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A Personalized Medicine Approach to the Diagnosis and Management of Autism Spectrum Disorder
| A Personalized Medicine Approach to the Diagnosis and Management of Autism Spectrum Disorder |
| Autore | Frye Richard E |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 online resource (416 p.) |
| Soggetto topico |
Medicine and Nursing
Neurosciences |
| Soggetto non controllato |
acyl-carnitines
ADHD amygdala anxiety Array-Comparative Genomic Hybridization (Array-CGH) ASD associated risk autism autism spectrum disorder autism spectrum disorder (ASD) autism spectrum disorders autonomic disorder B12 biomarker brain brain development cerebral folate deficiency children chromosomal microarray analysis clinical decision support tool clinical utility cobalamin concomitant condition copy number variants cortisol COVID-19 cytokines digital biomarkers disorder Ehlers-Danlos syndrome energy metabolism epigenetics fatty acid oxidation fecal metabolites females fetal development Fisher Discriminant Analysis flavonoids folate receptor alpha folate receptor alpha autoantibodies folates folinic acid gastrointestinal symptoms genetic testing genomics glutathione heart rate variability hypermobility spectrum disorders immune dysfunction immunoglobulin G inflammation integrative intervention intravenous immunoglobulin leucovorin locked-in network syndrome logistic regression analysis luteolin mast cell activation syndrome mast cells medical claims metabolomics methylation methylcobalamin microbiome microglia minerals mitochondria model monoamine neurotransmitters n/a network connectivity neuromodulation neurostimulation neurotransmitter deficiency non-linear complex dynamics nutraceuticals OCD omics oxidative stress PANDAS parents patient stratification personalized treatment strategy polygenic risk scores precision medicine pregnancy prenatal environment proteomics quality of life redox metabolism resting-state functional magnetic resonance imaging resveratrol retrospective analysis SARS-CoV-2 single nucleotide polymorphisms sleep anxiety social dyads socio-motor parameters stochastic analysis stress survey systematic review Temple Grandin temporal lobe epilepsy time series analysis transcriptomics transdermal electrical neuromodulation vitamins wearables whole exome sequencing whole genome sequencing α-amylase |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910595075503321 |
Frye Richard E
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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AMP-Activated Protein Kinase Signalling
| AMP-Activated Protein Kinase Signalling |
| Autore | Neumann Dietbert |
| Pubbl/distr/stampa | MDPI - Multidisciplinary Digital Publishing Institute, 2019 |
| Descrizione fisica | 1 online resource (452 p.) |
| Soggetto topico | Biology, life sciences |
| Soggetto non controllato |
?-linker
?RIM 2-methoxyestradiol 3T3-L1 A769662 acetyl-CoA activation loop adaptive thermogenesis adenosine monophosphate-activated protein kinase adherent junctions adipocyte adipose tissue AICAR AID Akt AML AMP-activated protein kinase AMP-activated protein kinase (AMPK) AMPK AMPK kinase AS160 assisted reproduction techniques atrophy autophagy beiging CaMKK2 carrier catechol-O-methyltransferase CBS cellular energy sensing chromatin remodeling CML CMML co-expression CREB developmental origins of health and disease (DOHaD) dietary fatty acids differentiation DNA methylation endothelial cells endothelial function endothelial nitric-oxide synthase energy deficiency energy metabolism energy utilization epigenetics epithelial cells exercise fatty acid oxidation fiber-type food intake gestational diabetes mellitus glucose uptake glycogen glycogen storage disease HDAC4/5 HDACs heat shock protein hepatocyte hindlimb suspension histone modification host defense hypertension hypertrophy hypothalamus IL-1? Immediate early genes indirect calorimetry infection insulin signalling ionomycin KATs kidney disease lipid metabolism liver LKB1 macrophages MDCK MDS mechanical unloading medulloblastoma membrane membranes metabolic disease metabolic-inflammation metabolism microarrays mitochondria monocytes motility motor endplate remodeling mTOR mycobacteria MyHC I(?) n/a NAD+ nectin-afadin NLRP3 nutrient-sensing signals nutrigenomics nutrition oxidative stress p70S6K par complex peroxisome proliferator-activated receptor gamma coactivator 1-? (PGC1?) phenylephrine phosphorylation PKA preeclampsia pregnancy proteasome protein acetylation protein kinase B protein synthesis pump regrowth renin-angiotensin system resveratrol signaling sirtuin 1 (SIRT1) skeletal muscle soleus muscle soluble Adenylyl cyclase sonic hedgehog spermatozoa steatosis stress synaptic activation TAK1 TBC1D4 tight junctions transcription transporter ULK vasoconstriction vasodilation ZO-1 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910346858503321 |
