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AMP-Activated Protein Kinase Signalling
| AMP-Activated Protein Kinase Signalling |
| Autore | Neumann Dietbert |
| Pubbl/distr/stampa | MDPI - Multidisciplinary Digital Publishing Institute, 2019 |
| Descrizione fisica | 1 online resource (452 p.) |
| Soggetto topico | Biology, life sciences |
| Soggetto non controllato |
?-linker
?RIM 2-methoxyestradiol 3T3-L1 A769662 acetyl-CoA activation loop adaptive thermogenesis adenosine monophosphate-activated protein kinase adherent junctions adipocyte adipose tissue AICAR AID Akt AML AMP-activated protein kinase AMP-activated protein kinase (AMPK) AMPK AMPK kinase AS160 assisted reproduction techniques atrophy autophagy beiging CaMKK2 carrier catechol-O-methyltransferase CBS cellular energy sensing chromatin remodeling CML CMML co-expression CREB developmental origins of health and disease (DOHaD) dietary fatty acids differentiation DNA methylation endothelial cells endothelial function endothelial nitric-oxide synthase energy deficiency energy metabolism energy utilization epigenetics epithelial cells exercise fatty acid oxidation fiber-type food intake gestational diabetes mellitus glucose uptake glycogen glycogen storage disease HDAC4/5 HDACs heat shock protein hepatocyte hindlimb suspension histone modification host defense hypertension hypertrophy hypothalamus IL-1? Immediate early genes indirect calorimetry infection insulin signalling ionomycin KATs kidney disease lipid metabolism liver LKB1 macrophages MDCK MDS mechanical unloading medulloblastoma membrane membranes metabolic disease metabolic-inflammation metabolism microarrays mitochondria monocytes motility motor endplate remodeling mTOR mycobacteria MyHC I(?) n/a NAD+ nectin-afadin NLRP3 nutrient-sensing signals nutrigenomics nutrition oxidative stress p70S6K par complex peroxisome proliferator-activated receptor gamma coactivator 1-? (PGC1?) phenylephrine phosphorylation PKA preeclampsia pregnancy proteasome protein acetylation protein kinase B protein synthesis pump regrowth renin-angiotensin system resveratrol signaling sirtuin 1 (SIRT1) skeletal muscle soleus muscle soluble Adenylyl cyclase sonic hedgehog spermatozoa steatosis stress synaptic activation TAK1 TBC1D4 tight junctions transcription transporter ULK vasoconstriction vasodilation ZO-1 |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910346858503321 |
Neumann Dietbert
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| MDPI - Multidisciplinary Digital Publishing Institute, 2019 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Antioxidant Activity of Polyphenolic Plant Extracts
| Antioxidant Activity of Polyphenolic Plant Extracts |
| Autore | Stagos Dimitrios |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 online resource (388 p.) |
| Soggetto topico |
Biology, life sciences
Research and information: general |
| Soggetto non controllato |
AGN
almond skins alpha-amylase alpha-glucosidase Alzheimer's disease amino acids anthocyanin anthocyanins anti-inflammatory activity antibiofilm activity antidiabetic antimicrobial antimicrobial activity antioxidant antioxidant activities antioxidant activity antioxidant capacity antioxidants antioxidative effect Averrhoa bilimbi beneficial use bioavailability bixin Caco-2 cells caffeine Camellia sinensis cape floristic region catechin central composite design characterisation cornelian cherry cyanidin 3-glucoside cyanidin 3-rutinoside cytotoxicity diabetes diabetes mellitus Dialium indum digestive enzymes inhibitors DPPH effect of cooking encapsulation endothelial cells exocarp extraction FIR fish flavonoid flavonoids food matrices fruit vinegar gastrointestinal digestion GC-MS analysis gelatin glutathione green leafy vegetables H2O2 high performance liquid chromatography mass spectrometry (HPLC-MS) high performance liquid chromatography/diode array detector/mass spectrometry anthocyanins HPLC HPLC-ESI-HR-qTOF-MS/MS HPLC/ESI-MS HS-SPME/GC-MS human hydroxytyrosol insulin resistance Ladastacho Lamiaceae LC-QTOF-MS/MS liquid chromatography analysis maltodextrin mass spectrometry method validation molecular docking molecular docking analysis Morus alba) mulberry (Morus nigra myrtle n/a Olea europaea olive olive mill wastewater olive oil optimization Opuntia ficus-indica cladode organic acid organic acids Oxalidaceae oxidative stress oxygen radical absorbance capacity (ORAC) P. officinalis phenol compounds phenolic phenolic acids phenolic compounds phenolics phenols phytochemicals polyphenol polyphenol compounds polyphenols pomegranate proinflammatory cytokines properties Pyrocantha coccinea reactive oxygen species red-osier dogwood Rosa canina Rosa sempervivens rosemary rosemary extracts Rubus idaeus L. Salvia africana-lutea seed simple sugars spray drying tea tentative bioactive constituents terpenoids theaflavine transepithelial resistance (TEER) ultrasound-assisted extraction volatile compounds waste by-products whey protein xanthine oxidase α-amylase inhibition |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557728403321 |
