30 years old [[electronic resources] ] : O-GlcNAc reaches age of reason - regulation of cell signaling and metabolism by O-GlcNAcylation / / edited by Tony Lefebvre and Tarik Issad |
Autore | Tarik Issad |
Pubbl/distr/stampa | Frontiers Media SA, 2015 |
Descrizione fisica | 1 online resource (113 pages) : illustrations |
Disciplina | 572/.567 |
Collana | Frontiers Research Topics |
Soggetto topico |
Cell signalling
Metabolism |
Soggetto non controllato |
nutrition
Hexosamine biosynthetic pathway O GlcNAcylation OGA Inflammation Metabolism OGT Cell signaling epigenetics Cancer |
ISBN | 9782889195916 (eboook) |
Formato | Materiale a stampa ![]() |
Livello bibliografico | Monografia |
Lingua di pubblicazione | eng |
Altri titoli varianti | 30 years old |
Record Nr. | UNINA-9910136401403321 |
Tarik Issad
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Frontiers Media SA, 2015 | ||
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Lo trovi qui: Univ. Federico II | ||
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A Personalized Medicine Approach to the Diagnosis and Management of Autism Spectrum Disorder |
Autore | Frye Richard E |
Pubbl/distr/stampa | Basel, : MDPI Books, 2022 |
Descrizione fisica | 1 electronic resource (416 p.) |
Soggetto topico |
Medicine
Neurosciences |
Soggetto non controllato |
fecal metabolites
ASD microbiome gastrointestinal symptoms Fisher Discriminant Analysis digital biomarkers wearables time series analysis autism social dyads socio-motor parameters network connectivity non-linear complex dynamics stochastic analysis autism spectrum disorders copy number variants females Array-Comparative Genomic Hybridization (Array-CGH) autism spectrum disorder Ehlers-Danlos syndrome hypermobility spectrum disorders autonomic disorder mast cell activation syndrome genetic testing chromosomal microarray analysis whole exome sequencing whole genome sequencing clinical utility polygenic risk scores Temple Grandin biomarker omics precision medicine proteomics transcriptomics epigenetics metabolomics patient stratification mitochondria oxidative stress prenatal environment immune dysfunction immunoglobulin G intravenous immunoglobulin energy metabolism fatty acid oxidation acyl-carnitines resveratrol integrative model concomitant condition disorder autism spectrum disorder (ASD) genomics personalized treatment strategy single nucleotide polymorphisms clinical decision support tool ADHD PANDAS OCD anxiety folate receptor alpha folates pregnancy brain development fetal development cobalamin glutathione methylation methylcobalamin redox metabolism locked-in network syndrome resting-state functional magnetic resonance imaging temporal lobe epilepsy amygdala brain COVID-19 children cytokines flavonoids inflammation luteolin mast cells microglia SARS-CoV-2 stress nutraceuticals survey vitamins minerals B12 folinic acid quality of life parents intervention systematic review medical claims logistic regression analysis retrospective analysis associated risk monoamine neurotransmitters neurotransmitter deficiency cerebral folate deficiency folate receptor alpha autoantibodies leucovorin α-amylase cortisol heart rate variability neuromodulation sleep anxiety transdermal electrical neuromodulation neurostimulation |
Formato | Materiale a stampa ![]() |
Livello bibliografico | Monografia |
Lingua di pubblicazione | eng |
Record Nr. | UNINA-9910595075503321 |
Frye Richard E
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Basel, : MDPI Books, 2022 | ||
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Lo trovi qui: Univ. Federico II | ||
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Advances in Eating Disorders |
Autore | Aguera Zaida |
Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
Descrizione fisica | 1 electronic resource (348 p.) |
Soggetto topico |
Humanities
Social interaction |
Soggetto non controllato |
anorexia nervosa
