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A Personalized Medicine Approach to the Diagnosis and Management of Autism Spectrum Disorder
| A Personalized Medicine Approach to the Diagnosis and Management of Autism Spectrum Disorder |
| Autore | Frye Richard E |
| Pubbl/distr/stampa | Basel, : MDPI Books, 2022 |
| Descrizione fisica | 1 electronic resource (416 p.) |
| Soggetto topico |
Medicine
Neurosciences |
| Soggetto non controllato |
fecal metabolites
ASD microbiome gastrointestinal symptoms Fisher Discriminant Analysis digital biomarkers wearables time series analysis autism social dyads socio-motor parameters network connectivity non-linear complex dynamics stochastic analysis autism spectrum disorders copy number variants females Array-Comparative Genomic Hybridization (Array-CGH) autism spectrum disorder Ehlers-Danlos syndrome hypermobility spectrum disorders autonomic disorder mast cell activation syndrome genetic testing chromosomal microarray analysis whole exome sequencing whole genome sequencing clinical utility polygenic risk scores Temple Grandin biomarker omics precision medicine proteomics transcriptomics epigenetics metabolomics patient stratification mitochondria oxidative stress prenatal environment immune dysfunction immunoglobulin G intravenous immunoglobulin energy metabolism fatty acid oxidation acyl-carnitines resveratrol integrative model concomitant condition disorder autism spectrum disorder (ASD) genomics personalized treatment strategy single nucleotide polymorphisms clinical decision support tool ADHD PANDAS OCD anxiety folate receptor alpha folates pregnancy brain development fetal development cobalamin glutathione methylation methylcobalamin redox metabolism locked-in network syndrome resting-state functional magnetic resonance imaging temporal lobe epilepsy amygdala brain COVID-19 children cytokines flavonoids inflammation luteolin mast cells microglia SARS-CoV-2 stress nutraceuticals survey vitamins minerals B12 folinic acid quality of life parents intervention systematic review medical claims logistic regression analysis retrospective analysis associated risk monoamine neurotransmitters neurotransmitter deficiency cerebral folate deficiency folate receptor alpha autoantibodies leucovorin α-amylase cortisol heart rate variability neuromodulation sleep anxiety transdermal electrical neuromodulation neurostimulation |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910595075503321 |
Frye Richard E
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| Basel, : MDPI Books, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Abiotic Stress Effects on Performance of Horticultural Crops / Alessandra Francini, Luca Sebastiani
| Abiotic Stress Effects on Performance of Horticultural Crops / Alessandra Francini, Luca Sebastiani |
| Autore | Francini Alessandra |
| Pubbl/distr/stampa | Basel, Switzerland : , : MDPI, , 2019 |
| Descrizione fisica | 1 electronic resource (126 p.) |
| Soggetto non controllato |
heat
polyphenols stomatal conductance shelf-life transpiration productivity transcription ornamental plants cold green areas flowering agronomic tools gas exchange ornamental prolonged storage transpiration greenhouse production dormancy temperature irradiance chilling requirements qPCR phenolics lodging hypoxia salinity relative humidity signal transduction chlorophyll fluorescence leaf water saturation deficit solar radiation plant choice partial root zone drying drought electro-conductivity growth flavonoids transpiration efficiency cloning oxidative stress breeding |
| ISBN |
9783039217519
3039217518 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910367747703321 |
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Francini Alessandra
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| Basel, Switzerland : , : MDPI, , 2019 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Agricultural and Food Waste : Analysis, Characterization, and Extraction of Bioactive Compounds and Their Possible Utilization
| Agricultural and Food Waste : Analysis, Characterization, and Extraction of Bioactive Compounds and Their Possible Utilization |
| Pubbl/distr/stampa | Basel, Switzerland : , : MDPI - Multidisciplinary Digital Publishing Institute, , 2020 |
| Descrizione fisica | 1 electronic resource (83 pages) |
| Soggetto topico |
Research
Biology Food - Social aspects |
| Soggetto non controllato |
Natural red pigment
Monascus purpureus Brewer’s spent grain Submerged fermentation Plackett-Burman design Chemical characterization X-ray photoelectron spectroscopy (XPS) Fourier-transform infrared spectroscopy (FTIR) Cucumis melo polyphenols flavonoids antioxidants by-products waste valorization LC-MS/MS fatty acids antioxidant activity reutilization of food waste salted egg white ovalbumin extraction aqueous two-phase flotation cork volatile compounds aroma waste bioactive compounds food waste functional foods characterization and extraction phytochemicals climatic change phenolic compounds |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | Agricultural and Food Waste |