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Stagos Dimitrios
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Arteriogenesis and Therapeutic Neovascularization
| Arteriogenesis and Therapeutic Neovascularization |
| Autore | Deindl Elisabeth |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 |
| Descrizione fisica | 1 online resource (220 p.) |
| Soggetto topico | Medicine |
| Soggetto non controllato |
A-to-I editing
activity-based benefits angiogenesis aortic disease arteriogenesis atherosclerosis blood flow recovery blood flow restriction capillary collateral artery growth collateral growth collateral network effect mechanism Egr-1 endothelial cells epitranscriptome ERK factor VII activating protease femoral artery ligation FGFR-1 GH and eNOS GHAS trial HABP2 hind limb ischemia hyperoxygenation IGF-I inflammation innate immunity isomiRs KCa3.1 KV1.3 lower extremity arterial disease m6A macrophages mast cell matrigel microRNA microRNA-212/132 n/a neo-vascularization neovascularization NO NOTCH oxidative stress and arterial inflammation paraplegia paraspinous compartment PDFG-R pericyte peripheral arterial disease potassium channel rAAV RNA methylation RNA modifications SMC proliferation spinal cord ischemia TAAA TLR2/6 training effects vascular biology vascular homeostasis VEGF vein graft disease VHL loss of function αSM-actin |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557495503321 |
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Deindl Elisabeth
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Drug Delivery of siRNA Therapeutics
| Drug Delivery of siRNA Therapeutics |
| Autore | Lamberti Gaetano |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 |
| Descrizione fisica | 1 online resource (288 p.) |
| Soggetto topico | Medicine |
| Soggetto non controllato |
AKT
amphiphilic dendrons angiogenesis antitumor effect aptamers asthma BCL2 BIRC5/survivin breast cancer cancer carbonate apatite cationic cholesterol derivative cationic liposome clinical trials covalent dendrimers delivery drug co-delivery drug delivery endoglin endothelial cells ERBB2 folate folate receptor gene knockdown gene silencing indocyanine green intracellular release iron oxide light-activated release lipid liposome liposomes magnetic nanoparticle methotrexate migration mixed micelles n/a NABDs nanoparticle nanoparticles nanovectors oligonucleotide delivery oral cancer ovarian cancer PAMAM dendrimers pegylation PEI peptide poly(ethylene) imine polyamine polyaspartamide polymer polyplexes proliferation RNA RNAi therapeutics self-assembling siRNA siRNA delivery STAT6 targeted delivery system tumor xenograft tumor-targeting tyrosine-modification VEGFA VEGFR1 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557498903321 |
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Lamberti Gaetano
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Embryo Implantation and Placental Development
| Embryo Implantation and Placental Development |
| Autore | Campagnolo Luisa |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 electronic resource (342 p.) |
| Soggetto topico |
Research & information: general
Biology, life sciences |
| Soggetto non controllato |
fetuin-A
GDM cell growth centrosome primary cilium autophagy implantation endometrium blastocyst embryo chorionic gonadotropin progesterone Notch cytokines placenta amino acid transporter mammalian target of rapamycin gestational diabetes trophectoderm cell proliferation let-7 miRNAs gene regulation fractalkine trophoblast bilaminar co-culture miRNA trophoblast cells ARID3B complex decidualization adverse pregnancy outcome preconception preimplantation genetic screening in-vitro fertilization biopsy euploid embryo pregnancy mosaicism development flow culture KIT receptor KITD816V placental development premature differentiation trophoblast stem cell trophoblast giant cell spongiotrophoblast invasion embryonic growth retardation Jag1 Dll4 endothelial cells decidua angiogenesis capillaries spiral arteries Stabilin-1 Stabilin-2 double knockout hemorrhage RNA-seq ChIP-seq enhancers transcription factors PLAGL1 tube formation blood vessel development PlGF Flt-1/VEGFR1 immune modulation human placenta lopinavir mitochondria Mfn2 UPR IRE1α placental dysfunction assisted reproduction techniques infertility preeclampsia intrauterine growth restriction trophoblast invasion sFLT-1 EGFL7 placenta-derived mesenchymal stromal cells mouse model |
