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A Meeting of Minds: In Recognition of the Contributions of Randall J. Cohrs
| A Meeting of Minds: In Recognition of the Contributions of Randall J. Cohrs |
| Autore | Grose Charles |
| Pubbl/distr/stampa | MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 electronic resource (424 p.) |
| Soggetto topico |
Research & information: general
Biology, life sciences |
| Soggetto non controllato |
varicella-zoster virus
Oka strain human herpesvirus 6 human herpesvirus 7 corticosteroids serious adverse event herpes zoster IL-6 IL-10 innate immunity VLT VLT-ORF63 CRISPR/Cas9 BAC mutagenesis flavivirus SARS-CoV-2 pandemic preparedness host-virus interactions prion vaccines interferon lambda virus herpes simplex virus type 1 herpes simplex virus type 2 neonatal herpesvirus infection HSV UL6 herpesvirus encephalitis herpesvirus hepatitis acyclovir HerpeSelect test viral sequencing HELLP syndrome lipids dengue virus acyl-CoA acyl-CoA thioesterase fatty acids membranes rheostat fatty acyl-CoA Marek's disease virus live-cell genome visualization lytic replication T cells latency genome integration TetO/TetR system varicella zoster virus reactivation genome cleavage AAV antiviral therapies HSV-1 cornea trigeminal ganglia interferon-γ interferon stimulatory genes TRIM21 HSV EBV KSHV MHV68 PIC transcription productive elongation mRNA rRNA tRNA herpes viral reactivation spaceflight dermatitis stress immune depression antiviral drugs bacterial artificial chromosome luciferase bioluminescence imaging skin organ culture humanized mice β-Coronavirus mouse hepatitis virus-A59/MHV-A59 mouse hepatitis virus-2/MHV2 spike protein fusion peptide/FP cell-to-cell fusion (fusogenicity) neuropathogenesis hepatitis demyelination structural rigidity simian varicella virus herpesvirus varicella VZV neuro-attenuated ORF7 vaccine antiviral COVID-19 drug discovery coronavirus spike protein Mpro RdRp PLpro skin epidermis keratinocytes epidermal differentiation cutaneous blistering lesions keratins autophagy immunity human neuron culture non-coding RNA CD8 T cell T-cell epitope NK cell KIR3DL1 HLA-B*57:01 herpes simplex virus zoster skin pathogenesis HSV-2 neurons cell culture varicella-zoster gene expression ganglion autopsy saliva salivary VZV DNA dengue viruses Aedes aegypti adaptive mutation |
| ISBN | 3-0365-5260-X |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | Meeting of Minds |
| Record Nr. | UNINA-9910619471403321 |
Grose Charles
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| MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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A Milestone in Frontiers in Pharmacology: 1,000 Published Papers in the Section Experimental Pharmacology and Drug Discovery
| A Milestone in Frontiers in Pharmacology: 1,000 Published Papers in the Section Experimental Pharmacology and Drug Discovery |
| Autore | Salomone Salvatore |
| Pubbl/distr/stampa | Frontiers Media SA, 2020 |
| Descrizione fisica | 1 electronic resource (266 p.) |
| Soggetto topico |
Science: general issues
Pharmacology |
| Soggetto non controllato |
experimental pharmacology
drug discovery drug action receptors enzymes ion channels transporters transcription factors |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | Milestone in Frontiers in Pharmacology |
| Record Nr. | UNINA-9910557483603321 |
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Salomone Salvatore
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| Frontiers Media SA, 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Actinomycetes : The Antibiotics Producers
| Actinomycetes : The Antibiotics Producers |
| Autore | Stegmann Evi |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 |
| Descrizione fisica | 1 electronic resource (362 p.) |
| Soggetto topico |
Research & information: general
Biology, life sciences |
| Soggetto non controllato |
Streptomyces
