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A Meeting of Minds: In Recognition of the Contributions of Randall J. Cohrs
| A Meeting of Minds: In Recognition of the Contributions of Randall J. Cohrs |
| Autore | Grose Charles |
| Pubbl/distr/stampa | MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 electronic resource (424 p.) |
| Soggetto topico |
Research & information: general
Biology, life sciences |
| Soggetto non controllato |
varicella-zoster virus
Oka strain human herpesvirus 6 human herpesvirus 7 corticosteroids serious adverse event herpes zoster IL-6 IL-10 innate immunity VLT VLT-ORF63 CRISPR/Cas9 BAC mutagenesis flavivirus SARS-CoV-2 pandemic preparedness host-virus interactions prion vaccines interferon lambda virus herpes simplex virus type 1 herpes simplex virus type 2 neonatal herpesvirus infection HSV UL6 herpesvirus encephalitis herpesvirus hepatitis acyclovir HerpeSelect test viral sequencing HELLP syndrome lipids dengue virus acyl-CoA acyl-CoA thioesterase fatty acids membranes rheostat fatty acyl-CoA Marek's disease virus live-cell genome visualization lytic replication T cells latency genome integration TetO/TetR system varicella zoster virus reactivation genome cleavage AAV antiviral therapies HSV-1 cornea trigeminal ganglia interferon-γ interferon stimulatory genes TRIM21 HSV EBV KSHV MHV68 PIC transcription productive elongation mRNA rRNA tRNA herpes viral reactivation spaceflight dermatitis stress immune depression antiviral drugs bacterial artificial chromosome luciferase bioluminescence imaging skin organ culture humanized mice β-Coronavirus mouse hepatitis virus-A59/MHV-A59 mouse hepatitis virus-2/MHV2 spike protein fusion peptide/FP cell-to-cell fusion (fusogenicity) neuropathogenesis hepatitis demyelination structural rigidity simian varicella virus herpesvirus varicella VZV neuro-attenuated ORF7 vaccine antiviral COVID-19 drug discovery coronavirus spike protein Mpro RdRp PLpro skin epidermis keratinocytes epidermal differentiation cutaneous blistering lesions keratins autophagy immunity human neuron culture non-coding RNA CD8 T cell T-cell epitope NK cell KIR3DL1 HLA-B*57:01 herpes simplex virus zoster skin pathogenesis HSV-2 neurons cell culture varicella-zoster gene expression ganglion autopsy saliva salivary VZV DNA dengue viruses Aedes aegypti adaptive mutation |
| ISBN | 3-0365-5260-X |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | Meeting of Minds |
| Record Nr. | UNINA-9910619471403321 |
Grose Charles
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| MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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A Milestone in Frontiers in Pharmacology: 1,000 Published Papers in the Section Experimental Pharmacology and Drug Discovery
| A Milestone in Frontiers in Pharmacology: 1,000 Published Papers in the Section Experimental Pharmacology and Drug Discovery |
| Autore | Salomone Salvatore |
| Pubbl/distr/stampa | Frontiers Media SA, 2020 |
| Descrizione fisica | 1 online resource (266 p.) |
| Soggetto topico |
Pharmacology
Science: general issues |
| Soggetto non controllato |
drug action
drug discovery enzymes experimental pharmacology ion channels receptors transcription factors transporters |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | Milestone in Frontiers in Pharmacology |
| Record Nr. | UNINA-9910557483603321 |
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Salomone Salvatore
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| Frontiers Media SA, 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Actinomycetes : The Antibiotics Producers
| Actinomycetes : The Antibiotics Producers |
| Autore | Stegmann Evi |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 |
| Descrizione fisica | 1 online resource (362 p.) |
| Soggetto topico |
Biology, life sciences
Research & information: general |
| Soggetto non controllato |
(p)ppGpp