| Record Nr. | UNINA-9910557108403321 |
| Basel, Switzerland : , : MDPI - Multidisciplinary Digital Publishing Institute, , 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Anti-inflammatory Activity of Plant Polyphenols 2.0
| Anti-inflammatory Activity of Plant Polyphenols 2.0 |
| Autore | Dell'Agli Mario |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 electronic resource (120 p.) |
| Soggetto topico |
Medicine
Pharmacology |
| Soggetto non controllato |
flavonoids
inflammation p53 cancer prevention Nrf2 pathway anti-oxidant verbascoside polyphenols insulin-producing cells diabetes UPR oxidative stress ER-stress PERK anti-inflammatory mitochondria antioxidants marine algae anti-viral activity mechanism of action Antirhea borbonica kidney fibrosis caffeic acid antioxidant enzymes DESI-imaging curcumin glioblastoma cells radiation |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910576880903321 |
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Dell'Agli Mario
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Anticancer Agents : Design, Synthesis and Evaluation
| Anticancer Agents : Design, Synthesis and Evaluation |
| Autore | Chen Qiao-Hong |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 electronic resource (606 p.) |
| Soggetto topico | Medicine |
| Soggetto non controllato |
benzofurans
chemical synthesis cytotoxic properties HeLa MOLT-4 K562 anticancer anti-neuroinflammation coumarin dihydroartemisinin flavonoids allene E-stereoselective regioselective anti-cancer activity cyanopyridone substituted pyridine pyridotriazine pyrazolopyridine thioxotriazopyridine anticancer activity HepG2 antitumor activity computational docking MDM2-p53 interaction xanthones yeast-based assays estrone derivatives hydrazine N-substituted pyrazoline anti-ovarian cancer topoisomerase II inhibitor kinase inhibitor antiproliferative agent urea synthesis antiproliferative activity apoptosis indoleamine 2,3-dioxygenase inhibitor anti-tumor immune modulation tryptophan metabolism taxoids βIII-tubulin P-glycoprotein drug resistance thiopene thienopyrimidinone thiazolidinone breast cancer benzofuran–pyrazole nanoparticles cytotoxic activity PARP-1 inhibition 3,6-dibromocarbazole 5-bromoindole carbazole actin migration Thienopyrimidine Pyrazole PI3Kα inhibitor quinazolin-4(3H)-one quinazolin-4(3H)-thione Schiff base antioxidant activity DFT study ortho-quinones beta-lapachone tanshione IIA PI3Ks PI3Kδ inhibitors 2H-benzo[e][1,2,4]thiadiazine 1,1-dioxide anticancer agents protein–protein interactions virtual screening mimetics drug discovery bivalency polyvalency antitumor cell cycle ovarian cancer P-MAPA IL-12 TLR signaling inflammation chemoresistance 4-(pyridin-4-yloxy)benzamide 1,2,3-triazole c-Met natural product anticancer agent zampanolide Talazoparib PARP inhibitor prodrug o-nitro-benzyl photoactivatable protecting groups salinomycin overcoming drug resistance tumor specificity synergy 5-fluorouracil gemcitabine amides/esters colchicine analogs thiocolchicine colchiceine antimitotic agents hydrates dihydropyranoindole HDAC inhibitors neuroblastoma aromatase MCF-7 NIH3T3 benzimidazole triazolothiadiazine docking ADME organosilicon compounds SILA-409 (Alis-409) SILA-421 (Alis-421) multidrug resistance (MDR) reversal ABCB1 (P-glycoprotein) colon cancer colchicine amide colchicine sulfonamide tubulin inhibitors docking studies crystal structure PROTACs protein degradation IGF-1R Src protein kinase phenylpyrazolopyrimidine enzyme inhibition molecular simulation androgen receptor prostate cancer enzalutamide apalutamide darolutamide triple-negative breast cancer cytotoxicity chrysin analogues flavonoid anticancer compounds |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | Anticancer Agents |
| Record Nr. | UNINA-9910557129103321 |
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Chen Qiao-Hong
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Antioxidant Activity of Polyphenolic Plant Extracts
| Antioxidant Activity of Polyphenolic Plant Extracts |
| Autore | Stagos Dimitrios |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 electronic resource (388 p.) |
| Soggetto topico |
Research & information: general
Biology, life sciences |
| Soggetto non controllato |
green leafy vegetables
