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Chemical Biology of Sterols, Triterpenoids and Other Natural Products: A Themed Issue in Honor of Professor W. David Nes on the Occasion of His 65th Birthday
| Chemical Biology of Sterols, Triterpenoids and Other Natural Products: A Themed Issue in Honor of Professor W. David Nes on the Occasion of His 65th Birthday |
| Autore | Guo De-an |
| Pubbl/distr/stampa | MDPI - Multidisciplinary Digital Publishing Institute, 2019 |
| Descrizione fisica | 1 electronic resource (256 p.) |
| Soggetto non controllato |
high-fat high-carbohydrate diet
toxicity oxysterol squalene cyclase sterol content sterolomics Polystichum Smith-Lemli-Opitz syndrome antifungals alkaloid cycloartenol synthase degeneration phytosterol Rhizopus arrhizus fibroblasts pod-blast fern cholesterol cytotoxic activity N-methylpiperidine. reductive deamination genetic disease isoprenoid steroid atherosclerosis granatane antioxidant wound healing development enzyme-assisted derivatization maturity terpene keratinocytes C4-demethylation complex (C4DMC) ?-sitosterol mesocarp sterol biosynthesis mechanism-based inactivators Mucorales gas chromatography-mass spectrometry (GC-MS) Girard reagent ROS sterol pattern N-methylcadaverine ?-tocopherol electrospray ionization-mass spectrometry human African trypanosomiasis HUVECs lipidomics campesterol triterpene oxyphytosterol leishmania Chagas disease LOX-1 sterol C24-methyltransferase antifungal effectivity ergosterol biosynthesis hormone glucose homeostasis retina solanaceae cholestanoic acid algal sterols cell migration withanolides insulin resistance Zingiber officinale posaconazole synthesis pre-diabetes pharmacognosy sterol 4-methylsterol oleanolic acid antiparasitic drugs lupeol oilseed aurelianolides divalent metal co-factor ligation bile alcohol phytosterols azoles infectious disease gingerols UV-radiation oil bodies ZnO sterol 14?-demethylase stigmasterol |
| ISBN | 3-03897-417-X |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | Chemical Biology of Sterols, Triterpenoids and Other Natural Products |
| Record Nr. | UNINA-9910346835903321 |
Guo De-an
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| MDPI - Multidisciplinary Digital Publishing Institute, 2019 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Cytobiology of Human Prostate Cancer Cells and Its Clinical Applications
| Cytobiology of Human Prostate Cancer Cells and Its Clinical Applications |
| Autore | Ishii Kenichiro |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 |
| Descrizione fisica | 1 electronic resource (184 p.) |
| Soggetto topico | Medicine |
| Soggetto non controllato |
androgen receptor
docetaxel cabazitaxel castration-resistant prostate cancer chemotherapy P-glycoprotein EPI-002 splice variant prostate-specific antigen androgen deprivation therapy time to PSA nadir fibroblasts prostate cancer androgen sensitivity pirfenidone TGFβ1 G1 cell cycle arrest fibroblast growth factor fibroblast growth factor receptor obesity inflammation immune cells cytokine high-fat diet KIFC1 docetaxel resistance apoptosis CW069 Caveolin-1 TP53-regulated inhibitor of apoptosis 1 tumour stroma tumour microenvironment fibroblast CAF resistance radiotherapy CCL2 CCL22 CCL5 migration LSD1 epigenetics autophagy abiraterone enzalutamide testosterone castration resistant prostate cancer animal model diet fat in vitro in vivo mouse AKR1C3 hormone-naïve prostate cancer immunohistochemistry tissue microarray androgen receptor dependency fibroblast-dependent androgen receptor activation |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557116703321 |
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Ishii Kenichiro
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Disease and the Hippo Pathway: Cellular and Molecular Mechanisms
| Disease and the Hippo Pathway: Cellular and Molecular Mechanisms |
| Autore | Hansen Carsten Gram |
| Pubbl/distr/stampa | MDPI - Multidisciplinary Digital Publishing Institute, 2019 |
