Info
A Personalized Medicine Approach to the Diagnosis and Management of Autism Spectrum Disorder
| A Personalized Medicine Approach to the Diagnosis and Management of Autism Spectrum Disorder |
| Autore | Frye Richard E |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 online resource (416 p.) |
| Soggetto topico |
Medicine and Nursing
Neurosciences |
| Soggetto non controllato |
acyl-carnitines
ADHD amygdala anxiety Array-Comparative Genomic Hybridization (Array-CGH) ASD associated risk autism autism spectrum disorder autism spectrum disorder (ASD) autism spectrum disorders autonomic disorder B12 biomarker brain brain development cerebral folate deficiency children chromosomal microarray analysis clinical decision support tool clinical utility cobalamin concomitant condition copy number variants cortisol COVID-19 cytokines digital biomarkers disorder Ehlers-Danlos syndrome energy metabolism epigenetics fatty acid oxidation fecal metabolites females fetal development Fisher Discriminant Analysis flavonoids folate receptor alpha folate receptor alpha autoantibodies folates folinic acid gastrointestinal symptoms genetic testing genomics glutathione heart rate variability hypermobility spectrum disorders immune dysfunction immunoglobulin G inflammation integrative intervention intravenous immunoglobulin leucovorin locked-in network syndrome logistic regression analysis luteolin mast cell activation syndrome mast cells medical claims metabolomics methylation methylcobalamin microbiome microglia minerals mitochondria model monoamine neurotransmitters n/a network connectivity neuromodulation neurostimulation neurotransmitter deficiency non-linear complex dynamics nutraceuticals OCD omics oxidative stress PANDAS parents patient stratification personalized treatment strategy polygenic risk scores precision medicine pregnancy prenatal environment proteomics quality of life redox metabolism resting-state functional magnetic resonance imaging resveratrol retrospective analysis SARS-CoV-2 single nucleotide polymorphisms sleep anxiety social dyads socio-motor parameters stochastic analysis stress survey systematic review Temple Grandin temporal lobe epilepsy time series analysis transcriptomics transdermal electrical neuromodulation vitamins wearables whole exome sequencing whole genome sequencing α-amylase |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910595075503321 |
Frye Richard E
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Adipokines 2.0
| Adipokines 2.0 |
| Autore | Büchler Christa |
| Pubbl/distr/stampa | MDPI - Multidisciplinary Digital Publishing Institute, 2020 |
| Descrizione fisica | 1 online resource (406 p.) |
| Soggetto topico | Medicine |
| Soggetto non controllato |
adipokine
adipokines adiponectin adipose tissue adipose-brain axis alpha-fetoprotein annexins biologic activity biomarker brain health C-C chemokine receptor-like 2 cancer Cardiovascular Diseases (CVDs) cathepsins chemerin chemerin receptors chemokine-like receptor 1 cholesterol complement factors critical illness depression early pregnancy early-life programming energy metabolism EP3 receptor EP4 receptor epicardial adipose tissue (EAT) excessive gestational weight gain exchange protein directly activated by cAMP isoform 2 (EPAC2) extracellular remodeling fat mass fatty liver fitness follicular fluid free fatty acids G protein-coupled receptor 1 gestational diabetes ghrelin glucose homeostasis glucose restriction human granulosa cells hypertension hypothalamus ICU in vitro fat regain inflammation insulin interleukin(IL)-33 label-free proteomic profiling leptin leukocyte lipid metabolism lipids liver steatosis metabolically healthy obese microglia myokine n/a neonatal anthropometry neurodegeneration Nonalcoholic fatty liver disease obesity oestrous cycle osteoarthritis ovary PCOS pig polycystic ovary morphology polycystic ovary syndrome preeclempsia prognosis prostaglandin E2 (PGE2) proteolysis resistin rheumatic diseases rheumatoid arthritis secreted frizzled-related protein 5 sepsis SGBS adipocytes sick fat stimulating growth factor 2 (ST2) Tango bioassay testicular pathologies testis tocilizumab triglycerides visceral fat weight regain |
| ISBN | 3-03928-587-4 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910404092003321 |
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Büchler Christa
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| MDPI - Multidisciplinary Digital Publishing Institute, 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Advances in the Biology of Phototrophic Bacteria