| ISBN | 3-0365-5853-5 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910639986303321 |
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Campagnolo Luisa
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Emerging immune functions of non-hematopoietic stromal cells / / topic editors: Christopher G. Mueller, Paul Kaye, Mark C. Coles and Burkhard Ludewig
| Emerging immune functions of non-hematopoietic stromal cells / / topic editors: Christopher G. Mueller, Paul Kaye, Mark C. Coles and Burkhard Ludewig |
| Autore | Mark Christopher Coles |
| Pubbl/distr/stampa | Frontiers Media SA, 2014 |
| Descrizione fisica | 1 online resource (161 pages) : illustrations |
| Disciplina | 616.97 |
| Collana | Frontiers Research Topics |
| Soggetto topico |
Clinical Immunology
Medicine Health & Biological Sciences |
| Soggetto non controllato |
development
endothelial cells lymphoid tissue inflammation fibroblast reticular cells |
| ISBN | 9782889193622 (ebook) |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910137235403321 |
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Mark Christopher Coles
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| Frontiers Media SA, 2014 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Endothelial Dysfunction: From Pathophysiology to Novel Therapeutic Approaches
| Endothelial Dysfunction: From Pathophysiology to Novel Therapeutic Approaches |
| Autore | Jeon Byeong Hwa |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 online resource (368 p.) |
| Soggetto topico |
Biotechnology
Technology: general issues |
| Soggetto non controllato |
ADMA
aerobic exercise aldehyde dehydrogenase-2 angiogenesis APE1/Ref-1 ApoE knockout mouse arginine arginine paradox atherosclerosis atorvastatin BH4 blood pressure cardiovascular disease cardiovascular diseases cardiovascular risk factors chronic kidney disease chronic venous insufficiency CKD compound 9 COVID-19 CV risk diabetes dietary supplements dyslipidemia electronegative LDL electronegative low-density lipoprotein EndoMT endothelial cell endothelial cell dysfunction endothelial cells endothelial disfunction endothelial dysfunction endothelial to mesenchymal transition endothelium eNOS uncoupling epigenetic factors epigenetics essential hypertension galectin-3 glycated HDL glycated LDL glycated lipoproteins glycolysis healing heart failure HIF-1α high-fat diets hyperglycemia hyperphosphatemia hypertension inflammageing inflammation insulin resistance ischemia L-arginine L5 LDL LDL(-) LDL(−) lectin-like oxLDL receptor-1 low-level laser therapy LOX-1 lung disease macrophage polarity macrophages metabolism metformin molecular mechanisms MRI (magnetic resonance imaging) myocardial infarction n/a NADPH nargenicin A1 neurovascular disease neutrophil/lymphocyte ratio nitric oxide oxidative stress oxidized LDL oxLDL pathological angiogenesis PCSK9 peripheral artery disease phototherapy plaque burden prolyl oligopeptidase (POP) pulmonary fibrosis pulmonary hypertension serological biomarkers serum γ-glutamyltransferase subcellular localization TGF-β therapeutic approaches tumor microenvironment uremic toxins vascular calcification vascular disease vascular inflammation vascular smooth muscle cells vasoactive factors VCAM-1 VEGF VEGFR2 VSMCs |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | Endothelial Dysfunction |
| Record Nr. | UNINA-9910566471803321 |
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Jeon Byeong Hwa
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Genetics and Genomics of Pulmonary Arterial Hypertension
| Genetics and Genomics of Pulmonary Arterial Hypertension |
| Autore | Southgate Laura |
| Pubbl/distr/stampa | Basel, : MDPI Books, 2022 |
| Descrizione fisica | 1 electronic resource (188 p.) |
| Soggetto topico |
Research & information: general
Biology, life sciences Genetics (non-medical) |
| Soggetto non controllato |
pulmonary arterial hypertension