cognitive interpersonal model severe enduring physical activity accelerometry weight gain eating disorders malnutrition neuroimaging fractal dimension cortical complexity food craving food addiction emotion regulation event related potentials EEG neurophysiology psychopathology ASD comorbidity emotion recognition attention sensory sensitivity autism Avon Longitudinal Study of Parents and Children (ALSPAC) body mass index disordered eating behaviors disordered eating cognitions polygenic scores non-suicidal self-injury temperament eating disorder adolescence nocturnal eating syndrome sleep-related eating disorder parasomnia delayed sleep-wake phase MUPS magnetic resonance spectroscopy MRS insula glutamate N-acetylaspartate NAA epigenetics bulimia nervosa DNA methylation gene-environment interactions caloric intake refeeding syndrome refeeding protocol children and adolescents parents carers intervention workshop online intervention alcohol and/or drug abuse substance use disorder executive functions impulsivity emotional dysregulation deep brain stimulation psychosurgery clinical trial subcallosal cingulate nucleus accumbens high expressed emotion caregivers dance students disordered eating attitudes Eating Attitudes Test-26 (EAT-26) mesomorphy ectomorphy Receiver Operating Characteristics (ROC) curve analysis attention-deficit/hyperactivity disorder ADHD longitudinal treatment outcome dropout rTMS treatment anorexia bulimia binge eating disorders restrictive anorexia nervosa weight recovery animal models acyl-ghrelin desacyl-ghrelin chronic food restriction virtual reality fear of gaining weight body anxiety body image disturbances body-related attentional bias |
Formato | Materiale a stampa ![]() |
Livello bibliografico | Monografia |
Lingua di pubblicazione | eng |
Record Nr. | UNINA-9910557561003321 |
Aguera Zaida
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Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
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Lo trovi qui: Univ. Federico II | ||
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Alterations of epigenetics and microRNAs in cancer and cancer stem cell [[electronic resource] /] / topic editor: Yoshimasa Saito |
Autore | Yoshimasa Saito |
Pubbl/distr/stampa | Frontiers Media SA, 2014 |
Descrizione fisica | 1 online resource (79 pages) : illustrations; digital, PDF file(s) |
Disciplina | 616.99 |
Collana |
Frontiers in research topics
Frontiers in genetics |
Soggetto topico |
Epigenetics
Stem cells Genetics Cancer - Treatment - Research |
Soggetto non controllato |
MicroRNAs
cancer stem cells Methylation epigenetics Cancer |
Formato | Materiale a stampa ![]() |
Livello bibliografico | Monografia |
Lingua di pubblicazione | eng |
Nota di contenuto | Alterations of epigenetics and microRNAs in cancer and cancer stem cell / Yoshimasa Saito -- Culturing intestinal stem cells: applications for colorectal cancer research / Masayuki Fuji and Toshiro Sato -- Characterizing the Retinoblastoma 1 locus: putative elements for Rb1 regulation by in silico analysis / Mohammadreza Hajjari, Atefeh Khoshnevisan and Bernardo Lemos -- Multilayer-omics analyses of human cancers: exploration of biomarkers and drug targets based on the activities of the International Human Epigenome Consortium / Yae Kanai and Eri Arai -- Non-coding RNAs as epigenetic regulator of glioma stem-like cell differentiation / Keisuke Katsushima and Yutaka Kondo -- Aberrantly methylated genes in human papillary thyroid cancer and their association with BRAF/RAS mutation / Yasuko Kikuchi, Eiichi Tsuji, Koichi Yagi, Keisuke Matsusaka, Shingo Tsuji, Junichi Kurebayashi, Toshihisa Ogawa, Hiroyuki Aburatani, Atsushi Kaneda -- MicroRNAs in Barrett's esophagus: future prospects / Juntaro Matsuzaki and Hidekazu Suzuki -- Epigenetic alteration and microRNA dysregulation in cancer / Hiromu Suzuki, Reo Maruyama, Eiichiro Yamamoto and Masahiro Kai -- The role of microRNAs in the regulation of cancer stem cells / Ryou-u Takahashi, Hiroaki Miyazaki and Takahiro Ochiya -- Disruption of the expression and function of microRNAs in lung cancer as a result of epigenetic changes / Kousuke Watanabe and Daiya Takai -- The role of mesenchymal stem cell in cancer development / Hiroshi Yagi and Yuko Kitagawa. |
Record Nr. | UNINA-9910136405603321 |
Yoshimasa Saito
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Frontiers Media SA, 2014 | ||
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Lo trovi qui: Univ. Federico II | ||
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The Alzheimer Conundrum : Entanglements of Dementia and Aging / / Margaret Lock |
Autore | Lock Margaret M. |
Edizione | [Course Book] |
