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Opioids and Their Receptors : Present and Emerging Concepts in Opioid Drug Discovery
| Opioids and Their Receptors : Present and Emerging Concepts in Opioid Drug Discovery |
| Autore | Spetea Mariana |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 |
| Descrizione fisica | 1 online resource (358 p.) |
| Soggetto topico | Medicine |
| Soggetto non controllato |
(−)-N-phenethylnorhydromorphone analogs
[35S]GTPgammaS assay [Dmt1]DALDA 14-methoxycodeine-6-O-sulfate 1H-NMR experiments 6β-naltrexol abuse agonist allodynia analgesia analgesics antagonist arrestin recruitment beta-arrestin bias factor biased agonism biased agonist biased agonists biased ligands biased signaling bifunctional ligands binding binding affinity BNTX buprenorphine chronic constriction injury (CCI) codeine codeine-6-O-sulfate DADLE DALDA DAMGO delta opioid receptor dependence design and synthesis dihydrocodeine diphenethylamines docking dysbiosis fentanyl forskolin-induced cAMP accumulation assays functional assay G-protein bias heteromer hyperalgesia interaction fingerprints internalization inverse agonist ischemia kappa opioid receptor KGOP01 Leu-enkephalin loperamide lysosomes macrocyclic tetrapeptide mechanism elucidation misuse mitragynine molecular docking molecular dynamics molecular modeling & MOR and DOR agonists morphinan morphine mu opioid receptor mu receptor multifunctional ligands n/a naltrexone neonatal opioid withdrawal syndrome neurokinin-1 receptor neutral antagonist NTI derivative opioid opioid drugs opioid liabilities opioid peptide opioid peptides opioid peptides and peptidomimetics opioid receptors opioid side effects opioids over-the-counter drugs pain therapy partial agonism partial agonist peptide synthesis peripheral analgesic tolerance peripheral antinociception peripheral µ-opioid receptors pharmacology plasma stability potassium channels primary hippocampal culture PZM21 racemic synthesis of β2-amino acids receptor binding studies receptor model respiration respiratory depression selectivity simulation SR-17018 structure-activity relationships sulfonamide TAPP tolerance writhing test zerumbone β-arrestin recruitment assays β2-amino acids β2-Homo-amino acids δ opioid receptor δ opioid receptor antagonist μ opioid receptor µ opioid receptor µ-opioid receptor |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | Opioids and Their Receptors |
| Record Nr. | UNINA-9910557108003321 |
Spetea Mariana
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Radiopharmaceuticals for PET Imaging - Issue A
| Radiopharmaceuticals for PET Imaging - Issue A |
| Autore | Roivainen Anne |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 |
| Descrizione fisica | 1 online resource (212 p.) |
| Soggetto topico | Medicine |
| Soggetto non controllato |
(S)-(−)-[18F]fluspidine
[11C]carfentanil [18F]AlF [18F]FACH 18F-fluorodeoxyglucose 18F-labeled analog of FACH affibody molecule AlF-radiolabelling animal model bioconjugation bioorthogonal chemistry blood-brain barrier (BBB) carfentanil clinical outcomes EGFR FACH fentanyl fluorine-18 gallium-68 image-based internal dosimetry imaging-based biomarker indium-11 infection inflammation inverse electron-demand Diels-Alder ligation isotopic exchange kinetic analysis linker MCT1/MCT4 lactate transporter inhibitor metabolic stability molecular imaging monocarboxylate transporters (MCTs) multiple myeloma naloxone nanobody NODAGA NOTA OLINDA opioid orthotopic xenograft of glioblastoma in mouse osteomyelitis overdose peptides PET PET imaging PET radiotracers pharmacokinetics PODS positron emission tomography positron emission tomography (PET) imaging positron emission tomography (PET), defluorination positron emission tomography/computed tomography preclinical development preclinical radiopharmaceutical dosimetry proteolysis radiation safety radiochemistry radiopharmaceuticals receptor occupancy Siglec-9 sigma-1 receptor availability silicon-based fluoride acceptor single-domain antibody small animal Positron Emission Tomography/Magnetic Resonance Imaging (PET/MRI) SPECT Staphylococcus aureus sub-millimetre resolution SV2A protein synaptic loss tetrazine tetrazine ligation thiol-reactive tumor imaging VAP-1 vascular adhesion protein vulnerable plaque α-CCA |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557437003321 |
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Roivainen Anne
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Recent Studies of Rodent Ultrasonic Vocalizations and Their Use in Experimental Models
| Recent Studies of Rodent Ultrasonic Vocalizations and Their Use in Experimental Models |
| Autore | Brudzynski Stefan M |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 online resource (352 p.) |
| Soggetto topico |
Medicine and Nursing
Neurosciences |
| Soggetto non controllato |
22 kHz calls
22 kHz vocalizations 22-kHz calls 50 kHz calls 50 kHz vocalizations 50-kHz calls 50-khz ultrasonic vocalizations (USVs) 6-OHDA ACTH addiction affect alarm call alpha-synuclein amphetamine animal model anxiety autism automated scoring aversion aversive state brain oscillations Brattleboro rat calcium Cav1.2 chemogenetics chronic variable stress (CVS) clozapine-n-oxide cognitive development communication corticosterone dam-pup interaction depression distress DJ1 dopamine drug development drug discovery emotional arousal emotional contagion ethanol evolution of vocalization exaggerated reactivity exercise fear contagion fear extinction female females fentanyl food generalization heart rate hedonia hyperreactivity hypervigilance individual differences infant isolation calls larynx machine learning male males maternal immune activation maternal separation mental health mesolimbic cholinergic system mesolimbic dopaminergic system microdialysis n/a negative geotaxis NOR nucleus accumbens observational fear learning opioids pain Parkinson's disease pathology pharmacology Pink1 play playback PTSD pup pup isolation rat rat pup rats respiration reward righting reflex rough-and-tumble play self-administration sex differences social approach social buffering social contact call social play ultrasonic vocalization ultrasonic vocalizations UMAP USV vasopressin antagonists vocalizations Wistar working memory Y maze |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557608903321 |