| Advances in the Biology of Phototrophic Bacteria |
| Autore | Imhoff Johannes F |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 online resource (274 p.) |
| Soggetto topico | Research and information: general |
| Soggetto non controllato |
adhesion protein
aerobic anoxygenic phototrophic bacteria aerobic anoxygenic phototrophs alkaliphilic bacteria Alphaproteobacteria anoxygenic phototroph anoxygenic phototrophic bacteria antisense promoters bacteriochlorophyll a bacteriochlorophyll biosynthesis bacteriochlorophyll g bioerosion biological soil crust carbon fixation CAS assay ChpT Chromocurvus halotolerans strain EG19 Crp/Fnr Dnr drylands e-pili ectoine biosynthesis energy metabolism euendolith evolution of anoxygenic photosynthesis filamentous anoxygenic phototroph gene transfer agent genomes of photosynthetic bacteria glycine betaine biosynthesis green sulfur bacteria heliobacteria Heliorestis convoluta hot springs iron-sulfur cluster Irr isc genes IscR large multiheme cytochrome massive blooms metagenomic binning metallophore metatranscriptomics microbial mats microbiome motility n/a niche partitioning nitric oxide nitrogen fixing cyanobacteria osmotic adaptation OxyR photooxidative stress photosynthesis genes photosynthetic reaction center proteins photosynthetic symbionts phototrophic purple bacteria phylogenomics phylogeny phylogeny of osmolyte biosynthesis proteomics pufM gene purple nonsulfur bacteria quorum sensing RegA Rhodobacter capsulatus Rhodobacter sphaeroides Rhodobacteraceae rhodopsin Rhodovulum siderophore soda lake Sphingomonadaceae stress defense suf genes syntrophy transcriptomics |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557401903321 |
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Imhoff Johannes F
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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AMP-Activated Protein Kinase Signalling
| AMP-Activated Protein Kinase Signalling |
| Autore | Neumann Dietbert |
| Pubbl/distr/stampa | MDPI - Multidisciplinary Digital Publishing Institute, 2019 |
| Descrizione fisica | 1 online resource (452 p.) |
| Soggetto topico | Biology, life sciences |
| Soggetto non controllato |
?-linker
?RIM 2-methoxyestradiol 3T3-L1 A769662 acetyl-CoA activation loop adaptive thermogenesis adenosine monophosphate-activated protein kinase adherent junctions adipocyte adipose tissue AICAR AID Akt AML AMP-activated protein kinase AMP-activated protein kinase (AMPK) AMPK AMPK kinase AS160 assisted reproduction techniques atrophy autophagy beiging CaMKK2 carrier catechol-O-methyltransferase CBS cellular energy sensing chromatin remodeling CML CMML co-expression CREB developmental origins of health and disease (DOHaD) dietary fatty acids differentiation DNA methylation endothelial cells endothelial function endothelial nitric-oxide synthase energy deficiency energy metabolism energy utilization epigenetics epithelial cells exercise fatty acid oxidation fiber-type food intake gestational diabetes mellitus glucose uptake glycogen glycogen storage disease HDAC4/5 HDACs heat shock protein hepatocyte hindlimb suspension histone modification host defense hypertension hypertrophy hypothalamus IL-1? Immediate early genes indirect calorimetry infection insulin signalling ionomycin KATs kidney disease lipid metabolism liver LKB1 macrophages MDCK MDS mechanical unloading medulloblastoma membrane membranes metabolic disease metabolic-inflammation metabolism microarrays mitochondria monocytes motility motor endplate remodeling mTOR mycobacteria MyHC I(?) n/a NAD+ nectin-afadin NLRP3 nutrient-sensing signals nutrigenomics nutrition oxidative stress p70S6K par complex peroxisome proliferator-activated receptor gamma coactivator 1-? (PGC1?) phenylephrine phosphorylation PKA preeclampsia pregnancy proteasome protein acetylation protein kinase B protein synthesis pump regrowth renin-angiotensin system resveratrol signaling sirtuin 1 (SIRT1) skeletal muscle soleus muscle soluble Adenylyl cyclase sonic hedgehog spermatozoa steatosis stress synaptic activation TAK1 TBC1D4 tight junctions transcription transporter ULK vasoconstriction vasodilation ZO-1 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910346858503321 |
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Neumann Dietbert
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| MDPI - Multidisciplinary Digital Publishing Institute, 2019 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Benefits of Resveratrol Supplementation / María P. Portillo, Alfredo Fernandez-Quintela
