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Antitumor and Anti-HIV Agents from Natural Products
| Antitumor and Anti-HIV Agents from Natural Products |
| Autore | Nakagawa-Goto Kyoko |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 |
| Descrizione fisica | 1 online resource (338 p.) |
| Soggetto topico | Research & information: general |
| Soggetto non controllato |
acute toxicity
allyl isothiocyanate Angelica dahurica anti-HIV antiangiogenic antioxidants antiproliferation antiproliferative activity antiretroviral agents antitumor activity apoptosis Artemisia absinthium L. aspidosperma-type benzyl isothiocyanate bladder cancer Bousigonia mekongensis BRAF inhibitor breast cancer butanolides caffeic acid cancer cancer multidrug resistance cancer stem cell Carpesium divaricatum cell cycle cell cycle arrest cervical cancer chemistry chemoprevention cisplatin coumarins curcumin analog cytotoxicity delcosine delpheline diterpenoid alkaloids DOTA drug development drug-drug interaction epithelial-to-mesenchymal transition essential oil flavonoids G2/M phase cell cycle arrest HaCaT cells HEF cell line hepatocellular carcinoma hepatoma cells Hernandia nymphaeifolia human tumor cell lines human tumor cells inflammation Ivalin kobusine lignan glycosides lipojesaconitine marine metabolites matrix metalloproteinase medicine melanoma melanoma and breast cancer cell line Mentha aquatica var. Kenting Water Mint metastasis mitochondria-mediated apoptosis monoterpenoid indole alkaloids natural agents natural phaeosphaeride A natural products NF-κB oral squamous cell carcinoma cells oxidative stress oxypeucedanin P-glycoprotein p53 phenethyl isothiocyanate phenolic acid pseudokobusine pterostilbene quercetin reactive oxygen species resveratrol SK-Hep-1 sulforaphane tamoxifen taxol total phenolic content transforming growth factor-β1 triterpenoids tubulin inhibitor tumor suppression two-stage skin carcinogenesis ursolic acid β-lapachone |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557504803321 |
Nakagawa-Goto Kyoko
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Drug Metabolism/Transport and Pharmacokinetics
| Drug Metabolism/Transport and Pharmacokinetics |
| Autore | Song Im-Sook |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 online resource (232 p.) |
| Soggetto topico |
Manufacturing industries
Medicine and Nursing |
| Soggetto non controllato |
acute renal failure
anti-obesity agent automatization BCRP biliary excretion breast cancer resistance protein Caco-2 carboxylesterase Carthamus tinctorius extract catalposide celecoxib cisplatin comparative pharmacokinetic study compatibility mechanism compound K creatinine clearance CYP3A4 cytochrome P450 cytochrome P450 enzymes diabetes dose-dependent pharmacokinetics drug absorption drug dosing drug interaction drug transporter drug-drug interaction DWP16001 efflux transporter EpiIntestinal first-pass fluorescence food-drug interactions gentamicin head-and-neck cancer healthy Korean subjects hepatic and intestinal first-pass effect hepatic CYP3A1(23) HPLC HSG4112 human hepatocytes in vitro human metabolism influx transporter inhibition mode inhibitor intestinal metabolism kidney distribution kinetic analysis large volume direct injection mertansine metabolism metformin modeling nonrenal clearance notoginseng total saponins oral availability organic cation transporter 2 P-gp pharmacokinetics physiologically based pharmacokinetic model population pharmacokinetic prazosin protopanaxadiol (PPD) quercetin rats real-time measurements renal clearance renal excretion repaglinide sodium-glucose cotransporter 2 (SGLT2) inhibitors stereoselectivity sulfasalazine sulfotransferase taxanes tiropramide tissue engineering tofacitinib transporter-enzyme interplay UDP-glucuronosyltransferase UDP-glucuronosyltransferases UHPLC-MS/MS verapamil |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557607703321 |
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Song Im-Sook
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Drug-Drug Interactions
| Drug-Drug Interactions |
| Autore | Kim Dong Hyun |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 online resource (242 p.) |
| Soggetto topico |
Biology, life sciences
Research & information: general |
| Soggetto non controllato |
(‒)-sophoranone
1A2 2B6 2C19 2C8 2C9 2D6 3A4 ADME adverse drug reactions biflavonoid chronic kidney disease competitive inhibition computational prediction CYP CYP1A1 CYP1A2 CYP2C9 CYP2D6 CYP3A CYP3A4 cytochrome P450 cytochromes P450 DDI Dexamethasone drug interaction drug interactions drug metabolism drug transporter drug-drug interaction drug-drug interactions expression fexofenadine gepants high plasma protein binding in silico in vitro in vivo inhibitor ixazomib Ketoconazole lasmiditan Lexicomp low permeability Loxoprofen mechanism-based inhibition metabolic DDI metabolism migraine monoclonal antibodies non-competitive inhibition O-desmethyltramadol OATP1B1 OATP1B3 organic anion transporting polypeptide 1A2 (OATP1A2) P-glycoprotein (P-gp) P450 pharmacokinetics physiologically-based pharmacokinetics plasma concentration polypharmacy potent inhibition QSAR regulation Rumex acetosa selamariscina A signal detection algorithms spontaneous reporting systems subset analysis substrate systemic exposure tadalafil ticagrelor tissue-specific tramadol tyrosine kinase inhibitors ubiquitination uridine 5'-diphosphoglucuronosyl transferase |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557666403321 |
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Kim Dong Hyun
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Recent Trends in Pharmaceutical Analytical Chemistry
| Recent Trends in Pharmaceutical Analytical Chemistry |
| Autore | Zacharis Constantinos K |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 online resource (166 p.) |
| Soggetto topico | Research & information: general |
| Soggetto non controllato |
adulteration
alnustone amantadine anwuligan baricitinib biomimetic chromatography cell-based bioassay contact-lens detergent derivatization dietary supplement doxorubicin drug-drug interaction fixed-dose combination folic acid gardneramine growth hormone hernandezine high throughput bar adsorptive microextraction in vitro permeability inflammatory bowel disease irbersartan ketamine lactone-rhodamine B LC-MS/MS long-acting Fc-fusion recombinant human growth hormone low-field NMR LVI-GC-MS(SIM) memantine method validation monoterpenoid indole alkaloid multivariate analysis n/a norketamine o-phthalaldehyde optode Partial Least Squares regression pharmacokinetic study pharmacokinetics polyhexamethylene biguanide hydrochloride predictive model quality control rat rats reporter gene assay rimantadine steroids stopped-flow thiopurine immunosuppressants tissue distribution UPLC-MS/MS urine zone fluidics |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557427303321 |
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Zacharis Constantinos K
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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