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Antitumoral Properties of Natural Products
| Antitumoral Properties of Natural Products |
| Autore | Fabiani Roberto |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 |
| Descrizione fisica | 1 electronic resource (344 p.) |
| Soggetto topico |
Research & information: general
Biology, life sciences |
| Soggetto non controllato |
cytotoxic activity
NCI-60 cancer cell line pristimerin Salacia crassifolia Celastraceae Brazilian Cerrado biome Salacia elliptica Cheiloclinium cognatum Plenckia populnea Aspergillus fumigatus Cordyceps sinensis isochromanes chiral resolution ECD calculation cytotoxicity coronarin D JNK osteosarcoma Zeylenone gastric cancer invasion migration apoptosis anti-cancer agents anthraquinones glycosyltransferase Dendrobium officinale structure elucidation anti-tumor activity plantation mode AR Ganoderma tsugae lipogenesis prostate cancer SREBP-1 ursolic acid betulinic acid triterpenoids necrotic quercetin quercetagetin patuletin lichen secondary metabolites tumidulin stemness potential colorectal cancer cells oncogene transcriptional regulation neferine FAK/S6K1 autophagy human neuroblastoma cells natural yellow Monascus pigments water-soluble antioxidation MCF-7 cells phloretin cell proliferation inflammation glucose uptake Catalpa speciosa Taxus cuspidata Magnolia acuminata phenols antioxidants anticancer Colocasia esculenta food bioactive tarin stable nanocapsules entrapment efficiency no-toxicity preclinical tests antitumoral activity chemotherapeutic adjuvant grape leaves ASE TP Antioxidant activities Antiproliferative pro-apoptotic effects Gene expression Nutraceuticals Cucurbitacin B gefitinib-resistant NSCLC EGFR lysosomal degradation CIP2A zerumbone cancer NF-κB IL-6/JAK2/STAT3 Akt FOXO1 multiple myeloma quality control naringenin flavonoids traditional preparation cancer stem cells phytochemicals plant-derived foods fruit vegetable cell signaling Artemisia absinthium endoplasmic reticulum stress mitochondrial-dependent pathway melanoma bee venom melittin temozolomide AKT MAPK antrodin C mTOR metabolic stability capsazepine inflammatory diseases ROS TRPV1 PI3K/AKT/mTOR CLE-10 LC3 MDA-MB-231 lactoferrin hydrolysate copper manganese gastric cancer cells anti-cancer activity molecular mechanism natural product alkaloids cephalotaxine protein synthesis inhibition antiproliferation agents folk medicine DLD-1 cells doxorubicin chemotherapy drug resistance CrataBL glioblastoma mesenchymal stem cells microenvironment plant lectin protease inhibitor cryptolepine neocryptolepine isocryptolepine antiproliferative activity structure activity relationships Licochalcone A ATM-Chk2 13-ethylberberine mitochondrial ROS RT-R breast cancer cells diallyl disulfide PI3K/Akt/mTOR pathway Pulsatilla saponin D SB365 glioblastoma multiforme autophagic flux inhibition lysosomal membrane permeabilization mitochondrial membrane potential CLEFMA p38 proanthocyanins TNF-α lung adenocarcinoma natural compounds cervical cancer cell cycle arrest dicentrine metastasis glioma semi-synthetic derivative ingenol Euphorbia tirucalli protein kinase C seaweed porphyran carrageenan anti-cancer natural products |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557419703321 |
Fabiani Roberto
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Antitumoral Properties of Natural Products : Volume 2
| Antitumoral Properties of Natural Products : Volume 2 |
| Autore | Fabiani Roberto |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 |
| Descrizione fisica | 1 electronic resource (300 p.) |
| Soggetto topico |
Research & information: general
Biology, life sciences |
| Soggetto non controllato |
cytotoxic activity
