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A Milestone in Frontiers in Pharmacology: 1,000 Published Papers in the Section Experimental Pharmacology and Drug Discovery
| A Milestone in Frontiers in Pharmacology: 1,000 Published Papers in the Section Experimental Pharmacology and Drug Discovery |
| Autore | Salomone Salvatore |
| Pubbl/distr/stampa | Frontiers Media SA, 2020 |
| Descrizione fisica | 1 electronic resource (266 p.) |
| Soggetto topico |
Science: general issues
Pharmacology |
| Soggetto non controllato |
experimental pharmacology
drug discovery drug action receptors enzymes ion channels transporters transcription factors |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | Milestone in Frontiers in Pharmacology |
| Record Nr. | UNINA-9910557483603321 |
Salomone Salvatore
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| Frontiers Media SA, 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Amide Bond Activation
| Amide Bond Activation |
| Autore | Szostak Michal |
| Pubbl/distr/stampa | MDPI - Multidisciplinary Digital Publishing Institute, 2019 |
| Descrizione fisica | 1 electronic resource (466 p.) |
| Soggetto non controllato |
N-heterocyclic carbene
non planar amide ruthenium (Ru) physical organic chemistry gemcitabine prodrug pyramidal amides bridged sultams catalysis dipeptides N-(1-naphthyl)acetamide C-N ? bond cleavage steric effects peptide bond cleavage transition-metal-free palladium N-heterocyclic carbenes (NHCs) addition reaction C–O activation rhodium metal complexes carbanions thioamidation amide bond intramolecular catalysis antiviral activity additivity principle pre-catalysts C–N bond cleavage bridged lactams C–H acidity arynes twisted amides organic synthesis amination Suzuki-Miyaura tert-butyl cyclopentadienyl complexes C-S formation enzymes DFT study sulfonamide bond N HERON reaction primaquine entropy amide activation amidation synthesis amide hydrolysis carbonylicity amide bond activation amide bond resonance aminosulfonylation molecular dynamics model compound in situ amide homogeneous catalysis heterocycles anomeric effect multi-component coupling reaction kinetic excited state C–H bond cleavage palladium catalysis amides thiourea formylation alkynes cis/trans isomerization amide C–N bond activation intein C-H functionalization succindiamide amide bonds crown ether aminoacylation directing groups cytostatic activity reaction thermodynamics acyl transfer transition metals N-dimethylformamide DMAc acylative cross-coupling C-H/C-N activation nickel catalysis antibacterial screening sodium aryl thioamides Winkler-Dunitz parameters catalyst N-dimethylacetamide base-catalyed hydrolysis nitrogen heterocycles cross-coupling insertion amidicity nitro-aci tautomerism activation carbonylation transamidation amine distortion Pd-catalysis rotational barrier energy hypersensitivity N–C activation metabolic stability [2+2+2] annulation twisted amide protease cyanation amide resonance trialkylborane catalysts biofilm eradication pharmacokinetics pancreatic cancer cells DMF aryl esters Michael acceptor fumardiamide water solvation ester bond activation cyclization nuclear magnetic resonance secondary amides reaction mechanism density functional theory density-functional theory amino acid transporters |
| ISBN | 3-03921-204-4 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910346843703321 |
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Szostak Michal
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| MDPI - Multidisciplinary Digital Publishing Institute, 2019 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Biocatalytic Process Optimization
| Biocatalytic Process Optimization |
| Autore | Kuo Chia-Hung |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 electronic resource (296 p.) |
| Soggetto topico | Research & information: general |
| Soggetto non controllato |
catechin
degalloylation flavonol glycoside hydrolase optimization tannase immobilized DERA statin side chain continuous flow synthesis alginate-luffa matrix design of experiments Anguilla marmorata eel protein hydrolysates functional properties herbal eel extracts agarose agarase agarotriose agaropentaose expression calycosin calycosin-7-O-β-D-glucoside glucosyltransferase sucrose synthase UDP-glucose recycle UGT-SuSy cascade reaction Candida antarctica lipase A surface-display system shear rate mass transfer rate enzymatic kinetic study enzymatic synthesis β-amino acid esters microreactor aromatic amines Michael addition kraft pulp cellulose xylan enzymatic hydrolysis Penicillium verruculosum glucose xylose lipase acidolysis docosahexaenoic acid