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Antiviral Agents
| Antiviral Agents |
| Autore | Adamson Catherine |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 |
| Descrizione fisica | 1 online resource (386 p.) |
| Soggetto topico |
Biology, life sciences
Research and information: general |
| Soggetto non controllato |
acteoside
acute/latent infection acyclovir adoptive cell therapy antipsychotic drug antiviral antiviral activity antiviral agent antiviral agents antiviral drug antiviral effect antiviral inhibitor antiviral strategies branched peptides brevilin A Burkitt lymphoma cells C-FRA cathelicidins central nervous system chemical footprinting Clerodendrum trichotomum clozapine combination antiretroviral therapy (cART) congenital infection coxsackievirus B4 CRISPR/Cas cytomegalovirus defensins dried blood spots dried plasma spots drug discovery endocytosis enteroviruses epigallocatechin gallate Epstein-Barr virus Ethiopia flavivirus flavonoids fluoxetine furin inhibitor ganciclovir genistein ginsenoside Rg1 glycosphingolipids HCMV vaccine hemagglutinin (HA) heparan sulfate hepatitis C virus hepcidins herpes B virus herpes viruses herpesvirus HIV human antimicrobial peptides human immunodeficiency virus ie-1 gene IE1 IE2 immediate-early influenza A virus influenza A virus (IAV) Japanese encephalitis virus latent infection lectin lipid biosynthesis LUMS1 lytic gene expression macacine herpesvirus-1 measles virus microvirin mutations n/a neural stem cells NF-κB signaling pathway non-immunogenic NS5 nucleic acid-based therapeutic approach nucleoside analogues oleanane-type derivatives orthohantavirus pediatrics PEI persistent infection phenyl-benzotriazoles Plantago asiatica polyethylenimine Porcine circovirus type 2 porcine reproductive and respiratory syndrome virus pre-treatment drug resistance precursor membrane protein pro-inflammatory factor prodrugs protein drugs ProTides PRRSV quantitative real-time PCR replication resistance Rev response element ribozyme RNA interference RNA-dependent RNA polymerase RSV sesquiterpene lactone SHAPE small molecule sphingolipids Surveyor nuclease mutation detection assay TALEN therapeutic effects therapeutic strategies transferrins treatments tropism viral entry virion internalization virus attachment virus entry inhibitors viruses Zika virus |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557448703321 |
Adamson Catherine
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Developmental Exposure to Environmental Contaminants
| Developmental Exposure to Environmental Contaminants |
| Autore | Stietz Kimberly Keil |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 electronic resource (256 p.) |
| Soggetto topico |
Medicine
Medical toxicology |
| Soggetto non controllato |
arsenic
synaptic transmission long-term potentiation hippocampus development lower urinary tract bladder inflammation POPs developmental basis of adult disease multigenerational toxicants bronchopulmonary dysplasia therapeutics lung development selective serotonin reuptake inhibitor perinatal mortality neonatal morbidity fluoxetine sertraline endocrine-disrupting chemicals (EDC) Aroclor 1221 (A1221) PCBs vinclozolin social behavior sex differences transgenerational epigenetic endocrine-disrupting chemical (EDC) polychlorinated biphenyl (PCB) mating behavior paced mating ultrasonic vocalization (USV) estradiol triclosan triclocarbon detergents 4-nonylphenol Danio rerio zebrafish environmental toxicity aquatic environment ground water chemicals lower urinary tract dysfunction lower urinary tract symptoms BPH prostate axonal growth developmental neurotoxicity neuronal morphogenesis PBDE reactive oxygen species thyroid hormone pesticides prebiotic intestinal dysbiosis perigestational dysmetabolism risk factor behavior chemical screening literature comparison developmental toxicity negative control positive control rapid testing PFAS PFAS mixtures epigenetics microglia valproic acid primary motor cortex |
| ISBN | 3-0365-5885-3 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910639989003321 |
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Stietz Kimberly Keil
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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In Silico Strategies for Prospective Drug Repositionings
| In Silico Strategies for Prospective Drug Repositionings |
| Autore | Udrescu Lucreția |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 electronic resource (288 p.) |
| Soggetto topico |
Medicine
Pharmaceutical industries |
| Soggetto non controllato |
COVID-19
