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Metabolomics in Neurodegenerative Disease
| Metabolomics in Neurodegenerative Disease |
| Autore | Green Brian |
| Pubbl/distr/stampa | MDPI - Multidisciplinary Digital Publishing Institute, 2020 |
| Descrizione fisica | 1 electronic resource (184 p.) |
| Soggetto non controllato |
glutamic acid
direct mass spectrometry neurodegeneration 6-OHDA targeted mass spectrometry mitochondrial dysfunction myo-inositol metabolomics bile acids subacute mild traumatic brain injury age-related macular degeneration metabolic pathways energy metabolism midbrain Alzheimer's disease biomarkers 1H NMR Parkinson's disease dementia GC-MS pathogenesis tricarboxylic acid cycle micro-dialysis 13C-labeled succinate metabolism lipidomics dementia with Lewy bodies fatty acid prodromal Parkinson's disease malonate cerebral ischemia mass spectrometry retinal pigment epithelium excitotoxicity endothelin-1 reperfusion C. elegans Streptomyces venezuelae ?-synuclein aggregates natural product fatty acid metabolism imaging mass spectrometry LC-MS drusen cerebral palsy plasma Parkinson's disease |
| ISBN | 3-03928-041-4 |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910404087203321 |
Green Brian
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| MDPI - Multidisciplinary Digital Publishing Institute, 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Metabotropic Glutamate Receptors and Neurological/Psychiatric Disorders
| Metabotropic Glutamate Receptors and Neurological/Psychiatric Disorders |
| Autore | Palazzo Enza |
| Pubbl/distr/stampa | Frontiers Media SA, 2019 |
| Descrizione fisica | 1 electronic resource (139 p.) |
| Soggetto topico |
Science: general issues
Neurosciences |
| Soggetto non controllato |
metabotropic glutamate receptors
neurological disorders psychiatric disorders Neuroprotection Neuroinflammation excitotoxicity Neurogenesis Positive allosteric modulators negative allosteric modulators |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557689303321 |
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Palazzo Enza
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| Frontiers Media SA, 2019 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Neuroprotection: Rescue from Neuronal Death in the Brain
| Neuroprotection: Rescue from Neuronal Death in the Brain |
| Autore | Lee Bae Hwan |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 electronic resource (408 p.) |
| Soggetto topico | Research & information: general |
| Soggetto non controllato |
global cerebral ischemia
amiloride sodium-hydrogen exchanger-1 zinc neuronal death neuroprotection neurodegenerative disorder choline acetyltransferase (ChAT) trimethyltin (TMT) bean phosphatidylserine (Bean-PS) brain-derived neurotrophic factor moderate hypoxia physical exercise psychomotor function reaction time cortisol catecholamines nitrite endotheline-1 lactate pyridoxine deficiency ischemia gerbil homocysteine cell death glia neurogenesis N-acetyl-l-cysteine transient receptor potential melastatin 2 neurodegeneration Alzheimer's disease metabolic disease adiponectin insulin antioxidants stroke preventive gene therapy adenoviral vector VEGF GDNF NCAM human umbilical cord blood mononuclear cells antioxidant brain neurodegenerative disease oxidative stress PGC-1α vascular endothelial growth factor vascular endothelial growth factor receptor 2 PI3K/AKT MEK/ERK status epilepticus hippocampus middle cerebral artery occlusion reperfusion injury lipid emulsion excitotoxicity apoptosis GPR4 receptor MPP+ Parkinson's disease CRISPR/cas9 ischemic stroke blood brain barrier nanoparticle-based drug delivery brain targeting BDNF miRNAs synaptic plasticity depression glioblastoma astrocytes astrocytic networks connexin 43 calcium activity neural injury nimodipine subarachnoid haemorrhage acid-sensing ion channels oxygen-glucose deprivation liver growth factor inflammation microglia Tg2576 transgenic mice amyloid-beta oculomotor system trophic factors motoneurons axotomy amyotrophic lateral sclerosis electroneutral transport cation-chloride cotransporters KCCs NKCCs WNK-SPAK/OSR1 ascorbic acid aging organotypic hippocampal slice culture |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | Neuroprotection |
| Record Nr. | UNINA-9910557716703321 |
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Lee Bae Hwan
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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The Role of Mitochondria, Oxidative Stress and Altered Calcium Homeostasis in Amyotrophic Lateral Sclerosis: From Current Developments in the Laboratory to Clinical Treatments
| The Role of Mitochondria, Oxidative Stress and Altered Calcium Homeostasis in Amyotrophic Lateral Sclerosis: From Current Developments in the Laboratory to Clinical Treatments |
| Autore | Manoj Kumar Jaiswal |
| Pubbl/distr/stampa | Frontiers Media SA, 2017 |
| Descrizione fisica | 1 electronic resource (336 p.) |
| Collana | Frontiers Research Topics |
| Soggetto non controllato |
Mitochondria
neurodegenerative disease Ca2+ signaling multidrug therapy Amyotrophic lateral sclerosis (ALS) Superoxide dismutase 1 (SOD1) Motor neuron disease (MND) excitotoxicity Riluzole multifactorial disease |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | Role of Mitochondria, Oxidative Stress and Altered Calcium Homeostasis in Amyotrophic Lateral Sclerosis |
| Record Nr. | UNINA-9910220056703321 |
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Manoj Kumar Jaiswal
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| Frontiers Media SA, 2017 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Understanding Neuromuscular Health and Disease: Advances in Genetics, Omics, and Molecular Function
| Understanding Neuromuscular Health and Disease: Advances in Genetics, Omics, and Molecular Function |
| Autore | Duddy William |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 electronic resource (318 p.) |
| Soggetto topico | Research & information: general |
| Soggetto non controllato |
LMNA
Emery-Dreifuss muscular dystrophy Omics ALS MND ALS variants genotype-phenotype ALS genes FSHD DUX4 transcription muscle regulation spinal muscular atrophy adult patients disease heterogeneity Nusinersen disease modifiers functional outcomes biomarkers epigenetic changes -omics approaches oxidative stress mitochondria dysfunction axonal transport autophagy endocytosis secretion excitotoxicity RNA metabolism Duchenne muscular dystrophy (DMD) exon-skipping therapies next-generation sequencing (NGS) Sanger sequencing multiplex ligation probe amplification (MLPA) multiplex polymerase chain reaction (PCR) comparative genomic hybridization array (CGH) viltolarsen eteplirsen golodirsen rheumatoid arthritis SNP DMARD methotrexate pharmacogenomics Duchenne muscular dystrophy pharmacodynamic biomarkers prednisone deflazacort glucocorticoids corticosteroids safety neuromuscular diseases translational research disease models precision medicine miRNA proteomics calprotectin dystrophy Becker muscular dystrophy dystrophinopathy genotype-phenotype correlations Canadian Neuromuscular Disease Registry reading frame rule dystrophin multiple logistic regression analysis exon skipping therapy Amyotrophic Lateral Sclerosis machine learning genome-wide association studies GWAS genomics ALS pathology gene prioritization AAV genetic neuromuscular disorders gene therapy clinical trials toxicity SMA DMD XLMTM facioscapulohumeral dystrophy TALEN CRISPR-Cas9 gene editing polyadenylation D4Z4 duchenne muscular dystrophy (DMD) becker muscular dystrophy (BMD) exon skipping skip-equivalent deletions |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | Understanding Neuromuscular Health and Disease |
| Record Nr. | UNINA-9910557669103321 |
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Duddy William
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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