| Descrizione fisica | 1 electronic resource (226 p.) |
| Soggetto non controllato |
STRIPAK
skin cancer Lats2 transcription myofibroblast epigenetic Hippo cancer immunity TAZ Taz TAZ (transcriptional co-activator with PDZ-binding motif) adaptive immunity fibroblasts innate immunity LATS MST (mammalian STE20-like protein kinase) phosphorylation stem cells wound healing signal transduction angiogenesis LATS1/2 EMT protein-protein interactions structure biology Hippo pathway hippo pathway autoimmunity Mps one binder YAP/TAZ GPCR fibrosis MST1/2 YAP (yes-associated protein) YAP Yap protein kinase LATS (large tumor suppressor kinase) peripheral nerve sheath tumor signal cross-talk stem cell skin development STK38 tumorigenesis NDR schwannoma G protein-coupled receptor anti-cancer therapy feedback loops vascular mimicry castration resistance chromatin Hippo signalling ECM MST prostate cancer TEAD cancer zebrafish |
| ISBN | 3-03921-777-1 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | Disease and the Hippo Pathway |
| Record Nr. | UNINA-9910367742003321 |
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Hansen Carsten Gram
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| MDPI - Multidisciplinary Digital Publishing Institute, 2019 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Impaired Mitochondrial Bioenergetics under Pathological Conditions
| Impaired Mitochondrial Bioenergetics under Pathological Conditions |
| Autore | Lenaz Giorgio |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 electronic resource (460 p.) |
| Soggetto topico |
Research & information: general
Biology, life sciences Biochemistry |
| Soggetto non controllato |
aging heart
Bcl-2 family mitochondria programmed cell death fatty acid oxidation palmitate oleate m.3243A> G mutation MT-ATP6 m.8909T> C ATP synthase nephropathy oxidative phosphorylation mitochondrial disease cardiolipin Barth syndrome Sengers syndrome respiratory chain Dilated Cardiomyopathy with Ataxia cardiomyopathy mammalian complex I NADH dehydrogenase complex I assembly complex I structure complex I deficiency supernumerary subunits electron transport chain mitochondrial dysfunction Leigh syndrome mitochondrial diseases yeast Saccharomyces cerevisiae pet mutants pancreatic endocrine cells mathematical model cellular bioenergetics diabetes glucagon insulin exercise immune system metabolic disease COVID-19 mitochondrial dynamics viral infections MAVS RIG-I MDA5 innate immune response SARS CoV-2 RSV influenza respiratory supercomplexes ROS ATP synthase/hydrolase mitochondrial permeability transition pore cristae cellular signaling human disease mitochondrial dynamic cell signaling cancer respiratory complexes oxidative stress mitochondrial DNA MTCYB mutations cytochrome b complex III aging energy metabolism entorhinal cortex lipoxidation-derived damage neurodegeneration oxidative damage protein import respiratory complex assembly supercomplexes mitochondrial proteostasis heart failure bioenergetics assembly factor atypical myopathy high-resolution respirometry toxicity assays cell culture equine primary myoblasts fibroblasts frozen tissue leukocytes oxygen consumption platelets respirometry skeletal muscle |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910585934503321 |
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Lenaz Giorgio
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Novel Natural-based Biomolecules Discovery for Tackling Chronic Diseases
| Novel Natural-based Biomolecules Discovery for Tackling Chronic Diseases |
| Autore | Kwok Hang Fai |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 electronic resource (180 p.) |
| Soggetto topico |
Humanities
Social interaction |
| Soggetto non controllato |
DAPK1
