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Advances in Antifungal Development: Discovery of New Drugs and Drug Repurposing
| Advances in Antifungal Development: Discovery of New Drugs and Drug Repurposing |
| Autore | Kim Jong Heon |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 electronic resource (282 p.) |
| Soggetto topico |
Research & information: general
Biology, life sciences |
| Soggetto non controllato |
nanoparticles
fungi drug delivery systems marine biological synthesis myconanotechnology canesten clotrimazole vulvovaginal vaginitis mycosis candidosis yeast infection candida candida albicans vaginal health anticandidal activity indazole pyrazole 3-phenyl-1H-indazole drug design acetylsalicylic acid (ASA, aspirin) capsule CAP64 Cryptococcus membrane potential (ΔΨM) photodynamic treatment photosensitiser ultrastructure drug repurposing antifungals repositioning yeasts emerging fungi multidrug resistance therapeutic alternatives new targets Candida auris Aspergillus spp antifungal beta-glucan polycations Galleria mellonella model retinoids Candida spp onychomycosis Malassezia spp dermatophytes microbiology mycology all-trans retinoic acid Acanthamoeba free-living ameba Acanthamoeba keratitis isavuconazonium sulfate cyst drug drug discovery drug targets invasive aspergillosis treatment invasive fungal infections fission yeast cell wall β(1,3)-D-glucan synthase antifungal drugs echinocandin drugs echinocandin resistance Fks resistance hot spots cytokinesis septation cell separation cell integrity cell lysis sporotrichosis Felis catus quinones hydrazones zoonoses host-directed drug therapy azoles polyenes echinocandins viral infections azole synergy resistance Candida natural products |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | Advances in Antifungal Development |
| Record Nr. | UNINA-9910585935503321 |
Kim Jong Heon
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Symmetry Breaking in Cells and Tissues
| Symmetry Breaking in Cells and Tissues |
| Autore | Goryachev Andrew |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 electronic resource (322 p.) |
| Soggetto topico |
Research & information: general
Biology, life sciences |
| Soggetto non controllato |
actin waves
curved proteins dynamic instability podosomes diffusion cell polarity Cdc42 stress cellular memory phase separation prions apoptotic extrusion oncogenic extrusion contractility actomyosin bottom-up synthetic biology motor proteins pattern formation self-organization cell motility signal transduction actin dynamics intracellular waves polarization direction sensing symmetry-breaking biphasic responses reaction-diffusion membrane and cortical tension cell fusion cortexillin cytokinesis Dictyostelium myosin symmetry breaking cytoplasmic flow phase-space analysis nonlinear waves actin polymerization bifurcation theory mass conservation spatial localization activator–inhibitor models developmental transitions cell polarization mathematical model fission yeast reaction–diffusion model small GTPases Cdc42 oscillations pseudopod Ras activation cytoskeleton chemotaxis neutrophils natural variation modelling activator-substrate mechanism mass-conserved models intracellular polarization partial differential equations sensitivity analysis GTPase activating protein (GAP) fission yeast Schizosaccharomyces pombe CRY2-CIBN optogenetics clustering positive feedback network evolution Saccharomyces cerevisiae polarity modularity neutrality |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557440703321 |
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Goryachev Andrew
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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