| Benefits of Resveratrol Supplementation / María P. Portillo, Alfredo Fernandez-Quintela |
| Autore | Portillo María P |
| Pubbl/distr/stampa | MDPI - Multidisciplinary Digital Publishing Institute, 2019 |
| Descrizione fisica | 1 electronic resource (260 p.) |
| Soggetto topico | Biology, life sciences |
| Soggetto non controllato |
polyphenols
?-viniferin leptin resistance p53 kidney energy restriction grape powder extract cytokines phosphorylation obesity energy metabolism metabolic pathways endothelial function polyol pathway antioxidant caloric restriction rat adipose tissue microparticles pathways angiotensin converting enzyme 2 resistance esRAGE interleukins metabolic syndrome dissolution rate thermogenesis streptozotocin bioavailability solubility metabolism renin-angiotensin system microbiota Sirt-1 magnesium dihydroxide hypertrophy metabolic diseases physiological adaption red wine extract lens distribution MTA1 sirtuin inflammation cardiac function rats cisplatin resveratrol mitochondria breast cancer ischemia-reperfusion cardiovascular metabolites gut microbiota prostate cancer performance type 2 diabetes cafeteria diet high-fat high-sucrose diet resistance exercise aging diabetes oxidative stress |
| ISBN |
9783039212767
3039212761 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910346854603321 |
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Portillo María P
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| MDPI - Multidisciplinary Digital Publishing Institute, 2019 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Creatine Supplementation for Health and Clinical Diseases
| Creatine Supplementation for Health and Clinical Diseases |
| Autore | Kreider Richard B |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 online resource (562 p.) |
| Soggetto topico |
Biology, life sciences
Food & society Research & information: general |
| Soggetto non controllato |
activated protein kinase (AMPK)
adaptive immunity adenosine 5'-monopnophosphate-activated protein kinase Adenosine mono-phosphate (AMP) adipose tissue amino acids amyotrophic lateral sclerosis anemia anthracycline anthracyclines anti-inflammatory anticancer antioxidant athletes athletic performance atrophy bioinformatics BMI-for-age brain injury cachexia cancer immunotherapy cardiac infarction cardiac signaling cardiac toxicity cardiopulmonary disease cardiotoxicity cardiovascular disease cell survival cellular allostasis cellular metabolism children chronic fatigue chronic fatigue syndrome clinical trial cognition cognitive impairment concussion creatine creatine kinase creatine kinase (CK) creatine perfusion creatine supplementation creatine synthesis deficiencies creatine transporter creatine transporter (CrT) Crohn's disease cytotoxic T cells depression development diabetes dietary ingredients dietary supplement dietary supplements doxorubicin dynamic biosensor energy metabolism ergogenic aid ergogenic aids exercise exercise performance female fertility frailty GAA glucose transporter (GLUT) glycemic control growth heart heart failure height hemodialysis hormones hyperhomocysteinemia hypertrophy hypoxia immobilization immunity inflammation inflammatory bowel diseases (IBD) innate immunity intestinal epithelial cell protection intestinal tissue protection intradialytic creatine supplementation ischemia liver kinase B1 (LKB1) long COVID macrophage polarization MAP kinase signaling system MCDA menopause menstrual cycle metabolic regulator methylation mitochondria mitochondrial cytopathy mitochondrial permeability transition pore (mPTP) mitochondriopathia mood muscle muscle atrophy muscle damage muscle fatigue muscle strength muscle weakness muscular adaptation muscular dystrophy muscular power myocardial infarction neurodegenerative diseases neuromodulation newborn noncommunicable disease nutritional supplements organ transplantation osteoporosis osteosarcopenia oxidative stress Parkinson's Disease performance phosphagens phosphocreatine phosphocreatine (PCr) phosphorylcreatine physiological adaptation pleiotropic effects of creatine (Cr) supplementation post-viral fatigue syndrome pregnancy protein energy wasting reactive oxygen species (ROS) recovery rehabilitation resistance exercise resistance training sarcopenia signal transduction skeletal muscle sodium-chloride-dependent neurotransmitter symporters soy spinal cord injury sports nutrition stature-for-age strength stroke supplementation supplements systems biology T cell antitumor immunity thermogenesis toll-like receptors toxicity training traumatic brain injury treatment type 2 diabetes mellitus ulcerative colitis vascular health vascular pathology vegetarian/vegan diet weightlifting youth |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910566476003321 |
