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Clinical Paths for Soluble Epoxide Hydrolase Inhibitors
| Clinical Paths for Soluble Epoxide Hydrolase Inhibitors |
| Autore | Imig John D |
| Pubbl/distr/stampa | Frontiers Media SA, 2020 |
| Descrizione fisica | 1 online resource (197 p.) |
| Soggetto topico |
Pharmacology
Science: general issues |
| Soggetto non controllato |
eicosanoids
heart disease inflammation kidney disease neurological diseases oxylipins pain |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557211503321 |
Imig John D
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| Frontiers Media SA, 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Emerging Role of Lipids in Metabolism and Disease
| Emerging Role of Lipids in Metabolism and Disease |
| Autore | Pallottini Valentina |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 online resource (308 p.) |
| Soggetto topico | Medicine |
| Soggetto non controllato |
acid sphingomyelinase
adiponectin adipose tissue angiogenesis atherosclerosis ATM autotaxin BDNF BET proteins brain breast cancer breast reconstruction cardiovascular disease cell proliferation cell signaling cholesterol Cholesterol chronic inflammation diabetes mellitus DNA damage response double strand breaks eicosanoids endothelial cell epicardial fat thickness epigenetics epinephrine fatty acid Fatty acids female frontal cortex G-protein coupled receptors gender glyceride haptoglobin high-cholesterol diet high-density lipoprotein high-sensitivity c-reactive protein hippocampus HMGCR hyperglycemia ionizing radiation ischemia ischemic stroke JQ1 LDLr leptin lipid lipid droplets lipid mediators Lipid mediators lipid metabolism lipid metabolism diseases lipid storage diseases Lipids lipocalin lipolysis lipophagy Lipophagy lipoproteins liver lysocardiolipin acyltransferase lysophosphatidic acid metabolic reprogramming metabolic stress metabolism mTORC1 mutations neutral sphingomyelinase nuclear sphingolipids oral drug absorption oxidative stress oxidized phospholipids p53 pathology phosphatidylinositol 4,5-bisphosphate phospholipase A2 (PLA2) phospholipase C phospholipase D phospholipid polyunsaturated fatty acids prodrug prostaglandins pulmonary fibrosis radiation SOD sphingolipids Sphingolipids sphingomyelin metabolism sphingosine kinase 1 sphingosine-1-phosphate SREBP steroid synaptic proteins TFEB TMEM97 visceral fat thickness |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557800303321 |
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Pallottini Valentina
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Integrative Multi-Omics in Biomedical Research
| Integrative Multi-Omics in Biomedical Research |
| Autore | Gerner Christopher |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 online resource (178 p.) |
| Soggetto topico |
Biology, life sciences
Research & information: general |
| Soggetto non controllato |
acute myeloid leukemia
analysis flow anti-angiogenesis ATRA Barrett's esophagus batch variations bioinformatics cardiac metaplasia cGAS cheminformatics curcumin DNA sensing eicosanoids endometriosis esophageal adenocarcinoma exercise fetal calf serum heart HL-60 cell line host-pathogen interactions IFI16 induced differentiation inflammation innate immunity key molecules label-free method for drugs lipid lipidomics machine learning macrophages mass spectrometry mechanism of action metabolomics microbiota multi-omics multi-omics analysis myocardial infarction (MI) n/a natural products peroxisomes planned myocardial infarction (PMI) post-translational modifications protein interactions proteome proteomics receptor tyrosine kinases regulatory pathway modelling secretome SRM study design target identification target validation transcription factors transcriptome transcriptomics virus-host interactions |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557769003321 |
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Gerner Christopher
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Oxidative Stress in Diabetic Retinopathy
| Oxidative Stress in Diabetic Retinopathy |
| Autore | Ortega Ángel Luis |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 online resource (322 p.) |
| Soggetto topico | Medicine |
| Soggetto non controllato |
aging