biogeography comparative genomics diversification secondary metabolite biosynthetic gene clusters SMGC natural products streptomyces rishirilide biosynthesis polyketides polynucleotide phosphorylase ribonuclease regulation promoter RNA decay polyadenylation (p)ppGpp antibiotic antibiotics geomicrobiology Illumina sequencing microbiome diversity Actinobacteria Cave microbiology secondary metabolite rare Actinobacteria Amycolatopsis unculturability siderophore glycopeptide antibiotics dbv cluster regulatory genes StrR LAL LuxR solo dalbavancin A40926 Streptomyces lividans secretion pathways secretory proteins signal peptides actinomycetes teicoplanin van resistance genes Streptomyces tsukubaensis tacrolimus FK506 omics screening secondary metabolism differentiation elicitors morphology liquid cultures metagenomics rare actinomycetes dereplication metabolomics genome mining secondary metabolites novel compounds physicochemical screening physical and chemical properties structural diversity biological activity Actinoallomurus antibiotics polyethers lysolipin minimal PKS II cyclases benz[a]naphthacene quinone tridecaketide aromatic polyketide pentacyclic angular polyphenol extended polyketide chain actinobacteria β-lactamase resistance β-lactamase inhibitor polyketide synthases acyltransferases engineering new bioactive compounds symbiosis drug discovery chemical ecology culture-based approaches strain specialized metabolites biosynthetic gene cluster |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | Actinomycetes |
| Record Nr. | UNINA-9910557114803321 |
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Stegmann Evi
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Advances in Antifungal Development: Discovery of New Drugs and Drug Repurposing
| Advances in Antifungal Development: Discovery of New Drugs and Drug Repurposing |
| Autore | Kim Jong Heon |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 electronic resource (282 p.) |
| Soggetto topico |
Research & information: general
Biology, life sciences |
| Soggetto non controllato |
nanoparticles
fungi drug delivery systems marine biological synthesis myconanotechnology canesten clotrimazole vulvovaginal vaginitis mycosis candidosis yeast infection candida candida albicans vaginal health anticandidal activity indazole pyrazole 3-phenyl-1H-indazole drug design acetylsalicylic acid (ASA, aspirin) capsule CAP64 Cryptococcus membrane potential (ΔΨM) photodynamic treatment photosensitiser ultrastructure drug repurposing antifungals repositioning yeasts emerging fungi multidrug resistance therapeutic alternatives new targets Candida auris Aspergillus spp antifungal beta-glucan polycations Galleria mellonella model retinoids Candida spp onychomycosis Malassezia spp dermatophytes microbiology mycology all-trans retinoic acid Acanthamoeba free-living ameba Acanthamoeba keratitis isavuconazonium sulfate cyst drug drug discovery drug targets invasive aspergillosis treatment invasive fungal infections fission yeast cell wall β(1,3)-D-glucan synthase antifungal drugs echinocandin drugs echinocandin resistance Fks resistance hot spots cytokinesis septation cell separation cell integrity cell lysis sporotrichosis Felis catus quinones hydrazones zoonoses host-directed drug therapy azoles polyenes echinocandins viral infections azole synergy resistance Candida natural products |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | Advances in Antifungal Development |
| Record Nr. | UNINA-9910585935503321 |
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Kim Jong Heon
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Advancing Genomics for Rare Disease Diagnosis and Therapy Development
| Advancing Genomics for Rare Disease Diagnosis and Therapy Development |
| Autore | Liu Zhichao |
| Pubbl/distr/stampa | Frontiers Media SA, 2020 |
| Descrizione fisica | 1 electronic resource (297 p.) |
| Soggetto topico |
Science: general issues
Pharmacology |
| Soggetto non controllato |
rare dieases
NGS genomics diagnosis drug discovery |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557671603321 |
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Liu Zhichao
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| Frontiers Media SA, 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Anticancer Agents : Design, Synthesis and Evaluation
| Anticancer Agents : Design, Synthesis and Evaluation |
| Autore | Chen Qiao-Hong |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 electronic resource (606 p.) |
| Soggetto topico | Medicine |
| Soggetto non controllato |
benzofurans