SUMO SENP protein degradation post-translational modification amphibian Bowman-Birk inhibitor Tat peptide molecular cloning antifungal drug design protease inhibitor natural-based compound anticancer therapy lung cancer survivin apoptosis STAT3 colorectal cancer orientin cell cycle arrest Bcl-2 family proteins Astragalus membranaceus insulin PI3K AKT PPARγ PDX-1 Petasites japonicus Asteraceae lignan anti-inflammation NO PGE2 iNOS COX-2 molecular docking peptides kynurenines binding affinity μ-opioid receptor pharmacophore G-protein activation fucoidan PLGA docetaxel drug delivery system anticancer therapy/cancer treatment hIAPP amyloidogenesis insulin granules endoplasmic reticulum anionic lipids F23R variant β-sheet transitions β-cell cytotoxicity unfolded protein response pomegranate punicalagin tannins gingiva fibroblasts antioxidant wound healing branched-chain fatty acids Conidiobolus heterosporus peroxisome proliferator-activated receptor α lipid metabolism fatty acid oxidation hepatocyte |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557607403321 |
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Kwok Hang Fai
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Peptides for Health Benefits 2019 : Volume 2
| Peptides for Health Benefits 2019 : Volume 2 |
| Autore | Hernández-Ledesma Blanca |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 |
| Descrizione fisica | 1 electronic resource (342 p.) |
| Soggetto topico |
Research & information: general
Biology, life sciences |
| Soggetto non controllato |
antihypertensive peptides
functional food food-derived fermentation Chlorella sorokiniana in silico BIOPEP-UWM database proteomics bioactive peptides nano liquid chromatography tandem mass spectrometry (nanoLC-nanoESI MS/MS) apolipoprotein E amyloid fibrils Alzheimer's disease Αβ oligomer amyloid Aβ peptide glioma platelets antiproliferative assay conjugation docetaxel doxorubicin extra domain B fibronectin Fmoc/tBu peptide-drug conjugate prostate cancer solid-phase synthesis targeting acrylamide enteric nervous system galanin pig stomach formyl peptide receptors ligands diseases polymicrobial biofilms intragenic antimicrobial peptide Hs02 Pseudomonas aeruginosa Staphylococcus aureus osteostatin arthritis inflammation immune response cartilage destruction bone erosion collagen hydrolysis enzyme molecular weight sheepskin NF-κB dry-cured pork ham angiotensin I converting enzyme endothelial dysfunction molecular blind docking Lactoferricin B (Lfcin B) Histatin-5 antimicrobial peptides (AMPs) antifungal activity proteome microarray synergy temporin MRSA antimicrobial peptide human keratinocytes pseudin-2 antisepsis, peptide antibiotics neurotensin asthma T cells In situ tetramer staining MHC tetramer antigen-specific confocal microscopy fresh tissue velvet antler alcalase hydrolysate antioxidant peptide protection ability oxidative stress Crassostrea angulata pidotimod CXCR3 monocyte migration PI3K/Akt pathway T cell immunomodulant host defense peptides membrane activity copper piscidins Clostridioides difficile prolactin-releasing peptide GPR10 RF-amide peptides food intake regulation energy expenditure neuroprotection signaling gender differences dyslipidemia obesity hyperglycemia pulmonary emphysema endothelial progenitor cells angiogenic precursor cells pegylated glucagon-like peptide 1 and endothelial regeneration miiuy croaker (Miichthys miiuy) swim bladder FPYLRH antioxidant activity cytoprotective effect antimicrobial peptides antimicrobial resistance AMP identification and design biosynthesis mode of action physico-chemical properties therapeutic potential insects Cecropins Cec-analogs MDR infectious diseases airway inflammation non-atopic asthma hybrid peptide pro-inflammatory cytokines sPLA2 MDA database proteolysis SMILES code foods nutrition chronic diseases nutraceuticals peptide vaccine immune checkpoint inhibitor humanized mouse cancer antigen immune suppression vasoactive intestinal peptide VPAC1 receptor VPAC2 receptor rheumatic diseases inflammatory bowel disease central nervous system diseases type 1 diabetes Sjögren's syndrome biomarkers human antimicrobial peptides defensins cathelicidins anti-inflammatory pro-inflammatory peptide combinatorial library library design screening mutagenesis prolyl-hydroxyproline (Pro-Hyp) hydroxyprolyl-glycine (Hyp-Gly) collagen peptide fibroblasts fetal bovine serum (FBS) AMD CNV VEGFR1 multimeric peptides oral delivery colorectal cancer cancer stem cells chemoprevention bioactive peptide lunasin ACE-inhibitory activity whey peptides molecular docking hypertension antibiotic resistance cystic fibrosis cryptides anti-biofilm peptides synergistic effects |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | Peptides for Health Benefits 2019 |