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Kreider Richard B
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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DNA Replication Stress / Robert M. Brosh
| DNA Replication Stress / Robert M. Brosh |
| Autore | Brosh Robert M |
| Pubbl/distr/stampa | MDPI - Multidisciplinary Digital Publishing Institute, 2019 |
| Descrizione fisica | 1 electronic resource (368 p.) |
| Soggetto topico | Biology, life sciences |
| Soggetto non controllato |
Werner Syndrome
A549 cells epigenetic neurodegeneration Genome integrity adaptation cellular senescence genome instability Werner Syndrome Protein lipofuscin cell cycle checkpoints exonuclease 1 template-switching energy metabolism mutation frequency DNA replication fork regression motor neuron disease Microsatellites Alzheimer's disease chromatin remodeler repair of DNA damage AP site analogue mutagens replication timing Thermococcus eurythermalis nucleolar stress gene expression mutations spectra origin firing Fanconi Anemia superfamily 2 ATPase DNA translocation DNA repair SSB signaling homologous recombination common fragile sites 8-chloro-adenosine replication genome stability mutagenicity fork reversal multiple sclerosis non-B DNA protein stability heterogeneity ubiquitin SenTraGorTM (GL13) replication restart EdU ?-arrestin NER aging SSB end resection oxidative stress ATR dormant origins R loops DNA damage response Difficult-to-Replicate Sequences DNA double-strand repair endonuclease IV ALS double strand break repair premature aging replication stress EXO1 POL? translesion synthesis strand displacements G2-arrest DNA replication pattern SSB repair genome integrity G protein-coupled receptor kinase interacting protein 2 (GIT2) MMR replicative stress senolytics spacer interactome ATR-Chk1 DDR pathway C9orf72 replication fork restart translesion DNA synthesis DNA damage mismatch repair DNA replication stress DNA helicase Polymerase kappa DNA fiber assay H1299 cells TLS APE2 ageing cell death chromosome TopBP1 barley clock proteins post-translational modification 8-oxoG S phase ataxia telangiectasia mutated (ATM) G protein-coupled receptor (GPCR) Polymerase eta cancer G protein-coupled receptor kinase (GRK) helicase genomic instability Parkinson's disease nucleotide excision repair SupF |
| ISBN |
9783039213900
3039213903 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910367564903321 |
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Brosh Robert M
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| MDPI - Multidisciplinary Digital Publishing Institute, 2019 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Impaired Mitochondrial Bioenergetics under Pathological Conditions
| Impaired Mitochondrial Bioenergetics under Pathological Conditions |
| Autore | Lenaz Giorgio |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 online resource (460 p.) |
| Soggetto topico |
Biochemistry
Biology, life sciences Research & information: general |
| Soggetto non controllato |
aging
aging heart assembly factor ATP synthase ATP synthase/hydrolase atypical myopathy Barth syndrome Bcl-2 family bioenergetics C cancer cardiolipin cardiomyopathy cell culture cell signaling cellular bioenergetics cellular signaling complex I assembly complex I deficiency complex I structure complex III COVID-19 cristae cytochrome b diabetes Dilated Cardiomyopathy with Ataxia electron transport chain energy metabolism entorhinal cortex equine primary myoblasts exercise fatty acid oxidation fibroblasts frozen tissue G mutation glucagon heart failure high-resolution respirometry human disease immune system influenza innate immune response insulin Leigh syndrome leukocytes lipoxidation-derived damage m.3243A> m.8909T> mammalian complex I mathematical model MAVS MDA5 metabolic disease mitochondria mitochondrial disease mitochondrial diseases mitochondrial DNA mitochondrial dynamic mitochondrial dynamics mitochondrial dysfunction mitochondrial permeability transition pore mitochondrial proteostasis MT-ATP6 MTCYB mutations n/a NADH dehydrogenase nephropathy neurodegeneration oleate oxidative damage oxidative phosphorylation oxidative stress oxygen consumption palmitate pancreatic endocrine cells pet mutants platelets programmed cell death protein import respiratory chain respiratory complex assembly respiratory complexes respiratory supercomplexes respirometry RIG-I ROS RSV Saccharomyces cerevisiae SARS CoV-2 Sengers syndrome skeletal muscle supercomplexes supernumerary subunits toxicity assays viral infections yeast |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910585934503321 |