chemical synthesis cytotoxic properties HeLa MOLT-4 K562 anticancer anti-neuroinflammation coumarin dihydroartemisinin flavonoids allene E-stereoselective regioselective anti-cancer activity cyanopyridone substituted pyridine pyridotriazine pyrazolopyridine thioxotriazopyridine anticancer activity HepG2 antitumor activity computational docking MDM2-p53 interaction xanthones yeast-based assays estrone derivatives hydrazine N-substituted pyrazoline anti-ovarian cancer topoisomerase II inhibitor kinase inhibitor antiproliferative agent urea synthesis antiproliferative activity apoptosis indoleamine 2,3-dioxygenase inhibitor anti-tumor immune modulation tryptophan metabolism taxoids βIII-tubulin P-glycoprotein drug resistance thiopene thienopyrimidinone thiazolidinone breast cancer benzofuran–pyrazole nanoparticles cytotoxic activity PARP-1 inhibition 3,6-dibromocarbazole 5-bromoindole carbazole actin migration Thienopyrimidine Pyrazole PI3Kα inhibitor quinazolin-4(3H)-one quinazolin-4(3H)-thione Schiff base antioxidant activity DFT study ortho-quinones beta-lapachone tanshione IIA PI3Ks PI3Kδ inhibitors 2H-benzo[e][1,2,4]thiadiazine 1,1-dioxide anticancer agents protein–protein interactions virtual screening mimetics drug discovery bivalency polyvalency antitumor cell cycle ovarian cancer P-MAPA IL-12 TLR signaling inflammation chemoresistance 4-(pyridin-4-yloxy)benzamide 1,2,3-triazole c-Met natural product anticancer agent zampanolide Talazoparib PARP inhibitor prodrug o-nitro-benzyl photoactivatable protecting groups salinomycin overcoming drug resistance tumor specificity synergy 5-fluorouracil gemcitabine amides/esters colchicine analogs thiocolchicine colchiceine antimitotic agents hydrates dihydropyranoindole HDAC inhibitors neuroblastoma aromatase MCF-7 NIH3T3 benzimidazole triazolothiadiazine docking ADME organosilicon compounds SILA-409 (Alis-409) SILA-421 (Alis-421) multidrug resistance (MDR) reversal ABCB1 (P-glycoprotein) colon cancer colchicine amide colchicine sulfonamide tubulin inhibitors docking studies crystal structure PROTACs protein degradation IGF-1R Src protein kinase phenylpyrazolopyrimidine enzyme inhibition molecular simulation androgen receptor prostate cancer enzalutamide apalutamide darolutamide triple-negative breast cancer cytotoxicity chrysin analogues flavonoid anticancer compounds |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | Anticancer Agents |
| Record Nr. | UNINA-9910557129103321 |
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Chen Qiao-Hong
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Antiviral Agents
| Antiviral Agents |
| Autore | Adamson Catherine |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 |
| Descrizione fisica | 1 electronic resource (386 p.) |
| Soggetto topico |
Research & information: general
Biology, life sciences |
| Soggetto non controllato |
Zika virus
nucleoside analogues antiviral agents NS5 prodrugs ProTides neural stem cells RNA-dependent RNA polymerase cytomegalovirus latent infection TALEN Surveyor nuclease mutation detection assay ie-1 gene quantitative real-time PCR Epstein-Barr virus herpes viruses lytic gene expression Burkitt lymphoma cells clozapine antipsychotic drug antiviral drug enteroviruses coxsackievirus B4 persistent infection fluoxetine resistance mutations herpes B virus macacine herpesvirus-1 genistein flavonoids acyclovir ganciclovir Plantago asiatica Clerodendrum trichotomum RSV therapeutic effects acteoside human antimicrobial peptides antiviral strategies defensins cathelicidins hepcidins transferrins influenza A virus brevilin A antiviral sesquiterpene lactone replication PRRSV polyethylenimine PEI virion internalization endocytosis HIV pediatrics Ethiopia pre-treatment drug resistance combination antiretroviral therapy (cART) dried plasma spots dried blood spots sphingolipids glycosphingolipids viruses lipid biosynthesis flavivirus Japanese encephalitis virus furin inhibitor precursor membrane protein measles virus central nervous system tropism treatments porcine reproductive and respiratory syndrome virus ginsenoside Rg1 antiviral activity pro-inflammatory factor NF-κB signaling pathway acute/latent infection congenital infection antiviral agent therapeutic strategies nucleic acid-based therapeutic approach HCMV vaccine adoptive cell therapy Rev response element chemical footprinting SHAPE drug discovery branched peptides herpesvirus immediate-early IE1 IE2 ribozyme RNA interference CRISPR/Cas small molecule orthohantavirus phenyl-benzotriazoles C-FRA Porcine circovirus type 2 epigallocatechin gallate heparan sulfate antiviral effect virus attachment microvirin lectin human immunodeficiency virus hepatitis C virus antiviral inhibitor non-immunogenic viral entry protein drugs LUMS1 oleanane-type derivatives influenza A virus (IAV) virus entry inhibitors hemagglutinin (HA) |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557448703321 |
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Adamson Catherine