A40926 Actinoallomurus actinobacteria Actinobacteria actinomycetes acyltransferases Amycolatopsis antibiotic antibiotics antibiotics polyethers aromatic polyketide benz[a]naphthacene quinone biogeography biological activity biosynthesis biosynthetic gene cluster Cave microbiology chemical ecology comparative genomics culture-based approaches cyclases dalbavancin dbv cluster dereplication differentiation diversification drug discovery elicitors engineering extended polyketide chain FK506 genome mining geomicrobiology glycopeptide antibiotics Illumina sequencing LAL liquid cultures LuxR solo lysolipin metabolomics metagenomics microbiome diversity minimal PKS II morphology n/a natural products new bioactive compounds novel compounds omics pentacyclic angular polyphenol physical and chemical properties physicochemical screening polyadenylation polyketide synthases polyketides polynucleotide phosphorylase promoter rare Actinobacteria rare actinomycetes regulation regulatory genes resistance ribonuclease rishirilide RNA decay screening secondary metabolism secondary metabolite secondary metabolite biosynthetic gene clusters secondary metabolites secretion pathways secretory proteins siderophore signal peptides SMGC specialized metabolites strain streptomyces Streptomyces Streptomyces lividans Streptomyces tsukubaensis StrR structural diversity symbiosis tacrolimus teicoplanin tridecaketide unculturability van resistance genes β-lactamase β-lactamase inhibitor |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | Actinomycetes |
| Record Nr. | UNINA-9910557114803321 |
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Stegmann Evi
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Advances in Antifungal Development: Discovery of New Drugs and Drug Repurposing
| Advances in Antifungal Development: Discovery of New Drugs and Drug Repurposing |
| Autore | Kim Jong Heon |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 online resource (282 p.) |
| Soggetto topico |
Biology, life sciences
Research & information: general |
| Soggetto non controllato |
3-phenyl-1H-indazole
Acanthamoeba Acanthamoeba keratitis acetylsalicylic acid (ASA, aspirin) all-trans retinoic acid anticandidal activity antifungal antifungal drugs antifungals Aspergillus spp azole azoles beta-glucan biological synthesis candida Candida candida albicans Candida auris Candida spp candidosis canesten CAP64 capsule cell integrity cell lysis cell separation cell wall clotrimazole Cryptococcus cyst cytokinesis dermatophytes drug drug delivery systems drug design drug discovery drug repurposing drug targets echinocandin drugs echinocandin resistance echinocandins emerging fungi Felis catus fission yeast Fks resistance hot spots free-living ameba fungi Galleria mellonella model host-directed drug therapy hydrazones indazole invasive aspergillosis treatment invasive fungal infections isavuconazonium sulfate Malassezia spp marine membrane potential (ΔΨM) microbiology multidrug resistance mycology myconanotechnology mycosis n/a nanoparticles natural products new targets onychomycosis photodynamic treatment photosensitiser polycations polyenes pyrazole quinones repositioning resistance retinoids septation sporotrichosis synergy therapeutic alternatives ultrastructure vaginal health vaginitis viral infections vulvovaginal yeast infection yeasts zoonoses β(1,3)-D-glucan synthase |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | Advances in Antifungal Development |
| Record Nr. | UNINA-9910585935503321 |
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Kim Jong Heon
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Advancing Genomics for Rare Disease Diagnosis and Therapy Development
| Advancing Genomics for Rare Disease Diagnosis and Therapy Development |
| Autore | Liu Zhichao |
| Pubbl/distr/stampa | Frontiers Media SA, 2020 |
| Descrizione fisica | 1 online resource (297 p.) |
| Soggetto topico |
Pharmacology
Science: general issues |
| Soggetto non controllato |
diagnosis
drug discovery genomics NGS rare dieases |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557671603321 |
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Liu Zhichao
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| Frontiers Media SA, 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Anticancer Agents : Design, Synthesis and Evaluation
| Anticancer Agents : Design, Synthesis and Evaluation |
| Autore | Chen Qiao-Hong |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 online resource (606 p.) |
| Soggetto topico | Medicine and Nursing |
| Soggetto non controllato |
1,2,3-triazole
