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Antitumor and Anti-HIV Agents from Natural Products
| Antitumor and Anti-HIV Agents from Natural Products |
| Autore | Nakagawa-Goto Kyoko |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 |
| Descrizione fisica | 1 electronic resource (338 p.) |
| Soggetto topico | Research & information: general |
| Soggetto non controllato |
natural phaeosphaeride A
antitumor activity human tumor cell lines HEF cell line acute toxicity aspidosperma-type monoterpenoid indole alkaloids antiproliferative activity tubulin inhibitor Bousigonia mekongensis ursolic acid DOTA triterpenoids cytotoxicity diterpenoid alkaloids human tumor cells lipojesaconitine delcosine delpheline kobusine pseudokobusine BRAF inhibitor Mentha aquatica var. Kenting Water Mint essential oil chemoprevention two-stage skin carcinogenesis melanoma curcumin analog apoptosis oxidative stress drug–drug interaction tamoxifen taxol cisplatin Artemisia absinthium L. antioxidants total phenolic content melanoma and breast cancer cell line HaCaT cells inflammation breast cancer cell cycle flavonoids reactive oxygen species tumor suppression antiretroviral agents anti-HIV marine metabolites natural products drug development Ivalin Carpesium divaricatum hepatocellular carcinoma mitochondria-mediated apoptosis NF-κB Hernandia nymphaeifolia butanolides lignan glycosides coumarins antiangiogenic cancer natural agents chemistry medicine cancer stem cell cervical cancer pterostilbene resveratrol caffeic acid cancer multidrug resistance P-glycoprotein phenolic acid oxypeucedanin Angelica dahurica antiproliferation G2/M phase cell cycle arrest p53 SK-Hep-1 hepatoma cells allyl isothiocyanate benzyl isothiocyanate sulforaphane phenethyl isothiocyanate bladder cancer quercetin oral squamous cell carcinoma cells metastasis cell cycle arrest epithelial-to-mesenchymal transition matrix metalloproteinase transforming growth factor-β1 β-lapachone |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557504803321 |
Nakagawa-Goto Kyoko
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Cancer Nanomedicine
| Cancer Nanomedicine |
| Autore | Hoskins Clare |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 |
| Descrizione fisica | 1 electronic resource (510 p.) |
| Soggetto topico | Technology: general issues |
| Soggetto non controllato |
antibody drug conjugate (ADC)
PD-L1 tumor spheroid disruption immune modulation doxorubicin graphene oxide adsorption cathepsin D cathepsin L anti-metastatic enzyme cancer therapy nanoparticles targeted delivery system siRNA osteopontin mammary carcinoma mesenchymal stem cells (MSCs) TAT peptide PLGA paclitaxel nano-engineered MSCs orthotopic lung tumor model intracranial glioma immunotherapy CPMV viral nanoparticles in situ vaccine albumin nanoparticles microbubble ultrasound theranostics hepatocellular carcinoma VX2 tumor intra-arterial chemotherapy lung cancer nanomedicine clinical status cancer therapy breast cancer cell signaling active targeting passive targeting EPR effect oncogenes nanoparticle drug delivery ligand tumor targeting biodistribution Mesoporous silica nanoparticle drug delivery system target treatment lanthanide metal hyaluronic acid hyaluronidase drug combination everolimus dual-targeting magnetic nanoparticles monoclonal antibodies nanostructured lipid carrier platelet membrane biomimicry plasmonic photothermal therapy gold nanorods surgery bleeding dogs cats stimuli-responsive DOX SN38 CSCs single-walled carbon nanotubes chirality separation NASH drug-gene delivery near IR hyperspectral imaging plasmonics copper VEGF glioblastoma differentiated neuroblastoma peptidomimetics real-time quantitative polymerase chain reaction (qPCR) actin combinatorial therapy anticancer and antibacterial activity temoporfin drug-in-cyclodextrin-in-liposome hybrid nanoparticles multicellular tumor spheroids cyclodextrins photodynamic therapy article yet reasonably common within the subject discipline antitumor strategy biomimetic core–shell nanoparticles NK cell-derived exosomes folate receptor albumin nanoparticle microfluidic cabazitaxel polydopamine nanoparticles size cytotoxicity iron affinity FA-DABA-SMA self-assembly oncogenic proteins intracellular disruption folic receptor alpha pancreatic cancer