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Bioactive Compounds from Marine-Derived Aspergillus, Penicillium, Talaromyces and Trichoderma Species
| Bioactive Compounds from Marine-Derived Aspergillus, Penicillium, Talaromyces and Trichoderma Species |
| Autore | Nicoletti Rosario |
| Pubbl/distr/stampa | MDPI - Multidisciplinary Digital Publishing Institute, 2019 |
| Descrizione fisica | 1 electronic resource (134 p.) |
| Soggetto non controllato |
antibacterial activity
Talaromyces purpurogenus lapatinib antibacterial hydroxypyrrolidine bis-indolyl benzenoids penitrem A cytotoxicities sesquiterpenoid secondary metabolites drug discovery sponge-associated fungus candidusin Penicillium sp. TJ403-1 coumarin gefitinib bioactive products Aspergillaceae indole-diterpenoids mangroves diterpenoid Penicillium raistrickii ECD calculations Talaromyces marine-derived fungi BK (Maxi-K) channel polyketides EGFR chromone aspetritone Aspergillus breviane spiroditerpenoid endophytic fungi cytotoxic cytotoxicity breast cancer mangrove endophytic fungus IDH1 inhibitory activity NMR data calculations antifungal activity Aspergillus candidus diastereomers TNF-? sterone Aspergillus clavatus HER2 thermo-change strategy |
| ISBN | 3-03897-981-3 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910346857703321 |
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Nicoletti Rosario
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| MDPI - Multidisciplinary Digital Publishing Institute, 2019 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Bioactive Molecules from Extreme Environments II
| Bioactive Molecules from Extreme Environments II |
| Autore | Giordano Daniela (Researcher) |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 electronic resource (336 p.) |
| Soggetto topico |
Research & information: general
Chemistry |
| Soggetto non controllato |
Arctic/Antarctic
marine bioprospecting marine natural product terpene terpenoid biotechnological application drug discovery microalgae Muriellopsis spray drying freeze-drying lutein supercritical fluid extraction cyclic tripeptides antibacterial Antarctica sponge-derived fungus Aspergillus insulicola psychrophiles Antarctic bacteria Lipopolysaccharide (LPS) lipid A structural characterization MALDI-TOF mass spectrometry marine natural products Mollusca Gastropoda chemical ecology crustin antimicrobial peptides shrimp deep-sea hydrothermal vent deep-sea microorganism fungus Penicillium griseofulvum anti-food allergy fungal metabolites Paenibacillus Arctic Svalbard Marfey’s method DP4 calculation quinone reductase lipopeptide 3-amino-2-pyrrolidinone green synthesis biomaterials metal antibiotics nanotechnology deep sea natural products Mariana Trench Dermacoccus abyssi MT 1.1T 13C-NMR chemical shift linear and multiple regression (DFT)-UV-Vis spectral calculation phenoxazine dermacozine absorption maxima in the near infrared region Antarctica sponges mycalols marine biotechnology antifungal activity Bacillus amyloliquefaciens Panama disease Fusarium oxysporum f. sp. cubense bioactive compound iturin A5 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557343003321 |
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Giordano Daniela (Researcher)
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Bioactive Molecules from Marine Microorganisms
| Bioactive Molecules from Marine Microorganisms |
| Autore | Mazur-Marzec Hanna |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 electronic resource (172 p.) |
| Soggetto topico | Medicine |
| Soggetto non controllato |
marine-derived fungus
Aspergillus terreus thiodiketopiperazines dihydroisocoumarins Epicoccum nigrum deep-sea-derived fungus diketopiperazine enantiomers cytotocxic activity diatoms marine biotechnology anti-inflammatory drug discovery Cylindrotheca closterium mangrove Streptomyces genetic dereplication anti-microbial antiproliferative endophyte fungus Aspergillus versicolor diketopiperazines ECD calculation enantiomers bianthraquinones meroterpenoids anti-inflammatory activity Stemphylium sp cyanobacteria nostocyclopeptides Nostoc ncp gene cluster nonribosomal peptide synthetase aeruginosamides Limnoraphis cytotoxicity oligopeptide microviridin biotechnology ecology Penicillium citrinum chromone derivatives anti-cancer activity |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557468803321 |
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Mazur-Marzec Hanna
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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