Pubbl/distr/stampa | Princeton : , : Princeton University Press, , 2016 |
Descrizione fisica | 1 online resource (323 p.) |
Disciplina | 362.1968/31 |
Soggetto topico |
Older people - Mental health
Brain - Aging - Molecular aspects Alzheimer's disease - Age factors |
Soggetto non controllato |
APOE
Alois Alzheimer Alzheimer disease Alzheimer enterprise Alzheimer genetics Alzheimer prevention Alzheimer world Alzheimer's disease DNA samples DNA GWAS Huntington disease aging population aging populations aging societies amyloid cascade hypothesis amyloid cascade process behavioral changes biomarkers biosociality breast cancer clinical diagnosis clinical settings control samples dementia diagnosis divination early-onset environmental variables epidemiological research epidemiology epigenetics ethnographic research expert knowledge family practice settings gene function genes genetic testing geneticization genome-wide association studies genomics global economy late-onset localization theory medical publications memory clinics memory loss micro-medical management mild cognitive impairment molecular approach molecular biologists molecularization neuritic amyloid plaques neurofibrillary tangles neuroimaging prevention prodromal public health research throughput technology |
ISBN |
0-691-16847-4
1-4008-4846-6 |
Formato | Materiale a stampa ![]() |
Livello bibliografico | Monografia |
Lingua di pubblicazione | eng |
Nota di contenuto | Acknowledgments -- Orientations -- Making and remaking Alzheimer disease -- Striving to standardize Alzheimer disease -- Paths to Alzheimer prevention -- Embodied risk made visible -- Alzheimer genes: biomarkers of prediction and prevention -- Genome-wide association studies: back to the future -- Living with embodied omens -- Chance untamed and the return of fate -- Transcending entrenched tensions -- Portraits from the mind -- Notes -- Bibliography -- Index. |
Record Nr. | UNINA-9910790678703321 |
Lock Margaret M.
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Princeton : , : Princeton University Press, , 2016 | ||
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Lo trovi qui: Univ. Federico II | ||
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The Alzheimer Conundrum : Entanglements of Dementia and Aging / / Margaret Lock |
Autore | Lock Margaret M. |
Edizione | [Course Book] |
Pubbl/distr/stampa | Princeton : , : Princeton University Press, , 2016 |
Descrizione fisica | 1 online resource (323 p.) |
Disciplina | 362.1968/31 |
Soggetto topico |
Older people - Mental health
Brain - Aging - Molecular aspects Alzheimer's disease - Age factors |
Soggetto non controllato |
APOE
Alois Alzheimer Alzheimer disease Alzheimer enterprise Alzheimer genetics Alzheimer prevention Alzheimer world Alzheimer's disease DNA samples DNA GWAS Huntington disease aging population aging populations aging societies amyloid cascade hypothesis amyloid cascade process behavioral changes biomarkers biosociality breast cancer clinical diagnosis clinical settings control samples dementia diagnosis divination early-onset environmental variables epidemiological research epidemiology epigenetics ethnographic research expert knowledge family practice settings gene function genes genetic testing geneticization genome-wide association studies genomics global economy late-onset localization theory medical publications memory clinics memory loss micro-medical management mild cognitive impairment molecular approach molecular biologists molecularization neuritic amyloid plaques neurofibrillary tangles neuroimaging prevention prodromal public health research throughput technology |
ISBN |
0-691-16847-4
1-4008-4846-6 |
Formato | Materiale a stampa ![]() |
Livello bibliografico | Monografia |
Lingua di pubblicazione | eng |
Nota di contenuto | Acknowledgments -- Orientations -- Making and remaking Alzheimer disease -- Striving to standardize Alzheimer disease -- Paths to Alzheimer prevention -- Embodied risk made visible -- Alzheimer genes: biomarkers of prediction and prevention -- Genome-wide association studies: back to the future -- Living with embodied omens -- Chance untamed and the return of fate -- Transcending entrenched tensions -- Portraits from the mind -- Notes -- Bibliography -- Index. |
Record Nr. | UNINA-9910822422403321 |
Lock Margaret M.
