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Brain Injury and Neurodegeneration: Molecular, Functional, and Translational Approach
| Brain Injury and Neurodegeneration: Molecular, Functional, and Translational Approach |
| Pubbl/distr/stampa | MDPI - Multidisciplinary Digital Publishing Institute, 2023 |
| Descrizione fisica | 1 online resource (428 p.) |
| Soggetto topico |
Medicine and Nursing
Neurology and clinical neurophysiology |
| Soggetto non controllato |
18F-FDG PET
AGTPBP1 Alzheimer's disease amyloid beta anosmia anti-convulsants anti-epileptic drugs apoptosis blunt-force TBI brain injury CCP1 chronic alcoholism cognitive impairment CONDCA COVID-19 drug targets edema epigenetics epileptogenesis excitotoxicity exomiRNA exosome extracellular matrix FABP3 FABP5 FABP7 gene regulation GSK-3β HHV-6 histone deacetylase histone deacetylase inhibitor hypoxia hypoxic-ischemic injuries icariin icaritin inflammation ischemia ischemic stroke isomiR mechanical stimulations microglia microRNA middle cerebral artery occlusion mild traumatic brain injury miRNA mitochondria moderate traumatic brain injury mPGES-1 n/a natural products neural ischemia neural mitochondrial functions neural tissue hypoxic injuries neuraxis neuro-recovery neurodegeneration neurodegenerative diseases neuroinflammation neurons neuroprotection neurorehabilitation neurotrauma NNA1 non-communicable disease olfactory dysfunction organelle dysfunction oxidative stress p-Tau Parkinson's disease pcd PGE2 phytochemicals post-traumatic seizures pseudo-resistance purmorphamine reactive oxygen species RNAseq SARS-CoV-2 seizures sonic hedgehog signaling stretching Substantia Nigra TBI therapeutic strategies transcriptional modifications traumatic brain injury traumatic brain injury (TBI) treadmill exercise tRNA zebrafish |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | Brain Injury and Neurodegeneration |
| Record Nr. | UNINA-9910743275703321 |
| MDPI - Multidisciplinary Digital Publishing Institute, 2023 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Metabolomics in Neurodegenerative Disease
| Metabolomics in Neurodegenerative Disease |
| Autore | Green Brian |
| Pubbl/distr/stampa | MDPI - Multidisciplinary Digital Publishing Institute, 2020 |
| Descrizione fisica | 1 online resource (184 p.) |
| Soggetto topico | Biology, life sciences |
| Soggetto non controllato |
?-synuclein aggregates
13C-labeled succinate 1H NMR 6-OHDA age-related macular degeneration Alzheimer's disease bile acids biomarkers C. elegans cerebral ischemia cerebral palsy dementia with Lewy bodies direct mass spectrometry drusen endothelin-1 energy metabolism excitotoxicity fatty acid fatty acid metabolism GC-MS glutamic acid imaging mass spectrometry LC-MS lipidomics malonate mass spectrometry metabolic pathways metabolism metabolomics micro-dialysis midbrain mitochondrial dysfunction myo-inositol n/a natural product neurodegeneration Parkinson's disease Parkinson's disease dementia pathogenesis plasma prodromal Parkinson's disease reperfusion retinal pigment epithelium Streptomyces venezuelae subacute mild traumatic brain injury targeted mass spectrometry tricarboxylic acid cycle |
| ISBN | 3-03928-041-4 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910404087203321 |
Green Brian
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| MDPI - Multidisciplinary Digital Publishing Institute, 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Metabotropic Glutamate Receptors and Neurological/Psychiatric Disorders
| Metabotropic Glutamate Receptors and Neurological/Psychiatric Disorders |
| Autore | Palazzo Enza |
| Pubbl/distr/stampa | Frontiers Media SA, 2019 |
| Descrizione fisica | 1 online resource (139 p.) |
| Soggetto topico |
Neurosciences
Science: general issues |
| Soggetto non controllato |
excitotoxicity
metabotropic glutamate receptors negative allosteric modulators Neurogenesis Neuroinflammation neurological disorders Neuroprotection Positive allosteric modulators psychiatric disorders |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557689303321 |
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Palazzo Enza
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| Frontiers Media SA, 2019 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Neuroprotection: Rescue from Neuronal Death in the Brain
| Neuroprotection: Rescue from Neuronal Death in the Brain |
| Autore | Lee Bae Hwan |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 online resource (408 p.) |
| Soggetto topico | Research & information: general |
| Soggetto non controllato |
acid-sensing ion channels
