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ABC Transporters in Human Diseases
| ABC Transporters in Human Diseases |
| Autore | Falguières Thomas |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 online resource (494 p.) |
| Soggetto topico |
Biology, life sciences
Research & information: general |
| Soggetto non controllato |
5' untranslated region
AAV ABC ABC (ATP-binding cassette) transporters ABC transporter ABC transporters ABCA subfamily ABCA7 ABCB1 ABCB11 ABCB4 ABCC2 ABCC6 ABCG2 ABCG2 genotype ABCG5 ABCG5/G8 ABCG8 adrenoleukodystrophy Alzheimer's disease amyloid-beta anticancer antifungal resistance atherosclerosis ATP-binding cassette transporter ATP-binding cassette transporter A1 (ABCA1) Aβ peptides BCRP beta-amyloid bile salts bile secretion bioinformatics blood-brain barrier breast cancer BRIC BSEP calcification cAMP cancer cellular ATP efflux chaperones cholesterol cholesterol homeostasis cis-acting elements clinico-genetic analysis competitive allele-specific PCR disease-free survival drug action drug transport dyslipidemia early-onset gout erlotinib ethnic specificity fatty acids functional divergence gall stone gene therapy generalized arterial calcification of infancy genetic variations gout HDL-C homology modeling hyperuricemia intracellular traffic intrahepatic cholestasis invasion MDR3 mechanism mechanism of action membrane protein microparticles migration molecular partners MRP1 MRP4 multidrug resistance multidrug transporter mutagenesis mutations n/a neuron next-generation sequencing NT5E P-glycoprotein peroxisome PET PFIC PFIC2 phagocytosis phosphatidylcholine phytosterol polar relay polymorphisms precision medicine proliferation pseudoxanthoma elasticum Pseudoxanthoma elasticum (PXE) pyrophosphate RAB GTPase rare variant regulatory extension regulatory insertion reverse cholesterol transport Roma serum uric acid single nucleotide polymorphism sitosterolemia SK-N-SH SNP SUA-lowering therapy substrate-binding site tariquidar taxol therapies therapy response TNAP trafficking transport transporter type 2 diabetes urate urate transporter uric acid xenosterol yeast |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910674029103321 |
Falguières Thomas
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Application of Bioinformatics in Cancers
| Application of Bioinformatics in Cancers |
| Autore | Brenner J. Chad |
| Pubbl/distr/stampa | MDPI - Multidisciplinary Digital Publishing Institute, 2019 |
| Descrizione fisica | 1 online resource (418 p.) |
| Soggetto topico | Biotechnology |
| Soggetto non controllato |
activation induced deaminase
AID/APOBEC alternative splicing anti-cancer artificial intelligence bioinformatics Bioinformatics tool biomarker discovery biomarker signature biomarkers biostatistics brain brain metastases breast cancer breast cancer detection breast cancer prognosis Bufadienolide-like chemicals cancer cancer biomarker cancer biomarkers cancer CRISPR cancer modeling cancer prognosis cancer treatment cancer-related pathways cell-free DNA chemotherapy circulating tumor DNA (ctDNA) classification clinical/environmental factors colorectal cancer comorbidity score Computational Immunology concatenated deep feature copy number aberration copy number variation curation curative surgery datasets decision support systems deep learning denoising autoencoders differential gene expression analysis diseases genes DNA DNA sequence profile drug resistance epigenetics erlotinib estrogen extreme learning false discovery rate feature extraction and interpretation feature selection firehose functional analysis gefitinib gene expression analysis gene inactivation biomarkers gene loss biomarkers gene signature extraction genomic instability GEO DataSets head and neck cancer health strengthening herb hierarchical clustering analysis high-throughput analysis histopathological imaging histopathological imaging features HNSCC hormone sensitive cancers HP hTERT imaging independent prognostic power interaction intratumor heterogeneity knockoffs KRAS mutation locoregionally advanced machine learning meta-analysis methylation microarray miRNA miRNAs mitochondrial metabolism mixture of normal distributions molecular mechanism molecular subtypes Monte Carlo mortality multiple-biomarkers mutable motif mutation Neoantigen Prediction network analysis Network Analysis network pharmacology network target neurological disorders next generation sequencing observed survival interval omics omics profiles oral cancer ovarian cancer overall survival pancreatic cancer pathophysiology PD-L1 precision medicine predictive model protein R package RNA self-organizing map single-biomarkers single-cell sequencing skin cutaneous melanoma somatic mutation StAR steroidogenic enzymes survival analysis TCGA TCGA mining telomerase telomeres The Cancer Genome Atlas traditional Chinese medicine transcriptional signatures treatment de-escalation tumor tumor infiltrating lymphocytes tumor microenvironment variable selection |
