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Biomarkers in Drug Hypersensitivity
| Biomarkers in Drug Hypersensitivity |
| Autore | Emanuela Corsini |
| Pubbl/distr/stampa | Frontiers Media SA, 2017 |
| Descrizione fisica | 1 online resource (104 p.) |
| Collana | Frontiers Research Topics |
| Soggetto topico | Pharmacology |
| Soggetto non controllato |
biomarkers
drug drug metabolism genotyping haptenization hypersensitivity models phenotyping |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910227346103321 |
Emanuela Corsini
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| Frontiers Media SA, 2017 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Cytochromes P450: Drug Metabolism, Bioactivation and Biodiversity 2.0
| Cytochromes P450: Drug Metabolism, Bioactivation and Biodiversity 2.0 |
| Autore | Dansette Patrick M |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 online resource (286 p.) |
| Soggetto topico | Research and information: general |
| Soggetto non controllato |
20-HETE
active site access channels Antibiotics arachidonic acid azole drugs Bacillus Bietti's crystalline dystrophy biosynthetic gene clusters cavities boundaries circulatory CYPs comparative analysis cryptococcus cryptococcus neoformans crystal structure Cyanobacteria CYP diversity analysis CYP128A1 CYP139A1 CYP2C8 CYP3A4 CYP4 genes CYP450 CYP51 Cytochrome b5 (CYB5) cytochrome P450 cytochrome P450 monooxygenase cytochrome P450 monooxygenases cytochrome P450 monooxygenenases cytochrome P450 reductase cytochromes P450 cytochromes P450 monooxygenases drug metabolism electron transfer electron-transfer (ET) enzyme substrate specificity exosomes extracellular vesicles extrahepatic tissues fatty acid fungal pathogens gene-cluster diversity percentage genetic polymorphisms genome data mining genome data-mining host metabolism human pathogens isoform lamellar ichthyosis mathematical formula mechanism-based inhibitor membrane protein menaquinone metabolism microsomal cytochrome P450 (CYP) minimal cost paths molecular dynamic simulations molecular dynamics simulation molecular functionality mutagenesis Mycobacterium Mycobacterium tuberculosis Mycobacterium tuberculosis H37Rv NADPH-cytochrome P450 reductase (CPR) non-ribosomal peptides P450 blooming P450 diversity percentage P450 profiling paclitaxel phylogenetic analysis plasma polyketides polymorphisms precision Cardio-Oncology precision medicine protein dynamics protein-membrane interactions protein-protein interaction reactive oxygen species RNA interference secondary metabolites SNPs Sogatella furcifera Streptomyces sulfoxaflor systems medicine terpenes transcriptome tremellomycetes trichosporon tuberculosis |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | Cytochromes P450 |
| Record Nr. | UNINA-9910557761103321 |
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Dansette Patrick M
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Drug-Drug Interactions
| Drug-Drug Interactions |
| Autore | Kim Dong Hyun |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 online resource (242 p.) |
| Soggetto topico |
Biology, life sciences
Research & information: general |
| Soggetto non controllato |
(‒)-sophoranone
1A2 2B6 2C19 2C8 2C9 2D6 3A4 ADME adverse drug reactions biflavonoid chronic kidney disease competitive inhibition computational prediction CYP CYP1A1 CYP1A2 CYP2C9 CYP2D6 CYP3A CYP3A4 cytochrome P450 cytochromes P450 DDI Dexamethasone drug interaction drug interactions drug metabolism drug transporter drug-drug interaction drug-drug interactions expression fexofenadine gepants high plasma protein binding in silico in vitro in vivo inhibitor ixazomib Ketoconazole lasmiditan Lexicomp low permeability Loxoprofen mechanism-based inhibition metabolic DDI metabolism migraine monoclonal antibodies non-competitive inhibition O-desmethyltramadol OATP1B1 OATP1B3 organic anion transporting polypeptide 1A2 (OATP1A2) P-glycoprotein (P-gp) P450 pharmacokinetics physiologically-based pharmacokinetics plasma concentration polypharmacy potent inhibition QSAR regulation Rumex acetosa selamariscina A signal detection algorithms spontaneous reporting systems subset analysis substrate systemic exposure tadalafil ticagrelor tissue-specific tramadol tyrosine kinase inhibitors ubiquitination uridine 5'-diphosphoglucuronosyl transferase |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557666403321 |
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Kim Dong Hyun
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Organs-on-chips
| Organs-on-chips |
| Autore | Tung Yi-Chung |
| Pubbl/distr/stampa | MDPI - Multidisciplinary Digital Publishing Institute, 2020 |
| Descrizione fisica | 1 online resource (262 p.) |
| Soggetto topico | History of engineering and technology |
| Soggetto non controllato |
3D cell culture
3D cell culture system angiogenesis barrier permeability beating force bio-mechanical property biomechanics biomimetic oxidation cardiac 3D tissue cell cell culture compression drug absorption drug efficacy drug hepatotoxicity drug metabolism endothelial cell activation epithelial-endothelial interface fluoroelastomer functional neuron imaging high-throughput screening human induced pluripotent Stem cell-derived cardiomyocytes (hiPS-CM) image-based screening integrated pump ischemia/reperfusion injury lattice light-sheet microscopy liver-on-a-chip lung epithelial cell mechanical cue membranes MEMS microfabrication microfluidic device microfluidics multi-culture n/a nanogrooves neuronal cell networks neuronal cells neuronal guidance organ-on-a-chip organ-on-a-chip (OOC) organ-on-chip organ-on-chips organoid organs-on-chips paracellular/transcellular transport passive delivery PDMS SH-SY5Y cells shear flow shear stress silicon spheroid array strain stress stretch surfactant protein syringe pump thrombolysis tissue engineering trans-epithelial electrical resistance vacuum chuck vascularization vascularized tumor model vessel branching |
| ISBN | 3-03928-918-7 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910404077903321 |
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Tung Yi-Chung
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| MDPI - Multidisciplinary Digital Publishing Institute, 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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