2H-benzo[e][1,2,4]thiadiazine 1,1-dioxide 3,6-dibromocarbazole 4-(pyridin-4-yloxy)benzamide 5-bromoindole 5-fluorouracil ABCB1 (P-glycoprotein) actin ADME allene amides/esters androgen receptor anti-cancer activity anti-neuroinflammation anti-ovarian cancer anti-tumor anticancer anticancer activity anticancer agent anticancer agents anticancer compounds antimitotic agents antioxidant activity antiproliferative activity antiproliferative agent antitumor antitumor activity apalutamide apoptosis aromatase benzimidazole benzofuran-pyrazole benzofurans beta-lapachone bivalency breast cancer c-Met carbazole cell cycle chemical synthesis chemoresistance chrysin analogues colchiceine colchicine amide colchicine analogs colchicine sulfonamide colon cancer computational docking coumarin crystal structure cyanopyridone cytotoxic activity cytotoxic properties cytotoxicity darolutamide DFT study dihydroartemisinin dihydropyranoindole docking docking studies drug discovery drug resistance E-stereoselective enzalutamide enzyme inhibition estrone derivatives flavonoid flavonoids gemcitabine HDAC inhibitors HeLa HepG2 hydrates hydrazine IGF-1R IL-12 immune modulation indoleamine 2,3-dioxygenase inflammation inhibitor K562 kinase inhibitor MCF-7 MDM2-p53 interaction migration mimetics molecular simulation MOLT-4 multidrug resistance (MDR) reversal N-substituted pyrazoline nanoparticles natural product neuroblastoma NIH3T3 o-nitro-benzyl organosilicon compounds ortho-quinones ovarian cancer overcoming drug resistance P-glycoprotein P-MAPA PARP inhibitor PARP-1 inhibition phenylpyrazolopyrimidine photoactivatable protecting groups PI3Ks PI3Kα inhibitor PI3Kδ inhibitors polyvalency prodrug prostate cancer PROTACs protein degradation protein kinase protein-protein interactions Pyrazole pyrazolopyridine pyridotriazine quinazolin-4(3H)-one quinazolin-4(3H)-thione regioselective salinomycin Schiff base SILA-409 (Alis-409) SILA-421 (Alis-421) Src substituted pyridine synergy synthesis Talazoparib tanshione IIA taxoids thiazolidinone Thienopyrimidine thienopyrimidinone thiocolchicine thiopene thioxotriazopyridine TLR signaling topoisomerase II inhibitor triazolothiadiazine triple-negative breast cancer tryptophan metabolism tubulin inhibitors tumor specificity urea virtual screening xanthones yeast-based assays zampanolide βIII-tubulin |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | Anticancer Agents |
| Record Nr. | UNINA-9910557129103321 |
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Chen Qiao-Hong
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Antiviral Agents
| Antiviral Agents |
| Autore | Adamson Catherine |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 |
| Descrizione fisica | 1 online resource (386 p.) |
| Soggetto topico |
Biology, life sciences
Research and information: general |
| Soggetto non controllato |
acteoside
acute/latent infection acyclovir adoptive cell therapy antipsychotic drug antiviral antiviral activity antiviral agent antiviral agents antiviral drug antiviral effect antiviral inhibitor antiviral strategies branched peptides brevilin A Burkitt lymphoma cells C-FRA cathelicidins central nervous system chemical footprinting Clerodendrum trichotomum clozapine combination antiretroviral therapy (cART) congenital infection coxsackievirus B4 CRISPR/Cas cytomegalovirus defensins dried blood spots dried plasma spots drug discovery endocytosis enteroviruses epigallocatechin gallate Epstein-Barr virus Ethiopia flavivirus flavonoids fluoxetine furin inhibitor ganciclovir genistein ginsenoside Rg1 glycosphingolipids HCMV vaccine hemagglutinin (HA) heparan sulfate hepatitis C virus hepcidins herpes B virus herpes viruses herpesvirus HIV human antimicrobial peptides human immunodeficiency virus ie-1 gene IE1 IE2 immediate-early influenza A virus influenza A virus (IAV) Japanese encephalitis virus latent infection lectin lipid biosynthesis LUMS1 lytic gene expression macacine herpesvirus-1 measles virus microvirin mutations n/a neural stem cells NF-κB signaling pathway non-immunogenic NS5 nucleic acid-based therapeutic approach nucleoside analogues oleanane-type derivatives orthohantavirus pediatrics PEI persistent infection phenyl-benzotriazoles Plantago asiatica polyethylenimine Porcine circovirus type 2 porcine reproductive and respiratory syndrome virus pre-treatment drug resistance precursor membrane protein pro-inflammatory factor prodrugs protein drugs ProTides PRRSV quantitative real-time PCR replication resistance Rev response element ribozyme RNA interference RNA-dependent RNA polymerase RSV sesquiterpene lactone SHAPE small molecule sphingolipids Surveyor nuclease mutation detection assay TALEN therapeutic effects therapeutic strategies transferrins treatments tropism viral entry virion internalization virus attachment virus entry inhibitors viruses Zika virus |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557448703321 |
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Adamson Catherine