| ISBN | 3-03921-789-5 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910367743403321 |
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Brenner J. Chad
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| MDPI - Multidisciplinary Digital Publishing Institute, 2019 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Cancer Nanomedicine
| Cancer Nanomedicine |
| Autore | Hoskins Clare |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 |
| Descrizione fisica | 1 online resource (510 p.) |
| Soggetto topico | Technology: general issues |
| Soggetto non controllato |
actin
active targeting acute toxicity adsorption albumin albumin nanoparticle albumin nanoparticles anacardic acid angiogenesis anti-cancer anti-metastatic enzyme cancer therapy anti-topoisomerase activity anti-tumor immunity antibody drug conjugate (ADC) anticancer and antibacterial activity antitumor strategy apoptosis ascorbic acid BALB-neuT mice biodistribution biomimetic biomimetic core-shell nanoparticles biomimicry bleeding blood brain barrier brain tumours breast cancer cabazitaxel cancer cancer diagnosis cancer nanomedicine cancer therapy cathepsin D cathepsin L cats cell signaling cellular interaction cellular microenvironment chemico-physical functionalization chemotherapeutics chirality separation clinical status clinical translation collagen colloidal stability colorectal carcinoma combinatorial therapy copper CPMV CSCs cyclodextrins cytotoxicity diagnostics differentiated neuroblastoma dioleoylphosphatidylethanolamine DNA origami docetaxel dogs DOX doxorubicin drug combination drug delivery drug delivery system drug-gene delivery drug-in-cyclodextrin-in-liposome dual-targeting epithelial-to-mesenchymal transition EPR effect erlotinib everolimus exosomes extracellular vesicles FA-DABA-SMA flow folate folate receptor folic receptor alpha glioblastoma glioma gold nanoparticles gold nanorods graphene oxide hepatocellular carcinoma hyaluronic acid hyaluronidase hybrid nanoparticles hyperthermia hyperthermia therapy hypoxia imaging immune modulation immunosuppression immunotherapy Immunotherapy in situ vaccine in vitro in vitro anti-cancer activity integrin intra-arterial chemotherapy intracellular disruption intracranial glioma iron affinity lanthanide metal ligand lipid nanoparticles liposome liposomes loading lung cancer lymphadenectomy magnetic actuation magnetic drug targeting magnetic hyperthermia magnetic nanoparticles magnetic nanowires magnetic silica-coated iron oxide nanochains magnetometer mammary carcinoma mangiferin MDA-MB-231 melanoma membrane-wrapped mesenchymal stem cells (MSCs) Mesoporous silica nanoparticle mesoporous silica nanoparticles metabolism microbubble microfluidic mitoxantrone mixed micelle molecular imaging monoclonal antibodies multicellular tumor spheroids nano-bio interactions nano-engineered MSCs nanobiotechnology nanocarrier nanomedicine nanomedicines nanomicelles nanoparticle nanoparticles nanostructured lipid carrier nanosystems nanotechnology: bioengineering nanotherapeutics NASH near IR hyperspectral imaging NK cell-derived exosomes oncogenes oncogenic proteins organoids organotin orthotopic lung tumor model osteopontin ovarian cancer ovarian carcinomatosis oxidation-sensitive release paclitaxel pancreatic cancer parvifloron D passive targeting PD-L1 PEGylation peptidomimetics pH responsive photodynamic therapy photodynamic therapy article photothermal therapy photothermal treatment plasmonic photothermal therapy plasmonics platelet membrane PLGA poly(hydroxyethyl acrylate-co-allyl methyl sulfide) copolymer polydopamine nanoparticles polymeric nanoconstruct polymeric nanoparticles prostate cancer radiotherapy real-time quantitative polymerase chain reaction (qPCR) remote loading RGD peptide riboflavin secondary structure self-assembly sentinel lymph node dissection shear stress single-walled carbon nanotubes siRNA size SN38 spheroids SPION stimuli-responsive superparamagnetic iron oxide nanoparticles surgery target treatment targeted delivery targeted delivery system targeted drug delivery targeted therapy TAT peptide temoporfin theranostic nanomaterials theranostics therapeutics titanate nanotubes translational medicine triple negative breast cancer tumor microenvironment tumor spheroid disruption tumor targeting tumor vectorization tumour microenvironment tumour targeting ultrasound vectorization VEGF verteporfin viral nanoparticles vitamin B2 VX2 tumor Vδ2 T cells yet reasonably common within the subject discipline zoledronic acid β-cyclodextrin nanosponges |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557114703321 |
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Hoskins Clare
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Mitogen Activated Protein Kinases : Functions in Signal Transduction and Human Diseases