parvifloron D albumin erlotinib photodynamic therapy lipid nanoparticles tumor vectorization verteporfin ovarian carcinomatosis spheroids integrin RGD peptide cancer diagnosis radiotherapy hyperthermia therapy biomimetic nanocarrier membrane-wrapped cancer targeted delivery photothermal therapy imaging cancer nanomedicine tumor microenvironment nano–bio interactions clinical translation magnetic nanowires magnetic hyperthermia magnetic actuation magnetic drug targeting titanate nanotubes gold nanoparticles vectorization colloidal stability docetaxel prostate cancer mangiferin anti-topoisomerase activity extracellular vesicles exosomes chemico-physical functionalization loading translational medicine nanotechnology: bioengineering anacardic acid mitoxantrone targeted drug delivery liposomes melanoma apoptosis ascorbic acid angiogenesis epithelial-to-mesenchymal transition hypoxia immunosuppression metabolism nanotherapeutics tumour microenvironment DNA origami liposome remote loading acute toxicity organoids magnetic silica-coated iron oxide nanochains photothermal treatment hyperthermia collagen cellular microenvironment lymphadenectomy magnetometer sentinel lymph node dissection SPION superparamagnetic iron oxide nanoparticles Vδ2 T cells zoledronic acid polymeric nanoconstruct anti-tumor immunity colorectal carcinoma β-cyclodextrin nanosponges BALB-neuT mice brain tumours glioma blood brain barrier polymeric nanoparticles PEGylation dioleoylphosphatidylethanolamine poly(hydroxyethyl acrylate-co-allyl methyl sulfide) copolymer folate oxidation-sensitive release cellular interaction in vitro anti-cancer activity triple negative breast cancer organotin mesoporous silica nanoparticles MDA-MB-231 theranostic nanomaterials nanobiotechnology molecular imaging nanosystems nanomicelles ovarian cancer tumour targeting chemotherapeutics riboflavin vitamin B2 nanomedicines secondary structure mixed micelle pH responsive targeted therapy anti-cancer shear stress flow in vitro therapeutics diagnostics Immunotherapy |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557114703321 |
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Hoskins Clare
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Crosstalk between MicroRNA and Oxidative Stress in Physiology and Pathology
| Crosstalk between MicroRNA and Oxidative Stress in Physiology and Pathology |
| Autore | Fioravanti Antonella |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 |
| Descrizione fisica | 1 electronic resource (320 p.) |
| Soggetto topico | Medicine |
| Soggetto non controllato |
miR-27a-5p
acute myocardial infarction autophagy apoptosis hypoxia MicroRNA (miRNA) miR526b miR655 oxidative stress reactive oxygen species (ROS) superoxide (SO) Thioredoxin Reductase 1 (TXNRD1) breast cancer nucleic acid medicine pancreatic cancer clinical trial siRNA antisense oligonucleotide MicroRNA signal transduction therapeutic target miRNAs ROS noncoding RNA microRNA long noncoding RNA mitochondrial dysfunction nitrosative stress. exosome cross-talk systemic lupus erythematosus visfatin resistin osteoarthritis synovial fibroblasts synovitis NF-κB thyroid hormone liver cancer metabolism physiology ASH NAFLD NASH HCC HCV HBV endometriosis high-grade serous ovarian cancer endometriosis-associated ovarian cancer epithelial-to-mesenchymal transition chemoresistance antioxidants miRNA cancer diabetes beta cells microRNAs translation regulation neurodegeneration Alzheimer's disease Parkinson's disease Huntington's disease ALS reactive oxygen species redox signaling therapeutic tolerance therapeutic resistance |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557526003321 |
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Fioravanti Antonella
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Kidney Inflammation, Injury and Regeneration 2020
| Kidney Inflammation, Injury and Regeneration 2020 |
| Autore | Baer Patrick C |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 electronic resource (318 p.) |
| Soggetto topico | Medicine |
| Soggetto non controllato |
inflammation