NCI-60 cancer cell line pristimerin Salacia crassifolia Celastraceae Brazilian Cerrado biome Salacia elliptica Cheiloclinium cognatum Plenckia populnea Aspergillus fumigatus Cordyceps sinensis isochromanes chiral resolution ECD calculation cytotoxicity coronarin D JNK osteosarcoma Zeylenone gastric cancer invasion migration apoptosis anti-cancer agents anthraquinones glycosyltransferase Dendrobium officinale structure elucidation anti-tumor activity plantation mode AR Ganoderma tsugae lipogenesis prostate cancer SREBP-1 ursolic acid betulinic acid triterpenoids necrotic quercetin quercetagetin patuletin lichen secondary metabolites tumidulin stemness potential colorectal cancer cells oncogene transcriptional regulation neferine FAK/S6K1 autophagy human neuroblastoma cells natural yellow Monascus pigments water-soluble antioxidation MCF-7 cells phloretin cell proliferation inflammation glucose uptake Catalpa speciosa Taxus cuspidata Magnolia acuminata phenols antioxidants anticancer Colocasia esculenta food bioactive tarin stable nanocapsules entrapment efficiency no-toxicity preclinical tests antitumoral activity chemotherapeutic adjuvant grape leaves ASE TP Antioxidant activities Antiproliferative pro-apoptotic effects Gene expression Nutraceuticals Cucurbitacin B gefitinib-resistant NSCLC EGFR lysosomal degradation CIP2A zerumbone cancer NF-κB IL-6/JAK2/STAT3 Akt FOXO1 multiple myeloma quality control naringenin flavonoids traditional preparation cancer stem cells phytochemicals plant-derived foods fruit vegetable cell signaling Artemisia absinthium endoplasmic reticulum stress mitochondrial-dependent pathway melanoma bee venom melittin temozolomide AKT MAPK antrodin C mTOR metabolic stability capsazepine inflammatory diseases ROS TRPV1 PI3K/AKT/mTOR CLE-10 LC3 MDA-MB-231 lactoferrin hydrolysate copper manganese gastric cancer cells anti-cancer activity molecular mechanism natural product alkaloids cephalotaxine protein synthesis inhibition antiproliferation agents folk medicine DLD-1 cells doxorubicin chemotherapy drug resistance CrataBL glioblastoma mesenchymal stem cells microenvironment plant lectin protease inhibitor cryptolepine neocryptolepine isocryptolepine antiproliferative activity structure activity relationships Licochalcone A ATM-Chk2 13-ethylberberine mitochondrial ROS RT-R breast cancer cells diallyl disulfide PI3K/Akt/mTOR pathway Pulsatilla saponin D SB365 glioblastoma multiforme autophagic flux inhibition lysosomal membrane permeabilization mitochondrial membrane potential CLEFMA p38 proanthocyanins TNF-α lung adenocarcinoma natural compounds cervical cancer cell cycle arrest dicentrine metastasis glioma semi-synthetic derivative ingenol Euphorbia tirucalli protein kinase C seaweed porphyran carrageenan anti-cancer natural products |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | Antitumoral Properties of Natural Products |
| Record Nr. | UNINA-9910557531303321 |
|
Fabiani Roberto
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||
| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Emerging Paradigms in Insulin Resistance
| Emerging Paradigms in Insulin Resistance |
| Autore | Burke Susan J |
| Pubbl/distr/stampa | MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 electronic resource (190 p.) |
| Soggetto topico |
Research & information: general
Biology, life sciences |
| Soggetto non controllato |
epicardial adipose tissue
hypertrophy of adipocytes CAD severity adipokines insulin resistance insulin-degrading enzyme pancreas liver insulin receptor glucose transporters acute intermittent porphyria carbohydrate loading therapy hyperinsulinemia fast-acting insulin experimental liver-targeted insulin hyperinsulinaemia osteocalcin beta-hydroxybutyrate phenotype stages serotonin glucagon-like peptide-1 glucagon type 2 diabetes hyperglycaemia apoptosis endoplasmic reticulum stress glucosamine pancreatic β-cell dysfunction ovariectomy raloxifene Negr1 obesity metabolic disease metabolomics glucose intolerance genetic models beta hydroxybutyrate osteoporosis fragility fractures bone mineral density osteocalin vitamin D collagen hydroxyapatite diabetes inflammation thiazolidinedione |
| ISBN | 3-0365-5366-5 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910619471703321 |
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Burke Susan J
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| MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Marine Anti-inflammatory and Antioxidant Agents 2021
| Marine Anti-inflammatory and Antioxidant Agents 2021 |
| Autore | Degl'Innocenti Donatella |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 electronic resource (172 p.) |
| Soggetto topico |
Medicine
Pharmacology |