massive parallel sequencing NGS digenic inheritance and genetics BMPR2 promoter pathogenic variant heritable pulmonary arterial hypertension genetic analysis NGS gene panel BMPR2 TBX4 GDF2 EIF2AK4 genomics pediatrics lung disease endothelial cells smooth muscle cells DNA damage DNA repair expression quantitative trait locus eQTL blood genetics exome sequencing molecular genetics paediatrics bone morphogenetic protein receptor type 2 heritable familial estrogen estradiol penetrance gender PAH forward phenotyping forward genetics reverse genetics reverse phenotyping intermediate phenotypes whole-genome sequencing epigenetic inheritance genetic heterogeneity phenotypic heterogeneity pulmonary hypertension bone morphogenetic protein receptor 2 signaling repurposed drugs pharmaceuticals miRNA clinical trials |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910595078603321 |
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Southgate Laura
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| Basel, : MDPI Books, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Glutathione: Chemistry and Biochemistry
| Glutathione: Chemistry and Biochemistry |
| Pubbl/distr/stampa | MDPI - Multidisciplinary Digital Publishing Institute, 2023 |
| Descrizione fisica | 1 online resource (212 p.) |
| Soggetto topico |
Biology, life sciences
Research and information: general |
| Soggetto non controllato |
angiotensin-converting enzyme
anticancer drugs apoptosis autoimmune diseases bioactivation brain cell cell injury chalcone cyclophosphamide cysteine detoxification DFT diastereoselective addition diode array detector endothelial cells fluorescence probes GCLc glutaredoxin glutathione glutathione enzyme glutathione system glutathione-S-transferase glutathionylation GSH GSS GSSG iron iron-sulfur cluster ischemia liquid chromatography M06-2X/6-311++G(d,p) mechanisms of glutathione conjugation reaction Michael addition molecular docking n/a nanotoxicity nitrosoglutathione oxidative stress pharmacokinetics physicochemical properties polymerized whey protein polymorphism reactive oxygen species redox homeostasis redox potential redox-regulation S-glutathionylation S-nitrosylation sulodexide supramolecular arrangement thiols toxicity |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | Glutathione |
| Record Nr. | UNINA-9910743269903321 |
| MDPI - Multidisciplinary Digital Publishing Institute, 2023 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Hereditary Hemorrhagic Telangiectasia : Recent Advances and Future Challenges
| Hereditary Hemorrhagic Telangiectasia : Recent Advances and Future Challenges |
| Autore | Mager Hans-Jurgen |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 online resource (228 p.) |
| Soggetto topico | Research and information: general |
| Soggetto non controllato |
activin receptor-like kinase 1 (ALK1)
activin-receptor-like kinase 1 ACVRL1 ALK1 angiogenesis antiangiogenic properties anticoagulants antiplatelets antithrombotic therapy arteriovenous malformation arteriovenous malformation (AVM) arteriovenous malformations (AVMs) AVM bazedoxifene bevacizumab biomarker biomarkers bleeding bone morphogenetic protein (BMP) catheter based embolization therapy cell adhesion cerebral ischemic lesions contrast enhanced magnetic resonance angiography endoglin Endoglin endothelial cells ENG epistaxis epistaxis severity score etamsylate FK506 gastrointestinal bleeding genetic disease genotype-phenotype correlation guidelines hereditary hemorrhagic hereditary hemorrhagic telangiectasia Hereditary hemorrhagic telangiectasia Hereditary Hemorrhagic Telangiectasia hereditary hemorrhagic telangiectasia (HHT) hereditary hemorrhagic telangiectasia (HHT), second-hit hereditary hemorrhagic telangiectasia/HHT/osler's disease HHT inflammation life expectancy liver long non-coding RNAs mechanical damage microRNA microRNAs MRI N-acetylcysteine nasal endoscopy nasal ointment non-coding RNAs nosebleeds Osler-Weber-Rendu pediatrics plasma propranolol propranolol gel pulmonary arteriovenous malformation pulmonary arteriovenous malformations raloxifene rare disease rare diseases safety screening shear stress Smad pathway Smad4 SMAD4 somatic mutation sun-induced trauma survival tacrolimus telangiectases telangiectasia telangiectasis tranexamic acid transcatheter embolotherapy transforming growth factor beta (TGF-β) transforming growth factor-beta (TGF-β) ultrasound vascular endothelial growth factor (VEGF) vascular injury vascular malformations |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | Hereditary Hemorrhagic Telangiectasia |
| Record Nr. | UNINA-9910557578003321 |
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Mager Hans-Jurgen
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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