ethyl ester eicosapentaenoic acid ethyl ester ethyl acetate kinetics styrene monooxygenase indole monooxygenase two-component system chiral biocatalyst solvent tolerance biotransformation epoxidation NAD(P)H-mimics superoxide dismutase (SOD) catalase (CAT) glutathione reductase (GR) aluminum (Al) selenium (Se) mouse brain liver phosphatidylcholine 3,4-dimethoxycinnamic acid enzymatic interesterification biocatalysis Pleurotus ostreatus enenzymatic hydrolysis peptide antioxidant hepatoprotective activity Yarrowia lipolytica whole-cell biocatalysis indolizine cycloaddition trehalose viscosity enzymes protein dynamics Kramers' theory protein stabilization enzyme inhibition Lipase transesterification 2-phenylethyl acetate packed-bed reactor solvent-free cyclic voltammetry electrochemical impedance spectroscopy carbon nanotubes redox mediators CYP102A1 naringin dihydrochalcone neoeriocitrin dihydrochalcone regioselective hydroxylation |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557487503321 |
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Kuo Chia-Hung
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Biosensors for Diagnosis and Monitoring
| Biosensors for Diagnosis and Monitoring |
| Autore | Mir Mònica |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 electronic resource (318 p.) |
| Soggetto topico |
Research & information: general
Chemistry Analytical chemistry |
| Soggetto non controllato |
biosensors
interdigitated electrodes impedance spectroscopy blood analysis whole-cell biosensor yeast surface display cholesterol oxidase glucose dehydrogenase electrochemical detection fiber optic sensor vital signs biosensor human body body temperature heart rate respiratory rate blood pressure torso scanning antennas processing algorithms electromagnetic imaging polymerase chain reaction COVID-19 electrochemical digital PCR point-of-care electroanalysis indigo dyes fast identification fingerprints differential pulse voltammetry cystatin C molecularly imprinted polymer electrochemical biosensor polypyrene multiwall carbon nanotubes acute kidney injury biomonitoring personalized healthcare sweat rolling circle amplification environmental monitoring heavy metals organic molecules microorganisms biorecognition diagnosis pathogens aptamers antibodies peptides enzymes DNAzymes peptide nucleic acids blood glucose monitoring diabetes non-invasive sensor PDMS vascular phantom glucometer RF sensor CD4+ T helper cells microfluidic chip microbeads wide-field optical system ImageJ graphene reduced graphene oxide electrochemistry electrochemical impedance spectroscopy DNA biosensor diazonium chemistry screen-printed electrodes DNA hybridization VOCs environmental packaging diagnostic pollution colorectal cancer KRAS lateral flow assay dipstick gold nanoparticles diagnostics multiplex point-of-care diagnostics REASSURED |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910566463503321 |
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Mir Mònica
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Cell-Free Synthetic Biology
| Cell-Free Synthetic Biology |
| Autore | Hong Seok Hoon |
| Pubbl/distr/stampa | MDPI - Multidisciplinary Digital Publishing Institute, 2020 |
| Descrizione fisica | 1 electronic resource (152 p.) |
| Soggetto non controllato |
genomically engineered E. coli
in vitro transcription-translation (TX-TL) tPa tissue plasminogen activator in vitro translation enzymes DNA origami antimicrobials cell-free metabolic engineering (CFME) cell-free transcription-translation in vitro protein synthesis cell-free metabolic engineering E. coli crude extract preparation chaperones ischemic stroke microsomes sonication cell-free protein synthesis growth factors artificial cell unnatural protein cell-free synthetic biology rapid prototyping drug development unnatural amino acid eukaryotic lysates cell-free protein expression (CFPE) riboregulator synthetic biology mathematical model CFPS cell-free protein synthesis (CFPS) bioconversion platform colicins protein production |
| ISBN | 3-03928-023-6 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910372785403321 |
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Hong Seok Hoon
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| MDPI - Multidisciplinary Digital Publishing Institute, 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Enological Repercussions of Non-Saccharomyces Species
| Enological Repercussions of Non-Saccharomyces Species |
| Autore | Morata Antonio |
| Pubbl/distr/stampa | MDPI - Multidisciplinary Digital Publishing Institute, 2019 |
| Descrizione fisica | 1 electronic resource (218 p.) |