| Mitogen Activated Protein Kinases : Functions in Signal Transduction and Human Diseases |
| Autore | Tikkanen Ritva |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 |
| Descrizione fisica | 1 online resource (276 p.) |
| Soggetto topico |
Biology, life sciences
Research & information: general |
| Soggetto non controllato |
angiogenesis
antimicrobial peptide aortic valve sclerosis aortic valve stenosis apoptosis atherosclerosis bone remodeling bronchopulmonary dysplasia cancer cancer signaling cecropin A cell cycle Compatibility CR cytokines DAPK DOK4 downregulation DUSP1 ERK ERK1/2 erlotinib extracellular signal-regulated kinase 5 (ERK5) extracellular signal-regulated kinases 1/2 FGF-induced signaling FR180204 FRS2 gastric ulcer HPAECs hyperoxia infantile myofibromatosis inflammation JNK JNKs Kv4.2 MAPK MAPK kinetics MAPK/PI3K/Akt signaling pathway MEK/ERK signaling metabolic profiling mitochondria mitochondrial dysfunction mitogen-activated protein kinase pathway (MAPK pathway) mitogen-activated protein kinases (MAPKs) MKK4 MKK7 N-heterocyclic carbene n/a naphthalimide-metal complex conjugates neuro-inflammation neurodegeneration NF-κB osteoclast differentiation oxidative stress p38 p38 MAPK p38 MAPKs p53 Parkinson's disease PC12 cells phosphorylation platelet-derived growth factor receptor porcine intestinal epithelial cell protein kinase inhibitors protein tyrosine phosphatase interacting protein 51 (PTPIP51) protein-protein interaction (PPI) psoriasis PTPN6 Rabdosia inflexa reactive oxygen species receptor tyrosine kinases ROS SIRT1 SIRT2 SR SRC sunitinib T2DM targeted therapy tight junction protein U0126 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | Mitogen Activated Protein Kinases |
| Record Nr. | UNINA-9910557405603321 |
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Tikkanen Ritva
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Pathogenesis and Therapy of Oral Carcinogenesis
| Pathogenesis and Therapy of Oral Carcinogenesis |
| Pubbl/distr/stampa | MDPI - Multidisciplinary Digital Publishing Institute, 2023 |
| Descrizione fisica | 1 online resource (224 p.) |
| Soggetto topico |
Biology, life sciences
Research & information: general |
| Soggetto non controllato |
4 NQO
biomarkers cancer cancer stem cells caveolin-1 CC chemokine ligand 2 CCL2 cell polarization cholesterol cigarette smoke circulating cell-free DNA clinical trial DNA damage E2F2 EGFR epidermal growth factor receptor erlotinib extracellular matrix head and neck head and neck cancer hedgehog pathway HPV HS-173 human human papillomavirus immunocytochemistry immunohistochemistry inflammation integrin αvβ6 lymph node metastases lysyl oxidase margin mast cells MCP-1 MCs meta-analysis migration miR-125b-5p miR-155-3p miR-214-5p molecular imaging mouse model nEGFR nucleophosmin Nutri-Jelly oral cancer oral cavity oral disease oral squamous cell carcinoma oropharyngeal squamous cell carcinoma OSCC p53 pathogenesis PEITC periodontics periodontitis polymorphism PRI-724 prognosis quality of life SOD2 soluble factors squamous cell carcinoma survival synergism systematic review tertiary chemoprevention tissue factor tooth loss: oral cancer trials tumor suppressor tumour urokinase-type plasminogen activator receptor vismodegib Wnt pathway β-catenin |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910743281703321 |
| MDPI - Multidisciplinary Digital Publishing Institute, 2023 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Pathogenesis and Treatment of Chronic Pruritus
| Pathogenesis and Treatment of Chronic Pruritus |
| Autore | Kwatra Shawn G |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 |
| Descrizione fisica | 1 online resource (144 p.) |
| Soggetto topico | Medicine and Nursing |
| Soggetto non controllato |
antidepressant
antihistaminergic aprepitant associations atopic atopic dermatitis cancer Cav3.2 calcium channel cell signaling ceramide children chronic chronic pruritus chronic pruritus of unknown origin comorbidities demographics dermatitis disease burden drug-induced dupilumab EGFR eosinophilic dermatosis of hematologic malignancy epidemiology epidermal growth factor receptor erlotinib gender IL-13 IL-4 inpatient ion channels itch itch in wounds itch management lichen planus lymphoma lymphomatoid papulosis malignancy medical dermatology medication-related mirtazapine mycosis fungoides national inpatient sample neoplasm neurokinin1-receptor neuropathy NK1R nodular prurigo nodularis noradrenergic pathogenesis pediatric pine tar prurigo prurigo nodularis pruritus psoriasis race racial differences refractory RT-PCR serotonergic skin systematic review therapeutic treatment uremic pruritus wounds |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557104703321 |
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Kwatra Shawn G
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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