microvascular microvascular complications and dysfunction mitochondria monkeys motor protein Müller cells multiple sclerosis myosin 1C n/a natural bioactive extracts neurod neurodegeneration neuroprotection neurovascular unit Notch ON/OFF asymmetry optic nerve crush optic neuritis optical coherence tomography optical filter osteopontin outer segments oxidative stress parvalbumin photoreceptor photoreceptors precocial bird species progenitor cell programmed cell death Prox1 reactive oxygen species regeneration remodeling respiration resting state retina retinal degeneration retinal degenerative diseases retinal detachment retinal fluorescence imaging retinal ganglion cells retinal glial cell retinal inflammation retinal light injury retinal microglia retinal pigment epithelium retinal protection retinal transplantation retinal vessels retinogenesis retinopathy rhodopsin RNA sequencing senescence-associated galactosidase activity signal transducer and activator of transcription 3 spinal cord injury stem cell therapy stress response systemic disease trichostatin A (TSA) typical cannabinoid receptors ultrathin parylene unfolded protein response vascular endothelial growth factor (VEGF) vascularization visual function visual hallucination visual system zebrafish |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557336603321 |
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Ptito Maurice
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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