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Brudzynski Stefan M
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Research Topics in Medicines and How Our Board Members Are Engaged in Them
| Research Topics in Medicines and How Our Board Members Are Engaged in Them |
| Autore | Sakagami Hiroshi |
| Pubbl/distr/stampa | MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 online resource (480 p.) |
| Soggetto topico | Medicine |
| Soggetto non controllato |
abdominal breathing
alkaline extract of Sasa sp allergic rhinitis Angelicae Sinensis Radix anti-acetylcholinesterase anti-inflammatory antidiabetic antifouling antimicrobial antioxidant antitumor aphthous stomatitis apoptosis artificial intelligence auricular acupuncture biliary tract cancer bioactive compounds biochanin A biofilm boiogito bone metabolism BRCA breathing exercise calcium metabolism cell cycle analysis cholangiocarcinoma chromone chronic liver disease cobblestoning contrast-enhanced ultrasound coronarin D CRBSI Crohn's disease CVC daidzein Danggui detection of the precursory signs of decompensation of geriatric syndromes diagnostic algorithm diaphragmatic breathing DILI elderly patient extra-intestinal manifestations fentanyl flavonols Genista tridentata genistein genomic landscape GER-e-TEC geriatric syndromes granules granuloma annulare granulomatous disorders of the skin Hedychium hepatocellular carcinoma herb herb induced liver injury herbal medicine HILI HIV HSV human CD4+ T cells iDILI iDrug induced liver injury immune system immunity in vitro inflammation inflammatory bowel disease inflammatory skin conditions intravascular catheter isoflavones Kampo formulae knee osteoarthritis LI-RADS lip swelling liver cancer loss of infectivity LPS macrophage medical dermatology meta-analysis modulation mucogingivitis multivariate analysis olaparib orofacial granulomatosis osteoclast pancreatic adenocarcinoma pancreatic cancer PARP pharmacological activities phosphorylated extracellular signal-regulated kinase (pERK) phytochemicals pine cone extract povidone-iodine preoperative anxiety protease protocol Pterospartum tridentatum qigong QSAR analysis quercetin randomized controlled trial randomized controlled trials RANKL rat remote monitoring renal cell cancer respiratory function Roussel Uclaf Causality Assessment Method RUCAM rucaparib rutin sarcoidosis solubilization method Stachys L. superior vena cava syndrome systematic review tag-like lesions Tai Chi targeted therapy telemedicine Th1/Th2 cytokine balance TLR4 traditional medicine traditional uses transient receptor potential ankyrin 1 (TRPA1) channel TREM2 tumor evolution tumor heterogeneity tumor specificity ulcerative colitis ultra-performance liquid chromatography venous thrombosis villosin whole-cell patch-clamp recording Yokukansan |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910576874503321 |
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Sakagami Hiroshi
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| MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Structural, Magnetic, Dielectric, Electrical, Optical and Thermal Properties of Nanocrystalline Materials: Synthesis, Characterization and Application
| Structural, Magnetic, Dielectric, Electrical, Optical and Thermal Properties of Nanocrystalline Materials: Synthesis, Characterization and Application |
| Autore | Yadav Raghvendra Singh |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 online resource (197 p.) |
| Soggetto topico | Technology: general issues |
| Soggetto non controllato |
2D material
Ag@Au nanoparticle analytical solution Au-ZnO/C2H6O2 beryllium oxide chemical vapor transport core-shell structure crystal growth dielectric constants dielectric properties electromagnetic electronic materials ellipsometry entropy generation error analysis Fano resonances fentanyl glucose graphene quantum dots heat transfer high-accuracy measurement hybrid nanofluid lithium Niobate low dimensional magnetism magnetic chains metamaterials MHD mixed convection nanocrystalline cellulose nanoparticle nucleation non-linear radiation optical optical metrology photocatalytic activity porous media powder X-ray diffraction radiation effect rietveld refinement rotating systems SAW devices sea-urchin-like structure sensing SERS shooting method similarity solution slender body revolution sparking process spectroscopy SQUID stability analysis surface energy surface plasmon resonance thin film three-stage Lobatto III-A formula time-dependent flow transition metal phosphorus sulfide triple solutions van der Waals layered material vapor deposition α-Fe2O3 γ-alumina nanoparticle |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | Structural, Magnetic, Dielectric, Electrical, Optical and Thermal Properties of Nanocrystalline Materials |
| Record Nr. | UNINA-9910557621303321 |
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Yadav Raghvendra Singh
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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