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Princeton : , : Princeton University Press, , 2016 | ||
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Lo trovi qui: Univ. Federico II | ||
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AMP-Activated Protein Kinase Signalling |
Autore | Neumann Dietbert |
Pubbl/distr/stampa | MDPI - Multidisciplinary Digital Publishing Institute, 2019 |
Descrizione fisica | 1 electronic resource (452 p.) |
Soggetto non controllato |
HDACs
transcription epigenetics spermatozoa par complex A769662 MDCK skeletal muscle AID phosphorylation energy metabolism monocytes autophagy CML liver hindlimb suspension pregnancy preeclampsia gestational diabetes mellitus CaMKK2 assisted reproduction techniques nutrient-sensing signals sonic hedgehog protein acetylation glycogen storage disease AMPK adenosine monophosphate-activated protein kinase AICAR indirect calorimetry IL-1? MyHC I(?) HDAC4/5 endothelial cells infection hepatocyte p70S6K lipid metabolism host defense exercise kidney disease heat shock protein ?RIM mycobacteria activation loop developmental origins of health and disease (DOHaD) CREB TAK1 metabolic-inflammation phenylephrine AMP-activated protein kinase (AMPK) KATs 2-methoxyestradiol DNA methylation NLRP3 pump ?-linker steatosis AMPK kinase stress endothelial nitric-oxide synthase vasodilation adherent junctions epithelial cells glycogen Akt synaptic activation cellular energy sensing glucose uptake transporter co-expression atrophy nutrigenomics motility vasoconstriction fatty acid oxidation oxidative stress AS160 membrane histone modification sirtuin 1 (SIRT1) chromatin remodeling insulin signalling dietary fatty acids ULK CMML adaptive thermogenesis mTOR MDS mechanical unloading AML endothelial function medulloblastoma PKA adipose tissue NAD+ membranes nutrition ZO-1 TBC1D4 adipocyte soluble Adenylyl cyclase metabolism renin-angiotensin system energy utilization proteasome differentiation signaling peroxisome proliferator-activated receptor gamma coactivator 1-? (PGC1?) hypertrophy AMP-activated protein kinase metabolic disease LKB1 soleus muscle macrophages Immediate early genes CBS benign motor endplate remodeling ionomycin nectin-afadin tight junctions resveratrol protein kinase B regrowth mitochondria protein synthesis energy deficiency catechol-O-methyltransferase fiber-type microarrays carrier acetyl-CoA hypertension 3T3-L1 hypothalamus food intake |
Formato | Materiale a stampa ![]() |
Livello bibliografico | Monografia |
Lingua di pubblicazione | eng |
Record Nr. | UNINA-9910346858503321 |
Neumann Dietbert
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MDPI - Multidisciplinary Digital Publishing Institute, 2019 | ||
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Lo trovi qui: Univ. Federico II | ||
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Animal Modeling in Cancer |
Autore | Korinek Vladimir |
Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
Descrizione fisica | 1 electronic resource (273 p.) |
Soggetto topico |
Research & information: general
Biology, life sciences |
Soggetto non controllato |
soy
isoflavones mammary tumor prevention rodent models chemical carcinogens transgenic mice Zebrafish Drosophila rats mice NPM-1 FLT3 ITD ETO-1 IDH1/2 neural stem cells brain and nervous system cancers neurogenic niches radiotherapy sparing of neurogenic regions carcinoma consensus molecular subtypes intestine oncogenes signaling cascades tumor suppressors tumorigenesis MPN (myeloproliferative neoplasms) zebrafish iPSCs JAK2 MPL CALR thrombosis ubiquitin–proteasome system cancer mouse model gene inactivation colorectal cancer mouse models microbiota antitumor immunity melanoma mutation genetics animal model swine MeLiM progression spontaneous regression devitalization metaplasia Cdx animal models epigenetics xenotransplantation drug screen pre-clinical cancer model non-mouse models gene editing stem cells solid tumors hematologic malignancies |
Formato | Materiale a stampa ![]() |
Livello bibliografico | Monografia |
Lingua di pubblicazione | eng |
Record Nr. | UNINA-9910557344403321 |
Korinek Vladimir
