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Cancer Nanomedicine
| Cancer Nanomedicine |
| Autore | Hoskins Clare |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 |
| Descrizione fisica | 1 electronic resource (510 p.) |
| Soggetto topico | Technology: general issues |
| Soggetto non controllato |
antibody drug conjugate (ADC)
PD-L1 tumor spheroid disruption immune modulation doxorubicin graphene oxide adsorption cathepsin D cathepsin L anti-metastatic enzyme cancer therapy nanoparticles targeted delivery system siRNA osteopontin mammary carcinoma mesenchymal stem cells (MSCs) TAT peptide PLGA paclitaxel nano-engineered MSCs orthotopic lung tumor model intracranial glioma immunotherapy CPMV viral nanoparticles in situ vaccine albumin nanoparticles microbubble ultrasound theranostics hepatocellular carcinoma VX2 tumor intra-arterial chemotherapy lung cancer nanomedicine clinical status cancer therapy breast cancer cell signaling active targeting passive targeting EPR effect oncogenes nanoparticle drug delivery ligand tumor targeting biodistribution Mesoporous silica nanoparticle drug delivery system target treatment lanthanide metal hyaluronic acid hyaluronidase drug combination everolimus dual-targeting magnetic nanoparticles monoclonal antibodies nanostructured lipid carrier platelet membrane biomimicry plasmonic photothermal therapy gold nanorods surgery bleeding dogs cats stimuli-responsive DOX SN38 CSCs single-walled carbon nanotubes chirality separation NASH drug-gene delivery near IR hyperspectral imaging plasmonics copper VEGF glioblastoma differentiated neuroblastoma peptidomimetics real-time quantitative polymerase chain reaction (qPCR) actin combinatorial therapy anticancer and antibacterial activity temoporfin drug-in-cyclodextrin-in-liposome hybrid nanoparticles multicellular tumor spheroids cyclodextrins photodynamic therapy article yet reasonably common within the subject discipline antitumor strategy biomimetic core–shell nanoparticles NK cell-derived exosomes folate receptor albumin nanoparticle microfluidic cabazitaxel polydopamine nanoparticles size cytotoxicity iron affinity FA-DABA-SMA self-assembly oncogenic proteins intracellular disruption folic receptor alpha pancreatic cancer parvifloron D albumin erlotinib photodynamic therapy lipid nanoparticles tumor vectorization verteporfin ovarian carcinomatosis spheroids integrin RGD peptide cancer diagnosis radiotherapy hyperthermia therapy biomimetic nanocarrier membrane-wrapped cancer targeted delivery photothermal therapy imaging cancer nanomedicine tumor microenvironment nano–bio interactions clinical translation magnetic nanowires magnetic hyperthermia magnetic actuation magnetic drug targeting titanate nanotubes gold nanoparticles vectorization colloidal stability docetaxel prostate cancer mangiferin anti-topoisomerase activity extracellular vesicles exosomes chemico-physical functionalization loading translational medicine nanotechnology: bioengineering anacardic acid mitoxantrone targeted drug delivery liposomes melanoma apoptosis ascorbic acid angiogenesis epithelial-to-mesenchymal transition hypoxia immunosuppression metabolism nanotherapeutics tumour microenvironment DNA origami liposome remote loading acute toxicity organoids magnetic silica-coated iron oxide nanochains photothermal treatment hyperthermia collagen cellular microenvironment lymphadenectomy magnetometer sentinel lymph node dissection SPION superparamagnetic iron oxide nanoparticles Vδ2 T cells zoledronic acid polymeric nanoconstruct anti-tumor immunity colorectal carcinoma β-cyclodextrin nanosponges BALB-neuT mice brain tumours glioma blood brain barrier polymeric nanoparticles PEGylation dioleoylphosphatidylethanolamine poly(hydroxyethyl acrylate-co-allyl methyl sulfide) copolymer folate oxidation-sensitive release cellular interaction in vitro anti-cancer activity triple negative breast cancer organotin mesoporous silica nanoparticles MDA-MB-231 theranostic nanomaterials nanobiotechnology molecular imaging nanosystems nanomicelles ovarian cancer tumour targeting chemotherapeutics riboflavin vitamin B2 nanomedicines secondary structure mixed micelle pH responsive targeted therapy anti-cancer shear stress flow in vitro therapeutics diagnostics Immunotherapy |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557114703321 |
Hoskins Clare
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Drug Delivery of siRNA Therapeutics
| Drug Delivery of siRNA Therapeutics |
| Autore | Lamberti Gaetano |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 |
| Descrizione fisica | 1 electronic resource (288 p.) |
| Soggetto topico | Medicine |
| Soggetto non controllato |
oligonucleotide delivery
light-activated release intracellular release liposome indocyanine green drug co-delivery methotrexate siRNA antitumor effect mixed micelles targeted delivery system cationic liposome folate folate receptor cationic cholesterol derivative siRNA delivery gene knockdown tumor-targeting VEGFA VEGFR1 endoglin peptide angiogenesis gene silencing migration proliferation endothelial cells RNAi therapeutics amphiphilic dendrons PAMAM dendrimers self-assembling nanovectors covalent dendrimers NABDs liposomes clinical trials drug delivery nanoparticle carbonate apatite ERBB2 AKT breast cancer ovarian cancer polymer lipid delivery poly(ethylene) imine PEI RNA tyrosine-modification tumor xenograft magnetic nanoparticle iron oxide BCL2 BIRC5/survivin oral cancer aptamers cancer nanoparticles STAT6 polyaspartamide pegylation polyamine polyplexes asthma |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557498903321 |