adenoviral vector adiponectin aging Alzheimer's disease amiloride amyloid-beta amyotrophic lateral sclerosis antioxidant antioxidants apoptosis ascorbic acid astrocytes astrocytic networks axotomy BDNF bean phosphatidylserine (Bean-PS) blood brain barrier brain brain targeting brain-derived neurotrophic factor calcium activity catecholamines cation-chloride cotransporters cell death choline acetyltransferase (ChAT) connexin 43 cortisol CRISPR/cas9 depression electroneutral transport endotheline-1 excitotoxicity GDNF gerbil glia glioblastoma global cerebral ischemia GPR4 receptor hippocampus homocysteine human umbilical cord blood mononuclear cells inflammation insulin ischemia ischemic stroke KCCs lactate lipid emulsion liver growth factor MEK/ERK metabolic disease microglia middle cerebral artery occlusion miRNAs moderate hypoxia motoneurons MPP+ N-acetyl-l-cysteine n/a nanoparticle-based drug delivery NCAM neural injury neurodegeneration neurodegenerative disease neurodegenerative disorder neurogenesis neuronal death neuroprotection nimodipine nitrite NKCCs oculomotor system organotypic hippocampal slice culture oxidative stress oxygen-glucose deprivation Parkinson's disease PGC-1α physical exercise PI3K/AKT preventive gene therapy psychomotor function pyridoxine deficiency reaction time reperfusion injury sodium-hydrogen exchanger-1 status epilepticus stroke subarachnoid haemorrhage synaptic plasticity Tg2576 transgenic mice transient receptor potential melastatin 2 trimethyltin (TMT) trophic factors vascular endothelial growth factor vascular endothelial growth factor receptor 2 VEGF WNK-SPAK/OSR1 zinc |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | Neuroprotection |
| Record Nr. | UNINA-9910557716703321 |
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Lee Bae Hwan
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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The Role of Mitochondria, Oxidative Stress and Altered Calcium Homeostasis in Amyotrophic Lateral Sclerosis: From Current Developments in the Laboratory to Clinical Treatments
| The Role of Mitochondria, Oxidative Stress and Altered Calcium Homeostasis in Amyotrophic Lateral Sclerosis: From Current Developments in the Laboratory to Clinical Treatments |
| Autore | Manoj Kumar Jaiswal |
| Pubbl/distr/stampa | Frontiers Media SA, 2017 |
| Descrizione fisica | 1 online resource (336 p.) |
| Collana | Frontiers Research Topics |
| Soggetto topico | Neurosciences |
| Soggetto non controllato |
Amyotrophic lateral sclerosis (ALS)
Ca2+ signaling excitotoxicity Mitochondria Motor neuron disease (MND) multidrug therapy multifactorial disease neurodegenerative disease Riluzole Superoxide dismutase 1 (SOD1) |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | Role of Mitochondria, Oxidative Stress and Altered Calcium Homeostasis in Amyotrophic Lateral Sclerosis |
| Record Nr. | UNINA-9910220056703321 |
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Manoj Kumar Jaiswal
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| Frontiers Media SA, 2017 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Understanding Neuromuscular Health and Disease: Advances in Genetics, Omics, and Molecular Function
| Understanding Neuromuscular Health and Disease: Advances in Genetics, Omics, and Molecular Function |
| Autore | Duddy William |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 online resource (318 p.) |
| Soggetto topico | Research & information: general |
| Soggetto non controllato |
-omics approaches
AAV adult patients ALS ALS genes ALS pathology ALS variants Amyotrophic Lateral Sclerosis autophagy axonal transport Becker muscular dystrophy becker muscular dystrophy (BMD) biomarkers calprotectin Canadian Neuromuscular Disease Registry clinical trials comparative genomic hybridization array (CGH) corticosteroids CRISPR-Cas9 D4Z4 deflazacort disease heterogeneity disease models disease modifiers DMARD DMD Duchenne muscular dystrophy duchenne muscular dystrophy (DMD) Duchenne muscular dystrophy (DMD) DUX4 dystrophin dystrophinopathy dystrophy Emery-Dreifuss muscular dystrophy endocytosis epigenetic changes eteplirsen excitotoxicity exon skipping exon skipping therapy exon-skipping therapies facioscapulohumeral dystrophy FSHD functional outcomes gene editing gene prioritization gene therapy genetic neuromuscular disorders genome-wide association studies genomics genotype-phenotype genotype-phenotype correlations glucocorticoids golodirsen GWAS LMNA machine learning methotrexate miRNA mitochondria dysfunction MND multiple logistic regression analysis multiplex ligation probe amplification (MLPA) multiplex polymerase chain reaction (PCR) muscle n/a neuromuscular diseases next-generation sequencing (NGS) Nusinersen Omics oxidative stress pharmacodynamic biomarkers pharmacogenomics polyadenylation precision medicine prednisone proteomics reading frame rule regulation rheumatoid arthritis RNA metabolism safety Sanger sequencing secretion skip-equivalent deletions SMA SNP spinal muscular atrophy TALEN toxicity transcription translational research viltolarsen XLMTM |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | Understanding Neuromuscular Health and Disease |
| Record Nr. | UNINA-9910557669103321 |
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Duddy William
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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