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Neumann Dietbert
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| MDPI - Multidisciplinary Digital Publishing Institute, 2019 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Edible Insects as Innovative Foods : Nutritional, Functional and Acceptability Assessments
| Edible Insects as Innovative Foods : Nutritional, Functional and Acceptability Assessments |
| Autore | Jung Chuleui |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 |
| Descrizione fisica | 1 online resource (335 p.) |
| Soggetto topico | Technology: general issues |
| Soggetto non controllato |
acceptance
Acheta domesticus Africa Alcalase alcoholic fatty liver alternative food resource Amino acids Antheraea assamensis antimicrobial antioxidant antioxidant activities antioxidant activity Apis cerana indica attitude avoid bio-active compounds biodiversity bioresource blood coagulation characteristics consumer analysis culture defatted powder degree of hydrolysis disgust DRSA edible insect edible insects emotions Enterococcus entomophagy enzymatic hydrolysis ethanol fatty acid oxidation fatty acids feed supplementation food food choice food hygiene food law food policy food safety food shortage food/feed safety growth performance haemolysis honey insect insect edibility insect powders insects lipogenesis mealworm mealworm oil minerals mirror neurons model system Nagaland neophobia novel food novel proteins nutrient composition nutrients nutrition platelet aggregation preparation processed processing protein hydrolysate psychology Samia cynthia ricini sensory shelf life silkworm silkworm powder sociolinguistics Sprague-Dawley rats steamed and freeze-dried mature silkworm larval powder supplement sustainable food techno-functional properties Teleogryllus emma Tenebrio molitor thermal processing traditional knowledge Vespa mandarinia Vespa velutina nigrithorax Vespula orbata wasp larva willingness to eat yellow mealworm |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | Edible Insects as Innovative Foods |
| Record Nr. | UNINA-9910557113703321 |
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Jung Chuleui
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Impaired Mitochondrial Bioenergetics under Pathological Conditions
| Impaired Mitochondrial Bioenergetics under Pathological Conditions |
| Autore | Lenaz Giorgio |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 online resource (460 p.) |
| Soggetto topico |
Biochemistry
Biology, life sciences Research & information: general |
| Soggetto non controllato |
aging
aging heart assembly factor ATP synthase ATP synthase/hydrolase atypical myopathy Barth syndrome Bcl-2 family bioenergetics C cancer cardiolipin cardiomyopathy cell culture cell signaling cellular bioenergetics cellular signaling complex I assembly complex I deficiency complex I structure complex III COVID-19 cristae cytochrome b diabetes Dilated Cardiomyopathy with Ataxia electron transport chain energy metabolism entorhinal cortex equine primary myoblasts exercise fatty acid oxidation fibroblasts frozen tissue G mutation glucagon heart failure high-resolution respirometry human disease immune system influenza innate immune response insulin Leigh syndrome leukocytes lipoxidation-derived damage m.3243A> m.8909T> mammalian complex I mathematical model MAVS MDA5 metabolic disease mitochondria mitochondrial disease mitochondrial diseases mitochondrial DNA mitochondrial dynamic mitochondrial dynamics mitochondrial dysfunction mitochondrial permeability transition pore mitochondrial proteostasis MT-ATP6 MTCYB mutations n/a NADH dehydrogenase nephropathy neurodegeneration oleate oxidative damage oxidative phosphorylation oxidative stress oxygen consumption palmitate pancreatic endocrine cells pet mutants platelets programmed cell death protein import respiratory chain respiratory complex assembly respiratory complexes respiratory supercomplexes respirometry RIG-I ROS RSV Saccharomyces cerevisiae SARS CoV-2 Sengers syndrome skeletal muscle supercomplexes supernumerary subunits toxicity assays viral infections yeast |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910585934503321 |