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Lamberti Gaetano
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Foods of Plant Origin
| Foods of Plant Origin |
| Autore | Netzel Michael |
| Pubbl/distr/stampa | MDPI - Multidisciplinary Digital Publishing Institute, 2020 |
| Descrizione fisica | 1 electronic resource (204 p.) |
| Soggetto non controllato |
minerals
Allium sativum L. vitamin A intake value-added product phytochemicals antioxidant activity FAO (Food and Agriculture Organization) stable isotope dilution assay antioxidant capacity volatile compounds stir-frying thioesters Chenopodium quinoa sinigrin beta-carotene EFSA (European Food Safety Authority) indigenous food boiling subtropical fruits processing organosulfur compounds mineral availability nutrients orange fleshed sweet potato kaempferol composition glycaemic index estimation Brassica vegetables retention vitamin A postharvest quality underutilized crop health antimicrobial activity porridge Brassica microwave vacuum drying instant controlled pressure drop vitamins tropical fruits bioactive compounds UHPLC-QqQ-MS/MS DRIs/DRVs (Dietary Reference Intakes/Dietary Reference Values) and AI (Adequate Intake) food preservation polyphenols conductive hydro-drying sulforaphane Australian grown garlic Solanum tuberosum L. gluten-free pasta bakery products LC-MS/MS digestibility skimmed milk gari feijoa fruit Terminalia ferdinandiana HPLC-DAD-ESI-MS/MS protein quality functional properties folate photo technology Kakadu plum dietary fibre Capsicum annuum L. fibre thioacetals esters antioxidants polyunsaturated fatty acids vegetables steaming preservation Artocarpus altilis ‘Ma’afala’ Acca sellowiana plant food freeze-drying postharvest processing propionate proximate composition iberin shelf life indigenous crop cultivar starch durian Cassava |
| ISBN | 3-03928-567-X |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910404091703321 |
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Netzel Michael
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| MDPI - Multidisciplinary Digital Publishing Institute, 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Nutrition During Pregnancy and Lactation: Implications for Maternal and Infant Health
| Nutrition During Pregnancy and Lactation: Implications for Maternal and Infant Health |
| Autore | Redman Leanne M |
| Pubbl/distr/stampa | MDPI - Multidisciplinary Digital Publishing Institute, 2020 |
| Descrizione fisica | 1 electronic resource (238 p.) |
| Soggetto non controllato |
education
6?-sialyllactose milk composition growth chart overweight and obesity body composition pregnant women prenatal intervention thermal control slow digesting carbohydrates postpartum vitamin B12 micronutrients passive immunization antibodies physiological body-weight loss obesity proteolysis energy infant formula adolescents pregnancy gestational weight gain intervention randomized clinical trial food photography metabolic rate infancy micronutrient deficiency restraint folate nutrition lactation basal maintenance expenditure milk oligosaccharides maternal nutrition disinhibition weight retention DNA sequencing neuroplasticity generalized linear models metabolic flexibility non-alcoholic fatty liver disease prematurity full breastfeeding food cravings transcriptome maternal diet quality Healthy Eating Index human milk gestational weight gain energy expenditure lifestyle intervention RDA immunological properties mindful eating insulin-resistant pregnancy nutritional intervention DNA methylation neurobiology total sugars fetal growth overweight fetal development energy intake hippocampus race maternal obesity early programming uncontrolled and emotional eating breast milk health hepatic lipogenesis eating behavior physical activity Pregnancy meal replacements premature delivery sialic acid diet quality cognitive development iron growth breastfeeding |
| ISBN | 3-03928-055-4 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | Nutrition During Pregnancy and Lactation |
| Record Nr. | UNINA-9910372786603321 |
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Redman Leanne M
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| MDPI - Multidisciplinary Digital Publishing Institute, 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Recent Developments on Protein–Ligand Interactions : From Structure, Function to Applications
| Recent Developments on Protein–Ligand Interactions : From Structure, Function to Applications |
| Autore | de Brevern Alexandre G |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 electronic resource (282 p.) |
| Soggetto topico |
Research & information: general
Biology, life sciences Biochemistry |
| Soggetto non controllato |