| Record Nr. | UNINA-9910557492903321 |
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Hernández-Ledesma Blanca
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Peptides for Health Benefits 2019 : Volume 1
| Peptides for Health Benefits 2019 : Volume 1 |
| Autore | Hernández-Ledesma Blanca |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 |
| Descrizione fisica | 1 electronic resource (340 p.) |
| Soggetto topico |
Research & information: general
Biology, life sciences |
| Soggetto non controllato |
antihypertensive peptides
functional food food-derived fermentation Chlorella sorokiniana in silico BIOPEP-UWM database proteomics bioactive peptides nano liquid chromatography tandem mass spectrometry (nanoLC-nanoESI MS/MS) apolipoprotein E amyloid fibrils Alzheimer's disease Αβ oligomer amyloid Aβ peptide glioma platelets antiproliferative assay conjugation docetaxel doxorubicin extra domain B fibronectin Fmoc/tBu peptide-drug conjugate prostate cancer solid-phase synthesis targeting acrylamide enteric nervous system galanin pig stomach formyl peptide receptors ligands diseases polymicrobial biofilms intragenic antimicrobial peptide Hs02 Pseudomonas aeruginosa Staphylococcus aureus osteostatin arthritis inflammation immune response cartilage destruction bone erosion collagen hydrolysis enzyme molecular weight sheepskin NF-κB dry-cured pork ham angiotensin I converting enzyme endothelial dysfunction molecular blind docking Lactoferricin B (Lfcin B) Histatin-5 antimicrobial peptides (AMPs) antifungal activity proteome microarray synergy temporin MRSA antimicrobial peptide human keratinocytes pseudin-2 antisepsis, peptide antibiotics neurotensin asthma T cells In situ tetramer staining MHC tetramer antigen-specific confocal microscopy fresh tissue velvet antler alcalase hydrolysate antioxidant peptide protection ability oxidative stress Crassostrea angulata pidotimod CXCR3 monocyte migration PI3K/Akt pathway T cell immunomodulant host defense peptides membrane activity copper piscidins Clostridioides difficile prolactin-releasing peptide GPR10 RF-amide peptides food intake regulation energy expenditure neuroprotection signaling gender differences dyslipidemia obesity hyperglycemia pulmonary emphysema endothelial progenitor cells angiogenic precursor cells pegylated glucagon-like peptide 1 and endothelial regeneration miiuy croaker (Miichthys miiuy) swim bladder FPYLRH antioxidant activity cytoprotective effect antimicrobial peptides antimicrobial resistance AMP identification and design biosynthesis mode of action physico-chemical properties therapeutic potential insects Cecropins Cec-analogs MDR infectious diseases airway inflammation non-atopic asthma hybrid peptide pro-inflammatory cytokines sPLA2 MDA database proteolysis SMILES code foods nutrition chronic diseases nutraceuticals peptide vaccine immune checkpoint inhibitor humanized mouse cancer antigen immune suppression vasoactive intestinal peptide VPAC1 receptor VPAC2 receptor rheumatic diseases inflammatory bowel disease central nervous system diseases type 1 diabetes Sjögren's syndrome biomarkers human antimicrobial peptides defensins cathelicidins anti-inflammatory pro-inflammatory peptide combinatorial library library design screening mutagenesis prolyl-hydroxyproline (Pro-Hyp) hydroxyprolyl-glycine (Hyp-Gly) collagen peptide fibroblasts fetal bovine serum (FBS) AMD CNV VEGFR1 multimeric peptides oral delivery colorectal cancer cancer stem cells chemoprevention bioactive peptide lunasin ACE-inhibitory activity whey peptides molecular docking hypertension antibiotic resistance cystic fibrosis cryptides anti-biofilm peptides synergistic effects |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | Peptides for Health Benefits 2019 |