chronic kidney disease anemia anemia of inflammation ESA hyporesponsiveness renal tubular epithelial cells macrophages lipocalin-2 iron cilastatin hypoxia inducible factor-1-α ischemia-reperfusion injury acute kidney injury cyclophilin A fibrosis renal fibrosis tubular necrosis preeclampsia podocytes VEGF FSGS proteinuria endocan ESM-1 renal replacement therapy kidney transplantation biomarker diabetic nephropathy focal segmental glomerulosclerosis innate immunity membranous nephropathy minimal change diseases TLR NOX1 ML171 reactive oxygen species ERK T cells glomerulonephritis chemokines renal disease DJ-1 ND-13 renal inflammation oxidative stress UUO autophagy apoptosis trehalose simvastatin endotoxin tubular apoptosis cytochrome C Bcl-XL survivin hypercholesterolemia xanthine oxidase NF-κB pathway tertiary lymphoid organs B cells BAFF kidney fibrosis myofibroblast activation extracellular matrix Hippo pathway verteporfin IgAN CKD progression ACEI corticosteroids costimulation coinhibition kidney transplant SPR protein binding affinity adaptive immunity epithelial-to-mesenchymal transition E. cava extracts dieckol spontaneously hypertensive rats angiotensin II |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557364503321 |
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Baer Patrick C
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Metastatic Progression and Tumour Heterogeneity
| Metastatic Progression and Tumour Heterogeneity |
| Autore | Hollande Fred |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 |
| Descrizione fisica | 1 electronic resource (312 p.) |
| Soggetto topico | Medicine |
| Soggetto non controllato |
clear cell renal cell carcinoma
tumor evolution tumor ecology intratumor heterogeneity multisite tumor sampling targeted therapy uterine carcinosarcoma endometrial carcinoma metaplastic carcinoma epithelial-to-mesenchymal transition clonality mutation TP53 PI3K/AKT pathway gene expression miRNA expression tumor microenvironment interstitial pH acidosis tumor heterogeneity magnetic resonance imaging hyperpolarized 13C MRI carbonic anhydrase lactic acid positron emission tomography esophageal squamous cell carcinoma precision medicine natural killer cells tumor mutation burden immunotherapy PET heterogeneity radiomics radiopharmaceuticals SUV nuclear medicine colon cancer Wnt signaling phenotypic plasticity EMT hybrid E/M collective and single-cell migration beta-catenin paradox breast cancer immune microenvironment DCIS ADH mammary gland cell fate 3D cultures organoids signaling single-cell RNAseq tumor endothelial cell metastasis angiocrine factor microsatellite instability colorectal cancer immune checkpoints deficient mismatch repair plasticity biomechanics circulating tumor cells (CTCs) extracellular vesicles metastatic niche epigenetics CTC-clusters single-cell analysis cellular heterogeneity circulating tumor cells pancreatic cancer epithelial mesenchymal plasticity target discovery review genomics intra-tumour heterogeneity subclonal diversity treatment resistance |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557105803321 |
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Hollande Fred
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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The Role of Extracellular Matrix in Cancer Development and Progression
| The Role of Extracellular Matrix in Cancer Development and Progression |
| Autore | Tzanakakis George |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 electronic resource (182 p.) |
| Soggetto topico | Research & information: general |
| Soggetto non controllato |
elastin
ribosomal protein SA tongue carcinoma MMP-2 EGCG pancreatic ductal adenocarcinoma syndecans proteoglycans tumor progression angiogenesis syndecan-4 heparan sulfate cancer prognosis biomarker signal transduction proteoglycan metastasis extracellular matrix fibrosis immune cell modulation neutrophils neutrophil extracellular trap macrophages BCC MMP TIMP invasion lumican cancer cell growth motility hyaluronan RHAMM CD44 wound repair breast cancer malignant pleural mesothelioma pleural effusion extracellular vesicles biomarkers sulfated hyaluronan estrogen receptors epithelial-to-mesenchymal transition matrix metalloproteinases |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910566470803321 |
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Tzanakakis George
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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