drug repurposing topological data analysis persistent Betti function SARS-CoV-2 network-based pharmacology combination therapy nucleoside GS-441524 fluoxetine synergy antidepressant natural compounds QSAR molecular docking drug repositioning UK Biobank vaccine LC-2/ad cell line drug discovery docking MM-GBSA calculation molecular dynamics cytotoxicity assay GWAS multiple sclerosis oxidative stress repurposing ADME-Tox bioinformatics complex network analysis modularity clustering ATC code hidradenitis suppurativa acne inversa transcriptome proteome comorbid disorder biomarker signaling pathway druggable gene drug-repositioning MEK inhibitor MM/GBSA Glide docking MD simulation MM/PBSA single-cell RNA sequencing pulmonary fibrosis biological networks p38α MAPK allosteric inhibitors in silico screening computer-aided drug discovery network analysis psychiatric disorders medications psychiatry mental disorders toxoplasmosis Toxoplasma gondii in vitro screening drug targets drug-disease interaction target-disease interaction DPP4 inhibitors lipid rafts |
| ISBN | 3-0365-6133-1 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910639987703321 |
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Udrescu Lucreția
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Pharmaceutical Residues in the Environment
| Pharmaceutical Residues in the Environment |
| Autore | Kumirska Jolanta |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 |
| Descrizione fisica | 1 online resource (292 p.) |
| Soggetto topico |
Environmental economics
Research and information: general |
| Soggetto non controllato |
5-fluorouracil
activated sludge (AS) antibiotic resistance antibiotic resistance genes antibiotic resistance genes (ARGs) antibiotic-resistant bacteria (ARB) antibiotics antibiotics, antibiotic resistance aquatic compartments bacterial community BDD anode chromatographic methods constructed wetlands constructed wetlands (CWs) conventional wastewater treatments cyclophosphamide cytostatic drug determination of pharmaceuticals determining target pollutants in plant materials development of methods ecotoxicity electrochemical oxidation electromigration techniques endocrine disrupting compounds environmental and biological samples environmental contaminants environmental pollution environmental risk assessment fate in the environment fate in WWTPs fluoxetine green chemistry hydroponic cultivation ifosfamide intermediates ionic liquids LC-MS/MS analysis lincomycin mianserin migration monensin municipal wastewater treatment plants paroxetine pharmaceutical residues pharmaceuticals pharmaceuticals in the environment pharmaceuticals occurrence pharmaceuticals toxicity poultry farms removal efficiency residual risk assessment roxarsone sample preparation sertraline sewage sludge soil solid phase extraction Spirotox spread of resistance sul genes sulfamethoxazole sulfonamides tetracyclines toxicity ultra-high performance liquid chromatography wastewater wastewater treatment plants (WWTPs) wastewaters |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557113103321 |
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Kumirska Jolanta
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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The Application of Quantum Mechanics in Reactivity of Molecules
| The Application of Quantum Mechanics in Reactivity of Molecules |
| Autore | Sousa Sérgio F |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 online resource (182 p.) |
| Soggetto topico | Research & information: general |
| Soggetto non controllato |
[NiFeSe] hydrogenase
antioxidants chemical kinetics chemical reactivity theory concerted rotation of the hydroxyl groups condensed phase conformational mobility coordination complexes depressive disorder DFT DFT calculations dispersion donor-acceptor systems electronic structure first-principles calculations fluoxetine Fourier transform infrared (FTIR) frequencies free radical scavengers HSAB principle hydroxyl group information theory major master equation mechanical properties n/a nanostructures optical properties oxidative stress partial electronic flows phase-current relations porphyrins, density functional theory Pyrophosphate quantum mechanics quantum mechanics (QM)/molecular mechanics (MM), geometry optimizations quantum technology quantum-chemical calculations Quercetin molecule reaction rate reactive oxygen species regional complementarity rule RRKM theory scanning tunneling microscopy self-assembly solid state subsystem phases surfaces transition state vibrational frequency analyses virial theorem |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557762903321 |
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Sousa Sérgio F
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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