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Lenaz Giorgio
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Mitochondria in Health and Diseases
| Mitochondria in Health and Diseases |
| Autore | Javadov Sabzali |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 |
| Descrizione fisica | 1 online resource (434 p.) |
| Soggetto topico | Medicine and Nursing |
| Soggetto non controllato |
2-oxoglutarate dehydrogenase
4-HNE adenine nucleotide translocase ADP/ATP carrier aging amino acid neurotransmitter ancient mutation antioxidant system antioxidants apoptosis BAX BCL-2 BKCa channels cardiolipin cardiomyocytes cardioprotection cerebellar amino acid metabolism cholangiocellular carcinoma colon complex I (CI) deficiency cyclosporin A cytoskeletal proteins DDE dentate granule cell development dextran DRP1 dsRNA electron and confocal microscopy electron tunneling (ET) energy metabolism epilepsy ERK1/2 ETC complexes fatty acid oxidation ferritin gemfibrozil GW9662 H9c2 cardiomyoblasts healthy cells heart hepatic fibrogenesis hepcidin high-fat diet hippocampus HtrA2/Omi human amniotic membrane human diseases hyperforin hypoglycemia hypoxia inflammation innate immunity inorganic phosphate interferon response intranuclear mitochondria ion homeostasis iron overload ischemia reperfusion injury JNK KmADP Langendorff LHON life span lipid droplet lipid handling liver LONP1 metabolome and proteome profiling mitochondria mitochondria bioenergetics mitochondria calcium buffering mitochondria permeability transition pore mitochondria: energy metabolism mitochondrial cell death mitochondrial connexin 43 mitochondrial dynamics mitochondrial dysfunction mitochondrial function mitochondrial gene expression mitochondrial homeostasis mitochondrial interactions mitochondrial permeability transition pores mitochondrial UCP2 morphology mtDNA mtDNA transcription mtRNA muscle aging myocardial neuron death neuroprotection oxidative phosphorylation oxidative stress perilipin 5 physical performance pilocarpine pioglitazone PKA plectin post-transcriptional mtRNA processing potassium channel pravastatin protein phosphatases pyruvate dehydrogenase pyruvate dehydrogenase kinase reactive oxygen species reactive oxygen species (ROS) reactive oxygen species stress redox state regeneration respirasome assembly respiratory supercomplexes ROS rosiglitazone seizure Siberian population signaling signaling pathways siRNA sodium dichloroacetate specific genetic background telomerase activity telomere length tensile strength transferrin tricarboxylic acid cycle tubulin beta TUNEL TZD uncoupling uncoupling protein ZIP |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557577203321 |
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Javadov Sabzali
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Novel Natural-based Biomolecules Discovery for Tackling Chronic Diseases
| Novel Natural-based Biomolecules Discovery for Tackling Chronic Diseases |
| Autore | Kwok Hang Fai |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 online resource (180 p.) |
| Soggetto topico |
Humanities
Social interaction |
| Soggetto non controllato |
AKT
amphibian Bowman-Birk inhibitor amyloidogenesis anionic lipids anti-inflammation anticancer therapy anticancer therapy/cancer treatment antifungal antioxidant apoptosis Asteraceae Astragalus membranaceus Bcl-2 family proteins binding affinity branched-chain fatty acids cell cycle arrest colorectal cancer Conidiobolus heterosporus COX-2 DAPK1 docetaxel drug delivery system drug design endoplasmic reticulum F23R variant fatty acid oxidation fibroblasts fucoidan G-protein activation gingiva hepatocyte hIAPP iNOS insulin insulin granules kynurenines lignan lipid metabolism lung cancer molecular cloning molecular docking n/a natural-based compound NO orientin PDX-1 peptides peroxisome proliferator-activated receptor α Petasites japonicus PGE2 pharmacophore PI3K PLGA pomegranate post-translational modification PPARγ protease inhibitor protein degradation punicalagin SENP STAT3 SUMO survivin tannins Tat peptide unfolded protein response wound healing β-cell cytotoxicity β-sheet transitions μ-opioid receptor |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557607403321 |
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Kwok Hang Fai
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Nutraceuticals: The New Frontier
| Nutraceuticals: The New Frontier |
| Autore | Santini Antonello |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 |