pimaricin thioesterase
protein-substrate interaction macrocyclization molecular dynamics (MD) simulation pre-reaction state folate folate receptor peptide conjugation click reaction biolayer interferometry acetylcholinesterase resistance organophosphorus pesticides molecular modeling lepidopterous insects conserved patterns similarity 3D-patterns epigenetics protein-RNA interaction RRM domain inhibitor NMR fragment-based screening TDP-43 galectin-1 gulopyranosides fluorescence polarization benzamide selective phospholipase C gamma 1 SLP76 virtual screening pharmacophore mapping molecular docking molecular dynamics caspase inhibition protein-ligand binding free energy Monte Carlo sampling docking and scoring molecular conformational sampling procollagen C-proteinase enhancer-1 glycosaminoglycans computational analysis of protein-glycosaminoglycan interactions calcium ions fragment-based docking protein–ligand analysis drug discovery and design structure–activity relationships bioremediation High Energy Molecules HMX protein design nitroreductase flavoprotein substrate specificity pharmacophore secretoglobin odorant-binding protein chemical communication pheromone N-phenyl-1-naphthylamine in silico docking protein–ligand interactions 2D interaction maps ligand-binding assays protein-ligand complexes dataset clustering structural alignment refinement PD-1/PD-L1 immune checkpoint inhibitors biphenyl-conjugated bromotyrosine amino acid conjugation amino-X in silico simulation IC50 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti |
Recent Developments on Protein–Ligand Interactions
Recent Developments on ProteinâLigand Interactions |
| Record Nr. | UNINA-9910566462703321 |
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de Brevern Alexandre G
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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The Role of Nutrition in Cardiometabolic Health: Experimental, Clinical, and Community-Based Evidence
| The Role of Nutrition in Cardiometabolic Health: Experimental, Clinical, and Community-Based Evidence |
| Autore | Mahmoud Abeer M |
| Pubbl/distr/stampa | Basel, : MDPI Books, 2022 |
| Descrizione fisica | 1 electronic resource (194 p.) |
| Soggetto topico | Medicine |
| Soggetto non controllato |
vitamin D
obesity microvascular bariatric surgery weight loss nitric oxide cardiac remodeling cardiac dysfunction echocardiogram obese rats high-fat high-sugar diet vascular stiffness blood pressure whey protein isolate older adults dietary factor cardiovascular disease umbrella review low-carbohydrate diet hypocaloric isocaloric women health conduit artery microvasculature cardiovascular risks primary prevention homocysteine folate vitamin B12 vascular dysfunction hepatocyte TGR5 glucose regulation homocysteine and vascular disease H3K27me3 epigenetics atherosclerosis MRI (magnetic resonance imaging) liver metabolic regulation laparoscopic sleeve gastrectomy micronutrients deficiency body mass index cardiotonic steroids left ventricular mass marinobufagenin dietary salt intake young adults |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | Role of Nutrition in Cardiometabolic Health |
| Record Nr. | UNINA-9910674389803321 |
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Mahmoud Abeer M
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| Basel, : MDPI Books, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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The Role of PPARs in Disease
| The Role of PPARs in Disease |
| Autore | Wagner Nicole |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 electronic resource (274 p.) |
| Soggetto topico |
Medicine
Physiology |
| Soggetto non controllato |
peroxisome-proliferator activated receptors
tumor angiogenesis tumor progression metastasis formation endothelial cells RNA sequencing PPARs toxicology pharmacology ligand vascular coronary artery lipidomics eicosanoids inflammation CYP450 peroxisome proliferator-activated receptor angiogenesis proliferation metastasis immortality resistance to cell death growth suppressors immune system cellular metabolism PPAR nuclear receptors addiction alcohol nicotine opioids psychostimulants animal models human studies Alzheimer’s risk factors PPARα lipids fatty acids modulators cognition sex therapy hypertrophic adipocytes PPARG isoforms PPARG splicing dominant-negative isoform in vitro adipocytes adipogenesis hypertrophic obesity insulin-resistance peroxisome proliferator-activated receptors (PPARs) synthetic agonists non-alcoholic fatty liver disease (NAFLD) non-alcoholic steatohepatitis (NASH) fibrosis Sirtuin1 peroxisome proliferator-activated receptor-γ coactivator-1α peroxisome proliferator activated receptors obesity metabolic syndrome vitamin B12 folate fetal programming inherited metabolic disorders PGC-1α, disease kidney cancer AKI CKD nephron PKD cilia cystogenesis ligands Alzheimer’s disease (AD) |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910566482503321 |
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Wagner Nicole
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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