effect of cooking polyphenols antioxidant activity Averrhoa bilimbi Oxalidaceae DPPH xanthine oxidase LC-QTOF-MS/MS molecular docking tentative bioactive constituents Dialium indum exocarp seed antioxidant phenolic acids amino acids GC-MS analysis AGN FIR phenolic flavonoid antioxidant capacity antimicrobial activity polyphenol compounds bixin rosemary extracts method validation HPLC food matrices fruit vinegar phenolics organic acid Ladastacho characterisation properties HPLC/ESI-MS HS-SPME/GC-MS beneficial use antimicrobial hydroxytyrosol rosemary pomegranate fish volatile compounds Rosa canina Rosa sempervivens Pyrocantha coccinea antioxidants endothelial cells glutathione almond skins bioavailability waste by-products flavonoids oxidative stress human reactive oxygen species proinflammatory cytokines Alzheimer's disease cornelian cherry anthocyanins gastrointestinal digestion Opuntia ficus-indica cladode antibiofilm activity olive Olea europaea anthocyanin cyanidin 3-glucoside cyanidin 3-rutinoside oxygen radical absorbance capacity (ORAC) high performance liquid chromatography mass spectrometry (HPLC-MS) tea Camellia sinensis polyphenol catechin caffeine theaflavine insulin resistance diabetes olive oil phenols antidiabetic myrtle ultrasound-assisted extraction phenolic compounds liquid chromatography analysis mass spectrometry mulberry (Morus nigra Morus alba) simple sugars organic acids phenol compounds high performance liquid chromatography/diode array detector/mass spectrometry anthocyanins anti-inflammatory activity extraction central composite design optimization P. officinalis phytochemicals cytotoxicity α-amylase inhibition red-osier dogwood antioxidative effect H2O2 transepithelial resistance (TEER) Caco-2 cells Rubus idaeus L. HPLC-ESI-HR-qTOF-MS/MS antioxidant activities digestive enzymes inhibitors molecular docking analysis olive mill wastewater encapsulation maltodextrin whey protein gelatin spray drying diabetes mellitus Lamiaceae alpha-glucosidase alpha-amylase Salvia africana-lutea terpenoids cape floristic region |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557728403321 |
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Stagos Dimitrios
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Antioxidant Capacity of Anthocyanins and other Vegetal Pigments: Modern Assisted Extraction Methods and Analysis
| Antioxidant Capacity of Anthocyanins and other Vegetal Pigments: Modern Assisted Extraction Methods and Analysis |
| Autore | Asuero Agustín G |
| Pubbl/distr/stampa | MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 electronic resource (260 p.) |
| Soggetto topico |
Research & information: general
Chemistry Analytical chemistry |
| Soggetto non controllato |
maqui berry extract
preservation methods antioxidant activity polyphenols and anthocyanins content oxidative stress inflammation RAW 264.7 cells HT-29 cells inflammatory bowel disease anthocyanins Box-Behnken design purple potato red potato Solanum tuberosum ultrasound-assisted extraction optimization UHPLC DPPH antioxidants carotenoids chlorophylls extraction methods novel analytical technologies metabolomics mass spectrometry metabolism pathways pigments Diospyros kaki in vitro digestion probiotic bacterial fermentation bioactive compounds Allium cepa L. Box-Behnken onion phenolic compounds non-thermal technologies grapes wine HHP UHPH PEFs US irradiation stability degradation health benefit cranberry anthocyanidin UPLC Vaccinium macrocarpon non-conventional extraction techniques anthocyanin yields industrial application anthocyanin phenylalanine prohydrojasmon flavonoids mango apples preharvest red color fruit quality blood oranges bilberry natural habitats polyphenol different geographical locations |
| ISBN | 3-0365-5253-7 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | Antioxidant Capacity of Anthocyanins and other Vegetal Pigments |
| Record Nr. | UNINA-9910619465303321 |
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Asuero Agustín G
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| MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Antioxidants in Cocoa
| Antioxidants in Cocoa |
| Pubbl/distr/stampa | Basel, Switzerland : , : MDPI - Multidisciplinary Digital Publishing Institute, , 2021 |
| Descrizione fisica | 1 electronic resource (170 pages) |
| Soggetto topico |
Research
Biology Food - Social aspects |
| Soggetto non controllato |
cocoa
chocolate polyphenols antioxidants melanoidins theobroma cacao L. total phenolic compounds antioxidant capacity metal-chelating ability fourier transform infrared spectroscopy flavan-3-ol procyanidin α-glucosidase melanoidin Maillard reaction (-)-epicatechin borderline hypertensive rats nitric oxide redox balance iron Nrf2 PPAR-γ open field cocoa by-products cherry extract oxidative stress human endothelial cell roasting catechin epicatechin total phenolic content Criollo cocoa kinetic flavonoids cocoa extract ischemia-reperfusion injury apoptosis inflammatory markers conching milk chocolate milk powder protein antioxidant activity solid-liquid kinetic extraction polyphenol oxidase cocoa polyphenols heat treatment enzyme inactivation |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557141503321 |