| Soggetto non controllato |
algal biome
polysaccharides bioactive entities engineered cues therapeutic attributes inflammatory bowel disease microalgae Tisochrysis lutea fucoxanthin inflammation RAW 264.7 microRNA astaxanthin dendritic cells sepsis immune dysfunction lipopolysaccharide oxidative stress Ulva lactuca polysaccharide D-galactose kidney oyster peptides spermatogenesis apoptosis hormone testis C-phycoerythrin Phormidium persicinum acute kidney injury mercury endoplasmic reticulum stress bioactive peptide cytoprotective endothelial dysfunction blue mussel acute liver injury ferroptosis oyster peptide pyroptosis zooplankton natural products antioxidant transcriptome mining |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910566461803321 |
|
Degl'Innocenti Donatella
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Nutrition and Eye Health
| Nutrition and Eye Health |
| Autore | Downie Laura |
| Pubbl/distr/stampa | MDPI - Multidisciplinary Digital Publishing Institute, 2020 |
| Descrizione fisica | 1 electronic resource (242 p.) |
| Soggetto non controllato |
polyphenols
crocin chyrsin glaucoma dietary assessment photoreceptor degeneration dry eye RR-zeaxanthin nutritional supplements drug discovery corneal neovascularization (CNV) AMD dietary antioxidants micronutrients age-related macular degeneration preclinical models lenses microvascular lesions cyclooxigenase-2 (COX-2) angiogenesis fish oil macrophage anti-oxidant vascular endothelial growth factor (VEGF) rosmarinic acid visual cycle diabetic retinopathy lutein gut-retina axis light damage crocetin supplements clinical practice guidelines nutrition light eye disease dietary habits flavonoids phytoconstituents saffron carotenoids fatty acid electroretinography lens advanced glycation end products interleukin-1? (IL-1?) mesozeaxanthin (RS zeaxanthin) endoplasmic reticulum stress omega-3 polyunsaturated fatty acids clinical survey corneal chemical burn reduced glutathione omega-3 AGREE II retina inflammation anti-inflammatory retinal pigment epithelium diet Lactobacillus paracasei KW3110 Crocus Sativus L. saponins cataract CODS neoangiogenesis estrogen-deficient rats food frequency questionnaire gut microbiota antioxidant supplements sinapic acid personalised medicine systematic reviews nuclear factor-kappaB (NF-?B) diabetes Cucurbita argyrosperma oxidative stress endoplasmic reticulum |
| ISBN | 3-03921-991-X |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910372786403321 |
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Downie Laura
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| MDPI - Multidisciplinary Digital Publishing Institute, 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Physiological and Pathological Role of ROS: Benefits and Limitations of Antioxidant Treatment
| Physiological and Pathological Role of ROS: Benefits and Limitations of Antioxidant Treatment |
| Autore | Di Meo Sergio |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 |
| Descrizione fisica | 1 electronic resource (236 p.) |
| Soggetto topico |
Research & information: general
Biology, life sciences |
| Soggetto non controllato |
CTCL
apoptosis cell viability c-FLIP XIAP artemisinin SH-SY5Y cells hippocampal neurons H2O2 AMPK pathway atherosclerosis sphingomyelin synthase 2 endothelial dysfunction endoplasmic reticulum stress β-catenin insulin resistance cancer cardiovascular disease neurodegenerative disorders exercise mitochondria oxidative stress PGC-1 Nrf2 UCPs ROS light DNA damage evolution D-box cavefish Spalax trimethylamine N-oxide cardiomyocytes cardiotoxicity mitochondrial membrane potential CORM-2 NADPH oxidase AP-1 HO-1 Renal cell carcinoma (RCC) reactive oxygen species (ROS) glutathione (GSH) metabolism cancer therapy clear cell RCC papillary RCC chromophobe RCC sarcopenia reactive oxygen species redox signaling antioxidant supplementation protein aggregation redox proteinopathy peroxiredoxins tumorigenesis ROS scavengers |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | Physiological and Pathological Role of ROS |
| Record Nr. | UNINA-9910557430503321 |
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Di Meo Sergio
