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Advances in Antifungal Development: Discovery of New Drugs and Drug Repurposing
| Advances in Antifungal Development: Discovery of New Drugs and Drug Repurposing |
| Autore | Kim Jong Heon |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 electronic resource (282 p.) |
| Soggetto topico |
Research & information: general
Biology, life sciences |
| Soggetto non controllato |
nanoparticles
fungi drug delivery systems marine biological synthesis myconanotechnology canesten clotrimazole vulvovaginal vaginitis mycosis candidosis yeast infection candida candida albicans vaginal health anticandidal activity indazole pyrazole 3-phenyl-1H-indazole drug design acetylsalicylic acid (ASA, aspirin) capsule CAP64 Cryptococcus membrane potential (ΔΨM) photodynamic treatment photosensitiser ultrastructure drug repurposing antifungals repositioning yeasts emerging fungi multidrug resistance therapeutic alternatives new targets Candida auris Aspergillus spp antifungal beta-glucan polycations Galleria mellonella model retinoids Candida spp onychomycosis Malassezia spp dermatophytes microbiology mycology all-trans retinoic acid Acanthamoeba free-living ameba Acanthamoeba keratitis isavuconazonium sulfate cyst drug drug discovery drug targets invasive aspergillosis treatment invasive fungal infections fission yeast cell wall β(1,3)-D-glucan synthase antifungal drugs echinocandin drugs echinocandin resistance Fks resistance hot spots cytokinesis septation cell separation cell integrity cell lysis sporotrichosis Felis catus quinones hydrazones zoonoses host-directed drug therapy azoles polyenes echinocandins viral infections azole synergy resistance Candida natural products |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | Advances in Antifungal Development |
| Record Nr. | UNINA-9910585935503321 |
Kim Jong Heon
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Celebrating Applied Sciences Reaches 20,000 Articles Milestone : Feature Papers in Applied Biosciences and Bioengineering Section
| Celebrating Applied Sciences Reaches 20,000 Articles Milestone : Feature Papers in Applied Biosciences and Bioengineering Section |
| Autore | Cappello Francesco |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 electronic resource (228 p.) |
| Soggetto topico |
Technology: general issues
Biotechnology |
| Soggetto non controllato |
biothiols
blood plasma gold nanoparticles colorimetric probes chaperone system Hsp60 gastritis gastric dysplasia gastric carcinogenesis intestinal metaplasia LAMP Salmonella ISO 16140:2016 food-borne validation specificity sensitivity accuracy kit elderberry Sambucus nigra L. juice concentrate storage effect phenolic compounds berries anthocyanins' stability polymeric color ABTS•+ antioxidant capacity endothelial glycocalyx inflammatory response fluid loading surgery post-operative albumin extravasation serum HSP90 gamma-delta T cells acute lymphoblastic leukaemia halophyte sea purslane minerals antioxidant activity novel ingredient epilepsy systems biology protein-protein interactions CNS Gibbs homology drug targets anti-epileptic drugs periodontitis inflammation oils volatile heart disease risk factors asthma chronic obstructive pulmonary disease COPD epithelial-mesenchymal trophic unit muco-microbiotic layer nanovesicles exosomes outer membrane vesicles microbiota spheroid organoid van der Waals force fluoropolymers adhesion microstamp extracellular vesicles liquid biopsy biomarkers tumor progression metastasis drug delivery halloysite nanoclay regenerative medicine tissue engineering wound healing stroke yoga balance disability depression levetiracetam critically ill patients population pharmacokinetic modeling simulated dosage schemes intensive care unit |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | Celebrating Applied Sciences Reaches 20,000 Articles Milestone |
| Record Nr. | UNINA-9910580215703321 |
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Cappello Francesco
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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In Silico Strategies for Prospective Drug Repositionings
| In Silico Strategies for Prospective Drug Repositionings |
| Autore | Udrescu Lucreția |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 electronic resource (288 p.) |
| Soggetto topico |
Medicine
Pharmaceutical industries |
| Soggetto non controllato |
COVID-19
drug repurposing topological data analysis persistent Betti function SARS-CoV-2 network-based pharmacology combination therapy nucleoside GS-441524 fluoxetine synergy antidepressant natural compounds QSAR molecular docking drug repositioning UK Biobank vaccine LC-2/ad cell line drug discovery docking MM-GBSA calculation molecular dynamics cytotoxicity assay GWAS multiple sclerosis oxidative stress repurposing ADME-Tox bioinformatics complex network analysis modularity clustering ATC code hidradenitis suppurativa acne inversa transcriptome proteome comorbid disorder biomarker signaling pathway druggable gene drug-repositioning MEK inhibitor MM/GBSA Glide docking MD simulation MM/PBSA single-cell RNA sequencing pulmonary fibrosis biological networks p38α MAPK allosteric inhibitors in silico screening computer-aided drug discovery network analysis psychiatric disorders medications psychiatry mental disorders toxoplasmosis Toxoplasma gondii in vitro screening drug targets drug-disease interaction target-disease interaction DPP4 inhibitors lipid rafts |
| ISBN | 3-0365-6133-1 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910639987703321 |
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Udrescu Lucreția
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Novel Treatment Strategies for Glioblastoma
| Novel Treatment Strategies for Glioblastoma |
| Autore | Stylli Stanley |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 electronic resource (268 p.) |
| Soggetto topico | Medicine |
| Soggetto non controllato |
glioblastoma
glioma temozolomide radiotherapy immunotherapy novel therapy personalized treatment drug repurposing invasion invadopodia ion channels gene therapy viral vectors brain tumor nanomedicine cancer stem cell targeted therapy brain cancer cell cycle differentiation proliferation RAS SRGAP2 stem cell TP53 glioblastoma multiforme GBM nerve/glial antigen 2 NG2 CK2 CX-4945 migration CRISPR/Cas9 anticancer anti-angiogenesis thyrointegrin αvβ3 PEG triazole tetrac P-bi-TAT P-m-TAT tetrac one-carbon metabolism de novo purine synthesis metabolic reprogramming metabolic treatment vaccine immune checkpoint inhibitors chimeric antigen receptor (CAR) T cells glioblastoma (GB) prolyl-oligopeptidase (POP) vascular endothelial growth factor (VEGF) transforming growth factor-β (TGF-β) angiopoietin (Ang) endothelial nitric oxide synthase (eNOS) newly diagnosed glioblastoma recurrent glioblastoma new trial design drug-inducible gene expression Mardepodect Regorafenib drug targets tumor antigens renin-angiotensin system pluripotent stem cells organoids cancer stem cells cancer stem cell niche tumor microenvironment |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557363703321 |
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Stylli Stanley
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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