| Descrizione fisica | 1 online resource (94 p.) |
| Soggetto topico |
Biology, life sciences
Cultural studies: food and society Research and information: general |
| Soggetto non controllato |
adipogenesis
alcohols antioxidant activity antioxidants biophenols Chlorella cinnamon cladodes EVOO fatty acid oxidation fatty acids food profiling food supplement health HPLC hydroxytyrosol Klamath lipogenesis lovastatin microalgae multivariate statistical analysis n/a nutraceutical oleuropein OPLS-DA Opuntia ficus-indica polyphenols pumpkin seed oil quality control red yeast rice safety Spirulina stereospecific analysis sterols trans-resveratrol white adipocyte differentiation wine β-polysaccharides |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | Nutraceuticals |
| Record Nr. | UNINA-9910557735003321 |
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Santini Antonello
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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PPARs as Key Mediators of Metabolic and Inflammatory Regulation
| PPARs as Key Mediators of Metabolic and Inflammatory Regulation |
| Autore | Vázquez-Carrera Manuel |
| Pubbl/distr/stampa | MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 online resource (456 p.) |
| Soggetto topico |
Biochemistry
Biology, life sciences Research and information: general |
| Soggetto non controllato |
adipose tissue
AMPK amygdala atopic dermatitis bezafibrate brain browning cancer common carotid artery occlusion coregulator corticotropin releasing hormone coumarin crystal structure cytomegalovirus dairy animals depression diabetes DNA methylation docking doping control dual/pan agonist electroretinography ELISA energy homeostasis exercise fatty acid oxidation fatty acids fenofibrate fenofibric acid fibroblast growth factor 21 fluorescent ligand GDF15 gene transcription glucose GSK3787 GW0742 hepatic damage hepatic sex-biased gene expression histone modification HIV immunity immunohistochemistry infection inflammation insulin resistance kidney fibrosis ligand lipid droplets lipid metabolism lipidomics lipopolysaccharide (LPS) liver damage lung M. leprae M. tuberculosis metabolic alterations metabolic reprograming metabolic syndrome microglia micronutrients miRNA molecular docking mycobacteria n/a neural stem cells neurogenesis neuroinflammation neuropathology nitric oxide synthase non-alcoholic fatty liver disease (NAFLD) non-alcoholic steatohepatitis (NASH) nonalcoholic fatty liver disease (NAFLD) norepinephrine nuclear factors nuclear receptor nuclear receptors nucleus accumbens nutrigenomics obesity oleoylethanolamide P2Y2 receptor palmitoylethanolamide pattern-recognition receptors pemafibrate peroxisome peroxisome proliferator-activated receptor peroxisome proliferator-activated receptor alpha peroxisome proliferator-activated receptor gamma (PPARγ) peroxisome proliferator-activated receptors (PPAR) peroxisome-proliferator-activated receptor phagocytosis pharmacological targets PPAR PPAR gamma PPARg PPARs PPARα PPARα knockout PPARβ/δ PPARγ PPARγ ligand PPRE proliferation psoriasis pulmonary arterial hypertension pulmonary artery quercetin real-time PCR regulatory T cells resveratrol retinal ischemia screening sex dimorphism signaling pathway skeletal muscle subgenual prefrontal cortex substrate metabolism TGFβ toll-like receptor 4 type 2 diabetes mellitus vascular injury X-ray crystallography Zika β-oxidation |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910576873703321 |
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Vázquez-Carrera Manuel
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| MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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The metabolic challenges of immune cells in health and disease
| The metabolic challenges of immune cells in health and disease |
| Autore | Christian Frezza |
| Pubbl/distr/stampa | Frontiers Media SA, 2015 |
| Descrizione fisica | 1 online resource (80 p.) |
| Collana | Frontiers Research Topics |
| Soggetto topico | Medicine and Nursing |
| Soggetto non controllato |
fatty acid oxidation
Glycolysis Immunometabolism Inflammation lymphocyte macrophage metabolic syndrome Obesity Pentose Phosphate Pathway TCA cycle |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910137091503321 |
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Christian Frezza
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| Frontiers Media SA, 2015 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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