| Soggetto non controllato |
wine acidity
pulcherrimin glycosidases Lactobacillus plantarum Saccharomycodes ludwigii sparkling wine processing foods non-Saccharomyces taxonomy Candida stellate wine quality Candida stellata non-Saccharomyces yeast Brettanomyces bruxellensis flavor complexity Schizosaccharomyces pombe Wickerhamomyces anomalus Stermerella bacillaris mixed cultures fermentation oenological uses winemaking re-fermentation Zygosaccharomyces rouxii Torulaspora delbrueckii genetic improvement Zygotorulaspora florentina maloalcoholic fermentation high-ethanol mixed starters yeast wines non-Saccharomyces yeasts aroma compounds spoilage yeasts' control metabolism acetate esters Pichia anomala wine sequential fermentations spoilage-control enzymes yeast dominance acidification ageing-on-lees Kluyveromyces thermotolerans co-fermentation biotechnological applications stable pigments ecology Pichia kudriavzevii Lachancea thermotolerans Metschnikowia pulcherrima biocontrol S. ludwigii Candida intermedia nitrogen yeast inoculation volatile acidity off-flavors malolactic bacteria wine safety genome Aureobasidium pullulans viticulture anthocyanin aroma antimicrobial peptides |
| ISBN | 3-03921-559-0 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910367749903321 |
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Morata Antonio
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| MDPI - Multidisciplinary Digital Publishing Institute, 2019 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Functional Cereal Foods for Health Benefits: Genetic and/or Processing Strategies to Enhance the Quali-Quantitative Composition of Bioactive Components
| Functional Cereal Foods for Health Benefits: Genetic and/or Processing Strategies to Enhance the Quali-Quantitative Composition of Bioactive Components |
| Autore | Laddomada Barbara |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 electronic resource (228 p.) |
| Soggetto topico |
Research & information: general
Biology, life sciences |
| Soggetto non controllato |
coix seed
Monascus purpureus antioxidant fermentation HEp2 buckwheat dehulling germination LC-MS free phenolic bound phenolic antioxidant activity sorghum phenolic compounds cell growth inhibition cell cycle analysis apoptosis HepG2 Caco-2 wheat nutrients celiac disease wheat allergy non-celiac wheat/gluten sensitivity durum wheat milling fractions air-classification plant micronization plant sorghum phenolics anti-inflammatory anti-proliferative anti-diabetic anti-atherogenic Triticum aestivum L. Triticum durum Desf gluten breadmaking durum grains genetic variability heritability climate constraints yield performance air-classified fractions alveographic properties antioxidants starch ATI glutenins gluten strength grain protein content haplotypes SNPs milling methods dietary fiber phenolic acid steamed bread leavened pancake multiple linear regression (MLR) artificial neural network (ANN) milled rice enzymes air classification inorganic contaminants organic contaminants arsenic mycotoxins maize inbred lines nutritional value protein quality |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | Functional Cereal Foods for Health Benefits |
| Record Nr. | UNINA-9910585944403321 |
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Laddomada Barbara
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Fundamentals of Enhanced Oil Recovery
| Fundamentals of Enhanced Oil Recovery |
| Autore | Kremieniewski Marcin |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 electronic resource (268 p.) |
| Soggetto topico |
Technology: general issues
History of engineering & technology |
| Soggetto non controllato |
gas migration
well cementing cement slurry cement sheath corrosion resistance gas outflows oil-based mud invert drilling fluid water phase oil phase emulsion stability emulsifier drilling mud oxidants enzymes filter cake improving the sealing of the borehole rational selection of drilling fluids cleaning the borehole adhesion spacer fluid CO2 and H2S geological sequestration acid gas reinjection acid gas migration bottomhole sampling isotopic composition gas and water chemical analysis soil gas analysis leakage risk analysis improved borehole sealing nanosilica cement stone mechanical parameters drilling fluids wash mud cake annular space borehole cleaning cementing wash contact time high temperature on corrosion of mining pipes water aggressive natural gas components L80-1 steel water shut-off treatment gas production water-gas ratio (WGR) formation permeability well logging data quality and quantity interpretation gas well ranking water flooding pore scale enhanced oil recovery viscosity capillarity jet pump oil well sucker-rod pump gas-water-oil mixture chrome coating unconventional resources shale gas oil gas total organic carbon (TOC) cluster analysis genetic type of kerogen WAG carbonate reservoir CO2 acid gas high-nitrogen natural gas water alternating gas EOR recovery factor genetic programming fine-grained material borehole sealing efficiency technological parameters |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910585938103321 |