angiogenesis antioxidant antioxidants apoptosis aqueous humor ascorbic acid astaxanthin biomarkers biomarkers of diabetic retinopathy blood-retinal barrier carotenoid Cinnamomi Ramulus CPA4-1 cyclooxygenase Cytochrome P450 db/db mice diabetes mellitus diabetic retinopathy diabetic retinopathy (DR) docosahexaenoic acid (DHA) eicosanoids eicosapentaenoic acid (EPA) epiretinal membrane extracellular vesicles fenofibrate free radicals GLP-1 glycation glyoxalase HDAC6 high-mobility group box 1 (HMGB1) human retina hyperglycemia inflammation inflammatory pathways internal limiting membrane lipoxygenase macular hole metabolic memory miRNA mitochondria n/a novel therapies Nrf2 occludin oxidative stress Paeoniae Radix photoreceptor photoreceptor cells PI3K proliferative diabetic retinopathy reactive oxygen species redox retinal disease retinal endothelial cell senescence retinal endothelial cells retinal pigment epithelium superoxide dismutase tear film thioredoxin tubastatin A vitamin D vitreoretinal surgery vitreous humor |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557134903321 |
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Ortega Ángel Luis
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Placental Related Disorders of Pregnancy
| Placental Related Disorders of Pregnancy |
| Autore | Mistry Hiten D |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 electronic resource (378 p.) |
| Soggetto topico |
Medicine
Physiology |
| Soggetto non controllato |
low-dose aspirin
preeclampsia placenta eicosanoids sphingolipids thromboxane prostacyclin isoprostanes neutrophils protease-activated receptor 1 cold shock protein intrauterine growth restriction placentation apoptosis NF-κB hypertension in pregnancy angiogenesis endothelial function oxidative stress antioxidants post-maturity senescence pre-eclampsia renin-angiotensin system megalin proton pump inhibitors telomere shortening prenatal depression sex differences flow culture system explant culture under flow placental insufficiency SPINT2/HAI-2 foetal growth restriction small for gestational age placentome pregnancy nutrient restriction gene expression transcriptome spontaneous preterm birth bioenergetic metabolism interactome fetal sex disparity CD24 cytotrophoblast syncytiotrophoblast immunohistochemistry quantitative polymerase chain reaction (qPCR) immune tolerance inflammation cytokines adipokines antimicrobial peptides metabolic stress IGF-I insulin lactotroph hormones decidual reaction fetal membranes placental hormones primates uterine spiral artery uterine NK cell chorionic somatomammotropin blood flow nutrient uptake uterus ERAP2 trophoblast cells RNA sequencing differentially expressed genes congenital heart disease hand1 vascular development intrahepatic cholestasis of pregnancy human placenta bile acids transporters pregnancy complications metabolism glycolysis mitochondrial respiration placental metabolism trophoblast glycolysis trophoblast mitochondrial respiration sexual dimorphism Interleukin-15 CD122 natural killer cells macrophages trophoblast Irisin TRPV6 calcium transport skeletal dysplasia serine proteases subunit assembly transient receptor potential antioxidant capacity decidua fetal growth restriction KEAP1 NRF2 |
| ISBN | 3-0365-5899-3 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910639995303321 |
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Mistry Hiten D
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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The Role of PPARs in Disease
| The Role of PPARs in Disease |
| Autore | Wagner Nicole |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 online resource (274 p.) |
| Soggetto topico |
Medicine and Nursing
Physiology |
| Soggetto non controllato |
addiction
adipogenesis AKI alcohol Alzheimer's Alzheimer's disease (AD) angiogenesis animal models cancer cellular metabolism cilia CKD cognition coronary artery CYP450 cystogenesis dominant-negative isoform eicosanoids endothelial cells fatty acids fetal programming fibrosis folate growth suppressors human studies hypertrophic adipocytes hypertrophic obesity immortality immune system in vitro adipocytes inflammation inherited metabolic disorders insulin-resistance kidney ligand ligands lipidomics lipids metabolic syndrome metastasis metastasis formation modulators nephron nicotine non-alcoholic fatty liver disease (NAFLD) non-alcoholic steatohepatitis (NASH) nuclear receptors obesity opioids peroxisome proliferator activated receptors peroxisome proliferator-activated receptor peroxisome proliferator-activated receptor-γ coactivator-1α peroxisome proliferator-activated receptors (PPARs) peroxisome-proliferator activated receptors PGC-1α, disease pharmacology PKD PPAR PPARG isoforms PPARG splicing PPARs PPARα proliferation psychostimulants resistance to cell death risk factors RNA sequencing sex Sirtuin1 synthetic agonists therapy toxicology tumor angiogenesis tumor progression vascular vitamin B12 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910566482503321 |
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Wagner Nicole
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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