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Plant Natural Products for Human Health
| Plant Natural Products for Human Health |
| Autore | Zhang Hongjie |
| Pubbl/distr/stampa | MDPI - Multidisciplinary Digital Publishing Institute, 2019 |
| Descrizione fisica | 1 electronic resource (514 p.) |
| Soggetto non controllato |
PhGs
bitter orange immunomodulator A549 cells bergapten triptolide BMP/Smad phytochemicals antioxidant enzymes kumquat MTT assay HepaRG cells human health nanoparticles dendritic cells drug discovery biofilm catechin antitubercular activity Panax notoginseng saponins animals mouse-hair growth A? curcumin WNT/?-catenin copaiba AD Plasmodium parasites traditional medicine procyanidin A2 PET inhibition rheumatoid arthritis cannabinoid type 1 receptor iridoids inflammatory bowel disease acute liver injury human-hair-follicle dermal papilla cells Neuroprotective dihydromyricetin AMPK thromboembolism ginseng drug design and development endoplasmic reticulum stress mitogen-activated protein kinase Nrf2 prenylated flavonoids inflammation preclinical studies plants dietary supplements Glycyrrhiza uralensis aspirin Tripterygium wilfordii P. eryngii reperfusion ethnopharmacology glucans innovation hpatoprotection hinokitiol phytocannabinoid antistaphylococcal activity Shh/Gli green tea sesquiterpenoids adjuvant-induced arthritis yuzu hepatotoxicity p53/Bax Keap1 nuclear factor-kappaB oxidative stress pharmacokinetic study cinnamamides toxicity APAP Astragali Radix computational softwares plant natural product onion anti-malaria activity lipogenesis bleeding time diterpenoids Penthorum chinense Pursh myocardial hypertrophy automation adjuvant grapefruit melanoma cell essential oil sweet orange Amadori rearrangement compounds heme oxygenase global health calorie restriction bergamot liposomes EGCG celastrol herb–drug interactions cannabigerol anti-inflammation OH· free radical molecular targets gluconeogenesis microbiome SIRT1 fucoidan heart PC12 cells acetaminophen omics time-kill assay arthritis lychee seed bioinformatics structure–activity relationship precision medicine orange petitgrain immune modulation antiproliferation flavonoids scoulerine oleoresin triterpenic acids Cannabis sativa NAFLD biological activity differentiation oxygen consumption rate mitochondrial bioenergetics neroli apoptosis targeted delivery platelet activation protein kinase heat-process hepatic steatosis hyperglycemia natural products lemon genistein neuroinflammation astragaloside IV cytoxicity flavonoid paracetamol medicinal plants insulin resistance resveratrol mandarin garlic TGF-? morin hydrate sirtuin 3 MMPs gomisin N lime Ziziphus jujuba antifungal activity ischemia migration caspases small molecules |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910346688103321 |
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Zhang Hongjie
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| MDPI - Multidisciplinary Digital Publishing Institute, 2019 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Protective and Detrimental Role of Heme Oxygenase-1
| Protective and Detrimental Role of Heme Oxygenase-1 |
| Autore | Sorrenti Valeria |
| Pubbl/distr/stampa | MDPI - Multidisciplinary Digital Publishing Institute, 2019 |
| Descrizione fisica | 1 electronic resource (220 p.) |
| Soggetto non controllato |
coronary artery disease
glucocorticoid receptor antigen presentation analgesia chemotherapy locus coeruleus Sirtuin 1 thiol groups Heme Oxygenase-1 Betula etnensis Raf heme oxygenase 1 tolerance heme oxygenase atherosclerosis nitric oxide caloric restriction liver carbon monoxide ER stress heme oxygenase-1 mineralocorticoid receptor Type 1 diabetes mellitus (T1D) Gamma-Glutamyl-Cysteine Ligase (GGCL) angiotensin II bilirubin Heme oxygenase-1 (HO-1) inducers Inducible nitric oxide synthase (iNOS) HO-1 activity inhibitor ferroptosis Myristica fragrans kernels glutathione high-pressure gas apoptosis HO-1 diabetes mellitus Caffeic acid phenethyl ester (CAPE) carotid plaque ischemia-reperfusion injury ANTIGEN presenting cell LPS endoplasmic reticulum stress hemoglobin Pancreatic oxidative damage Colon cancer inflammation reactive oxygen species inflammatory pain paracetamol cardiomyopathy heme oxigenase-1 adipocytes sirtuin 1 peripheral artery disease PGC-1? heme Reactive oxygen species (ROS) metformin GR prostate cancer NF-?B hyperbilirubinemia iron Tet-ON system lung preservation oxidative stress Gunn rats Dimethylarginine dimethylaminohydrolase-1 (DDAH-1) |