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Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
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Lo trovi qui: Univ. Federico II | ||
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Application of Bioinformatics in Cancers |
Autore | Brenner J. Chad |
Pubbl/distr/stampa | MDPI - Multidisciplinary Digital Publishing Institute, 2019 |
Descrizione fisica | 1 electronic resource (418 p.) |
Soggetto non controllato |
cancer treatment
extreme learning independent prognostic power AID/APOBEC HP gene inactivation biomarkers biomarker discovery chemotherapy artificial intelligence epigenetics comorbidity score denoising autoencoders protein single-biomarkers gene signature extraction high-throughput analysis concatenated deep feature feature selection differential gene expression analysis colorectal cancer ovarian cancer multiple-biomarkers gefitinib cancer biomarkers classification cancer biomarker mutation hierarchical clustering analysis HNSCC cell-free DNA network analysis drug resistance hTERT variable selection KRAS mutation single-cell sequencing network target skin cutaneous melanoma telomeres Neoantigen Prediction datasets clinical/environmental factors StAR PD-L1 miRNA circulating tumor DNA (ctDNA) false discovery rate predictive model Computational Immunology brain metastases observed survival interval next generation sequencing brain machine learning cancer prognosis copy number aberration mutable motif steroidogenic enzymes tumor mortality tumor microenvironment somatic mutation transcriptional signatures omics profiles mitochondrial metabolism Bufadienolide-like chemicals cancer-related pathways intratumor heterogeneity estrogen locoregionally advanced RNA feature extraction and interpretation treatment de-escalation activation induced deaminase knockoffs R package copy number variation gene loss biomarkers cancer CRISPR overall survival histopathological imaging self-organizing map Network Analysis oral cancer biostatistics firehose Bioinformatics tool alternative splicing biomarkers diseases genes histopathological imaging features imaging TCGA decision support systems The Cancer Genome Atlas molecular subtypes molecular mechanism omics curative surgery network pharmacology methylation bioinformatics neurological disorders precision medicine cancer modeling miRNAs breast cancer detection functional analysis biomarker signature anti-cancer hormone sensitive cancers deep learning DNA sequence profile pancreatic cancer telomerase Monte Carlo mixture of normal distributions survival analysis tumor infiltrating lymphocytes curation pathophysiology GEO DataSets head and neck cancer gene expression analysis erlotinib meta-analysis traditional Chinese medicine breast cancer TCGA mining breast cancer prognosis microarray DNA interaction health strengthening herb cancer genomic instability |
ISBN | 3-03921-789-5 |
Formato | Materiale a stampa ![]() |
Livello bibliografico | Monografia |
Lingua di pubblicazione | eng |
Record Nr. | UNINA-9910367743403321 |
Brenner J. Chad
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MDPI - Multidisciplinary Digital Publishing Institute, 2019 | ||
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Lo trovi qui: Univ. Federico II | ||
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Autoinflammatory Diseases: From Genes To Bedside |
Autore | Soriano Alessandra |
Pubbl/distr/stampa | Frontiers Media SA, 2020 |
Descrizione fisica | 1 electronic resource (168 p.) |
Soggetto topico |
Medicine
Immunology |
Soggetto non controllato |
autoinflammatory diseases
genotype/phenotype correlations inflammasome ubiquitinopathies hyperinflammatory state epigenetics dermatopathology treatment |
Formato | Materiale a stampa ![]() |
Livello bibliografico | Monografia |
Lingua di pubblicazione | eng |
Altri titoli varianti | Autoinflammatory Diseases |
Record Nr. | UNINA-9910557529003321 |
Soriano Alessandra
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Frontiers Media SA, 2020 | ||
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Lo trovi qui: Univ. Federico II | ||
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