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Kremieniewski Marcin
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Marine Enzymes : Sources, Biochemistry and Bioprocesses for Marine Biotechnology
| Marine Enzymes : Sources, Biochemistry and Bioprocesses for Marine Biotechnology |
| Autore | Trincone Antonio |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 |
| Descrizione fisica | 1 electronic resource (378 p.) |
| Soggetto topico |
Research & information: general
Biology, life sciences |
| Soggetto non controllato |
metalloprotease
adsorption analysis molecular docking affinity purification aminophenylboronic acid alginate degradation 4-deoxy-l-erythro-5-hexoseulose uronic acid (DEH) metabolism Bacteroidetes Proteobacteria Flavobacterium 2-keto-3-deoxy-d-gluconate (KDG) kinase 2-keto-3-deoxy-6-phosphogluconate (KDPG) aldolase alginate-derived products marine enzymes biocatalysts bioprocesses biorefinery seafood marine biomarkers collagenase fermentation optimization collagen Pseudoalteromonas antioxidant peptides microcystin-degrading bacteria mycotoxin protease esterase inhibitor marine agent Catenovulum alkaline and cold-adapted dextranase isomaltoogligosaccharides biofilm dental caries growing cells resting cells asymmetric reduction marine fungi chiral alcohols alginate lyase marine bacterium Bacillus sp. Alg07 purification alginate oligosaccharides Vibrio weizhoudaoensis PL7 family salt-activated enzyme Serratia marcescens polyM-specific oligosaccharides Isoptericola halotolerans bifunctional alginate lyase α-d-galactosidase homology model GH 36 family mutation transglycosylation marine bacteria Pseudoalteromonas sp. KMM 701 leucine dehydrogenase cold-adapted Antarctic bacterium sea-ice homology modeling fucoidan endo-fucoidanase galactofucan molecular stabilisation Sargassum mcclurei Turbinaria ornata Alteromonas deep sea cold-adapted enzyme β-galactosidase lactose-free milk chitosanases chitin deacetylase deacetylation patterns chitooligosaccharides separating detecting expression deep-sea enzyme pCold vector Ascophyllum nodosum algal cell wall degrading enzymes enzyme-assisted extraction ichip device quorum quenching enzyme error prone PCR high-throughput screening site-directed mutagenesis catalytic ability Pectobacterium carotovorum subsp. carotovorum (Pcc) Alginate lyase Thermo-tolerant pH-stability Endo-manner Vibrio sp. SY01 polysaccharide lyase of family 6 characterization degradation pattern microalgae enzymes marine biotechnology -omics technologies heterologous expression homologous expression |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | Marine Enzymes |
| Record Nr. | UNINA-9910557671503321 |
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Trincone Antonio
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Marine Microbial Diversity as Source of Bioactive Compounds
| Marine Microbial Diversity as Source of Bioactive Compounds |
| Autore | Shaaban Khaled A |
| Pubbl/distr/stampa | Basel, : MDPI Books, 2022 |
| Descrizione fisica | 1 electronic resource (182 p.) |
| Soggetto topico | Medicine |
| Soggetto non controllato |
co-culture
marine microbes natural products structural diversity biological activities food allergy deep-sea-derived viridicatol X-ray single crystal intestinal barrier mast cell calcium influx Chlorella enzymes lipases molecular modeling sulfated polysaccharides antiviral SARS-CoV-2 docking molecular dynamic simulations sea cucumber bioactivity diversity microorganism polyketides alkaloids marine-derived fungus Penicillium sp indole-diterpenoids cytotoxicity antibacterial activity Leizhou Peninsula mangrove soil actinomycetia antimicrobial activity secondary metabolites dereplication metabolomics tools trioxacarcins mansouramycins isoquinolinequinones marine-derived Streptomyces sp |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910595068803321 |
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Shaaban Khaled A
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| Basel, : MDPI Books, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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