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Bioactive Compounds from Marine-Derived Aspergillus, Penicillium, Talaromyces and Trichoderma Species
| Bioactive Compounds from Marine-Derived Aspergillus, Penicillium, Talaromyces and Trichoderma Species |
| Autore | Nicoletti Rosario |
| Pubbl/distr/stampa | MDPI - Multidisciplinary Digital Publishing Institute, 2019 |
| Descrizione fisica | 1 online resource (134 p.) |
| Soggetto topico | Biology, life sciences |
| Soggetto non controllato |
antibacterial
antibacterial activity antifungal activity Aspergillaceae Aspergillus Aspergillus candidus Aspergillus clavatus aspetritone bioactive products bis-indolyl benzenoids BK (Maxi-K) channel breast cancer breviane spiroditerpenoid candidusin chromone coumarin cytotoxic cytotoxicities cytotoxicity diastereomers diterpenoid drug discovery ECD calculations EGFR endophytic fungi gefitinib HER2 hydroxypyrrolidine IDH1 inhibitory activity indole-diterpenoids lapatinib mangrove endophytic fungus mangroves marine-derived fungi n/a NMR data calculations Penicillium raistrickii Penicillium sp. TJ403-1 penitrem A polyketides secondary metabolites sesquiterpenoid sponge-associated fungus sterone Talaromyces Talaromyces purpurogenus thermo-change strategy TNF-? |
| ISBN | 3-03897-981-3 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910346857703321 |
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Nicoletti Rosario
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| MDPI - Multidisciplinary Digital Publishing Institute, 2019 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Bioactive Molecules from Extreme Environments II
| Bioactive Molecules from Extreme Environments II |
| Autore | Giordano Daniela (Researcher) |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 online resource (336 p.) |
| Soggetto topico |
Chemistry
Research & information: general |
| Soggetto non controllato |
(DFT)-UV-Vis spectral calculation
13C-NMR chemical shift linear and multiple regression 3-amino-2-pyrrolidinone absorption maxima in the near infrared region Antarctic bacteria Antarctica Antarctica sponge-derived fungus anti-food allergy antibacterial antibiotics antifungal activity antimicrobial peptides Arctic Arctic/Antarctic Aspergillus insulicola Bacillus amyloliquefaciens bioactive compound biomaterials biotechnological application chemical ecology crustin cyclic tripeptides deep sea natural products deep-sea hydrothermal vent deep-sea microorganism Dermacoccus abyssi MT 1.1T dermacozine DP4 calculation drug discovery freeze-drying fungal metabolites fungus Fusarium oxysporum f. sp. cubense Gastropoda green synthesis iturin A5 lipid A lipopeptide Lipopolysaccharide (LPS) lutein MALDI-TOF mass spectrometry Marfey's method Mariana Trench marine bioprospecting marine biotechnology marine natural product marine natural products metal microalgae Mollusca Muriellopsis mycalols n/a nanotechnology Paenibacillus Panama disease Penicillium griseofulvum phenoxazine psychrophiles quinone reductase shrimp sponges spray drying structural characterization supercritical fluid extraction Svalbard terpene terpenoid |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557343003321 |
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Giordano Daniela (Researcher)
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Bioactive Molecules from Marine Microorganisms
| Bioactive Molecules from Marine Microorganisms |
| Autore | Mazur-Marzec Hanna |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 online resource (172 p.) |
| Soggetto topico | Medicine |
| Soggetto non controllato |
aeruginosamides
anti-cancer activity anti-inflammatory anti-inflammatory activity anti-microbial antiproliferative Aspergillus terreus Aspergillus versicolor bianthraquinones biotechnology chromone derivatives cyanobacteria Cylindrotheca closterium cytotocxic activity cytotoxicity deep-sea-derived fungus diatoms dihydroisocoumarins diketopiperazine enantiomers diketopiperazines drug discovery ECD calculation ecology enantiomers endophyte fungus Epicoccum nigrum genetic dereplication Limnoraphis mangrove Streptomyces marine biotechnology marine-derived fungus meroterpenoids microviridin ncp gene cluster nonribosomal peptide synthetase Nostoc nostocyclopeptides oligopeptide Penicillium citrinum Stemphylium sp thiodiketopiperazines |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557468803321 |
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Mazur-Marzec Hanna
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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