| ISBN | 3-03921-807-7 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910367746303321 |
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Sorrenti Valeria
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| MDPI - Multidisciplinary Digital Publishing Institute, 2019 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Rare Respiratory Diseases: A Personal and a Public Health Problem
| Rare Respiratory Diseases: A Personal and a Public Health Problem |
| Autore | Dasí Francisco |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 electronic resource (242 p.) |
| Soggetto topico |
Medicine
Pharmacology |
| Soggetto non controllato |
standard diagnosis
reference centres clinical presentation cilia primary ciliary dyskinesia alpha-1 antitrypsin deficiency rare respiratory diseases Mycobacterium avium Mycobacterium intracellulare nodular bronchiectasis non-tuberculous mycobacteria pulmonary aspergillosis rare pulmonary disease miRNA expression exhaled breath condensate sputum severity pulmonary exacerbation alpha1 antitrypsin deficiency augmentation therapy replacement therapy rare diseases gene therapy alpha-1-antitrypsin deficit cystic fibrosis neonatal respiratory distress laterality defect orphan diseases PCD immunofluorescence antibody ALI culture bio-resource primary nasal epithelium diagnostics Alpha-1 antitrypsin deficiency liver disease glutamate-oxaloacetate transaminase glutamate-pyruvate transaminase gamma-glutamyl transpeptidase resilience active lifestyle stress levels infection control measure self-quarantine flow cytometry nasal epithelium oxidative stress reactive oxygen species endoplasmic reticulum stress antioxidant therapies idiopathic pulmonary fibrosis chronic obstructive pulmonary disease bronchiectasis asthma emphysema alpha1-antitrypsin deficiency transient elastography |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | Rare Respiratory Diseases |
| Record Nr. | UNINA-9910566479403321 |
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Dasí Francisco
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Ubiquitination in Health and Diseases
| Ubiquitination in Health and Diseases |
| Autore | Ishigami Tomoaki |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 electronic resource (292 p.) |
| Soggetto topico |
Humanities
Social interaction |
| Soggetto non controllato |
deubiquitinase
degradation therapeutic target cancer hematopoiesis hematopoietic stem cells immune response regulation of gene expression ubiquitin system genetic diseases ubiquitin ligase deubiquitinases monoubiquitin signaling vesicular trafficking protein complex formation inflammation inhibitor innate immune interferon LUBAC NF-κB ubiquitin Parkinson’s disease dopa-responsive dystonia tyrosine hydroxylase α-synuclein fatty acid-binding protein 3 ubiquitination proteasomal degradation ubiquitin-proteasome system mitochondria E3 ubiquitin ligase MITOL/MARCH5 salt-sensitive hypertension Nedd4L/Nedd4-2 epithelial sodium channel aldosterone sensitive distal nephron excitation-transcription coupling RNF183 RNF186 RNF182 RNF152 RING finger mTOR endoplasmic reticulum stress osmotic stress ubiquitin code virus infection virus-host interaction tau protein semisynthesis disulfide-coupling polyubiquitin fibrils aggregation neurodegeneration deubiquitination inhibitors protein quality control proteolysis protein stabilization regulatory T cells mesenchymal stem cell cortical bone derived stem cell myocardial infarction blood pressure renal salt reabsorption vascular function ubiquitin proteasome system ubiquitin–proteasome pathway cilia ciliogenesis differentiation proliferation ciliopathy E3s DUBs UPS neurodegenerative disease immune-related diseases |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557356403321 |
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Ishigami Tomoaki
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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