| Record Nr. | UNINA-9910557631703321 |
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Hernández-Ledesma Blanca
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Sex Hormone Receptor Signals in Human Malignancies
| Sex Hormone Receptor Signals in Human Malignancies |
| Autore | Miyamoto Hiroshi |
| Pubbl/distr/stampa | MDPI - Multidisciplinary Digital Publishing Institute, 2019 |
| Descrizione fisica | 1 electronic resource (152 p.) |
| Soggetto non controllato |
FOXA1
COBRA1 estrogen progesterone receptor negative mutational profiling heterogeneous nuclear ribonucleoprotein K estrogen receptor alpha salivary gland tumors castration-resistant prostate cancer ELK1 fibroblasts androgen receptor melanocytes drug screening and proteomics PI3K pathway NELFB therapeutic targets immunohistochemistry androgen deprivation therapy ovarian cancer estrogen receptor epidermal growth factor receptor ethinylestradiol melanoma breast cancer keratinocytes G-protein coupled estrogen receptor prognosis levonorgestrel ultraviolet radiation sex hormone receptors upper urinary tract urothelial carcinoma CRPC nuclear factor erythroid 2-related factor 2 TP53 |
| ISBN | 3-03921-174-9 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910367756503321 |
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Miyamoto Hiroshi
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| MDPI - Multidisciplinary Digital Publishing Institute, 2019 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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The Effect of Diet and Natural Agents on Oral, Periodontal Health and Dentistry
| The Effect of Diet and Natural Agents on Oral, Periodontal Health and Dentistry |
| Autore | Isola Gaetano |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 |
| Descrizione fisica | 1 electronic resource (102 p.) |
| Soggetto topico | Medicine |
| Soggetto non controllato |
periodontitis
Pelargonium sidoides DC root extract proanthocyanidins bacteriotoxicity inflammatory cytokines gene expression fibroblasts macrophages leukocytes vitamin C retinol α-carotene β-carotene β-cryptoxanthin γ-tocopherol lutein zeaxanthin lycopene ischemic heart disease C-reactive protein cardiovascular disease clinical trial dietary supplements dental implants osseointegration vitamin D magnesium resveratrol ascorbic acid zinc calcium bone diabetes mellitus periodontal disease natural agents gingivitis antioxidants vitamins oolong tea phenolic profile salivary microbiota 16S rRNA sequencing bacterial diversities correlation network oral diseases diet nutrients nutraceutics therapy host response |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557103003321 |
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Isola Gaetano
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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The Tumor Microenvironment of High Grade Serous Ovarian Cancer
| The Tumor Microenvironment of High Grade Serous Ovarian Cancer |
| Autore | Kenneth P. Nephew (Ed.) |
| Pubbl/distr/stampa | MDPI - Multidisciplinary Digital Publishing Institute, 2019 |
| Descrizione fisica | 1 electronic resource (434 p.) |
| Soggetto non controllato |
ovarian cancer
transcriptomic stroma immune cells epigenetics recurrence immunotherapies chemoresistance fibroblasts metastasis genomic tumor microenvironment cancer stem cells |
| ISBN | 3-03897-555-9 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910346663003321 |
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Kenneth P. Nephew (Ed.)
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| MDPI - Multidisciplinary Digital Publishing Institute, 2019 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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