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Lenaz Giorgio
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Metabolomics in Neurodegenerative Disease
| Metabolomics in Neurodegenerative Disease |
| Autore | Green Brian |
| Pubbl/distr/stampa | MDPI - Multidisciplinary Digital Publishing Institute, 2020 |
| Descrizione fisica | 1 online resource (184 p.) |
| Soggetto topico | Biology, life sciences |
| Soggetto non controllato |
?-synuclein aggregates
13C-labeled succinate 1H NMR 6-OHDA age-related macular degeneration Alzheimer's disease bile acids biomarkers C. elegans cerebral ischemia cerebral palsy dementia with Lewy bodies direct mass spectrometry drusen endothelin-1 energy metabolism excitotoxicity fatty acid fatty acid metabolism GC-MS glutamic acid imaging mass spectrometry LC-MS lipidomics malonate mass spectrometry metabolic pathways metabolism metabolomics micro-dialysis midbrain mitochondrial dysfunction myo-inositol n/a natural product neurodegeneration Parkinson's disease Parkinson's disease dementia pathogenesis plasma prodromal Parkinson's disease reperfusion retinal pigment epithelium Streptomyces venezuelae subacute mild traumatic brain injury targeted mass spectrometry tricarboxylic acid cycle |
| ISBN | 3-03928-041-4 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910404087203321 |
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Green Brian
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| MDPI - Multidisciplinary Digital Publishing Institute, 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Mitochondria in Health and Diseases
| Mitochondria in Health and Diseases |
| Autore | Javadov Sabzali |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 |
| Descrizione fisica | 1 online resource (434 p.) |
| Soggetto topico | Medicine and Nursing |
| Soggetto non controllato |
2-oxoglutarate dehydrogenase
4-HNE adenine nucleotide translocase ADP/ATP carrier aging amino acid neurotransmitter ancient mutation antioxidant system antioxidants apoptosis BAX BCL-2 BKCa channels cardiolipin cardiomyocytes cardioprotection cerebellar amino acid metabolism cholangiocellular carcinoma colon complex I (CI) deficiency cyclosporin A cytoskeletal proteins DDE dentate granule cell development dextran DRP1 dsRNA electron and confocal microscopy electron tunneling (ET) energy metabolism epilepsy ERK1/2 ETC complexes fatty acid oxidation ferritin gemfibrozil GW9662 H9c2 cardiomyoblasts healthy cells heart hepatic fibrogenesis hepcidin high-fat diet hippocampus HtrA2/Omi human amniotic membrane human diseases hyperforin hypoglycemia hypoxia inflammation innate immunity inorganic phosphate interferon response intranuclear mitochondria ion homeostasis iron overload ischemia reperfusion injury JNK KmADP Langendorff LHON life span lipid droplet lipid handling liver LONP1 metabolome and proteome profiling mitochondria mitochondria bioenergetics mitochondria calcium buffering mitochondria permeability transition pore mitochondria: energy metabolism mitochondrial cell death mitochondrial connexin 43 mitochondrial dynamics mitochondrial dysfunction mitochondrial function mitochondrial gene expression mitochondrial homeostasis mitochondrial interactions mitochondrial permeability transition pores mitochondrial UCP2 morphology mtDNA mtDNA transcription mtRNA muscle aging myocardial neuron death neuroprotection oxidative phosphorylation oxidative stress perilipin 5 physical performance pilocarpine pioglitazone PKA plectin post-transcriptional mtRNA processing potassium channel pravastatin protein phosphatases pyruvate dehydrogenase pyruvate dehydrogenase kinase reactive oxygen species reactive oxygen species (ROS) reactive oxygen species stress redox state regeneration respirasome assembly respiratory supercomplexes ROS rosiglitazone seizure Siberian population signaling signaling pathways siRNA sodium dichloroacetate specific genetic background telomerase activity telomere length tensile strength transferrin tricarboxylic acid cycle tubulin beta TUNEL TZD uncoupling uncoupling protein ZIP |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557577203321 |
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Javadov Sabzali
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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