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Anticancer Agents : Design, Synthesis and Evaluation
| Anticancer Agents : Design, Synthesis and Evaluation |
| Autore | Chen Qiao-Hong |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 electronic resource (606 p.) |
| Soggetto topico | Medicine |
| Soggetto non controllato |
benzofurans
chemical synthesis cytotoxic properties HeLa MOLT-4 K562 anticancer anti-neuroinflammation coumarin dihydroartemisinin flavonoids allene E-stereoselective regioselective anti-cancer activity cyanopyridone substituted pyridine pyridotriazine pyrazolopyridine thioxotriazopyridine anticancer activity HepG2 antitumor activity computational docking MDM2-p53 interaction xanthones yeast-based assays estrone derivatives hydrazine N-substituted pyrazoline anti-ovarian cancer topoisomerase II inhibitor kinase inhibitor antiproliferative agent urea synthesis antiproliferative activity apoptosis indoleamine 2,3-dioxygenase inhibitor anti-tumor immune modulation tryptophan metabolism taxoids βIII-tubulin P-glycoprotein drug resistance thiopene thienopyrimidinone thiazolidinone breast cancer benzofuran–pyrazole nanoparticles cytotoxic activity PARP-1 inhibition 3,6-dibromocarbazole 5-bromoindole carbazole actin migration Thienopyrimidine Pyrazole PI3Kα inhibitor quinazolin-4(3H)-one quinazolin-4(3H)-thione Schiff base antioxidant activity DFT study ortho-quinones beta-lapachone tanshione IIA PI3Ks PI3Kδ inhibitors 2H-benzo[e][1,2,4]thiadiazine 1,1-dioxide anticancer agents protein–protein interactions virtual screening mimetics drug discovery bivalency polyvalency antitumor cell cycle ovarian cancer P-MAPA IL-12 TLR signaling inflammation chemoresistance 4-(pyridin-4-yloxy)benzamide 1,2,3-triazole c-Met natural product anticancer agent zampanolide Talazoparib PARP inhibitor prodrug o-nitro-benzyl photoactivatable protecting groups salinomycin overcoming drug resistance tumor specificity synergy 5-fluorouracil gemcitabine amides/esters colchicine analogs thiocolchicine colchiceine antimitotic agents hydrates dihydropyranoindole HDAC inhibitors neuroblastoma aromatase MCF-7 NIH3T3 benzimidazole triazolothiadiazine docking ADME organosilicon compounds SILA-409 (Alis-409) SILA-421 (Alis-421) multidrug resistance (MDR) reversal ABCB1 (P-glycoprotein) colon cancer colchicine amide colchicine sulfonamide tubulin inhibitors docking studies crystal structure PROTACs protein degradation IGF-1R Src protein kinase phenylpyrazolopyrimidine enzyme inhibition molecular simulation androgen receptor prostate cancer enzalutamide apalutamide darolutamide triple-negative breast cancer cytotoxicity chrysin analogues flavonoid anticancer compounds |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | Anticancer Agents |
| Record Nr. | UNINA-9910557129103321 |
Chen Qiao-Hong
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Bioactive Natural Products from the Red Sea
| Bioactive Natural Products from the Red Sea |
| Autore | Rateb Mostafa |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 electronic resource (152 p.) |
| Soggetto topico | Research & information: general |
| Soggetto non controllato |
Aspergillus falconensis
OSMAC azaphilones X-ray diffraction NF-κB inhibition LC-HRESIMS Stylissa carteri ceramide cerebroside docking cytotoxic activity co-cultivation phenazine sponge-associated actinomycetes antibacterial antibiofilm DNA gyrase pyruvate kinase ergosterol derivative metabolic analysis docking studies seagrass Thalassodendron ciliatum Red Sea sponges marine actinomycetes Streptomyces coelicolor LY001 halogenated 3-phenylpropanoic acid derivatives diketopiperazine alkaloids structural determinations antimicrobial activities Red Sea marine natural products marine organisms biodiversity marine metagenomics bioactivity Sinularia polydactyla soft coral steroids cytotoxic anti-inflammatory neuroprotective androgen receptor Actinokineospora Rhodococcus co-culture metabolomics antimalarial epicotripeptin phragamide Epicoccum Alternaria antimicrobial |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557540903321 |
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Rateb Mostafa
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Cholinesterase Research
| Cholinesterase Research |
| Autore | Korabecny Jan |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 electronic resource (223 p.) |
| Soggetto topico | Medicine |
| Soggetto non controllato |
Amaryllidaceae
Narcissus pseudonarcissus cv. Carlton alkaloids carltonine A-C Alzheimer's disease butyrylcholinesterase docking studies organophosphorus nerve agents oxime cholinesterase reactivation ventilation pharmacodynamics blood-brain barrier crossing acetylcholinesterase inhibitors bone healing osseointegration donepezil hemostasis acetylcholinesterase inhibitor dementia zebrafish behavior Alzheimer disease antioxidants butyrylcholinesterase inhibitors molecular modelling nutraceuticals phytochemicals acetylcholinesterase slow-binding inhibition transition state analog organophosphorus osmotic stress neutron scattering molecular dynamics MD simulations fluorene in vitro in silico multi-target directed ligands N-methyl-d-aspartate receptor molecular modeling reactivators reactivation process organophosphates docking hydrolysis molecular recognition catalysis inhibition |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557764703321 |
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Korabecny Jan
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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