| Basel, Switzerland : , : MDPI - Multidisciplinary Digital Publishing Institute, , 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Antioxidants in Foods
| Antioxidants in Foods |
| Autore | Seiquer Isabel |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 electronic resource (418 p.) |
| Soggetto topico |
Research & information: general
Biology, life sciences Food & society |
| Soggetto non controllato |
green tea extract
food processing tannase ultrasound antioxidant activity liver injury acclimatisation antioxidant defences chlorophyll fluorescence in vitro culture peroxidase stevia plants 7S basic globulins anti-inflammatory protein antioxidant protein cytokines glutathione iNOS nitric oxide oxidative stress sweet lupins group home-cooking extra virgin olive oil UPLC-ESI-QqQ-MS/MS healthy cooking Mediterranean diet phenolic compounds bioactive compounds functional pasta gluten-free pasta bioaccessibility bioavailability whole grain composite flour legumes food by-products avocados (Persea americana Mill.) low temperatures plastochromanol-8 tocotrienols tocopherols tocochromanols kombucha tea fermentation antioxidant flavonoids polyphenols ascorbic acid chlorophyll and carotenoid content biodiversity Capsicum annuum L. β-carotene statistical analysis rye bread microencapsulation phenolics in vitro relative bioaccessibility lipoxygenase cyclooxygenase acetylcholinesterase biological activity lycopene antioxidants cancer diabetes cardiovascular diseases skin disorders free radicals spectrophotometer limitations chemical reactions colorimetry anthraquinone free radical scavenging inflammatory cytokines apoptosis Rumex crispus skins seeds Vitis vinifera cyclic voltammetry anthocyanin metabolites cardioprotection hepatoprotection nephroprotection neuroprotection antioxidant peptides element of pork carcasses spectrometric analysis ascorbate ascorbate-glutathione cycle capsaicin catalase dihydrocapsaicin NADP-dehydrogenases superoxide dismutase red cabbage in vitro gastrointestinal digestion acid-resistant capsule UHPLC-Q-Orbitrap HRMS apples reducing and chelating capacity HPLC-DAD-MS/MS Dillenia indica heme oxygenase 1 (HO-1) nuclear factor erythroid 2-related factor 2 (Nrf2) RAW 264.7 cells apo-carotenals bone osteoclasts NFκB synergy |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557728503321 |
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Seiquer Isabel
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Antitumor and Anti-HIV Agents from Natural Products
| Antitumor and Anti-HIV Agents from Natural Products |
| Autore | Nakagawa-Goto Kyoko |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 |
| Descrizione fisica | 1 electronic resource (338 p.) |
| Soggetto topico | Research & information: general |
| Soggetto non controllato |
natural phaeosphaeride A
antitumor activity human tumor cell lines HEF cell line acute toxicity aspidosperma-type monoterpenoid indole alkaloids antiproliferative activity tubulin inhibitor Bousigonia mekongensis ursolic acid DOTA triterpenoids cytotoxicity diterpenoid alkaloids human tumor cells lipojesaconitine delcosine delpheline kobusine pseudokobusine BRAF inhibitor Mentha aquatica var. Kenting Water Mint essential oil chemoprevention two-stage skin carcinogenesis melanoma curcumin analog apoptosis oxidative stress drug–drug interaction tamoxifen taxol cisplatin Artemisia absinthium L. antioxidants total phenolic content melanoma and breast cancer cell line HaCaT cells inflammation breast cancer cell cycle flavonoids reactive oxygen species tumor suppression antiretroviral agents anti-HIV marine metabolites natural products drug development Ivalin Carpesium divaricatum hepatocellular carcinoma mitochondria-mediated apoptosis NF-κB Hernandia nymphaeifolia butanolides lignan glycosides coumarins antiangiogenic cancer natural agents chemistry medicine cancer stem cell cervical cancer pterostilbene resveratrol caffeic acid cancer multidrug resistance P-glycoprotein phenolic acid oxypeucedanin Angelica dahurica antiproliferation G2/M phase cell cycle arrest p53 SK-Hep-1 hepatoma cells allyl isothiocyanate benzyl isothiocyanate sulforaphane phenethyl isothiocyanate bladder cancer quercetin oral squamous cell carcinoma cells metastasis cell cycle arrest epithelial-to-mesenchymal transition matrix metalloproteinase transforming growth factor-β1 β-lapachone |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557504803321 |
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Nakagawa-Goto Kyoko
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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